Life Cycle Decisions For Biomedical Data

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Life-Cycle Decisions for Biomedical Data

Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Division on Earth and Life Studies,Division on Engineering and Physical Sciences,Board on Research Data and Information,Board on Life Sciences,Computer Science and Telecommunications Board,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Committee on Forecasting Costs for Preserving and Promoting Access to Biomedical Data
Publisher : National Academies Press
Page : 185 pages
File Size : 51,6 Mb
Release : 2020-10-04
Category : Science
ISBN : 9780309670036

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Life-Cycle Decisions for Biomedical Data by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Division on Earth and Life Studies,Division on Engineering and Physical Sciences,Board on Research Data and Information,Board on Life Sciences,Computer Science and Telecommunications Board,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Committee on Forecasting Costs for Preserving and Promoting Access to Biomedical Data Pdf

Biomedical research results in the collection and storage of increasingly large and complex data sets. Preserving those data so that they are discoverable, accessible, and interpretable accelerates scientific discovery and improves health outcomes, but requires that researchers, data curators, and data archivists consider the long-term disposition of data and the costs of preserving, archiving, and promoting access to them. Life Cycle Decisions for Biomedical Data examines and assesses approaches and considerations for forecasting costs for preserving, archiving, and promoting access to biomedical research data. This report provides a comprehensive conceptual framework for cost-effective decision making that encourages data accessibility and reuse for researchers, data managers, data archivists, data scientists, and institutions that support platforms that enable biomedical research data preservation, discoverability, and use.

Planning for Long-Term Use of Biomedical Data

Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Board on Research Data and Information,Division on Earth and Life Studies,Board on Life Sciences,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics
Publisher : National Academies Press
Page : 93 pages
File Size : 47,6 Mb
Release : 2020-07-09
Category : Computers
ISBN : 9780309672757

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Planning for Long-Term Use of Biomedical Data by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Board on Research Data and Information,Division on Earth and Life Studies,Board on Life Sciences,Division on Engineering and Physical Sciences,Computer Science and Telecommunications Board,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics Pdf

Biomedical research data sets are becoming larger and more complex, and computing capabilities are expanding to enable transformative scientific results. The National Institutes of Health's (NIH's) National Library of Medicine (NLM) has the unique role of ensuring that biomedical research data are findable, accessible, interoperable, and reusable in an ethical manner. Tools that forecast the costs of long-term data preservation could be useful as the cost to curate and manage these data in meaningful ways continues to increase, as could stewardship to assess and maintain data that have future value. The National Academies of Sciences, Engineering, and Medicine convened a workshop on July 11-12, 2019 to gather insight and information in order to develop and demonstrate a framework for forecasting long-term costs for preserving, archiving, and accessing biomedical data. Presenters and attendees discussed tools and practices that NLM could use to help researchers and funders better integrate risk management practices and considerations into data preservation, archiving, and accessing decisions; methods to encourage NIH-funded researchers to consider, update, and track lifetime data; and burdens on the academic researchers and industry staff to implement these tools, methods, and practices. This publication summarizes the presentations and discussion of the workshop.

Sharing Clinical Trial Data

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Strategies for Responsible Sharing of Clinical Trial Data
Publisher : National Academies Press
Page : 304 pages
File Size : 41,8 Mb
Release : 2015-04-20
Category : Medical
ISBN : 9780309316323

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Sharing Clinical Trial Data by Institute of Medicine,Board on Health Sciences Policy,Committee on Strategies for Responsible Sharing of Clinical Trial Data Pdf

Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research--from funders, to researchers, to journals, to physicians, and ultimately, to patients.

Leveraging Biomedical and Healthcare Data

Author : Firas Kobeissy,Kevin Wang,Fadi A. Zaraket,Ali Alawieh
Publisher : Academic Press
Page : 225 pages
File Size : 50,8 Mb
Release : 2018-11-23
Category : Medical
ISBN : 9780128095614

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Leveraging Biomedical and Healthcare Data by Firas Kobeissy,Kevin Wang,Fadi A. Zaraket,Ali Alawieh Pdf

Leveraging Biomedical and Healthcare Data: Semantics, Analytics and Knowledge provides an overview of the approaches used in semantic systems biology, introduces novel areas of its application, and describes step-wise protocols for transforming heterogeneous data into useful knowledge that can influence healthcare and biomedical research. Given the astronomical increase in the number of published reports, papers, and datasets over the last few decades, the ability to curate this data has become a new field of biomedical and healthcare research. This book discusses big data text-based mining to better understand the molecular architecture of diseases and to guide health care decision. It will be a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in understanding more about how to process and apply great amounts of data to improve their research. Includes at each section resource pages containing a list of available curated raw and processed data that can be used by researchers in the field Provides demonstrative and relevant examples that serve as a general tutorial Presents a list of algorithm names and computational tools available for basic and clinical researchers

Principles of Biomedical Informatics

Author : Ira J. Kalet
Publisher : Academic Press
Page : 709 pages
File Size : 47,5 Mb
Release : 2013-09-26
Category : Business & Economics
ISBN : 9780123914620

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Principles of Biomedical Informatics by Ira J. Kalet Pdf

This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as:• tree structured data, interval trees, and time-oriented medical data and their use• On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics• a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system• X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing• an introduction to Markov processes, and• an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies. It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields. As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation. The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling. Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems

Sociological Abstracts

Author : Leo P. Chall
Publisher : Unknown
Page : 836 pages
File Size : 54,8 Mb
Release : 1997
Category : Sociology
ISBN : UOM:39015078349092

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Sociological Abstracts by Leo P. Chall Pdf

CSA Sociological Abstracts abstracts and indexes the international literature in sociology and related disciplines in the social and behavioral sciences. The database provides abstracts of journal articles and citations to book reviews drawn from over 1,800+ serials publications, and also provides abstracts of books, book chapters, dissertations, and conference papers.

Reproducibility and Replicability in Science

Author : National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Board on Research Data and Information,Division on Engineering and Physical Sciences,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Division of Behavioral and Social Sciences and Education,Committee on National Statistics,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Reproducibility and Replicability in Science
Publisher : National Academies Press
Page : 257 pages
File Size : 48,5 Mb
Release : 2019-10-20
Category : Science
ISBN : 9780309486163

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Reproducibility and Replicability in Science by National Academies of Sciences, Engineering, and Medicine,Policy and Global Affairs,Committee on Science, Engineering, Medicine, and Public Policy,Board on Research Data and Information,Division on Engineering and Physical Sciences,Committee on Applied and Theoretical Statistics,Board on Mathematical Sciences and Analytics,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Division of Behavioral and Social Sciences and Education,Committee on National Statistics,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Reproducibility and Replicability in Science Pdf

One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Health Informatics Meets EHealth

Author : G. Schreier,D. Hayn
Publisher : IOS Press
Page : 360 pages
File Size : 50,7 Mb
Release : 2018-05-18
Category : Medical
ISBN : 9781614998587

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Health Informatics Meets EHealth by G. Schreier,D. Hayn Pdf

Biomedical engineering and health informatics are closely related to each other, and it is often difficult to tell where one ends and the other begins, but ICT systems in healthcare and biomedical systems and devices are already becoming increasingly interconnected, and share the common entity of data. This is something which is set to become even more prevalent in future, and will complete the chain and flow of information from the sensor, via processing, to the actuator, which may be anyone or anything from a human healthcare professional to a robot. Methods for automating the processing of information, such as signal processing, machine learning, predictive analytics and decision support, are increasingly important for providing actionable information and supporting personalized and preventive healthcare protocols in both biomedical and digital healthcare systems and applications. This book of proceedings presents 50 papers from the 12th eHealth conference, eHealth2018, held in Vienna, Austria, in May 2018. The theme of this year’s conference is Biomedical Meets eHealth – From Sensors to Decisions, and the papers included here cover a wide range of topics from the field of eHealth. The book will be of interest to all those working to design and implement healthcare today.

Strategies in Biomedical Data Science

Author : Jay A. Etchings
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 40,6 Mb
Release : 2016-12-27
Category : Medical
ISBN : 9781119255970

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Strategies in Biomedical Data Science by Jay A. Etchings Pdf

An essential guide to healthcare data problems, sources, and solutions Strategies in Biomedical Data Science provides medical professionals with much-needed guidance toward managing the increasing deluge of healthcare data. Beginning with a look at our current top-down methodologies, this book demonstrates the ways in which both technological development and more effective use of current resources can better serve both patient and payer. The discussion explores the aggregation of disparate data sources, current analytics and toolsets, the growing necessity of smart bioinformatics, and more as data science and biomedical science grow increasingly intertwined. You'll dig into the unknown challenges that come along with every advance, and explore the ways in which healthcare data management and technology will inform medicine, politics, and research in the not-so-distant future. Real-world use cases and clear examples are featured throughout, and coverage of data sources, problems, and potential mitigations provides necessary insight for forward-looking healthcare professionals. Big Data has been a topic of discussion for some time, with much attention focused on problems and management issues surrounding truly staggering amounts of data. This book offers a lifeline through the tsunami of healthcare data, to help the medical community turn their data management problem into a solution. Consider the data challenges personalized medicine entails Explore the available advanced analytic resources and tools Learn how bioinformatics as a service is quickly becoming reality Examine the future of IOT and the deluge of personal device data The sheer amount of healthcare data being generated will only increase as both biomedical research and clinical practice trend toward individualized, patient-specific care. Strategies in Biomedical Data Science provides expert insight into the kind of robust data management that is becoming increasingly critical as healthcare evolves.

Data Analytics in Biomedical Engineering and Healthcare

Author : Kun Chang Lee,Sanjiban Sekhar Roy,Pijush Samui,Vijay Kumar
Publisher : Academic Press
Page : 298 pages
File Size : 47,8 Mb
Release : 2020-10-18
Category : Science
ISBN : 9780128193150

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Data Analytics in Biomedical Engineering and Healthcare by Kun Chang Lee,Sanjiban Sekhar Roy,Pijush Samui,Vijay Kumar Pdf

Data Analytics in Biomedical Engineering and Healthcare explores key applications using data analytics, machine learning, and deep learning in health sciences and biomedical data. The book is useful for those working with big data analytics in biomedical research, medical industries, and medical research scientists. The book covers health analytics, data science, and machine and deep learning applications for biomedical data, covering areas such as predictive health analysis, electronic health records, medical image analysis, computational drug discovery, and genome structure prediction using predictive modeling. Case studies demonstrate big data applications in healthcare using the MapReduce and Hadoop frameworks. Examines the development and application of data analytics applications in biomedical data Presents innovative classification and regression models for predicting various diseases Discusses genome structure prediction using predictive modeling Shows readers how to develop clinical decision support systems Shows researchers and specialists how to use hybrid learning for better medical diagnosis, including case studies of healthcare applications using the MapReduce and Hadoop frameworks

Biomedical Informatics

Author : Edward H. Shortliffe,James J. Cimino
Publisher : Springer Science & Business Media
Page : 970 pages
File Size : 50,9 Mb
Release : 2013-12-02
Category : Medical
ISBN : 9781447144748

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Biomedical Informatics by Edward H. Shortliffe,James J. Cimino Pdf

The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Fundamentals of Clinical Data Science

Author : Pieter Kubben,Michel Dumontier,Andre Dekker
Publisher : Springer
Page : 219 pages
File Size : 46,8 Mb
Release : 2018-12-21
Category : Medical
ISBN : 9783319997131

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Fundamentals of Clinical Data Science by Pieter Kubben,Michel Dumontier,Andre Dekker Pdf

This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.

Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering

Author : Ilker Ozsahin,Dilber Uzun Ozsahin,Berna Uzun
Publisher : Academic Press
Page : 334 pages
File Size : 52,8 Mb
Release : 2021-03-25
Category : Computers
ISBN : 9780128240878

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Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering by Ilker Ozsahin,Dilber Uzun Ozsahin,Berna Uzun Pdf

Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering contains several practical applications on how decision-making theory could be used in solving problems relating to the selection of best alternatives. The book focuses on assisting decision-makers (government, organizations, companies, general public, etc.) in making the best and most appropriate decision when confronted with multiple alternatives. The purpose of the analytical MCDM techniques is to support decision makers under uncertainty and conflicting criteria while making logical decisions. The knowledge of the alternatives of the real-life problems, properties of their parameters, and the priority given to the parameters have a great effect on consequences in decision-making. In this book, the application of MCDM has been provided for the real-life problems in health and biomedical engineering issues. Provides a comprehensive analysis and application multi-criteria decision-making methods Presents detail information about MCDM and their usage Covers state-of-the-art MCDM methods and offers applications of MCDM for health and biomedical engineering purposes

Enhancing the Vitality of the National Institutes of Health

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Organizational Structure of the National Institutes of Health
Publisher : National Academies Press
Page : 165 pages
File Size : 55,5 Mb
Release : 2003-08-29
Category : Medical
ISBN : 9780309089678

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Enhancing the Vitality of the National Institutes of Health by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Organizational Structure of the National Institutes of Health Pdf

The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.