Mass Spectrometry For The Novice

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Mass Spectrometry for the Novice

Author : John Greaves
Publisher : CRC Press
Page : 310 pages
File Size : 51,9 Mb
Release : 2017-06-29
Category : Electronic
ISBN : 1138410217

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Mass Spectrometry for the Novice by John Greaves Pdf

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments. Mass Spectrometry for the Novice provides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques.The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites.Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entr�to mass spectrometry. A CD-ROM with selected figures and cartoons is included.

Mass Spectrometry for the Novice

Author : John Greaves,John Roboz
Publisher : CRC Press
Page : 309 pages
File Size : 45,5 Mb
Release : 2013-10-16
Category : Medical
ISBN : 9781420094206

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Mass Spectrometry for the Novice by John Greaves,John Roboz Pdf

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers

Mass Spectrometry for the Novice

Author : John Greaves,John Roboz
Publisher : CRC Press
Page : 312 pages
File Size : 50,9 Mb
Release : 2013-10-16
Category : Science
ISBN : 9781420094183

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Mass Spectrometry for the Novice by John Greaves,John Roboz Pdf

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments. Mass Spectrometry for the Novice provides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques. The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites. Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entrée to mass spectrometry. A CD-ROM with selected figures and cartoons is included.

Mass Spectrometry

Author : Edmond de Hoffmann,Vincent Stroobant
Publisher : John Wiley & Sons
Page : 502 pages
File Size : 54,5 Mb
Release : 2013-04-03
Category : Science
ISBN : 9781118681947

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Mass Spectrometry by Edmond de Hoffmann,Vincent Stroobant Pdf

The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.

A Beginner's Guide to Mass Spectral Interpretation

Author : Terrence A. Lee
Publisher : John Wiley & Sons
Page : 210 pages
File Size : 49,5 Mb
Release : 1998-02-04
Category : Science
ISBN : 0471976296

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A Beginner's Guide to Mass Spectral Interpretation by Terrence A. Lee Pdf

Die Massenspektrometrie ist eine der wenigen Techniken, mit denen man organische Verbindungen eindeutig identifizieren kann. Dieses Buch behandelt die Interpretation von Massenspektren organischer Verbindungen, und zwar auf einem für Studienanfänger und Fortgeschrittene geeigneten Niveau. Die verschiedenen organischen Verbindungen werden in einzelnen Kapiteln besprochen, wobei der Schwerpunkt auf einem verbindungsspezifischen Ansatz zur Interpretation von Massenspektren liegt. Einfach und verständlich geschrieben mit mehr als 120 repräsentativen Spektren, ist dieses Werk speziell für Studierende im 2. und 3. Studienjahr sowie für Neulinge auf diesem Gebiet gedacht. (01/98)

A Beginner's Guide to Mass Spectral Interpretation

Author : Terrence A. Lee
Publisher : Unknown
Page : 208 pages
File Size : 46,8 Mb
Release : 1998-02-02
Category : Science
ISBN : STANFORD:36105023478279

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A Beginner's Guide to Mass Spectral Interpretation by Terrence A. Lee Pdf

This book, the first to be dedicated solely to interpretation of electron impact mass spectra, is a logical, step-by-step guide to identification of organic compounds by mass spectrometry. The book is organized into chapters covering the major types of organic compounds, including alcohols, acids and esters, aldehydes and ketones, ethers, hydrocarbons, halogenated compounds, amines and amides, and sulfur-containing compounds. In each chapter, the mechanisms of the major fragmentation pathways are discussed, with reference to several simple sample compounds. By teaching the user to recognize typical fragmentations, the book removes the need to search databases, often limited, of electronic spectra. Key features of the book include: 200 representative spectra of common organic compounds Functional group approach to mass spectra interpretation Appendix of ?unknown? spectra with step-by-step guide to identification This book is a must for anyone who needs to identify organic molecules by mass spectrometry but does not need to know the detailed workings of a mass spectrometer.

A Practical Guide to Implementing Clinical Mass Spectrometry Systems

Author : Neil Leaver
Publisher : ILM Publications
Page : 97 pages
File Size : 55,9 Mb
Release : 2011
Category : Medical
ISBN : 9781906799106

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A Practical Guide to Implementing Clinical Mass Spectrometry Systems by Neil Leaver Pdf

Mass spectrometry is becoming increasingly popular in the field of therapeutic drug monitoring. The aim of this publication is to provide practical guidance for laboratories on the implementation of mass spectrometry into a clinical service where there might be limited expertise in the technique. This guidance is the author's personal recommendation based on over ten years' experience of clinical mass spectrometry. Throughout the text, examples are given to illustrate issues that a clinical laboratory might encounter. While some examples relate to the field of immunosuppressive drug monitoring, the issues are common and relevant to any clinical application. The guidance provided is also applicable to instrumentation made by any manufacturer. This practical guide covers instrument selection through business planning to installation, risk management and validation, and includes suggestions for future prospects for this developing field.

Mass Spectrometry for Biotechnology

Author : Gary Siuzdak
Publisher : Elsevier
Page : 179 pages
File Size : 49,7 Mb
Release : 1996-02-12
Category : Science
ISBN : 9780080535845

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Mass Spectrometry for Biotechnology by Gary Siuzdak Pdf

If you investigate biological systems and might use mass spectrometry in your research but need to know more about it, this book is for you. It introduces the fundamental concepts of mass spectrometry and how mass spectrometers work. It also presents recent advancements particularly interesting to bio-researchers in an easy-to-understand manner that does not require extensive background in chemistry, math, or physics. Glossary of basic terms Abundant illustrations Examples of applications Practical tips on using mass spectrometric techniques Useful for peptide, protein, oligonucleotide, and carbohydrate analysis Simplified description of mass spectrometry including: Matrix-Assisted Laser Desorption/Ionization (MALDI) Electrospray Ionization (ESI) Fast Atom/Ion Bombardment (FAB)

Gas Chromatography and Mass Spectrometry: A Practical Guide

Author : O. David Sparkman,Zelda Penton,Fulton G. Kitson
Publisher : Academic Press
Page : 632 pages
File Size : 43,6 Mb
Release : 2011-05-17
Category : Science
ISBN : 0080920152

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Gas Chromatography and Mass Spectrometry: A Practical Guide by O. David Sparkman,Zelda Penton,Fulton G. Kitson Pdf

The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated. Covers the practical instruction necessary for successful operation of GC/MS equipment Reviews the latest advances in instrumentation, ionization methods, and quantitation Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner A true benchtop reference A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS) Quick References to data interpretation Ready source for information on new analyses

Mass Spectrometry Basics

Author : Christopher G. Herbert,Robert A.W. Johnstone
Publisher : CRC Press
Page : 474 pages
File Size : 48,9 Mb
Release : 2002-06-26
Category : Science
ISBN : 9781420040340

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Mass Spectrometry Basics by Christopher G. Herbert,Robert A.W. Johnstone Pdf

Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides

Practical Mass Spectrometry

Author : Brian S. Middleditch
Publisher : Springer Science & Business Media
Page : 394 pages
File Size : 54,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461329824

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Practical Mass Spectrometry by Brian S. Middleditch Pdf

It has been estimated that more than 8090 of the world's scientists who have ever lived are still alive today. It would not be unreasonable to suggest that more than 95% of those who have ever used a mass spectrometer are not only alive but are still actively employed. Most have never had any formal training in the subject since, with a few notable exceptions, universities have only recently begun to offer courses in mass spectrometry. We have written this book for the student of modern mass spectro metry: it is for the novice who wished to know what the instruments can do and how the techniques can be applied. There are other books on the market which delve into the history of mass spectrometry and go deeply into the mathematical theory and instrumentation. There are yet more books which guide one through the art of interpreting spectra. We have deliberately avoided these topics so that the reader is confronted only with the basic principles and is allowed a taste of the applications. One of the best methods of deVeloping a useful textbook is to teach a course based upon its content. This is what we did. We met in Houston in 1976 to teach a course on "Perspectives in Mass Spectrometry" and to coordinate our writing. The authors of five of the chapters met again in St.

Mass Spectrometry

Author : Marek Smoluch,Giuseppe Grasso,Piotr Suder,Jerzy Silberring
Publisher : John Wiley & Sons
Page : 361 pages
File Size : 48,8 Mb
Release : 2019-06-17
Category : Science
ISBN : 9781119377344

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Mass Spectrometry by Marek Smoluch,Giuseppe Grasso,Piotr Suder,Jerzy Silberring Pdf

Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule. Provides a description of mass spectrometry basics, applications and perspectives of the technique Oriented to a broad audience with limited or basic knowledge in mass spectrometry instrumentation, theory, and its applications in order to enhance their competence in this field Covers all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS with special attention to application of various methodologies and data interpretation Includes a list of key terms, and test questions, for easier and faster understanding of the material Mass Spectrometry: An Applied Approach is highly recommended for advanced students, young scientists, and anyone involved in a field that utilizes the technique.

Practical Guide to ICP-MS

Author : Robert Thomas
Publisher : CRC Press
Page : 323 pages
File Size : 40,9 Mb
Release : 2003-12-11
Category : Science
ISBN : 9780824758837

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Practical Guide to ICP-MS by Robert Thomas Pdf

Written by a field insider with more than 20 years of experience in the development and application of atomic spectroscopy instrumentation, the Practical Guide to ICP-MS offers key concepts and guidelines in a reader-friendly format that is superb for those with limited knowledge of the technique. This reference discusses the fundamental principles, analytical advantages, practical capabilities, and overall benefits of ICP-MS. It presents the most important selection criteria when evaluating commercial ICP-MS equipment and the most common application areas of ICP-MS such as the environmental, semiconductor, geochemical, clinical, nuclear, food, metallurgical, and petrochemical industries.

Introduction to Mass Spectrometry

Author : J. Throck Watson,O. David Sparkman
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 47,5 Mb
Release : 2013-07-09
Category : Science
ISBN : 9781118681589

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Introduction to Mass Spectrometry by J. Throck Watson,O. David Sparkman Pdf

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Comprehensive Environmental Mass Spectrometry

Author : Albert Lebedev
Publisher : ILM Publications
Page : 544 pages
File Size : 44,7 Mb
Release : 2012
Category : Science
ISBN : 9781906799120

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Comprehensive Environmental Mass Spectrometry by Albert Lebedev Pdf

"In full colour throughout, this book describes the power of mass spectrometry in resolving environmental issues, demonstrating how real-world complex problems can be solved in a simple and elegant way."--Worldcat.