Lung Inflammation In Health And Disease

Author : Yong-Xiao Wang
Publisher : Unknown
Page : 384 pages
File Size : 55,8 Mb
Release : 2021
Category : Electronic books
ISBN : 303068749X

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Lung Inflammation in Health and Disease by Yong-Xiao Wang Pdf

Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

Author : Yong-Xiao Wang
Publisher : Unknown
Page : 412 pages
File Size : 45,8 Mb
Release : 2021
Category : Electronic books
ISBN : 3030630471

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Lung Inflammation in Health and Disease by Yong-Xiao Wang Pdf

Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung diseases are neither always effective, nor often condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases are not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung diseases, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, fellows, and students with new perspectives and concepts. The editor hopes this book will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

Author : Yong-Xiao Wang
Publisher : Springer Nature
Page : 412 pages
File Size : 55,7 Mb
Release : 2021-03-31
Category : Medical
ISBN : 9783030630461

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Lung Inflammation in Health and Disease, Volume I by Yong-Xiao Wang Pdf

Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung disease are neither effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

Author : Gage Phillips
Publisher : American Medical Publishers
Page : 0 pages
File Size : 54,6 Mb
Release : 2023-09-19
Category : Medical
ISBN : 9798887405766

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Lung Inflammation in Health and Disease by Gage Phillips Pdf

Inflammation refers to the process through which the immune system fights with injury, infection and other harmful substances. Lung inflammation can develop from toxin exposure, cystic fibrosis, chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), and asthma. Some common symptoms of lung inflammation are breathing problems, wheezing, chest pain or tightness, fatigue, lung pain, unintended weight loss and decreased appetite. Various types of diagnostic tests, including blood culture, pulse oximetry, lung biopsy, saliva test, sweat chloride test, and pulmonary function test can be used for the diagnosis of lung inflammation. Its treatment may involve oxygen therapy, physical therapy, surgery and medications like leukotriene modifiers, antifungals, biologic medications, antibiotics, corticosteroids, anti-inflammatories and bronchodilators. This book provides significant information on lung inflammation to help develop a good understanding of its effects in health and disease. A number of latest researches have been included to keep the readers up-to-date with the global concepts on this medical condition. Students, researchers, experts and all associated with the study of lung inflammation will benefit alike from this book.

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 50,5 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Mieczyslaw Pokorski
Publisher : Springer
Page : 100 pages
File Size : 51,6 Mb
Release : 2016-08-09
Category : Medical
ISBN : 9783319444857

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Pulmonary Infection and Inflammation by Mieczyslaw Pokorski Pdf

Pulmonary diseases are the major cause of human morbidity, taxing the health care system due to disease prevalence, chronicity, and social and fiscal costs. This book concentrates on the inflammatory and immunogenic settings of pulmonary disorders and related medical areas. Excessive inflammation causes lung injury and forms a conducive background for pathogenic infections, particularly in immuno-compromised hosts. Bacterial immuno-evasive strategies develop, leading to self-perpetuating pathologies. Inflammation also is an essential component of non-communicable lung diseases, including asthma and respiratory allergies, and smoking-related or granulomatous diseases. The chapters combine a strong grounding in basic science with extensive clinical knowledge and experience. Advances in diagnostics, as well as preventive and therapeutic aspects also are tackled. The book provides useful information to clinicians, researchers, health care and other medical professionals.

Author : Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams
Publisher : Academic Press
Page : 620 pages
File Size : 44,5 Mb
Release : 2020-08-04
Category : Technology & Engineering
ISBN : 9780128208885

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Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams Pdf

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases
Publisher : National Academies Press
Page : 200 pages
File Size : 49,7 Mb
Release : 2011-08-26
Category : Medical
ISBN : 9780309212199

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A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases by Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases Pdf

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data--including population surveys, cohort studies, disease registries, administrative health data, and vital statistics--contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Author : Thomas J. Rogers,Gerard J. Criner,William D. Cornwell
Publisher : Springer Science & Business Media
Page : 217 pages
File Size : 48,7 Mb
Release : 2013-10-12
Category : Medical
ISBN : 9781461473510

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Smoking and Lung Inflammation by Thomas J. Rogers,Gerard J. Criner,William D. Cornwell Pdf

Smoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases.

Author : Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove
Publisher : World Bank Publications
Page : 1449 pages
File Size : 51,8 Mb
Release : 2006-04-02
Category : Medical
ISBN : 9780821361801

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Disease Control Priorities in Developing Countries by Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove Pdf

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Author : Bernahrd Ryffel,Kian Fan Chung,Dieudonnée Togbe
Publisher : Frontiers Media SA
Page : 118 pages
File Size : 51,5 Mb
Release : 2021-09-08
Category : Medical
ISBN : 9782889712670

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Ozone as a Driver of Lung Inflammation and Innate Immunity, and as a Model for Lung Disease by Bernahrd Ryffel,Kian Fan Chung,Dieudonnée Togbe Pdf

Author : Yong-Xiao Wang
Publisher : Springer Nature
Page : 384 pages
File Size : 48,6 Mb
Release : 2021-05-21
Category : Medical
ISBN : 9783030687489

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Lung Inflammation in Health and Disease, Volume II by Yong-Xiao Wang Pdf

Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.

Author : Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent
Publisher : World Bank Publications
Page : 466 pages
File Size : 55,6 Mb
Release : 2017-11-17
Category : Medical
ISBN : 9781464805202

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Disease Control Priorities, Third Edition (Volume 5) by Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent Pdf

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Author : Thomas Martin
Publisher : CRC Press
Page : 624 pages
File Size : 43,9 Mb
Release : 2000-01-18
Category : Medical
ISBN : 082471931X

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Cytokines in Pulmonary Disease by Thomas Martin Pdf

Focusing on the role of the cytokine network in promoting immunity, this superb interdisciplinary collection intensively investigates the behavior of inflammatory mediators in the pathogenesis and resolution of pathogen-specific pulmonary infections-highlighting recent basic findings and discussing the latest results of clinical trials. Defines the vital role that cytokines play in host defense and the pathophysiology of infections associated with pulmonary disease, emphasizing the potential of immunomodulators and gene therapy in treatment. Cytokines in Pulmonary Disease provides state-of-the-art knowledge of the field of cytokines and pulmonary diseases in a single, authoritative source reviews the roles of cytokines in pathogen-specific infections, including tuberculosis, HIV-related infections, fungal pneumonias, cystic fibrosis, and other disorders assesses the rationale and efficacy of new approaches in both the prevention and treatment of pulmonary infectious disease examines the clinical applications and impact of cytokines in pulmonary disease and more. Written by leading international authorities in their respective fields, Cytokines in Pulmonary Disease will find a place on the bookshelves of specialists in pulmonary and critical care medicine, infectious diseases, surgery, immunology, microbiology, cell and molecular biology, and medical school and graduate students in these disciplines.

Author : Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess
Publisher : Springer
Page : 238 pages
File Size : 45,9 Mb
Release : 2019-02-19
Category : Medical
ISBN : 9783030111496

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Diseases of the Chest, Breast, Heart and Vessels 2019-2022 by Juerg Hodler,Rahel A. Kubik-Huch,Gustav K. von Schulthess Pdf

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.