Mass Action In The Nervous System

Author : Bozzano G Luisa
Publisher : Elsevier
Page : 510 pages
File Size : 46,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323140201

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Mass Action in the Nervous System by Bozzano G Luisa Pdf

Mass Action in the Nervous System: Examination of the Neurophysiological Basis of Adaptive Behavior through the EEG focuses on the neural mechanisms and the behavioral significance of the electroencephalogram, with emphasis on observations made on the mammalian olfactory system. Organized into seven chapters, this book begins with a brief nonmathematical review of the concept of the neuron and the interrelations among neurons that lead to the formation of interactive masses. Some chapters follow on the linear properties of neurons and their parts; the ionic hypothesis; the nonlinear input-output relations of neurons in masses expressed in terms of amplitude-dependent coefficients in linear differential equations; and the relations between the states of activity of neurons. Subsequent chapters describe the properties resulting from feedback within neural masses; the effects of the nonlinearities in the input-output relations of neurons on the behavior of masses; and some inferences concerning the mechanisms of neural signal processing at the level of neural masses. The book is a model for an advanced text in neurophysiology, and some understanding is assumed of the elements of the fields of linear analysis, probability, statistics, theory of potential, neuroanatomy, electrophysiology, neuropharmacology, and experimental psychology.

Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Page : 195 pages
File Size : 45,8 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309045292

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Discovering the Brain by National Academy of Sciences,Institute of Medicine,Sandra Ackerman Pdf

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publisher : National Academies Press
Page : 610 pages
File Size : 47,9 Mb
Release : 2000-11-13
Category : Social Science
ISBN : 9780309069885

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From Neurons to Neighborhoods by National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Pdf

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Author : Yan M. Yufik,Biswa Sengupta,Karl Friston
Publisher : Frontiers Media SA
Page : 137 pages
File Size : 53,8 Mb
Release : 2017-11-30
Category : Electronic book
ISBN : 9782889453405

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Self-Organization in the Nervous System by Yan M. Yufik,Biswa Sengupta,Karl Friston Pdf

This special issue reviews state-of-the-art approaches to the biophysical roots of cognition. These approaches appeal to the notion that cognitive capacities serve to optimize responses to changing external conditions. Crucially, this optimisation rests on the ability to predict changes in the environment, thus allowing organisms to respond pre-emptively to changes before their onset. The biophysical mechanisms that underwrite these cognitive capacities remain largely unknown; although a number of hypotheses has been advanced in systems neuroscience, biophysics and other disciplines. These hypotheses converge on the intersection of thermodynamic and information-theoretic formulations of self-organization in the brain. The latter perspective emerged when Shannon’s theory of message transmission in communication systems was used to characterise message passing between neurons. In its subsequent incarnations, the information theory approach has been integrated into computational neuroscience and the Bayesian brain framework. The thermodynamic formulation rests on a view of the brain as an aggregation of stochastic microprocessors (neurons), with subsequent appeal to the constructs of statistical mechanics and thermodynamics. In particular, the use of ensemble dynamics to elucidate the relationship between micro-scale parameters and those of the macro-scale aggregation (the brain). In general, the thermodynamic approach treats the brain as a dissipative system and seeks to represent the development and functioning of cognitive mechanisms as collective capacities that emerge in the course of self-organization. Its explicanda include energy efficiency; enabling progressively more complex cognitive operations such as long-term prediction and anticipatory planning. A cardinal example of the Bayesian brain approach is the free energy principle that explains self-organizing dynamics in the brain in terms of its predictive capabilities – and selective sampling of sensory inputs that optimise variational free energy as a proxy for Bayesian model evidence. An example of thermodynamically grounded proposals, in this issue, associates self-organization with phase transitions in neuronal state-spaces; resulting in the formation of bounded neuronal assemblies (neuronal packets). This special issue seeks a discourse between thermodynamic and informational formulations of the self-organising and self-evidencing brain. For example, could minimization of thermodynamic free energy during the formation of neuronal packets underlie minimization of variational free energy?

Author : Thomas R. Knösche,Jens Haueisen
Publisher : Springer Nature
Page : 429 pages
File Size : 50,6 Mb
Release : 2022-10-01
Category : Medical
ISBN : 9783030749187

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EEG/MEG Source Reconstruction by Thomas R. Knösche,Jens Haueisen Pdf

This textbook provides a comprehensive and didactic introduction from the basics to the current state of the art in the field of EEG/MEG source reconstruction. Reconstructing the generators or sources of electroencephalographic and magnetoencephalographic (EEG/MEG) signals is an important problem in basic neuroscience as well as clinical research and practice. Over the past few decades, an entire theory, together with a whole collection of algorithms and techniques, has developed. In this textbook, the authors provide a unified perspective on a broad range of EEG/MEG source reconstruction methods, with particular emphasis on their respective assumptions about sources, data, head tissues, and sensor properties. An introductory chapter highlights the concept of brain imaging and the particular importance of the neuroelectromagnetic inverse problem. This is followed by an in-depth discussion of neural information processing and brain signal generation and an introduction to the practice of data acquisition. Next, the relevant mathematical models for the sources of EEG and MEG are discussed in detail, followed by the neuroelectromagnetic forward problem, that is, the prediction of EEG or MEG signals from those source models, using biophysical descriptions of the head tissues and the sensors. The main part of this textbook is dedicated to the source reconstruction methods. The authors present a theoretical framework of the neuroelectromagnetic inverse problem, centered on Bayes’ theorem, which then serves as the basis for a detailed description of a large variety of techniques, including dipole fit methods, distributed source reconstruction, spatial filters, and dynamic source reconstruction methods. The final two chapters address the important topic of assessment, including verification and validation of source reconstruction methods, and their actual application to real-world scientific and clinical questions. This book is intended as basic reading for anybody who is engaged with EEG/MEG source reconstruction, be it as a method developer or as a user, including advanced undergraduate students, PhD students, and postdocs in neuroscience, biomedical engineering, and related fields.

Author : Gianfranco Minati,Mario Abram,Eliano Pessa
Publisher : World Scientific
Page : 725 pages
File Size : 42,8 Mb
Release : 2012
Category : Computers
ISBN : 9789814383325

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Methods, Models, Simulations and Approaches Towards a General Theory of Change - Proceedings of the Fifth National Conference on Systems Science by Gianfranco Minati,Mario Abram,Eliano Pessa Pdf

The book contains the Proceedings of the 2010 Conference of the Italian Systems Society. Papers deal with the interdisciplinary study of processes of changing related to a wide variety of specific disciplinary aspects. Classical attempts to deal with them, based on generalising approaches used to study the movement of bodies and environmental influence, have included ineffective reductionistic simplifications. Indeed changing also relates, for instance, to processes of acquisition and varying properties such as for software; growing and aging biological systems; learning/cognitive systems; and socio-economic systems growing and developing through innovations. Some approaches to modelling such processes are based on considering changes in structure, e.g., phase-transitions. Other approaches are based on considering (1) periodic changes in structure as for processes of self-organisation; (2) non-periodic but coherent changes in structure, as for processes of emergence; (3) the quantum level of description. Papers in the book study the problem considering its transdisciplinary nature, i.e., systemic properties studied per se and not within specific disciplinary contexts. The aim of these studies is to outline a transdisciplinary theory of change in systemic properties. Such a theory should have simultaneous, corresponding and eventually hierarchical disciplinary aspects as expected for a general theory of emergence. Within this transdisciplinary context, specific disciplinary research activities and results are assumed to be mutually represented as within a philosophical and conceptual framework based on the theoretical centrality of the observer and conceptual non-separability of context and observer, related to logically open systems and Quantum Entanglement. Contributions deal with such issues in interdisciplinary ways considering theoretical aspects and applications from Physics, Cognitive Science, Biology, Artificial Intelligence, Economics, Architecture, Philosophy, Music and Social Systems.

Author : Stephen G. Waxman
Publisher : MIT Press
Page : 546 pages
File Size : 44,7 Mb
Release : 2003-01-24
Category : Medical
ISBN : 026273155X

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Form and Function in the Brain and Spinal Cord by Stephen G. Waxman Pdf

This book reflects Stephen Waxman's three decades of research on the form and functions of the brain and spinal cord. Building on his experience as a neuroscientist studying model systems as primitive as eels and as a neurologist studying humans, Waxman discusses a wide variety of topics, including the design principles that optimize neural function; molecular and cellular substrates of behavior; the role of glial cells in the brain; the molecular basis for pain; plasticity in the brain and spinal cord; strategies for promoting functional recovery in disorders such as multiple sclerosis, spinal cord injury, and stroke; and prospects for rebuilding the brain and spinal cord. The pieces provide example after example of the elegance of design of the nervous system, of the intricate interplay between structure and function in health and disease, and of the rich borderland between neuroscience and neurology.

Author : Michael S. Gazzaniga
Publisher : Springer
Page : 413 pages
File Size : 40,5 Mb
Release : 2014-11-14
Category : Medical
ISBN : 9781489921772

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Handbook of Cognitive Neuroscience by Michael S. Gazzaniga Pdf

Author : Rainer Greger,Uwe Windhorst
Publisher : Springer Science & Business Media
Page : 2478 pages
File Size : 46,7 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9783642609466

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Comprehensive Human Physiology by Rainer Greger,Uwe Windhorst Pdf

Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.

Author : Library of Congress. Copyright Office
Publisher : Copyright Office, Library of Congress
Page : 1482 pages
File Size : 44,8 Mb
Release : 1977
Category : Copyright
ISBN : STANFORD:36105119498454

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Catalog of Copyright Entries. Third Series by Library of Congress. Copyright Office Pdf

Author : Alwyn Scott
Publisher : Routledge
Page : 1107 pages
File Size : 53,9 Mb
Release : 2006-05-17
Category : Reference
ISBN : 9781135455583

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Encyclopedia of Nonlinear Science by Alwyn Scott Pdf

In 438 alphabetically-arranged essays, this work provides a useful overview of the core mathematical background for nonlinear science, as well as its applications to key problems in ecology and biological systems, chemical reaction-diffusion problems, geophysics, economics, electrical and mechanical oscillations in engineering systems, lasers and nonlinear optics, fluid mechanics and turbulence, and condensed matter physics, among others.

Author : Fred Snell
Publisher : Elsevier
Page : 367 pages
File Size : 53,6 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323153959

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Progress in Theoretical Biology by Fred Snell Pdf

Progress in Theoretical Biology, Volume 2, brings together the significant and timely theoretical developments in particular areas of biology in a critical and synthetic manner. It is concerned with a field which has emerged as an identifiable subdiscipline of the biological sciences. This emergence and recognition signify that biological science has evolved from its initial stage of description and classification into the adolescence of transformation to the quantitative. The book's opening chapter develops a theory that uses a new generalization of statistical mechanics to provide a basis for understanding how the microscopic behavior of nonliving parts can generate the macroscopic appearance of a living aggregate. The subsequent chapters discuss theoretical methods in systematic and evolutionary studies; the theory of neural masses; the design of chemical reaction systems; cooperative processes in biological systems; and the organization of motor systems. This book is intended for the modern biological scientist as well as for the physical scientist who is inquisitive of the ways of the most complex of all processes.

Author : Leslie A. Pray,Institute of Medicine,Ann L. Yaktine,Food and Nutrition Board,Board on Health Sciences Policy,Diana E. Pankevich,Planning Committee for a Workshop on Potential Health Hazards Associated with Consumption of Caffeine in Food and Dietary Supplements
Publisher : Unknown
Page : 0 pages
File Size : 48,9 Mb
Release : 2014
Category : Health & Fitness
ISBN : 0309297494

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Caffeine in Food and Dietary Supplements by Leslie A. Pray,Institute of Medicine,Ann L. Yaktine,Food and Nutrition Board,Board on Health Sciences Policy,Diana E. Pankevich,Planning Committee for a Workshop on Potential Health Hazards Associated with Consumption of Caffeine in Food and Dietary Supplements Pdf

Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

Author : P. Michael Conn
Publisher : Academic Press
Page : 776 pages
File Size : 53,9 Mb
Release : 2016-09-28
Category : Medical
ISBN : 9780128025963

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Conn's Translational Neuroscience by P. Michael Conn Pdf

Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

Author : Marcus Jacobson
Publisher : Springer Science & Business Media
Page : 394 pages
File Size : 46,5 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489917812

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Foundations of Neuroscience by Marcus Jacobson Pdf

The author makes a unique contribution to the field by discussing the history and philosophy of the neurosciences, and then developing critical approaches which integrate techniques, theory, and ethics. Taken as a whole, Jacobson's work will provide a coherent and humane framework for future research programs. The paperback edition of this highly successful text, first published in 1993, is now available! The author brings the ethics of neuroscience into a closer relationship with empirical research. Covering the field's history, philosophy, theories, and techniques, this volume provides the necessary moral and ethical framework to evaluate neuroscience research.