Lymphocyte Immunization Therapy Lit In Reproductive Failures

Author : Mohan Raut,Mugdha Raut
Publisher : Springer Nature
Page : 150 pages
File Size : 41,8 Mb
Release : 2022-08-27
Category : Medical
ISBN : 9789811929601

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Lymphocyte Immunization Therapy (LIT) in Reproductive Failures by Mohan Raut,Mugdha Raut Pdf

Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis.This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective.The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained.The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy.The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers.The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.

Author : Irina Szmelskyj,Lianne Aquilina
Publisher : Elsevier Health Sciences
Page : 448 pages
File Size : 50,7 Mb
Release : 2014-10-08
Category : Medical
ISBN : 9780702050107

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Acupuncture for IVF and Assisted Reproduction by Irina Szmelskyj,Lianne Aquilina Pdf

The management of infertility using acupuncture is an expanding area of practice and one which is frequently rewarding for TCM acupuncture practitioners. Acupuncture for IVF and Assisted Reproduction has been specially prepared to meet the growing demand for information in this area and draws upon 20 years combined experience of the authors together with the latest evidence from both orthodox medicine and TCM. Richly illustrated and clearly written throughout, the book takes the reader through the anatomy and physiology of reproductive medicine (from both an orthodox and TCM perspective) and explains the underlying basis of orthodox medical fertility tests and investigations. The volume then explores the pathology and aetiology of TCM syndromes and shows how common fertility-related conditions, such as endometriosis and male factor infertility, affect Assisted Reproductive Technology (ART) success rates. It explains in great detail how to take a reproductive medical history and successfully diagnose TCM syndromes. Acupuncture for IVF and Assisted Reproduction also provides guidelines on how to regulate the menstrual cycle in preparation for IVF treatment and shows how lifestyle can affect fertility and ART success rates. Placing a strong emphasis on the practical aspects of patient care, Acupuncture for IVF and Assisted Reproduction contains an abundance of case history templates, algorithmic acupuncture treatment pathways and patient fact sheets and will be ideal for all acupuncture practitioners working in this field. "A must have for the bookshelf of any acupuncturist who is ever called upon to treat fertility issues - if you have room for one book this surely must be it." Reviewed by The Acupuncture Fertility Centre March 2015 "Practitioners of all levels of experience and TCM students should find it compelling reading and an invaluable companion to their learning." Reviewed by Stephen Clarke, Journal of the Australian Traditional Medicine Society May 2015 "This book is extremely well re-searched and referenced." Reviewed by Danny Maxwell on behalf of Journal of Chinese Medicine, February 2015 Simplifies complex information into easily accessible and understandable material Explains reproductive anatomy and physiology from the perspectives of both orthodox medicine and TCM Explains the underlying basis of orthodox medical fertility tests and investigations Explores the pathology and aetiology of TCM syndromes Provides detailed information on how to take a fertility medical history and how to diagnose TCM syndromes Presents the evidence for the influence of various lifestyle factors on fertility and ART success rates Provides guidelines on how to regulate the menstrual cycle in preparation for IVF treatment Explains how common fertility-related conditions such as endometriosis, Polycystic Ovary Syndrome, thyroid disease, and male factor infertility affect ART success rates Explains how to adapt acupuncture treatment to different ART protocols Provides case history templates, algorithmic acupuncture treatment pathways and patient fact sheets Explains how to manage patients with complex medical histories Looks at Repeated Implantation Failure, reproductive immunology dysfunction, and recurrent miscarriages Explains how to support patients if their IVF is unsuccessful and how to treat patients during early pregnancy Examines ethical considerations relevant to fertility acupuncture practice

Author : Gérard Chaouat,Olivier Sandra,Nathalie Lédée
Publisher : Bentham Science Publishers
Page : 982 pages
File Size : 43,8 Mb
Release : 2013-11-08
Category : Medical
ISBN : 9781608057337

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Immunology of Pregnancy 2013 by Gérard Chaouat,Olivier Sandra,Nathalie Lédée Pdf

Since a September, 1992, Nature article which read: “Can there be life without LIF?”, researchers now realize that the maternal immune system is both a foe (it can reject the conception) and a friend (immune cells and molecules are also necessary for successful pregnancy). Leukemia Inhibitory Factor (LIF) when absent, prevents embryo implantation in rodents. From fecundation to parturition, immunity acts as a Janus, required but potentially dangerous. However, the complexity and the diversity of immunity in pregnancy deters many from entering the field. This book will try to give a complete overview of immunity from gametes till parturition, in brief, but with complete chapters and subsections, each written by specialists in the field. The importance of the topic relies not only on “the riddle of the fetal allograft”, which is per se fascinating, but on its consequences, linked to the development of IVF and in general, Assisted Reproductive Technologies (ART) / Medicine. Since the discovery that there would not be (mammalian) life without LIF, it has become clear that Immune Molecules, and in general, transient post mating inflammatory reactions are required for successful implantation. Disruptions of this process can lead to implantation failure / sterility. In later stages of pregnancy immunological cells, mostly of the innate immune system, control formation of local spiral arteries. Finally, a state of tolerance establishes itself, whose “break’ leads to immune abortion and the vascular bed is further transformed and enlarged, till delivery, and here again “immunological cytokines” do play a major role and can eventually cause immune mediated abortion. Failure of, not just, the cytokine and cell recognition mediated dialogue, but also the pre and peri-implantation “preparation of the uterus”, as stated, leads to sterility, early pregnancy loss and recurrent abortions. There is also an increasingly stronger argument to implicate immunology in pre-eclampsia. Further still, immunology is also implicated in the control of local infection, mother to child transmission of pathogens (notably, but not limited to, HIV). Finally, pregnancy is the only known physiological phenomenon where the once named “suppressor T cells,” re-emerge as “regulatory T cells”, and play a cardinal role. This E-book provides a complete compendium of gynecological immunology, spanning from fecundation to delivery. Topics also include the role of various cell types (such as T regs ad NK cells) in implantation and uterine changes as well as the genetic regulation of immunological processes. As such it will be of interest not only to fundamental and reproductive immunologists, but more importantly, clinicians in obstetrics and gynecology.

Author : David K. James,Philip J. Steer,Carl P. Weiner,Bernard Gonik
Publisher : Elsevier Health Sciences
Page : 1798 pages
File Size : 53,8 Mb
Release : 2010-12-03
Category : Medical
ISBN : 9781455700004

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High Risk Pregnancy E-Book by David K. James,Philip J. Steer,Carl P. Weiner,Bernard Gonik Pdf

High Risk Pregnancy examines the full range of challenges in general obstetrics, medical complications of pregnancy, prenatal diagnosis, fetal disease, and management of labor and delivery. Drs. David James, Philip J. Steer, Carl P. Weiner, Bernard Gonik, Caroline Crowther, and Stephen Robson present an evidence-based approach to the available management options, equipping you with the most appropriate strategy for each patient. This comprehensive reference features the fully searchable text online at www.expertconsult.com, as well as more than 100 videos of imaging and monitoring. giving you easy access to the resources you need to manage high risk pregnancies. Prepare for clinical challenges and save time in addressing them thanks to expert advice on treatment options from international contributors. Find and apply the information you need quickly and easily through a consistent organization and at-a-glance summary boxes that discuss evidence-based management options. Access the fully searchable text online at www.expertconsult.com, along with links to Medline. View over 140 videos of detailed fetal imaging and monitoring that aid in diagnoses. Tap into recent developments in treatment and management in four new chapters—Global Maternal & Perinatal Health Issues; Recurrent Pregnancy Loss; Surveillance of the Fetus and its Indications; and Training for Obstetric Emergencies. Apply new evidence-based management options to treat genetic and constitutional factors leading to a high-risk pregnancy (such as diabetes, obesity, hypertension, and cardiac disease) through new and expanded coverage of these increasingly common presentations. Reference pregnancy-relevant laboratory values with an updated and comprehensive appendix on "Normal Values in Pregnancy." Effectively manage patients newly diagnosed with hematologic and immunologic malignancies, and explore the available drug options. Confirm your diagnoses with greater confidence thanks to full-color images throughout the text.

Author : Alan H. DeCherney
Publisher : Unknown
Page : 328 pages
File Size : 55,7 Mb
Release : 1986
Category : Health & Fitness
ISBN : UOM:39015010125261

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Reproductive Failure by Alan H. DeCherney Pdf

Author : Lei Huang,Andrew L. Mellor,Anatolij Horuzsko,Sha Wu
Publisher : Frontiers Media SA
Page : 388 pages
File Size : 45,6 Mb
Release : 2022-04-18
Category : Medical
ISBN : 9782889749454

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Immune Regulations in Reproductive Organs and Organ Transplant by Lei Huang,Andrew L. Mellor,Anatolij Horuzsko,Sha Wu Pdf

Author : Joanna Kwak-Kim
Publisher : Academic Press
Page : 457 pages
File Size : 49,7 Mb
Release : 2022-07-03
Category : Medical
ISBN : 9780323908061

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Immunology of Recurrent Pregnancy Loss and Implantation Failure by Joanna Kwak-Kim Pdf

Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease. Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information. In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches. Provides detailed immunological background for understanding the etiology and management of reproduction failure Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure Gives insights into various immunological and therapeutic approaches for reproduction failure

Author : Isabel Stabile,J. G. Grudzinskas,Tim Chard
Publisher : Springer Science & Business Media
Page : 239 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447119180

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Spontaneous Abortion by Isabel Stabile,J. G. Grudzinskas,Tim Chard Pdf

Sixteen British specialists pool their extensive knowledge of spontaneous abortion in one source. Their discussion is directly applicable to clinical situations and helps identify areas of debate and alternative methods.

Author : J. Bain,Wolf-Bernhard Schill,L. Schwarzstein
Publisher : Springer Science & Business Media
Page : 387 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642682230

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Treatment of Male Infertility by J. Bain,Wolf-Bernhard Schill,L. Schwarzstein Pdf

Our insight into the mechanisms of the physiology of reproduction has experienced a swift and constant development these last few years. The advent of more sophisticated diagnostic methods and their relatively easy clinical application allow for the incorporation of that knowledge into the evaluation of the infertile couple. These facts, together with an obvious change in social psychology, have facilitated the development of different specialities dealing with the problems of infertility. It is now possible in medical centers all around the world to undertake a better disposition of the infertile husband to look for advice, to be studied, and treated. Confronted with this situation we are still unable to offer specific therapy in most cases; however, empirically based therapy abounds. Advances in therapy have not kept pace with our increased physio logical knowledge and improved diagnostic techniques. Patho physiological mechanisms and etiological factors in male infertility are largely unknown. This has significantly hampered both clinical evaluation and advances in treatment allowing for frequent non scientific therapeutic incursions into the armamentarium of the an drologist. Several factors have given birth to therapeutic "fashions", which are bound to survive as long as this state of lack of knowledge con tinues. For example, we may ask whether the treatment of varicocele constitutes a fashion? Though we accept the treatment of varicocele as the best available treatment of male infertility, we do not know its mechanism of action and so we cannot predict a therapeutic result.

Author : Michelle Kenyon,Aleksandra Babic
Publisher : Springer
Page : 311 pages
File Size : 45,5 Mb
Release : 2018-03-14
Category : Medical
ISBN : 9783319500263

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The European Blood and Marrow Transplantation Textbook for Nurses by Michelle Kenyon,Aleksandra Babic Pdf

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Author : Elizabeth Katkin
Publisher : Simon & Schuster
Page : 320 pages
File Size : 46,8 Mb
Release : 2019-06-25
Category : Biography & Autobiography
ISBN : 9781501142376

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Conceivability by Elizabeth Katkin Pdf

The “Jason Bourne of fertility” (The New York Times Book Review) presents a personal and deeply informative account of one woman’s journey through the global fertility industry. On paper, conception may seem like a simple biological process, yet this is often hardly the case. While many would like to have children, the road toward conceiving and maintaining a pregnancy can be unexpectedly rocky and winding. Lawyer Elizabeth Katkin never imagined her quest for children would ultimately involve seven miscarriages, eight fresh IVF cycles, two frozen IVF attempts, five natural pregnancies, four IVF pregnancies, ten doctors, six countries, two potential surrogates, nine years, and roughly $200,000. Despite her three Ivy League degrees and wealth of resources, Katkin found she was woefully undereducated when it came to understanding and confronting her own difficulties having children. After being told by four doctors she should give up, but without an explanation as to what exactly was going wrong with her body, Katkin decided to look for answers herself. The global investigation that followed revealed that approaches to the fertility process taken in many foreign countries are vastly different than those in the US and UK. In Conceivability, Elizabeth Katkin, now a mother of two, exposes eye-opening information about the medical, financial, legal, scientific, emotional, and ethical issues at stake. “A well-researched, informative, and positive account of a very long journey to motherhood” (Kirkus Reviews), Conceivability sheds light on the often murky and baffling world of conception science. Her book is an invaluable and inspiring text that will be a boon to others navigating the deep and “choppy waters” of fertility treatment (Publishers Weekly), and her chronicle of one of the most difficult, painful, rewarding, and loving journeys a woman can take is as informative as it is poignant.

Author : Robert Kiltz,Maria Emmerich
Publisher : Unknown
Page : 128 pages
File Size : 44,8 Mb
Release : 2022
Category : Electronic
ISBN : 9798985220209

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Keto for Fertility Cookbook by Robert Kiltz,Maria Emmerich Pdf

Author : Keiji Kuroda,Jan J. Brosens,Siobhan Quenby,Satoru Takeda
Publisher : Springer
Page : 0 pages
File Size : 41,9 Mb
Release : 2019-02-11
Category : Medical
ISBN : 9811342156

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Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage by Keiji Kuroda,Jan J. Brosens,Siobhan Quenby,Satoru Takeda Pdf

This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.

Author : Karl H. Broer,Ismet Turanli
Publisher : Springer Science & Business Media
Page : 357 pages
File Size : 40,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642609619

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New Trends in Reproductive Medicine by Karl H. Broer,Ismet Turanli Pdf

In the last few years rapid advances have been made in reproductive medicine, making it necessary for those involved to regularly update their knowledge. The purpose of this book is to describe the state of the art in this field, making it possible for the reader to gain an orientation among all the diagnostic and therapeutic potentials of modern reproductive medicine in order to advise patients fully. Chapters from the fields of gynecology, and reproductive medicine in a specific sense provide knowledge about these subjects. Authors of international standing have contributed chapters on their specialties. These chapters together form a book describing the state of the art in the diagnosis and therapy of sterility in gynecology and andrology.

Author : Isabel Stabile,Tim Chard,Gedis Grudzinskas
Publisher : Springer Science & Business Media
Page : 210 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447133742

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Clinical Obstetrics and Gynaecology by Isabel Stabile,Tim Chard,Gedis Grudzinskas Pdf

The aim of this book is to provide a straightforward summary of the knowl edge required for examinations in specialist Obstetrics and Gynaecology. Part Two of the examination for Membership of the Royal College of Ob stetricians and Gynaecologists would be a good example. The volume is intended as a companion to the highly successful Basic Sciences for Ob stetrics and Gynaecology which covers the knowledge required for pre liminary examinations. Increasingly, examinations of all types are based on multiple choice ques tions (MCQ) or structured answer questions (SAQ). No apology is made for the fact that the present book addresses the sort of "fact" which lends itself to testing by this approach. Thus, there is little discussion of specula tive or contentious areas, no account of present or future research, and no references. Numerous excellent books are available which cover these top ics in a much fuller and more discursive manner, and the present volume does not seek to emulate them.