Macromolecular Crystallography

Macromolecular Crystallography Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Macromolecular Crystallography book. This book definitely worth reading, it is an incredibly well-written.

Introduction to Macromolecular Crystallography

Alexander McPherson
Introduction to Macromolecular Crystallography Book PDF

Author : Alexander McPherson
Publisher : John Wiley & Sons
Page : 284 pages
File Size : 52,5 Mb
Release : 2011-09-20
Category : Science
ISBN : 9781118210635

Get Book

Introduction to Macromolecular Crystallography by Alexander McPherson Pdf

A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.

Macromolecular Crystallography Protocols, Volume 1

Sylvie Doublie
Macromolecular Crystallography Protocols Volume 1 Book PDF

Author : Sylvie Doublie
Publisher : Springer Science & Business Media
Page : 283 pages
File Size : 55,8 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781597452090

Get Book

Macromolecular Crystallography Protocols, Volume 1 by Sylvie Doublie Pdf

Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization. The volume concludes with a survey of available crystallographic software.

Macromolecular Crystallography Protocols, Volume 2

Sylvie Doublie
Macromolecular Crystallography Protocols Volume 2 Book PDF

Author : Sylvie Doublie
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 50,6 Mb
Release : 2008-02-05
Category : Science
ISBN : 9781597452663

Get Book

Macromolecular Crystallography Protocols, Volume 2 by Sylvie Doublie Pdf

In the decade since publication of the first edition this book, the field has seen several major developments. These developments have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I is dedicated to crystallization and ways to increase the odds of obtaining crystals in macromolecules. Volume 2 covers both computational methods for characterizing crystals and solving structures.

Macromolecular Crystallography

Maria Armenia Carrondo,Paola Spadon
Macromolecular Crystallography Book PDF

Author : Maria Armenia Carrondo,Paola Spadon
Publisher : Springer
Page : 208 pages
File Size : 47,6 Mb
Release : 2011-12-01
Category : Science
ISBN : 9789400725300

Get Book

Macromolecular Crystallography by Maria Armenia Carrondo,Paola Spadon Pdf

This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.

Macromolecular Crystallography

Charles W. Carter,Robert M. Sweet
Macromolecular Crystallography Book PDF

Author : Charles W. Carter,Robert M. Sweet
Publisher : Gulf Professional Publishing
Page : 752 pages
File Size : 43,8 Mb
Release : 1997
Category : Computer simulation
ISBN : 0121827771

Get Book

Macromolecular Crystallography by Charles W. Carter,Robert M. Sweet Pdf

Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Phases * Map interpretation and refinement * Analysis and software.

Macromolecular Crystallography

Mark R. Sanderson,Jane V. Skelly
Macromolecular Crystallography Book PDF

Author : Mark R. Sanderson,Jane V. Skelly
Publisher : OUP Oxford
Page : 304 pages
File Size : 44,9 Mb
Release : 2007-08-23
Category : Science
ISBN : 9780191523427

Get Book

Macromolecular Crystallography by Mark R. Sanderson,Jane V. Skelly Pdf

Macromolecular Crystallography is the study of macromolecules (proteins and nucleic acids) using X-ray crystallographic techniques in order to determine their molecular structure. The knowledge of accurate molecular structures is a pre-requisite for rational drug design, and for structure-based function studies to aid the development of effective therapeutic agents and drugs. The successful determination of the complete genome (genetic sequence) of several species (including humans) has recently directed scientific attention towards identifying the structure and function of the complete complement of proteins that make up that species; a new and rapidly growing field of study called 'structural genomics'. There are now several important and well-funded global initiatives in operation to identify all of the proteins of key model species. One of the main requirements for these initiatives is a high-throughput crystallization facility to speed-up the protein identification process. The extent to which these technologies have advanced, calls for an updated review of current crystallographic theory and practice. This practical reference book features the latest conventional and high-throughput methods, and includes contributions from a team of internationally recognized leaders and experts. It will be of relevance and use to graduate students, research scientists and professionals currently working in the field of conventional and high-throughput macromolecular crystallography.

Protein Crystallography

Alexander Wlodawer,Zbigniew Dauter,Mariusz Jaskolski
Protein Crystallography Book PDF

Author : Alexander Wlodawer,Zbigniew Dauter,Mariusz Jaskolski
Publisher : Humana Press
Page : 672 pages
File Size : 46,9 Mb
Release : 2017-06-02
Category : Science
ISBN : 1493969986

Get Book

Protein Crystallography by Alexander Wlodawer,Zbigniew Dauter,Mariusz Jaskolski Pdf

This volume provides methods for modern macromolecular crystallography, including all steps leading to crystal structure determination and analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein Crystallography aims to ensure successful results in the further study of this vital field.

Methods in Macromolecular Crystallography

North Atlantic Treaty Organization. Scientific Affairs Division
Methods in Macromolecular Crystallography Book PDF

Author : North Atlantic Treaty Organization. Scientific Affairs Division
Publisher : IOS Press
Page : 220 pages
File Size : 55,5 Mb
Release : 2001
Category : Science
ISBN : 1586030809

Get Book

Methods in Macromolecular Crystallography by North Atlantic Treaty Organization. Scientific Affairs Division Pdf

This volume contains 20 papers from two courses ("Methods for Macromolecular Crystallography" and "Chemical Prospective in Crystallography of Molecular Biology") held during the late spring of 2000 in Reice, Italy. The papers discuss crystals, synchrotrons, detector development, data processing, ab initio phasing and high and low resolution, molecular placement, experimental phase measurement, density modification methods, map improvements, interpretation of electron density maps, automatic structure determination, and the dissection of ultra-high resolution structures. c. Book News Inc.

Time-resolved Macromolecular Crystallography

Royal Society (Great Britain)
Time resolved Macromolecular Crystallography Book PDF

Author : Royal Society (Great Britain)
Publisher : Oxford [England] ; New York : Oxford University Press
Page : 194 pages
File Size : 51,9 Mb
Release : 1992
Category : Language Arts & Disciplines
ISBN : 0198557817

Get Book

Time-resolved Macromolecular Crystallography by Royal Society (Great Britain) Pdf

The papers presented in this volume report the striking progress X-ray diffraction has facilitated in the study of structural molecular biology. Coupled with the revival of the Laue method, the advent of high-intensity synchrotron radiation sources has made possible the rapid collection of X-ray crystallography data, thereby allowing protein and virus crystallography to progress from studies of equilibrium structures to time-resolved studies of structures at reaction stages. The book also details the many recent technological developments in physics, chemistry and biochemistry that have been critical for the full exploitation of the synchrotron Laue method in the study of dynamic events in crystals. Necessary future developments are discussed.

Macromolecular Crystallography, Part C

Charles W. Carter Jr.
Macromolecular Crystallography Part C Book PDF

Author : Charles W. Carter Jr.
Publisher : Elsevier
Page : 405 pages
File Size : 54,7 Mb
Release : 2003-12-15
Category : Science
ISBN : 9780080497099

Get Book

Macromolecular Crystallography, Part C by Charles W. Carter Jr. Pdf

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals* Methodological methods data analysis

Macromolecular Crystallography with Synchrotron Radiation

John R. Helliwell
Macromolecular Crystallography with Synchrotron Radiation Book PDF

Author : John R. Helliwell
Publisher : Cambridge University Press
Page : 620 pages
File Size : 40,9 Mb
Release : 1992
Category : Science
ISBN : 9780521544047

Get Book

Macromolecular Crystallography with Synchrotron Radiation by John R. Helliwell Pdf

This highly illustrated monograph provides a comprehensive treatment of the study of the structure and function of the molecules of life--proteins, nucleic acids, and viruses--using synchrotron radiation and crystallography. Beginning with chapters on the fundamentals of macromolecular crystallography and macromolecular structure, the book goes on to review the sources and properties of synchrotron radiation, instrumentation, and monochromatic data collection. There are also chapters on the Laue method, on diffuse X-ray scattering, and on variable wavelength anomalous dispersion methods. The book concludes with a description and survey of applications including studies at high resolution, the use of small crystals, the study of large unit cells, and time-resolved crystallography (particularly of enzymes). Appendices are provided that present essential information for the synchrotron user as well as information about synchrotron facilities currently available.

Evolving Methods for Macromolecular Crystallography

Randy J. Read,Joel L. Sussman
Evolving Methods for Macromolecular Crystallography Book PDF

Author : Randy J. Read,Joel L. Sussman
Publisher : Springer Science & Business Media
Page : 193 pages
File Size : 42,6 Mb
Release : 2007-07-20
Category : Science
ISBN : 9781402063169

Get Book

Evolving Methods for Macromolecular Crystallography by Randy J. Read,Joel L. Sussman Pdf

This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.

Direct Methods, Macromolecular Crystallography And Crystallographic Statistics - Proceedings Of Winter School

H Schenk,A J C Wilson,S Parthasarathy
Direct Methods Macromolecular Crystallography And Crystallographic Statistics Proceedings Of Winter School Book PDF

Author : H Schenk,A J C Wilson,S Parthasarathy
Publisher : World Scientific
Page : 441 pages
File Size : 48,5 Mb
Release : 1987-02-01
Category : Electronic
ISBN : 9789813201774

Get Book

Direct Methods, Macromolecular Crystallography And Crystallographic Statistics - Proceedings Of Winter School by H Schenk,A J C Wilson,S Parthasarathy Pdf

Vasopressin is a hormone which has an increasingly important profile. Not only does it play a physiologically significant role in renal water regulation but it also has other renal actions and plays a role in overall cardiovascular control. Even more interesting is the recent growing interest in its potential effects on the brain, notably its influence on specific behaviours.This monograph about the polypeptide vasopressin covers all aspects relating to the production, control of release, and actions of this molecule within the body, including its roles as a hormone and as a central neurotransmitter. A consideration of the evolution of the molecule across the species and a brief historical perspective are also included. Clinical conditions associated with hypo- and hyper-production states are considered together with aspects of treatment, in addition to other clinical correlates./a

Protein Crystallography

Eaton E. Lattman,Patrick J. Loll
Protein Crystallography Book PDF

Author : Eaton E. Lattman,Patrick J. Loll
Publisher : JHU Press
Page : 149 pages
File Size : 44,9 Mb
Release : 2008-04-28
Category : Science
ISBN : 9780801896842

Get Book

Protein Crystallography by Eaton E. Lattman,Patrick J. Loll Pdf

The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of X-rays to determine a protein’s three-dimensional molecular structure. Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use clear examples and abundant illustrations to provide a concise and accessible primer on protein crystallography. Discussing the basics of diffraction, the behavior of two- and three-dimensional crystals, phase determination (including MIR and MAD phasing and molecular replacement), the Patterson function, and refinement, Lattman and Loll provide a complete overview of this important technique, illuminated by physical insights. The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

Macromolecular Crystallography Protocols, Volume 1

Sylvie Doublie
Macromolecular Crystallography Protocols Volume 1 Book PDF

Author : Sylvie Doublie
Publisher : Humana Press
Page : 0 pages
File Size : 45,8 Mb
Release : 2010-11-10
Category : Science
ISBN : 161737475X

Get Book

Macromolecular Crystallography Protocols, Volume 1 by Sylvie Doublie Pdf

Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization. The volume concludes with a survey of available crystallographic software.