Diabetic Kidney Disease Ecab

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Diabetic Kidney Disease - ECAB

Author : K V Dakshinamurty
Publisher : Elsevier Health Sciences
Page : 223 pages
File Size : 47,9 Mb
Release : 2013-07-22
Category : Medical
ISBN : 9788131232026

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Diabetic Kidney Disease - ECAB by K V Dakshinamurty Pdf

The prevalence of Diabetes Mellitus is increasing rapidly all over the world and more so in the developing countries. The global burden of diabetes is expected to double between 2000 and 2030, with the greatest increases in prevalence occurring in the Middle East, sub-Saharan Africa and India. Moreover, the development of type 2 diabetes during the childbearing years is also likely to increase, primarily in the developing countries. It has already been established that Diabetes is the most common primary cause leading to end stage renal disease (ESRD) and Diabetic Nephropathy is the leading cause of chronic kidney disease (CKD) in India. The cornerstones of management of Diabetic Kidney Diseases include early diagnosis of diabetic nephropathy, prevention of its progression and treatment of the co-morbid conditions. Substantial under-diagnosis of both diabetes and chronic kidney disease leads to lost opportunities for prevention. An inadequate or inappropriate care of patients with diabetic kidney disease contributes to disease progression eventually up to a stage that requires renal replacement therapy, which is not a feasible option for many on a long-term basis, especially in a developing country like ours. This book covers various aspects of diabetic kidney disease in detail and attempts to familiarize the reader with the existing aspects of the conditions as well as touch upon the new advances in the field. The first chapter outlines the extent to which the condition affects the population globally as well as in our country. The second chapter explores the underlying mechanism by which the disease starts and progresses and the pathological markers of the same. The third chapter delineates the clinical and diagnostic markers of the condition. The fourth and fifth chapters speak of the non-diabetic glomerular and non-glomerular diseases in diabetics. The sixth chapter addresses the most important and desirable goal of preventing the progression and ideally the onset of the disease. The seventh chapter puts together the various treatment modalities available and the subsequent chapter explores the management options for cases requiring renal replacement. In addition to the emphasis to Indian literature at the end of each chapter, the ninth chapter is specially included to highlight the salient aspects of this condition from the Indian perspective. This book will be beneficial not only for the nephrologists, but also for the epidemiologists, medical students, diabetologists and every doctor who deals with diabetes mellitus.

Pregnancy and Kidney Disease - ECAB

Author : Vijay Kher
Publisher : Elsevier Health Sciences
Page : 148 pages
File Size : 51,6 Mb
Release : 2012-07-26
Category : Medical
ISBN : 9788131231968

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Pregnancy and Kidney Disease - ECAB by Vijay Kher Pdf

There are certain structural and functional changes that develop in the urinary tract during normal regnancy, which are significantly different than non-pregnant normal females. During pregnancy in women with underlying chronic kidney disease (CKD), the adaptation to these changes may not be optimal. Under these circumstances, the pregnancy outcome as well as maternal CKD may be affected. The issue focuses on the physiological changes in the kidney and assessment of proteinuria and GFR during pregnancy. The current update also details the cases of pregnancy in the setting of CKD describing the effect of CKD on pregnancy as well as effect of pregnancy on CKD. The chapter on pregnancy-induced hypertension―Pre-eclampsia focuses on the prevention and management of complications in the patient. The authors also give an insight into the pregnancy in cases after kidney transplantation.

Hypertension and Kidney Disease - ECAB

Author : Suresh C Tiwari
Publisher : Elsevier Health Sciences
Page : 162 pages
File Size : 40,7 Mb
Release : 2012-07-26
Category : Medical
ISBN : 9788131231975

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Hypertension and Kidney Disease - ECAB by Suresh C Tiwari Pdf

Hypertension is fast becoming a pandemic of enormous proportions, and its sequelae of cardiovascular and cerebrovascular adverse events is making it a leading cause of morbidity and mortality worldwide. The interrelationship of hypertension and kidney changes though established for quite some time, the exact mechanisms and causality are still being discovered. The role of kidney as evidenced by subtle changes in the initiation of ‘primary hypertension’ is increasingly being scrutinized. The effects of established renal causes that induce hypertension such as renal artery stenosis are well established. Pediatric population is also no longer immune to this potentially debilitating condition. This book will help the readers to: Understand the intricacies of the genesis of hypertension and its effects on the kidney Explore the various established guidelines and newer promising aspects in diagnosis and management of hypertension and the kidney changes Know the newer emerging concepts in the treatment of hypertension in the pediatric population Enlighten them about the benefits of timely management of the condition to prevent its progression to end-stage kidney disease, which requires expensive and invasive interventions not suitable to majority of population in a developing country like ours. This book aims to guide the practitioner to diagnose and manage hypertension in the setting of suspected, diagnosed, or established kidney disease with special reference to practical experience in India.

Kidney Disease and Nutrition - ECAB

Author : Bharat V Shah
Publisher : Elsevier Health Sciences
Page : 157 pages
File Size : 54,8 Mb
Release : 2013-05-28
Category : Medical
ISBN : 9788131232040

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Kidney Disease and Nutrition - ECAB by Bharat V Shah Pdf

Optimal nutrition is essential for maintaining the structural and functional integrity of all the organs and systems in the body. This is especially relevant in disease and dysfunctional states when the functioning of organ systems is compromised. This clinical update handbook aims to discuss and debate the impact of nutrition, describe methods for assessment of nutritional status and recommend the diet modifications helpful in managing various types of kidney diseases and dysfunctions. The first chapter of this book describes the various components of a healthy diet when there is no kidney disease or dysfunction. The chapter 2, 3, 4, and 5 provide a brief but relevant review of the dietary modifications and restrictions recommended in diabetic nephropathy, hypertensive nephropathy, renal stone disease, and nephrotic syndrome respectively. The two subsequent chapters 6 and 7 speak of the nutritional modifications indicated in management of acute injury of kidney and chronic kidney disease. The 8 and 9 chapters describe the dietary modifications that are compatible with the two types of dialysis, hemodialysis and peritoneal dialysis. The final chapter of the book describes the dietary recommendations and restrictions applicable before and after kidney transplantation. This book will help the readers understand the intricacies of the aspects mentioned above and guide the practitioner to diagnose and manage the nutritional aspect of various kidney diseases with special reference to practical experience in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of primary glomerular diseases by practitioners and students across the specialty.

End Stage Renal Disease - ECAB

Author : Ravi Raju Tatapudi
Publisher : Elsevier Health Sciences
Page : 205 pages
File Size : 52,8 Mb
Release : 2013-07-16
Category : Medical
ISBN : 9788131232019

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End Stage Renal Disease - ECAB by Ravi Raju Tatapudi Pdf

With the increase in lifestyle-related diseases like diabetes and hypertension the prevalence of Chronic Kidney Disease (CKD) is increasing exponentially and with it is increasing the burden of its ominous consequence, End Stage Renal Disease (ESRD). While ESRD is no longer a death sentence with the advent of efficient renal replacement therapies and the success of renal transplantation, factors such as high cost of these procedures, limited availability of donated kidneys and not enough number of centers equipped with these facilities puts the effective management of ESRD beyond the reach of an average person many-a-times. Additionally the presence of co-existing diseases that contribute to and sometimes complicate the renal impairment as well as delayed referral of the patients to nephrologists also makes matters worse. ESRD is not just a medical but also a social and economic condition that devastates the person and his/her entire family. Hence, early detection and effective prevention of progression of CKD in early stages to advanced CKD and ESRD is the call of the day. In fact, understanding the pathophysiology of the condition and adopting methods of primordial prevention in populations at risk may be desirable to ensure reduction in the incidence of CKD. In those with established CKD, a proactive approach to manage the disease manifestations and limit the ravages of other comorbidities is desirable. For those in advanced stages of CKD, the institution of an appropriate renal replacement therapy individually suited to the patient keeping in view the medical status, lifestyle requirements, economic viability and social acceptability should be advised. This book will help the reader understand the intricacies of the aspects mentioned above and guide the practitioner to diagnose and manage End Stage Renal Disease with special reference to practical experience of the same in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of the same by practitioners and students across the specialty.

Systemic Diseases & Renal Manifestations - ECAB

Author : D S Rana
Publisher : Elsevier Health Sciences
Page : 158 pages
File Size : 44,6 Mb
Release : 2012-06-13
Category : Medical
ISBN : 9788131231951

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Systemic Diseases & Renal Manifestations - ECAB by D S Rana Pdf

This book discusses the epidemiology, recognition, screening, and management of the various common systemic diseases that commonly present with renal manifestations like diabetic nephropathy, lupus nephritis, hypertension and renal involvement, liver disease, and dysproteinemias. Diabetic nephropathy remains the leading cause of end-stage renal disease across the world. The outlook for patients who have lupus nephritis has improved in the last decade. Kidney disease is common in patients who have advanced liver disease, and creatinine-based methods do not provide an accurate estimation of renal function in this population. Dysproteinemias are associated with protean renal manifestations, and renal disease may be the presenting manifestation. The authors have given a very comprehensive view pertaining to each topic and have given an insight to their own clinical experiences along with the standard guidelines as followed.

Polycystic Kidney Disease - ECAB

Author : K V Dakshinamurty
Publisher : Elsevier Health Sciences
Page : 262 pages
File Size : 41,9 Mb
Release : 2012-06-15
Category : Medical
ISBN : 9788131231999

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Polycystic Kidney Disease - ECAB by K V Dakshinamurty Pdf

Renal cystic diseases include a large number of sporadic and genetically determined congenital, developmental, or acquired conditions. A cyst is a cavity lined by epithelium and filled with fluid. Cysts derive primarily from tubules (from Bowman’s capsule to the collecting duct). Cystic kidneys of different etiologies may appear morphologically similar, whereas the same etiologic entity may cause a wide spectrum of renal abnormalities. Simple renal cysts are acquired and are not associated with any disease. In contrast, polycystic kidney diseases can be complicated by renal failure or tumor development. Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal single-gene disorder. Its prevalence at birth is between 1:400 and 1:1,000. It may progress to end stage renal disease by age 60 with 4.4% of patients requiring renal replacement therapy (dialysis or transplant) have ADPKD. The book is a comprehensive guide to diagnosis and management of the condition with special reference and experience around the same in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of the same by practitioners and students across the specialty.

Microvascular Complications of Diabetes - ECAB

Author : V Seshiah
Publisher : Elsevier Health Sciences
Page : 147 pages
File Size : 46,5 Mb
Release : 2009-09-15
Category : Medical
ISBN : 9788131232125

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Microvascular Complications of Diabetes - ECAB by V Seshiah Pdf

The pathogenesis of microvascular complications is complex and multifactorial. Yet, hyperglycemia emerges as the most important single cause, which has been proved by the Diabetes Control and Complications Trial (DCCT). Thus, the importance of protecting the body from hyperglycemia cannot be overstated; the direct and indirect effects on the human vascular tree are the major source of morbidity and mortality in both type 1 and type 2 diabetes. Generally, the injurious effects of hyperglycemia are separated into macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke) and microvascular complications (diabetic nephropathy, neuropathy, and retinopathy). It is important for physicians to understand the relationship between diabetes and vascular disease because the prevalence of diabetes continues to increase in our country, and the clinical requirements for primary and secondary prevention of these complications are also expanding.

Lipids in Diabetes - ECAB

Author : S V Madhu
Publisher : Elsevier Health Sciences
Page : 134 pages
File Size : 42,6 Mb
Release : 2013-07-23
Category : Medical
ISBN : 9788131232132

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Lipids in Diabetes - ECAB by S V Madhu Pdf

Type 2 diabetes mellitus is associated with a greater risk of developing atherosclerotic macrovascular diseases like myocardial infarction, stroke, and peripheral vascular disease. There is 2- to 4-fold increased risk of atherosclerotic heart disease and stroke in diabetic patients compared to non-diabetic patients. As the prevalence of type 2 diabetes is increasing rapidly, this diabetes related atherosclerotic disease is predicted to be a major public health problem. Atherosclerosis is a complex process and in diabetic patients, it behaves differently with increased lesion progression and severity. This accelerated atherosclerotic process in diabetics is explained on the basis of several risk factors like hyperglycemia, dyslipidemia, accelerated formation of advanced glycation end products, increased oxidative stress, and genetic factors. It is difficult to establish precisely the elements responsible for this atherosclerosis in diabetics, but by epidemiological, clinical, and by animal studies, it has been possible to get an idea of this problem in diabetics. Of the several risk factors for atherosclerosis in diabetes, dyslipidemia is the leading one, and an insight into the pathophysiologic relation of isolated triglyceridemia in Indian diabetics with the identification of the targets for control of lipids in diabetes (practical vs. ideal) needs to be well understood by the treating physician. This book is designed to address such issues with supportive typical clinical scenarios, with which the readers will be able to identify. Thus, it provides an excellent opportunity to widen one’s perspective in this area.

Primary Glomerular Diseases - ECAB

Author : Ramadas Pisharody
Publisher : Elsevier Health Sciences
Page : 166 pages
File Size : 45,9 Mb
Release : 2013-07-12
Category : Medical
ISBN : 9788131232057

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Primary Glomerular Diseases - ECAB by Ramadas Pisharody Pdf

The basic functional unit of kidney is the glomerulus. Any renal derangement at that level can lead to a multitude of diseases. The renal as well as glomerular disorders secondary to other causes such as hypertension, diabetes, other vasculites, drugs, malignancies, etc. have been adequately addressed. However, the primary glomerular disorders, due to an ambiguity regarding their genesis, have yet to be explored properly. Though these diseases are clubbed under the common head of "primary", they consist of various distinct subtypes with markedly different mechanisms of pathogenesis, course of the disease, response to treatment and prognoses. This clinical update explores the various types of pimary glomerular diseases with an aim to enhance the reader’s knowledge and aid in timely recognition and precise diagnosis of glomerular diseases to help chart the appropriate treatment of each individual condition. The first chapter elucidates the clinicopathological correlation of primary glomerular diseases to help differentiate them from each other and from other similar differential diagnoses without resorting to renal biopsy in all the cases. The second, third and fourth, chapters explore the various aspects of Proliferative Glomerulonephritis, Idiopathic Nephrotic Syndrome and Heredofamilial Glomerular Diseases. The last chapter summarizes the clinically relevant current perspectives regarding the pathogenesis and treatment modalities of all the primary glomerular diseases. This book will help the readers understand the intricacies of the aspects mentioned above and guide the practitioner to diagnose and manage Primary Glomerular Diseases with special reference to practical experience in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of primary glomerular diseases by practitioners and students across the specialty.

Practical Guide to Managing Hypertension - ECAB

Author : S S Iyengar,R R Kasliwal
Publisher : Elsevier Health Sciences
Page : 188 pages
File Size : 53,8 Mb
Release : 2012-06-08
Category : Medical
ISBN : 9788131231784

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Practical Guide to Managing Hypertension - ECAB by S S Iyengar,R R Kasliwal Pdf

This book is an effort by the author panel to address hypertension issues in a more comprehensive manner and present to practitioners as a ready reference. It covers different practical aspects related to hypertension like the burden of hypertension in India, its complications and comorbidities, its awareness and early detection, appropriate treatment, and achieving the therapeutic targets. Hypertension can be easily detectable, eminently treatable, and there are safe and effective drugs. But in India, there has been a huge lack of awareness of the condition especially urban-rural bias, and thus, it results in inadequate treatment. The prevalence of hypertension in India, in the urban areas, varies from 11% to 31% amongst men and 13% to 34% amongst women. In rural areas, the same amounts to about 1–4% and 3–5%. This publication covers the major global and Indian hypertension management guidelines and tries to sincerely put forth this compilation which will address the most important and frequently asked questions in approach to diagnosis and management of hypertension in day-to-day practice and will effectively bridge the gap between guidelines and practice. Application of global hypertension management guidelines like JNC VII in Indian Clinical Scenario Highlighting the compliance issues in hypertension management Focusing on the screening and the right treatment goals of hypertension On the management aspect, the publication provides a holistic management approach covering drugs, diet, and lifestyle changes

Oxidative Stress Modulators and Functional Foods

Author : Junsei Taira
Publisher : MDPI
Page : 244 pages
File Size : 53,7 Mb
Release : 2021-08-30
Category : Medical
ISBN : 9783036509389

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Oxidative Stress Modulators and Functional Foods by Junsei Taira Pdf

This book “Oxidative Stress Modulators and Functional Foods” is focused on the antioxidant role of natural products, involving their ability to modulate oxidative stress and/or reverse disease studied both in vitro and in animal models. Additionally, the molecular mechanisms of these actions and the modulation of signalling pathways related to inflammation, apoptosis, and survival response in the redox system by natural products are included.

Microvascular Disorders In Diabetes

Author : Seshiah
Publisher : Elsevier Health Sciences
Page : 147 pages
File Size : 48,6 Mb
Release : 2009
Category : Electronic
ISBN : 9788131221723

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Microvascular Disorders In Diabetes by Seshiah Pdf