Lewis Base Catalysis In Organic Synthesis

Author : Edwin Vedejs,Scott E. Denmark
Publisher : John Wiley & Sons
Page : 1488 pages
File Size : 53,5 Mb
Release : 2016-07-28
Category : Science
ISBN : 9783527675159

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Lewis Base Catalysis in Organic Synthesis by Edwin Vedejs,Scott E. Denmark Pdf

This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an extremely wide variety of preparatively useful transformations and is particularly effective for enantioselectively constructing new stereogenic centers. As electron-pair donors, Lewis bases can influence the rate and stereochemical course of myriad synthetic organic reactions. The book presents the conceptual/mechanistic principles that underlie Lewis base catalysis, and then builds upon that foundation with a thorough presentation of many different reaction types. And last but not least, the editors, Prof. Edwin Vedejs and Prof. Scott E. Denmark, are without doubt the leaders in this emerging field and have compiled high quality contributions from an impressive collection of international experts.

Author : Edwin Vedejs,Scott E. Denmark
Publisher : John Wiley & Sons
Page : 1476 pages
File Size : 42,6 Mb
Release : 2016-10-10
Category : Science
ISBN : 9783527336180

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Lewis Base Catalysis in Organic Synthesis, 3 Volume Set by Edwin Vedejs,Scott E. Denmark Pdf

This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an extremely wide variety of preparatively useful transformations and is particularly effective for enantioselectively constructing new stereogenic centers. As electron-pair donors, Lewis bases can influence the rate and stereochemical course of myriad synthetic organic reactions. The book presents the conceptual/mechanistic principles that underlie Lewis base catalysis, and then builds upon that foundation with a thorough presentation of many different reaction types. And last but not least, the editors, Prof. Edwin Vedejs and Prof. Scott E. Denmark, are without doubt the leaders in this emerging field and have compiled high quality contributions from an impressive collection of international experts.

Author : René Peters
Publisher : John Wiley & Sons
Page : 452 pages
File Size : 42,9 Mb
Release : 2015-04-27
Category : Technology & Engineering
ISBN : 9783527336890

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Cooperative Catalysis by René Peters Pdf

Written by experts in the field, this is a much-needed overview of the rapidly emerging field of cooperative catalysis. The authors focus on the design and development of novel high-performance catalysts for applications in organic synthesis (particularly asymmetric synthesis), covering a broad range of topics, from the latest progress in Lewis acid / Br?nsted base catalysis to e.g. metal-assisted organo catalysis, cooperative metal/enzyme catalysis, and cooperative catalysis in polymerization reactions and on solid surfaces. The chapters are classified according to the type of cooperating activating groups, and describe in detail the different strategies of cooperative activation, highlighting their respective advantages and pitfalls. As a result, readers will learn about the different concepts of cooperative catalysis, their corresponding modes of operation and their applications, thus helping to find a solution to a specific synthetic catalysis problem.

Author : Lukas J. Gooßen
Publisher : Springer
Page : 342 pages
File Size : 43,6 Mb
Release : 2012-10-30
Category : Science
ISBN : 9783642342868

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Inventing Reactions by Lukas J. Gooßen Pdf

Barry Trost: Transition metal catalyzed allylic alkylation.- Jeffrey W. Bode: Reinventing Amide Bond Formation.- Naoto Chatani and Mamoru Tobisu: Catalytic Transformations Involving the Cleavage of C-OMe Bonds.- Gregory L. Beutner and Scott E. Denmark: The Interplay of Invention, Observation and Discovery in the Development of Lewis Base Activation of Lewis Acids for Catalytic Enantioselective Synthesis.- David R. Stuart and Keith Fagnou: The Discovery and Development of a Palladium(II)-Catalyzed Oxidative Cross-Coupling of Two Unactivated Arenes.- Lukas Gooßen and Käthe Gooßen: Decarboxylative Cross-Coupling Reactions.- A. Stephen K. Hashmi: Gold-Catalyzed Organic Reactions.- Ben List: Developing Catalytic Asymmetric Acetalizations.- Steven M. Bischof, Brian G. Hashiguchi, Michael M. Konnick, and Roy A. Periana: The De NovoDesign of CH Bond Hydroxylation Catalysts.- Benoit Cardinal-David, Karl A. Scheidt: Carbene Catalysis: Beyond the Benzoin and Stetter Reactions.- Kenso Soai and Tsuneomi Kawasaki: Asymmetric autocatalysis of pyrimidyl alkanol.- Douglas C. Behenna and Brian M. Stoltz: Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents. Hisashi Yamamoto: Acid Catalysis in Organic Synthesis.

Author : M. Santelli,J.-M. Pons
Publisher : CRC Press
Page : 352 pages
File Size : 44,8 Mb
Release : 1995-11-21
Category : Science
ISBN : 0849378664

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Lewis Acids and Selectivity in Organic Synthesis by M. Santelli,J.-M. Pons Pdf

Lewis acids provide inexpensive access to elaborated molecules obtained with high selectivities (regio-, stereo-, and enantioselectivity). Lewis Acids and Selectivity in Organic Synthesis is the first book to deal with these new and promising roles of Lewis acids. The book begins with general considerations on Lewis acids and a description of Lewis acid-carbonyl complexes, which are involved in most of the reactions described: ene reactions, allylsilane and allyltin addition to carbonyl compounds, addition of nucleophiles to acetals, conjugated addition of allylsilanes and allyltins to unsaturated carbonyl compounds (Sakurai reaction), and Diels-Alder reaction. Subsequent chapters examine these issue in detail, with special attention given to the way Lewis acids induce diastereo- and enantioselectivity. The extensive use of schemes (approximately 1000) ensures rapid visual uptake of the information. Lewis Acids and Selectivity in Organic Synthesis serves as a valuable source of information for all who face the challenge of selectivity in organic synthesis.

Author : Dieter Schinzer
Publisher : Springer Science & Business Media
Page : 326 pages
File Size : 44,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400924642

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Selectivities in Lewis Acid Promoted Reactions by Dieter Schinzer Pdf

The ASI workshop on "Selectivities in Lewis Acid Promoted Reactions" held in the Emmantina-Hotel in Athens-Glyfada, Greece, October 2-7, 1988 was held to bring some light into the darkness of Lewis acid induced processes. As such the workshop reflects some current trends in organic synthesis, where Lewis acids are becoming a powerful tool in many different modern reactions, e.g. Diels-Alder reactions, Ene reactions, Sakurai reactions, and in general silicon and tin chemistry. The objective of this meeting was to bring together most of the world experts in the field to discuss the major reactions promoted by Lewis acids. Organic synthesis will play a major role in this book connected with some fundamental mechanistic work on allylsilane and -tin chemistry. Both natural product synthesis and unnatural molecules are presented in the chapters. The book presents all the 15 invited lectures and the contributions of 15 posters. I am confident that the material presented in this book will stimulate the chemistry, which has been discussed on our meeting, around the world. The meeting and the book were only possible through a grant of the NATO Scientific Affairs Devision and financial support by the following companies: Kali Chemie (Hannover, W-Germany), E. Merck (Darmstadt, W-Germany), Sandoz (Basel, Switzerland), Schering (Berlin, W-Germany).

Author : T. D. Beeson,Benjamin List
Publisher : Unknown
Page : 954 pages
File Size : 47,8 Mb
Release : 2012
Category : Asymmetric synthesis
ISBN : OCLC:793529680

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Asymmetric Organocatalysis by T. D. Beeson,Benjamin List Pdf

Author : J. Chris Slootweg,Andrew R. Jupp
Publisher : Springer Nature
Page : 404 pages
File Size : 40,9 Mb
Release : 2020-11-22
Category : Science
ISBN : 9783030588885

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Frustrated Lewis Pairs by J. Chris Slootweg,Andrew R. Jupp Pdf

This volume highlights the latest research in frustrated Lewis pair (FLP) chemistry and its applications. The contributions present the recent developments of the use of FLPs in asymmetric catalysis, polymer synthesis, homogeneous and heterogeneous catalysis, as well as demonstrating their use as a pedagogical tool. The book will be of interest to researchers in academia and industry alike.

Author : Mostafa Sayed,Zhi-Yong Han,Liu-Zhu Gong
Publisher : OAE Publishing Inc.
Page : 6 pages
File Size : 49,6 Mb
Release : 2023-04-20
Category : Science
ISBN : 8210379456XXX

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Pd-H/Lewis base cooperative catalysis confers asymmetric allylic alkylation of esters atom-economy and stereodivergence by Mostafa Sayed,Zhi-Yong Han,Liu-Zhu Gong Pdf

The construction of Csp3-Csp3 with high stereoselectivity, even in a stereodivergent way, has been a long-standing theme in organic synthesis. As an atom- and step-economic transformation, transition metal hydride-mediated allylic alkylation of enolizable carbonyl compounds with readily available allenes, alkynes or 1,3-dienes as the unconventional allylating reagents has recently emerged as a promising protocol for the stereoselective construction of Csp3-Csp3 bonds with high efficiency. Due to their less enolizability and weak nucleophilicity, simple esters remain challenging substrates for these coupling reactions. On the other hand, the strategy of metal/organo combined catalysis has recently emerged as one of the wide-ranging disciplines and powerful tools in asymmetric synthesis. Considering the recent achievements of chiral Lewis base catalysis in catalytic asymmetric α-functionalization of esters through a “rebound” mechanism, the cooperative combination of chiral Lewis bases and metal hydride catalysis may offer great opportunities to the aforementioned chemistry. Recently, the groups of Snaddon and Zi have made remarkable progresses in this area through palladium and chiral Lewis base cooperative catalysis.

Author : G. A. Molander
Publisher : Thieme
Page : 508 pages
File Size : 43,7 Mb
Release : 2020-05-22
Category : Science
ISBN : 9783132429833

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Science of Synthesis: Dual Catalysis in Organic Synthesis 2 by G. A. Molander Pdf

The field of dual catalysis has developed rapidly over the last decade, and these volumes define its impact on organic synthesis. The most important, basic concepts of synergistic, dual catalytic cycles are introduced, providing newcomers to the field with reliable information on this new approach to facilitating the synthesis of organic molecules. Background information and reliable procedures for challenging transformations in synthesis are presented, applying the concept of cooperative dual catalysis as a means of increasing molecular complexity in the most efficient manner. The most useful, practical, and reliable methods for dual catalysis combining metal catalysts, organocatalysts, photocatalysts, and biocatalysts are presented.

Author : Benjamin List,Keiji Maruoka
Publisher : Thieme Chemistry
Page : 954 pages
File Size : 53,7 Mb
Release : 2012
Category : Science
ISBN : 3131693614

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Asymmetric Organocatalysis by Benjamin List,Keiji Maruoka Pdf

Authoritative, broad overview of the field, compiled by 36 experts Critical presentation of the best organocatalytic and related methodologies available today for practical asymmetric synthesis Provides alternative, greener syntheses with simple and easily used catalysts helping avoid the use of expensive and/or toxic metals Asymmetric Organocatalysis 1 comprehensively covers all the catalysts and reactions within the activation modes Lewis base catalysis and Lewis acid catalysis. Typical or general experimental procedures as well as mechanistic, technical and theoretical aspects are included, allowing the reader to clearly see how simple, clean and efficient this chemistry is. This volume is part of a 2-volume set: Science of Synthesis Asymmetric Organocatalysis Workbench Edition Further information about Asymmetric Organocatalysis (including sample pages and the table of contents) General information about Science of Synthesis

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 55,8 Mb
Release : 2012
Category : Asymmetric synthesis
ISBN : OCLC:793529680

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Asymmetric Organocatalysis by Anonim Pdf

Author : René Peters
Publisher : John Wiley & Sons
Page : 456 pages
File Size : 46,5 Mb
Release : 2015-01-30
Category : Technology & Engineering
ISBN : 9783527681044

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Cooperative Catalysis by René Peters Pdf

Written by experts in the field, this is a much-needed overview of the rapidly emerging field of cooperative catalysis. The authors focus on the design and development of novel high-performance catalysts for applications in organic synthesis (particularly asymmetric synthesis), covering a broad range of topics, from the latest progress in Lewis acid / Brønsted base catalysis to e.g. metal-assisted organo catalysis, cooperative metal/enzyme catalysis, and cooperative catalysis in polymerization reactions and on solid surfaces. The chapters are classified according to the type of cooperating activating groups, and describe in detail the different strategies of cooperative activation, highlighting their respective advantages and pitfalls. As a result, readers will learn about the different concepts of cooperative catalysis, their corresponding modes of operation and their applications, thus helping to find a solution to a specific synthetic catalysis problem.

Author : R. A. Sheldon,Isabella Arends,Ulf Hanefeld
Publisher : John Wiley & Sons
Page : 448 pages
File Size : 45,8 Mb
Release : 2007-06-27
Category : Science
ISBN : 9783527611010

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Green Chemistry and Catalysis by R. A. Sheldon,Isabella Arends,Ulf Hanefeld Pdf

This first book to focus on catalytic processes from the viewpoint of green chemistry presents every important aspect: · Numerous catalytic reductions and oxidations methods · Solid-acid and solid-base catalysis · C-C bond formation reactions · Biocatalysis · Asymmetric catalysis · Novel reaction media like e.g. ionic liquids, supercritical CO2 · Renewable raw materials Written by Roger A. Sheldon -- without doubt one of the leaders in the field with much experience in academia and industry -- and his co-workers, the result is a unified whole, an indispensable source for every scientist looking to improve catalytic reactions, whether in the college or company lab.

Author : Michael E. Ford
Publisher : CRC Press
Page : 672 pages
File Size : 47,8 Mb
Release : 2000-10-18
Category : Science
ISBN : 9781482270754

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Catalysis of Organic Reactions by Michael E. Ford Pdf

This volume documents developments in the study of catalysis relating to organic synthesis and its application in industrial processes. It surveys a wide range of homo- and heterogeneous catalysis for industrial and pharmaceutical chemicals. It covers enantioselective hydrogenation, catalyzed hydrogens and oxidation, carbonylation, hydroaminomethyl