Liver Cirrhosis From Pathophysiology To Disease Management

Author : J. Bosch,Andrew Burroughs,F. Lammert,D. Lebrec,Tilman Sauerbruch
Publisher : Springer
Page : 0 pages
File Size : 41,8 Mb
Release : 2008-05-29
Category : Medical
ISBN : 1402086555

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Liver Cirrhosis: From Pathophysiology to Disease Management by J. Bosch,Andrew Burroughs,F. Lammert,D. Lebrec,Tilman Sauerbruch Pdf

The International Falk Symposium 162 in Dresden is a good example for the promises of history. Sixty years after the misery of the Second World War and the destruction of Dresden and 20 years after a long and threatening Cold War, scientists from more than 50 nations across the world met in a wonderfully reconstructed city to discuss a series of key lectures on the pathophysiology and clinical management of liver cirrhosis. Liver cirrhosis is a leading cause of morbidity and mortality worldwide. It is the fifth most common cause of death between the age of 25 and 45 years. To date, it is still not possible to inhibit or revert progression of cirrhosis in most patients. Accordingly, clinicians primarily deal with the various complications of cirrhosis, while liver transplantation is only available for selected patients. There has been tremendous progress in the understanding of liver fibrosis and cirrhosis since the last Falk Symposium devoted to this topic in 2000.

Author : Pere Ginès,Patrick S Kamath,Vicente Arroyo
Publisher : Springer Science & Business Media
Page : 583 pages
File Size : 49,5 Mb
Release : 2010-11-03
Category : Medical
ISBN : 9781607618669

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Chronic Liver Failure by Pere Ginès,Patrick S Kamath,Vicente Arroyo Pdf

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Author : Ned Wright
Publisher : Unknown
Page : 233 pages
File Size : 41,6 Mb
Release : 2020-09-15
Category : Medical
ISBN : 1632418754

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Hepatitis C: From Pathophysiology to Disease Management by Ned Wright Pdf

Hepatitis C is a liver disease that is caused by the hepatitis C virus. People infected by the virus do not exhibit symptoms initially but occasionally dark urine, yellow tinged skin, fever and abdominal pain may occur. The infection can potentially lead to liver disease and cirrhosis. The hepatitis C virus is spread due to the use of poorly sterilized medical equipment, transfusions, blood-to-blood contact and needlestick injuries. It may also spread when an infected mother gives birth to her baby. There is no vaccination against hepatitis C. However, hepatitis C can be prevented using a combination of harm reduction strategies, including treatment of substance abuse, provision of new syringes and needles, and screening of blood donors. Chronic infection with hepatitis C can be cured with antiviral medications such as simeprevir or sofosbuvir. This book covers in detail the clinical aspects of hepatitis C from pathophysiology to disease management. It unravels the recent studies in hepatitis C. A number of latest researches have been included to keep the readers up-to-date with the global concepts in this area of study.

Author : Pablo Muriel
Publisher : Academic Press
Page : 914 pages
File Size : 43,7 Mb
Release : 2017-03-02
Category : Medical
ISBN : 9780128043219

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Liver Pathophysiology by Pablo Muriel Pdf

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. Provides in vivo and in vitro models to study human liver pathology. Explains the beneficial effects of antioxidants on liver diseases. Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.

Author : Gary D. Hammer,Stephen J. McPhee
Publisher : McGraw Hill Professional
Page : 779 pages
File Size : 45,7 Mb
Release : 2014-03-22
Category : Medical
ISBN : 9780071806015

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Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E (ENHANCED EBOOK) by Gary D. Hammer,Stephen J. McPhee Pdf

A full-color, case-based review of the essentials of pathophysiology--covering all major organs and systems The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. Features 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed Checkpoint questions provide review and appear in every chapter Updates and revisions throughout this new edition reflect the latest research and developments Numerous tables and diagrams encapsulate important information Updated references for each chapter topic Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities.

Author : Samuel S. Lee,Richard Moreau
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 48,9 Mb
Release : 2015-01-22
Category : Medical
ISBN : 9781118412688

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Cirrhosis by Samuel S. Lee,Richard Moreau Pdf

Cirrhosis: a practical guide to management providesgastroenterologists and hepatologists with an up-to-date clinicalguide presenting the very best evidence-based practice in thediagnosis, treatment and management of liver cirrhosis and its manycomplications. Designed to offer practical guidance at alltimes, it provides doctors with an extremely useful tool in theclinical setting, with each chapter featuring diagnostic/managementalgorithms, key points and other pedagogic features. Divided into 2 parts, a diagnosis and pathophysiology section and amanagement of complications section, key topics include: - Diagnostic laboratory tests - Diagnostic imaging modalities - Acute-on chronic liver failure - Agents and drugs to avoid - End stage liver failure: liver transplant evaluation - Hepatocellular carcinoma Aimed at the specialist, as well as the practicing trainee at thetop-end of specialty training, the emphasis throughout is onproviding optimum clinical management guidance most relevant topracticing hepatologists and gastroenterologists, and is aninvaluable guide to this increasingly common condition.

Author : Vicente Arroyo,Pere Gin?s,Juan Rodés,Robert W. Schrier
Publisher : Wiley-Blackwell
Page : 568 pages
File Size : 41,6 Mb
Release : 1999-03-22
Category : Medical
ISBN : 0632043423

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Ascites and Renal Dysfunction in Liver Disease by Vicente Arroyo,Pere Gin?s,Juan Rodés,Robert W. Schrier Pdf

Ascites and Renal Dysfunction in Liver Disease is the only text of its kind to focus on the clinical management of ascites and related disorders in patients with chronic liver disease. Containing the contributions of some 55 renowned experts, this text provides an up-to-date, all-embracing examination of the physiologic and pathophysiologic relationships between liver disease and the kidney. Clear and comprehensive in nature, this major text includes an exhaustive description of all pathophysiologic mechanisms relevant to our understanding of renal dysfunction and ascites formation in cirrhosis. Current information regarding treatment and therapy for patients with cirrhosis and ascites is clearly and effectively presented. From pathogenesis to clinical management, and from theory to practice, this authoritative exploration of the subject is a unique and invaluable reference tool for the gastroenterologist, hepatologist, and nephrologist alike.

Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Publisher : Cambridge University Press
Page : 995 pages
File Size : 54,6 Mb
Release : 2007-05-07
Category : Medical
ISBN : 9781139464031

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Liver Disease in Children by Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Pdf

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 52,6 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Author : Regina Nelson
Publisher : Unknown
Page : 120 pages
File Size : 45,7 Mb
Release : 2016
Category : Medical
ISBN : 1634857194

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Liver Disease by Regina Nelson Pdf

This book discusses the diagnosis, treatment and management of liver disease. Chapter One reviews hepatic hydatidosis. Chapter Two explores the diagnosis, natural history, and management for patients with chronic hepatitis C (CHC). Chapter Three discusses scientific evidence that explains the relationship between metabolic syndrome, non- alcoholic fatty liver disease (NAFLD) and psoriasis and the treatment strategy for this co-morbid condition. Chapter Four examines the pathophysiology and treatment of liver cirrhosis. Chapter Five reviews surgical strategies to push up resection limits in liver disease and liver failure after surgery.

Author : Miranda L. Michelli
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 46,5 Mb
Release : 2011
Category : Liver
ISBN : 1612092489

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Liver Cirrhosis by Miranda L. Michelli Pdf

This book presents topical research in the study of liver cirrhosis, including etiologic types of end stage chronic liver disease; hepatocellular carcinoma screening in the cirrhotic patient; hepatic myofibroblasts and their role in liver fibrogenesis; the role of trace elements in the pathogenesis of liver cirrhosis and cell-based therapy for liver cirrhosis.

Author : Mark Feldman,Marvin H. Sleisenger,Bruce F. Scharschmidt
Publisher : Unknown
Page : 0 pages
File Size : 46,8 Mb
Release : 1998
Category : Gastrointestinal system
ISBN : 0721662919

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Gastrointestinal and Liver Disease by Mark Feldman,Marvin H. Sleisenger,Bruce F. Scharschmidt Pdf

Author : Jong Hoon Park,Curie Ahn
Publisher : Springer
Page : 126 pages
File Size : 45,9 Mb
Release : 2016-10-12
Category : Medical
ISBN : 9789811020414

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Cystogenesis by Jong Hoon Park,Curie Ahn Pdf

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.

Author : Roberto de Franchis,Alessandra Dell’Era
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 52,8 Mb
Release : 2014-01-25
Category : Medical
ISBN : 9781493900022

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Variceal Hemorrhage by Roberto de Franchis,Alessandra Dell’Era Pdf

Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.

Author : Pere Ginés,Vicente Arroyo,Juan Rodés,Robert W. Schrier
Publisher : John Wiley & Sons
Page : 464 pages
File Size : 52,8 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9781405143707

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Ascites and Renal Dysfunction in Liver Disease by Pere Ginés,Vicente Arroyo,Juan Rodés,Robert W. Schrier Pdf

There has been very little written on the interaction of the liverand kidney. This book addresses the increasing incidence andsignificance of diseases, such as ascites, renal dysfunction,cirrhosis and hypertension where both organs are involved. This textbook is essential, even for confirmed practitioners andcontains current information regarding treatment and therapy forpatients with cirrhosis and ascites, clearly and effectivelypresented by the top international experts within this field. The second edition is entirely revised and updated and placesgreater emphasis on therapy.