Lipids In Diabetes Ecab

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Insulin Resistance - ECAB

Gita Ganguly Mukherjee

Author : Gita Ganguly Mukherjee
Publisher : Elsevier Health Sciences
Page : 147 pages
File Size : 45,6 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9788131232217

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Insulin Resistance - ECAB by Gita Ganguly Mukherjee Pdf

The insulin resistance syndrome can be defined as insulin resistance, compensatory hyperinsulinemia, and their associated co-morbidities. Clinically, the term insulin resistance syndrome describes a constellation of abnormalities such as obesity, hypertension, dyslipidemia, type 2 diabetes/hyperglycemia, and coronary artery disease. Insulin is responsible for glucose uptake into the body cells and tissues. The response of the cells to insulin varies from individual to individual. In some individuals, the tissue response to insulin may be diminished. This means that even with adequate levels of insulin, the glucose uptake into the cells and tissues is not optimal. This results in a compensatory over-secretion of insulin from the pancreas. The persistence of high levels of insulin in the blood or hyperinsulinemia is thought to be responsible for some of the abnormalities associated with this condition. However, the exact causal association of the condition with these disorders and the pathophysiology of their evolution are unclear. The most common underlying mechanism proposed is increased free fatty acids from abdominal fat in individuals with central obesity. This leads to deranged insulin signaling, reduced muscular glucose uptake, increased triglyceride synthesis, and hepatic gluconeogenesis. A genetic basis of the disease as well as several other factors such as tumor necrosis factor-α, adiponectin, leptin, Interleukin-6, and some adipokines have also been implicated. Insulin resistance syndrome is of clinical significance because of its association with potentially debilitating conditions that contribute to long-term morbidity and even mortality of the individual. People with insulin resistance syndrome are at an increased risk of developing type 2 diabetes, hypertension, dyslipidemia, myocardial infarction, polycystic ovarian disease, and fatty liver. In this book, we have tried to collate the experiences of the pioneers of this field on the subject and provide the reader a comprehensive view on the topic along with practical management points, which we are sure will benefit the physicians in their clinical practice. The contributors have focused on the condition as is prevalent in our subcontinent and have tried to give an insight on the issues pertaining to the same with a topical flavor.

Lipids in Diabetes - ECAB

S V Madhu

Author : S V Madhu
Publisher : Elsevier Health Sciences
Page : 134 pages
File Size : 40,9 Mb
Release : 2013-07-23
Category : Medical
ISBN : 9788131232132

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Lipids in Diabetes - ECAB by S V Madhu Pdf

Type 2 diabetes mellitus is associated with a greater risk of developing atherosclerotic macrovascular diseases like myocardial infarction, stroke, and peripheral vascular disease. There is 2- to 4-fold increased risk of atherosclerotic heart disease and stroke in diabetic patients compared to non-diabetic patients. As the prevalence of type 2 diabetes is increasing rapidly, this diabetes related atherosclerotic disease is predicted to be a major public health problem. Atherosclerosis is a complex process and in diabetic patients, it behaves differently with increased lesion progression and severity. This accelerated atherosclerotic process in diabetics is explained on the basis of several risk factors like hyperglycemia, dyslipidemia, accelerated formation of advanced glycation end products, increased oxidative stress, and genetic factors. It is difficult to establish precisely the elements responsible for this atherosclerosis in diabetics, but by epidemiological, clinical, and by animal studies, it has been possible to get an idea of this problem in diabetics. Of the several risk factors for atherosclerosis in diabetes, dyslipidemia is the leading one, and an insight into the pathophysiologic relation of isolated triglyceridemia in Indian diabetics with the identification of the targets for control of lipids in diabetes (practical vs. ideal) needs to be well understood by the treating physician. This book is designed to address such issues with supportive typical clinical scenarios, with which the readers will be able to identify. Thus, it provides an excellent opportunity to widen one’s perspective in this area.

Hotspots in Diabetes - ECAB

Ambady Ramachandran

Author : Ambady Ramachandran
Publisher : Elsevier Health Sciences
Page : 129 pages
File Size : 53,6 Mb
Release : 2013-07-12
Category : Medical
ISBN : 9788131232170

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Hotspots in Diabetes - ECAB by Ambady Ramachandran Pdf

Diabetes is one of the most important non-communicable lifestyle diseases. Diabetes is a multifaceted disorder which possibly influences and impacts body pathophysiology by different mechanisms and in varied ways. Diabetes has a very distinguished impact on cardiovascular system and plays a detrimental role in development of cardiovascular disorders. Metabolic memory is used to describe the impact of exposure to glucotoxicity, lipotoxicity and other metabolic disturbances, either as an adverse or a beneficial cell response which determines the later development of vascular complications. Terms such as metabolic imprint, legacy effect, glycemic memory or latent hyperglycemic damage are also used. Diabetes has significant impact on different facets of life. Diabetes has a distinguished but significant impact on development of various cancers. Diabetes has a positive, negative and even neutral impact on pathogenesis and progression of cancer depending upon the tumor site. On the contrary, cancer also has a significant effect on diabetes development and management. These facets tend to get overlooked in the study of diabetes development and management. All these aspects are being thoroughly covered in this project so as to facilitate better management of diabetics.

Critical Issues and Diabetes - ECAB - E-Book

Samar Banerjee

Author : Samar Banerjee
Publisher : Elsevier Health Sciences
Page : 124 pages
File Size : 51,5 Mb
Release : 2014-12-12
Category : Medical
ISBN : 9788131239247

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Critical Issues and Diabetes - ECAB - E-Book by Samar Banerjee Pdf

Critical Issues and Diabetes - ECAB - E-Book

Unconventional Organ Damage in Diabetes - ECAB

Samar Banerjee

Author : Samar Banerjee
Publisher : Elsevier Health Sciences
Page : 112 pages
File Size : 45,7 Mb
Release : 2012-09-14
Category : Medical
ISBN : 9788131232149

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Unconventional Organ Damage in Diabetes - ECAB by Samar Banerjee Pdf

Cell health depends on a steady supply of fuel from glucose and free fatty acids. Both these major fuels are regulated by insulin. Cells in the muscle, liver, and fat need insulin to receive glucose, and hence do not become exposed to high blood glucose levels when the blood sugars are high and insulin levels are low. The lack of insulin slows the movement of glucose into these cells, and probably spares them from damage when blood sugars are high. However, other cells such as those in the brain, nervous system, heart, blood vessels and kidneys pick up glucose directly from the blood without using insulin. These cells, except the brain, are more prone to damage from high blood sugars because they become exposed to high internal levels of glucose. This to quite an extent explains why damage tends to occur in specific organs such as in nerve and kidney cells, and in small blood vessels like those in the eyes. This project on the organ damage in diabetes is an attempt to elaborate on the various factors to be considered in managing these patients, the pointers for early diagnosis and prevention of the same.

Diabetes and Lifestyle - ECAB

Samar Banerjee

Author : Samar Banerjee
Publisher : Elsevier Health Sciences
Page : 124 pages
File Size : 49,5 Mb
Release : 2013-07-12
Category : Medical
ISBN : 9788131232200

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Diabetes and Lifestyle - ECAB by Samar Banerjee Pdf

Diabetes management, outcomes and prognosis are majorly affected by the lifestyle exercised by the diabetics. Diabetes has significant impact on the different facets of life. These facets tend to get overlooked in the management. The inter-relation of diabetes and marriage, sleep, travel, commute and uneven working hours seem to be trivial part of managing diabetes but are extremely important for a perfect recovery and management of the patient. Patients travelling with diabetes need to consider how to adapt their treatment programs to unfamiliar foods, irregular schedules, and varying amounts of exercise. Diabetes will be involved at every step of married life including vacations, outings, going to the movies, as well as intimate moments. Sleep and diabetes are interconnected. Sleep disorders have a slight but significant impact on diabetes management and it should be focused while attending a diabetic with sleep disorders. Shift workers make a special segment of diabetics, whose glucose monitoring and control need to be tailored in a special manner. With change in circadian rhythm and sleep pattern, diabetes management needs to be adjudged and adjusted. The main risks that arise in driving from having diabetes are hypoglycemia and the long term complications. All these aspects are being thoroughly covered in this book so as to facilitate better management of diabetes.

Microvascular Complications of Diabetes - ECAB

V Seshiah

Author : V Seshiah
Publisher : Elsevier Health Sciences
Page : 187 pages
File Size : 54,6 Mb
Release : 2009-09-15
Category : Medical
ISBN : 9788131232125

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Microvascular Complications of Diabetes - ECAB by V Seshiah Pdf

The pathogenesis of microvascular complications is complex and multifactorial. Yet, hyperglycemia emerges as the most important single cause, which has been proved by the Diabetes Control and Complications Trial (DCCT). Thus, the importance of protecting the body from hyperglycemia cannot be overstated; the direct and indirect effects on the human vascular tree are the major source of morbidity and mortality in both type 1 and type 2 diabetes. Generally, the injurious effects of hyperglycemia are separated into macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke) and microvascular complications (diabetic nephropathy, neuropathy, and retinopathy). It is important for physicians to understand the relationship between diabetes and vascular disease because the prevalence of diabetes continues to increase in our country, and the clinical requirements for primary and secondary prevention of these complications are also expanding.

Diabetes in Pregnancy - ECAB

Samar Banerjee

Author : Samar Banerjee
Publisher : Elsevier Health Sciences
Page : 132 pages
File Size : 51,5 Mb
Release : 2012-06-07
Category : Medical
ISBN : 9788131232521

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Diabetes in Pregnancy - ECAB by Samar Banerjee Pdf

Gestational diabetes mellitus (GDM) is classically seen in about 5–8% of the pregnant women. The condition appears to be caused by the same broad spectrum of physiological and genetic peculiarities that characterize diabetes outside of pregnancy. These women with GDM are also otherwise at high risk of having or developing diabetes even when not pregnant. The controversies regarding the diagnosis, management, and prevention of diabetes in pregnancy pose specific problems in clinical practice such as how to clinch the diagnosis, when to introduce therapy, what therapy to introduce, and how to predict the future course of the condition. This book is designed to address such questions with supportive typical clinical scenarios, with which all readers will be able to identify. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Insulins in Diabetes - ECAB

Rangasamy V. Jayakumar

Author : Rangasamy V. Jayakumar
Publisher : Elsevier Health Sciences
Page : 122 pages
File Size : 50,9 Mb
Release : 2012-07-05
Category : Medical
ISBN : 9788131232071

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Insulins in Diabetes - ECAB by Rangasamy V. Jayakumar Pdf

Decision making in instituting insulin therapy is an important aspect of diabetes management. The appropriate insulin regimen for an individual patient should take into account the patient’s lifestyle, age, motivation, general health, self-management skills, and treatment goals. In addition, a discussion of the newer insulins versus older insulin is a much desired topic in the Indian context. Another area of interest is the insulin delivery mechanism in the intensive care units in hospital settings. This CME module is designed to address such questions with supportive typical clinical scenarios, with which all readers will be able to identify. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Infections in Diabetes - ECAB

Samar Banerjee

Author : Samar Banerjee
Publisher : Elsevier Health Sciences
Page : 110 pages
File Size : 50,9 Mb
Release : 2012-07-05
Category : Medical
ISBN : 9788131232064

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Infections in Diabetes - ECAB by Samar Banerjee Pdf

Patients with diabetes are predisposed to infections. The risk ratio for infectious disease-related hospitalization for diabetic versus nondiabetic persons is more than 2, and almost 2 for death attributable to infection. Infections in diabetes may precipitate metabolic derangements and, conversely, the metabolic derangements of diabetes may facilitate infection. Abnormalities in the microvascular circulation of individuals with diabetes may result in decreased tissue perfusion, which facilitates the acquisition of infection and impairs response to therapy. The incidence of TB among diabetic patients is 2–5 times higher when compared to the general population, which recently has raised the concern that a combination of DM and HIV infection might lead to a further increased incidence of TB in India and in other developing nations. However, it is unclear whether diabetes is an independent risk for common upper and lower respiratory tract infections. Urinary tract is also reported to be the most prevalent site of infection in patients with diabetes. These infections are known to account for a relatively smaller percentage of reported patients probably due to the fact that most patients, including diabetics, with urinary tract infection are treated as outpatients. A number of long-term effects of diabetes mellitus on the genitourinary system predispose diabetic patients to bacterial urinary tract infections. In addition, complications of urinary tract infection (e.g., bacteremia, renal abscesses, and renal papillary necrosis) are more common in patients with than without diabetes. Rhinocerebral mucormycosis and emphysematous pyelonephritis are some of the less commonly reported conditions seen in diabetics though being important pathologies. The primary goal of this book is to provide a high-quality, evidence-based text on the various aspects of the associations of various infections in diabetics with prime focus on TB and diabetes, rare conditions such as rhinocerebral mucormycosis and emphysematous pyelonephritis and also the various acute infections commonly reported in the condition. The book includes in-depth analysis of the diagnostic and management issues considering the same.

Dietary Considerations in Diabetes - ECAB

Anoop Misra

Author : Anoop Misra
Publisher : Elsevier Health Sciences
Page : 111 pages
File Size : 50,8 Mb
Release : 2012-07-05
Category : Medical
ISBN : 9788131232095

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Dietary Considerations in Diabetes - ECAB by Anoop Misra Pdf

Diet plays an important role in the treatment of diabetes, alone or in combination with insulin or oral hypoglycemic drugs. The diabetic nutrition plan of an individual necessitates to be based upon, excepting the usual parameters, his/her socioeconomic status, ethnicity/religion, and local food habits. It is important that diet plan is individualized and also region based. Since there are a number of artificial sweeteners available now, it is necessary that physicians should take in account scientific data while prescribing any artificial sweetener. This issue in the ECAB Update Series: Diabetology reviews these issues in accordance with the Indian Dietary habits and available evidence to support the clinical decisions.

Diabetic Kidney Disease - ECAB

K V Dakshinamurty

Author : K V Dakshinamurty
Publisher : Elsevier Health Sciences
Page : 223 pages
File Size : 40,7 Mb
Release : 2013-07-22
Category : Medical
ISBN : 9788131232026

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Diabetic Kidney Disease - ECAB by K V Dakshinamurty Pdf

The prevalence of Diabetes Mellitus is increasing rapidly all over the world and more so in the developing countries. The global burden of diabetes is expected to double between 2000 and 2030, with the greatest increases in prevalence occurring in the Middle East, sub-Saharan Africa and India. Moreover, the development of type 2 diabetes during the childbearing years is also likely to increase, primarily in the developing countries. It has already been established that Diabetes is the most common primary cause leading to end stage renal disease (ESRD) and Diabetic Nephropathy is the leading cause of chronic kidney disease (CKD) in India. The cornerstones of management of Diabetic Kidney Diseases include early diagnosis of diabetic nephropathy, prevention of its progression and treatment of the co-morbid conditions. Substantial under-diagnosis of both diabetes and chronic kidney disease leads to lost opportunities for prevention. An inadequate or inappropriate care of patients with diabetic kidney disease contributes to disease progression eventually up to a stage that requires renal replacement therapy, which is not a feasible option for many on a long-term basis, especially in a developing country like ours. This book covers various aspects of diabetic kidney disease in detail and attempts to familiarize the reader with the existing aspects of the conditions as well as touch upon the new advances in the field. The first chapter outlines the extent to which the condition affects the population globally as well as in our country. The second chapter explores the underlying mechanism by which the disease starts and progresses and the pathological markers of the same. The third chapter delineates the clinical and diagnostic markers of the condition. The fourth and fifth chapters speak of the non-diabetic glomerular and non-glomerular diseases in diabetics. The sixth chapter addresses the most important and desirable goal of preventing the progression and ideally the onset of the disease. The seventh chapter puts together the various treatment modalities available and the subsequent chapter explores the management options for cases requiring renal replacement. In addition to the emphasis to Indian literature at the end of each chapter, the ninth chapter is specially included to highlight the salient aspects of this condition from the Indian perspective. This book will be beneficial not only for the nephrologists, but also for the epidemiologists, medical students, diabetologists and every doctor who deals with diabetes mellitus.

Cardiometabolic Risk in India - ECAB

KM Prasanna Kumar

Author : KM Prasanna Kumar
Publisher : Elsevier Health Sciences
Page : 120 pages
File Size : 48,6 Mb
Release : 2009-02-15
Category : Medical
ISBN : 9788131232101

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Cardiometabolic Risk in India - ECAB by KM Prasanna Kumar Pdf

Cardiometabolic disease is the leading cause of death in many parts of the world. There are many potentially modifiable and non-modifiable risk factors associated with the same. Although with the recent advances in management and preventive strategies the mortality rates have reduced, but no patient actually achieves an adequate control of the CVD risk factors with the declining quality of life. In addition, growing obesity and DM in younger age groups has further undermined the improvements achieved in CVD. Diabetes and CVD share a "common soil" in their etiology and the causative factors for these diseases are termed as "cardiometabolic risk factors." Cardiometabolic risk (CMR) is the global risk of developing type 2 diabetes and CVD. CMR factors include overweight or obesity, high blood glucose, HTN, dyslipidemia, inflammation and hypercoagulation, physical inactivity, smoking, age, race and ethnicity, gender, and family history. Among these, age, race/ethnicity, gender, and family history are non-modifiable risk factors. The remaining are modifiable risk factors and closely interrelated. Recently, systematic prospective studies have shown evidences that moderate lifestyle modifications help in reducing the metabolic risk factors. The major principles include cessation of smoking, enhanced physical activity, and reduction of excess weight. Healthy diet also has a major role in controlling overweight and maintaining ideal weight. Each of the risk factors poses a danger to good health; the propensity increases with multiple risk factors. It is also shown that the CMR factors tend to cluster as the metabolic syndrome. This book is designed to address such questions with supportive typical clinical scenarios, with which all readers will be able to identify. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Recent Advances in Metabolic Syndrome – I - ECAB

R R Kasliwal,Anoop Misra

Author : R R Kasliwal,Anoop Misra
Publisher : Elsevier Health Sciences
Page : 207 pages
File Size : 49,7 Mb
Release : 2012-06-08
Category : Medical
ISBN : 9788131232187

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Recent Advances in Metabolic Syndrome – I - ECAB by R R Kasliwal,Anoop Misra Pdf

India in particular and South-Asia in general have witnessed a rapid increase in the prevalence and incidence of cardiovascular disease over the past 25 years. Lifestyles changes, unhealthy diet, lack of regular physical exercise, and obesity have all led to rising prevalence of metabolic syndrome. It is of no wonder that metabolic syndrome is being increasingly recognized as a clinical entity which is believed to be associated with increased risk of cardiovascular disease beyond individual risk factors, though this is at times debated. This monograph addresses the total nuance of metabolic syndrome in its entirety and answers questions frequently asked on this subject. The authors are internationally respected investigators in their own right having made major contributions in the particular field and are revered teachers as well. The book itself has clear sections which makes it very user friendly and divided into two volumes. The first volume has the evaluation of metabolic syndrome and the vastness of the problem and how it leads to smouldering dysfunctional endothelium making such a patient vulnerable to vascular disease. It purely deals with clinical issues we face daily in metabolic syndrome and patients. It is fairly broad-based to answer most of the queries which arise in a busy clinician’s head while dealing with metabolic syndrome on a day-to-day basis. Of special interest are chapters on metabolic syndrome in children, non-alcoholic fatty liver disease and hypogonadism.

ECAB Non-alcoholic Fatty Liver Disease - E-Book

Gourdas Choudhuri

Author : Gourdas Choudhuri
Publisher : Elsevier Health Sciences
Page : 102 pages
File Size : 49,9 Mb
Release : 2014-12-11
Category : Medical
ISBN : 9788131239599

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ECAB Non-alcoholic Fatty Liver Disease - E-Book by Gourdas Choudhuri Pdf

ECAB Non-alcoholic Fatty Liver Disease - E-Book

Lipids In Diabetes Ecab

Insulin Resistance - ECAB by Gita Ganguly Mukherjee Pdf

Lipids in Diabetes - ECAB by S V Madhu Pdf

Hotspots in Diabetes - ECAB by Ambady Ramachandran Pdf

Critical Issues and Diabetes - ECAB - E-Book by Samar Banerjee Pdf

Unconventional Organ Damage in Diabetes - ECAB by Samar Banerjee Pdf

Diabetes and Lifestyle - ECAB by Samar Banerjee Pdf

Microvascular Complications of Diabetes - ECAB by V Seshiah Pdf

Diabetes in Pregnancy - ECAB by Samar Banerjee Pdf

Insulins in Diabetes - ECAB by Rangasamy V. Jayakumar Pdf

Infections in Diabetes - ECAB by Samar Banerjee Pdf

Dietary Considerations in Diabetes - ECAB by Anoop Misra Pdf

Diabetic Kidney Disease - ECAB by K V Dakshinamurty Pdf

Cardiometabolic Risk in India - ECAB by KM Prasanna Kumar Pdf

Recent Advances in Metabolic Syndrome – I - ECAB by R R Kasliwal,Anoop Misra Pdf

ECAB Non-alcoholic Fatty Liver Disease - E-Book by Gourdas Choudhuri Pdf

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