Management Of Infections In The Immunocompromised Host

Author : Brahm H. Segal
Publisher : Springer
Page : 445 pages
File Size : 52,7 Mb
Release : 2018-06-18
Category : Medical
ISBN : 9783319776743

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Management of Infections in the Immunocompromised Host by Brahm H. Segal Pdf

This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies, adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.Management of Infections in the Immunocompromised Host is a valuable resource for infectious diseases specialists, immunologists, oncologists, hematologists, general physicians, students, researchers, and all other working with immunocompromised patients.

Author : Simon Fox,Brian Angus,Thomas Rawlinson,Angela Minassian
Publisher : Oxford University Press, USA
Page : 385 pages
File Size : 44,5 Mb
Release : 2019-02-06
Category : Medical
ISBN : 9780198789987

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Osh Infection in the Immunocompromised Host by Simon Fox,Brian Angus,Thomas Rawlinson,Angela Minassian Pdf

There is an increasing number of immunocompromised patients across a widening range of specialities in medicine. Patients with underlying malignancy, as well as transplant patients, are now living longer in a vulnerable immune state. Previously, patients were only seen by small specialist transplant, haematology, or oncology teams. Modern techniques mean that patients undergoing care in many specialities such as dermatology, rheumatology, gastroenterology, and acute general medicine, are being immunosuppressed to modify their underlying disease, and treated directly by their own specialists. The most pressing problems that these patients suffer from are usually related to fever and infection. The Oxford Specialist Handbook of Infection in the Immunocompromised Host is a comprehensive guide for medical staff caring for immunocompromised patients in a hospital setting. Divided into three sections, it is the ideal source for clear, up-to-date information needed on the ward. The book starts with a background of the field, followed by a section that provides a 'host', or patient-centred, approach to presentations in different immunocompromised states. It discusses the assessment, investigation, and management of clinical syndromes in patients with primary immunodeficiency, HIV infection, immunodeficiency as a result of therapeutic immunosuppression, haematological and solid organ malignancy, and immunodeficiency related to organ transplant. In addition, it covers medical conditions resulting in defective immunity, such as diabetes, mellitus, and chronic renal failure, and provides information on travel in the immunocompromised host. The third section provides a pathogen-centred approach to the investigation and management of viral, bacterial, parasitic, and fungal infections of particular relevance to the immunocompromised host. Combining hospital and laboratory guidelines with recent research, the Oxford Specialist Handbook of Infection in the Immunocompromised Host highlights the importance of diagnoses and empirical treatments. Ideal for medical staff working in infectious diseases, ITU, haematology and oncology, transplants, HIV/GUM, rheumatology, and general medicine, it also considers the diagnostic dilemmas encountered in a clinical setting. This handbook is also a valuable resource for when preparing for the UK SCE examinations in these topics, and the MRCP.

Author : Paul Actor,Alan Evangelista,James Poupard,Eileen Hinks
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468412598

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Infections in the Immunocompromised Host by Paul Actor,Alan Evangelista,James Poupard,Eileen Hinks Pdf

The subject matter of this volume, the basis for which was a conference held in Philadelphia which focused on the subject of infections, including their diagnosis and treatment, in immunocompromised individuals. The material is of particular importance today when placed against the background of the rapid spread of acquired immunodeficiency syndrome (AIDS). The first section dealt with the general subject of the immunocompromised host. Here, reviewed in detail, were the epidemiological and clinical aspects of opportunistic infections in patients with defective immune responses. It is widely acknowledged that infections are a major complication of the neoplastic process. Cancer-bearing patients are more prone to certain kinds of infectious and cancer chemotherapy almost always increases susceptibility to such infections. Depending upon the basic disease process of the cancer, a specific array of infectious diseases can be predicted. Patients altered in thymus-derived lymphocyte populations or mononuclear phagocyte capabilities resulting in defects in cell mediated immunity or delayed hypersensitivity become highly susceptible to certain groups of organisms, whereas, profoundly neutropenic patients usually become infected with different organisms. The types of infections noted are relatively predictable for the type of immune defect, with some variations according to epidemiological factors. Major advances have been made in the early diagnosis and treatment of infectious complications with increasingly effective antimicrobial agents and increasing knowledge of their use. The application of so-called preventive procedures has had limited value to date, including immunotherapy, which appears to hold much promise.

Author : M. Schrappe,H. Seifert
Publisher : Wiley-Blackwell
Page : 158 pages
File Size : 55,9 Mb
Release : 1995-03-09
Category : Science
ISBN : 3894122005

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Infection Control in the Immunocompromised Host by M. Schrappe,H. Seifert Pdf

Infection control is one of the major challenges of medicine in the future. The management of infectious diseases adds a substantial burden to the overall health care cost worldwide. Therefore, the prevention of infection is important, especially in view of the increasing number of patients with impaired host defenses due to serious underlying diseases like cancer and HIV infection, who are prone to a multitude of opportunistic infections. In developing countries, even more people are at risk of infectious diseases, and resoures are limited. This book covers important aspects of infection control in patients with hematologic disorders, with HIV infection and in patients in developing countries.

Author : Pranatharthi H. Chandrasekar
Publisher : Oxford University Press
Page : 425 pages
File Size : 50,6 Mb
Release : 2016
Category : Medical
ISBN : 9780199938568

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Infections in the Immunosuppressed Patient by Pranatharthi H. Chandrasekar Pdf

Infections in the Immunosuppressed Patient offers an illustrated, case-based matrix for treatment of infections across all types of immunosuppressed patients. As the challenges of managing these infections continues to evolve, this collection offers lucid, authoritative guidance to diagnosing and treating these infections effectively. Comprising 81 cases from leading experts across specialties, this collection offers a guide to both common and uncommon presentations of infections in: · Cancer patients · Solid-organ transplant recipients · Stem-cell recipients · Patients on immunosuppressive drugs · Patients with other immunosuppressive conditions Supplemented with rich color illustrations and insights from more than 100 experts, Infections in the Immunosuppressed Patient is the new benchmark reference work for treatment of these difficult cases.

Author : R. Rubin
Publisher : Springer Science & Business Media
Page : 703 pages
File Size : 45,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461566458

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Clinical Approach to Infection in the Compromised Host by R. Rubin Pdf

"Infection in the Compromised Host" has become a classic chapter in textbooks devoted to infectious diseases and internal medicine. The numbers of compromised hosts are increasing in the era of modem medicine because of our expanded capabilities to deal with difficult diseases, especially neoplasms. As a consequence, microbiologic complications related to the intensive care administered to these patients are increasing as well. Under these circum stances, not only does the underlying illness create conditions favorable for the development of unusual infections, but often the therapy contributes to the acquisition of potential pathogens that turn into agents responsible for severe and frequently fatal disease. Granulocytopenia and immunosuppression have been the two key fac tors in predisposing patients with cancer and other serious diseases to severe bacterial infections. Colonization by hospital-acquired pathogens and breaks in the anatomic barriers-as a result of disease or medical intervention-have contributed to the high incidence of infectious diseases in these patients. Although there is some overlap between the types of infection in granulocytopenic and immunosuppressed hosts, each ofthese clinical entities has distinctive features thatjustify considering them separately, reserving the term immunocompromised hosts only when refer ring to patients who are predisposed to opportunistic infections. For about two decades, infections in granulocytopenic patients have attracted the atten tion of clinicians because they represent a model for the study of antimicrobial drugs in hosts deprived of an essential element of defense against bacterial infection, that is, an adequate number of normally functioning granulocytes.

Author : Carlos Agusti,Antoni Torres
Publisher : John Wiley & Sons
Page : 456 pages
File Size : 47,7 Mb
Release : 2009-07-08
Category : Medical
ISBN : 0470714182

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Pulmonary Infection in the Immunocompromised Patient by Carlos Agusti,Antoni Torres Pdf

The immuno-compromised patient is more susceptible to a broader range of infections than others, and infections of the respiratory tract are among the first and most common to be encountered. In this book the authors review current options for management for a group of patients that present unique challenges to the clinician, and for whom the choices of effective therapy are often limited. Most up to date book available dedicated specifically to this topic Major management issue in respiratory medicine for critical care, transplant and cancer patients Reviews important new advances in therapeutics, including drug resistance

Author : Roger Finch,Peter Davey,Mark H. Wilcox,William Irving
Publisher : OUP Oxford
Page : 409 pages
File Size : 55,9 Mb
Release : 2012-01-05
Category : Medical
ISBN : 9780191628658

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Antimicrobial Chemotherapy by Roger Finch,Peter Davey,Mark H. Wilcox,William Irving Pdf

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Author : M. Glauser,Philip A. Pizzo
Publisher : Saunders Limited.
Page : 504 pages
File Size : 49,8 Mb
Release : 2000
Category : Medical
ISBN : UOM:39015049677324

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Management of Infections in Immunocompromised Patients by M. Glauser,Philip A. Pizzo Pdf

The book provides a practical, clinically useful guide for any physician involved in the care of immunocompromised patients, written by world class specialists. The text is presented clearly and consistently with design features to increase accessibility of information. The thinking and questioning patterns of physicianswho refer to a specialist for help are closely followed and all the commonly asked questions are answered. Concise, practical and clinically relevant Provides Clinicians of all disciplines with access to specialist advice Covers the most commonly asked questions about treatment of the immunocompromised patient

Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
Page : 672 pages
File Size : 54,6 Mb
Release : 2017-04-17
Category : Medical
ISBN : 9780190628635

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CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Pdf

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Author : John R Wingard,Elias Anaissie
Publisher : CRC Press
Page : 704 pages
File Size : 46,9 Mb
Release : 2019-08-30
Category : Electronic
ISBN : 0367392364

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Fungal Infections in the Immunocompromised Patient by John R Wingard,Elias Anaissie Pdf

Unlike any other source on the subject, this reference provides an up-to-date account of fungal syndromes in immunocompromised patients and provides expert descriptions of their clinical manifestations and settings in which they cause illness-covering the pros and cons of current and emerging diagnostic measures, techniques to incorporate new diagnostic tools and treatments into established clinical practices, and the most recent therapeutic strategies in patient care.

Author : Werner Hacke,D.F. Hanley,A.H. Ropper,K.M. Einhäupl,T.P. Bleck,M.N. Diringer
Publisher : Springer Science & Business Media
Page : 1052 pages
File Size : 50,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642876028

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Neurocritical Care by Werner Hacke,D.F. Hanley,A.H. Ropper,K.M. Einhäupl,T.P. Bleck,M.N. Diringer Pdf

A Quick Reference Text! Easy to read and practical in design, Neurocritical Care is the book specialists will turn to for quick reference. It concentrates on management problems, from diagnostic procedures to therapeutic strategies. Exact descriptions are given for treatment procedures, and it is easy to find the appropriate treatment for a given patient. International Expertise! More than 100 authors from North America have contributed to the book. The different strategies used on either side of the Atlantic have been described, the sections on neuroimaging have been reviewed by a neuroradiologist. Comprehensive in Scope! Both frequent and rare neurological diseases that may require critical care treatment and subjects of more general interest such as monitoring strategies, ethical problems, brain death and neurological disorders in internal medicine have been covered. Pathophysiology is also discussed, insomuch as it is important for understanding the treatment strategies.

Author : Jan Verhoef,Phillip K. Peterson,Paul G. Quie
Publisher : Elsevier-North-Holland Biomedical Press
Page : 332 pages
File Size : 40,9 Mb
Release : 1980
Category : Medical
ISBN : WISC:89004968327

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Infections in the Immunocompromised Host by Jan Verhoef,Phillip K. Peterson,Paul G. Quie Pdf

Author : Randall T. Hayden,Karen C. Carroll,Yi-Wei Tang,Donna M. Wolk
Publisher : John Wiley & Sons
Page : 794 pages
File Size : 54,5 Mb
Release : 2020-07-16
Category : Medical
ISBN : 9781555819040

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Diagnostic Microbiology of the Immunocompromised Host by Randall T. Hayden,Karen C. Carroll,Yi-Wei Tang,Donna M. Wolk Pdf

Strategies for providing optimal care to this high-risk patient group The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care. This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang and Donna Wolk, assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology) future diagnostic technologies and their potential impact on the field Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host.

Author : Zelalem Temesgen,Larry M. Baddour,Stacey Rizza
Publisher : Elsevier Health Sciences
Page : 307 pages
File Size : 51,5 Mb
Release : 2020-12-15
Category : Medical
ISBN : 9780323695794

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A Rational Approach to Clinical Infectious Diseases by Zelalem Temesgen,Larry M. Baddour,Stacey Rizza Pdf

Written specifically for non-infectious disease specialists in both inpatient and outpatient settings, A Rational Approach to Clinical Infectious Diseases provides concise, practical guidance that mimics the decision-making process and reasoning employed by an ID physician. Using clear, understandable language, Dr. Zelalem Temesgen and his esteemed colleagues at the Mayo Clinic present the art and the context of infectious diseases together with the science, helping non-specialists apply a rational approach to the diagnosis and treatment of infectious conditions. Clearly explains the rationale of opting for one particular treatment or length of course over another in order to arrange appropriate management and follow-up. Provides focused ID decision support to questions such as: What diagnostic test should I order? What is the correct antibiotic for this patient/geographical region? Are IV or oral antibiotics most appropriate? How long should the antibiotic course be and when should it be de-escalated? What special considerations should be taken in immunocompromised patients? How often should complex infections be followed up? Uses a succinct, easy-to-read writing style, following a consistent format: Important characteristics/epidemiology; Clinical related data; Rash characteristics; Ancillary diagnostic studies; Treatment; and Other. Provides visual and quick-reference support with dozens of figures and tables throughout the text. Contains invaluable guidance to help non-specialists provide the best care for patients, stem antibiotic misuse and resistance, avoid adverse drug events, and avoid unnecessary costs.