Mathematical Models For Therapeutic Approaches To Control Hiv Disease Transmission

Author : Priti Kumar Roy
Publisher : Springer
Page : 213 pages
File Size : 50,5 Mb
Release : 2015-12-08
Category : Mathematics
ISBN : 9789812878526

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Mathematical Models for Therapeutic Approaches to Control HIV Disease Transmission by Priti Kumar Roy Pdf

The book discusses different therapeutic approaches based on different mathematical models to control the HIV/AIDS disease transmission. It uses clinical data, collected from different cited sources, to formulate the deterministic as well as stochastic mathematical models of HIV/AIDS. It provides complementary approaches, from deterministic and stochastic points of view, to optimal control strategy with perfect drug adherence and also tries to seek viewpoints of the same issue from different angles with various mathematical models to computer simulations. The book presents essential methods and techniques for students who are interested in designing epidemiological models on HIV/AIDS. It also guides research scientists, working in the periphery of mathematical modeling, and helps them to explore a hypothetical method by examining its consequences in the form of a mathematical modelling and making some scientific predictions. The model equations, mathematical analysis and several numerical simulations that are presented in the book would serve to reveal the consequences of the logical structure of the disease transmission, quantitatively as well as qualitatively. One of the chapters introduces the optimal control approach towards the mathematical models, describing the optimal drug dosage process that is discussed with the basic deterministic models dealing with stability analysis. Another one chapter deals with the mathematical analysis for the perfect drug adherence for different drug dynamics during the treatment management. The last chapter of the book consists the stochastic approach to the disease dynamics on HIV/AIDS. This method helps to move the disease HIV/AIDS to extinction as the time to increase. This book will appeal to undergraduate and postgraduate students, as well as researchers, who are studying and working in the field of bio-mathematical modelling on infectious diseases, applied mathematics, health informatics, applied statistics and qualitative public health, etc. Social workers, who are working in the field of HIV, will also find the book useful for complements.

Author : Abba B. Gumel,Suzanne Lenhart
Publisher : American Mathematical Soc.
Page : 286 pages
File Size : 47,9 Mb
Release : 2010
Category : Mathematics
ISBN : 9780821843840

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Modeling Paradigms and Analysis of Disease Transmission Models by Abba B. Gumel,Suzanne Lenhart Pdf

This volume stems from two DIMACS activities, the U.S.-Africa Advanced Study Institute and the DIMACS Workshop, both on Mathematical Modeling of Infectious Diseases in Africa, held in South Africa in the summer of 2007. It contains both tutorial papers and research papers. Students and researchers should find the papers on modeling and analyzing certain diseases currently affecting Africa very informative. In particular, they can learn basic principles of disease modeling and stability from the tutorial papers where continuous and discrete time models, optimal control, and stochastic features are introduced.

Author : D. M. Basavarajaiah,Bhamidipati Narasimha Murthy
Publisher : Springer Nature
Page : 340 pages
File Size : 42,6 Mb
Release : 2019-11-29
Category : Medical
ISBN : 9789811501517

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HIV Transmission by D. M. Basavarajaiah,Bhamidipati Narasimha Murthy Pdf

This book presents models describing HIV transmission rates at population level, discussing the main statistical methods and analytical interventions. It also assesses the practical applicability of the various modelling techniques, offering readers insights into what methods are available and, more importantly, when they should be used to address HIV transmission at global level. The book includes realistic simulation models fitted to clarify the rate of HIV mother-to-child transmission (HIV MTCT), and substantiates the conclusions that can be drawn as well as the appropriate time for making global-level clinical decisions concerning people living with HIV/AIDS (PLHIVs). Intended for students, academics and researchers, the book offers more than just an introduction to the topic – it also features in-depth, yet easy-to-understand, descriptions of a new mathematical/statistical HIV mother-to-child transmission model, making it a useful resource for clinicians, public health workers and policymakers involved in implementing HIV-prevention programmes at national /global level.

Author : Khalid Hattaf,Hemen Dutta
Publisher : Springer Nature
Page : 348 pages
File Size : 53,7 Mb
Release : 2020-07-30
Category : Technology & Engineering
ISBN : 9783030498962

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Mathematical Modelling and Analysis of Infectious Diseases by Khalid Hattaf,Hemen Dutta Pdf

This book discusses significant research and study topics related to mathematical modelling and analysis of infectious diseases. It includes several models and modelling approaches with different aims, such as identifying and analysing causes of occurrence and re-occurrence, causes of spreading, treatments and control strategies. A valuable resource for researchers, students, educators, scientists, professionals and practitioners interested in gaining insights into various aspects of infectious diseases using mathematical modelling and mathematical analysis, the book will also appeal to general readers wanting to understand the dynamics of various diseases and related issues. Key Features Mathematical models that describe population prevalence or incidence of infectious diseases Mathematical tools and techniques to analyse data on the incidence of infectious diseases Early detection and risk estimate models of infectious diseases Mathematical models that describe the transmission of infectious diseases and analyse data Dynamical analysis and control strategies for infectious diseases Studies comparing the utility of particular models in describing infected diseases-related issues such as social, health and economic

Author : Priti Kumar Roy,Abhirup Datta
Publisher : Springer
Page : 89 pages
File Size : 53,8 Mb
Release : 2019-07-18
Category : Mathematics
ISBN : 9789811390203

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Mathematical Models for Therapeutic Approaches to Control Psoriasis by Priti Kumar Roy,Abhirup Datta Pdf

This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production of keratinocyte cell population, the book is intended for researchers and scientists in the field of applied mathematics, health informatics, applied statistics and qualitative public health, as well as bio-mathematicians interested in the mathematical modeling of autoimmune diseases like psoriasis.

Author : Fred Brauer,Carlos Castillo-Chavez
Publisher : SIAM
Page : 279 pages
File Size : 48,5 Mb
Release : 2013-02-07
Category : Mathematics
ISBN : 9781611972412

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Mathematical Models for Communicable Diseases by Fred Brauer,Carlos Castillo-Chavez Pdf

A self-contained and comprehensive guide to the mathematical modeling of disease transmission, appropriate for graduate students.

Author : W. Y. Tan,Hulin Wu
Publisher : World Scientific
Page : 610 pages
File Size : 41,8 Mb
Release : 2005
Category : Mathematics
ISBN : 9789812561398

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Deterministic and Stochastic Models of AIDS Epidemics and HIV Infections with Intervention by W. Y. Tan,Hulin Wu Pdf

- Only book on extensive, deterministic models, statistic models, stochastic models and state space models and statistical methods for HIV epidemic involving IV drug usage and HIV epidemic in homosexual populations. - Provides most recent biological insights into HIV pathogenesis and HIV kinetics at the cellular level, and illustrates how to build up mathematical models based on these biological insights. - Only publication that provides in-depth analysis of HAART treatment protocols and discusses possible improvements to the HAART protocol. The book also provides connection between pharmacokinetics with treatment in HIV-infected individuals.

Author : Ron Brookmeyer,Mitchell H. Gail
Publisher : Oxford University Press
Page : 374 pages
File Size : 51,9 Mb
Release : 1994-01-06
Category : Medical
ISBN : 9780199748747

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AIDS Epidemiology by Ron Brookmeyer,Mitchell H. Gail Pdf

AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic. This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project pediatric AIDS incidence -- is not available in any other work.

Author : Fred Brauer,Carlos Castillo-Chavez,Zhilan Feng
Publisher : Springer Nature
Page : 628 pages
File Size : 53,6 Mb
Release : 2019-10-10
Category : Mathematics
ISBN : 9781493998289

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Mathematical Models in Epidemiology by Fred Brauer,Carlos Castillo-Chavez,Zhilan Feng Pdf

The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of disease transmission models. It includes (i) an introduction to the main concepts of compartmental models including models with heterogeneous mixing of individuals and models for vector-transmitted diseases, (ii) a detailed analysis of models for important specific diseases, including tuberculosis, HIV/AIDS, influenza, Ebola virus disease, malaria, dengue fever and the Zika virus, (iii) an introduction to more advanced mathematical topics, including age structure, spatial structure, and mobility, and (iv) some challenges and opportunities for the future. There are exercises of varying degrees of difficulty, and projects leading to new research directions. For the benefit of public health professionals whose contact with mathematics may not be recent, there is an appendix covering the necessary mathematical background. There are indications which sections require a strong mathematical background so that the book can be useful for both mathematical modelers and public health professionals.

Author : Jummy David,Jianhong Wu
Publisher : Springer Nature
Page : 324 pages
File Size : 43,9 Mb
Release : 2023-12-30
Category : Mathematics
ISBN : 9783031408052

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Mathematics of Public Health by Jummy David,Jianhong Wu Pdf

This volume addresses SDG 3 from a mathematical standpoint, sharing novel perspectives of existing communicable disease modelling technologies of the next generation and disseminating new developments in modelling methodologies and simulation techniques. These methodologies are important for training and research in communicable diseases and can be applied to other threats to human health. The contributions contained in this collection/book cover a range of modelling techniques that have been and may be used to support decision-making on critical health related issues such as: Resource allocation Impact of climate change on communicable diseases Interaction of human behaviour change, and disease spread Disease outbreak trajectories projection Public health interventions evaluation Preparedness and mitigation of emerging and re-emerging infectious diseases outbreaks Development of vaccines and decisions around vaccine allocation and optimization The diseases and public health issues in this volume include, but are not limited to COVID-19, HIV, Influenza, antimicrobial resistance (AMR), the opioid epidemic, Lyme Disease, Zika, and Malaria. In addition, this volume compares compartmental models, agent-based models, machine learning and network. Readers have an opportunity to learn from the next generation perspective of evolving methodologies and algorithms in modelling infectious diseases, the mathematics behind them, the motivation for them, and some applications to supporting critical decisions on prevention and control of communicable diseases. This volume was compiled from the weekly seminar series organized by the Mathematics for Public Health (MfPH) Next Generation Network. This network brings together the next generation of modellers from across Canada and the world, developing the latest mathematical models, modeling methodologies, and analytical and simulation tools for communicable diseases of global public health concerns. The weekly seminar series provides a unique forum for this network and their invited guest speakers to share their perspectives on the status and future directions of mathematics of public health.

Author : J. C. Jager,E. Joost Ruitenberg
Publisher : Oxford University Press, USA
Page : 167 pages
File Size : 48,9 Mb
Release : 1988
Category : Medical
ISBN : 0192617451

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Statistical Analysis and Mathematical Modelling of AIDS by J. C. Jager,E. Joost Ruitenberg Pdf

In the worldwide fight against the AIDS epidemic, the ability to predict the number and social impact of future cases plays a vital role. The choice of control strategies, public health decisions, and the evaluation of possible interventions depend on having such information that is accurate and reliable. This book is devoted to the statistical analysis of basic data on the spread of AIDS and the mathematical modelling of the transmission and spread of the human immunodeficiency virus (HIV) which causes the disease. Such techniques take into account medical, psychosocial, behavioral and economic factors, and can help to integrate this information into an efficient methodology for the estimation of future needs and how to meet them. In addition to AIDS specialists, the studies here will be valuable to all those involved in public health, epidemiology and the control of communicable diseases.

Author : Priti Kumar Roy,Xianbing Cao,Xue-Zhi Li,Pratulananda Das,Satya Deo
Publisher : Springer Nature
Page : 518 pages
File Size : 49,5 Mb
Release : 2020-03-10
Category : Mathematics
ISBN : 9789811504228

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Mathematical Analysis and Applications in Modeling by Priti Kumar Roy,Xianbing Cao,Xue-Zhi Li,Pratulananda Das,Satya Deo Pdf

This book collects select papers presented at the “International Conference on Mathematical Analysis and Application in Modeling,” held at Jadavpur University, Kolkata, India, on 9–12 January 2018. It discusses new results in cutting-edge areas of several branches of mathematics and applications, including analysis, topology, dynamical systems (nonlinear, topological), mathematical modeling, optimization and mathematical biology. The conference has emerged as a powerful forum, bringing together leading academics, industry experts and researchers, and offering them a venue to discuss, interact and collaborate in order to stimulate the advancement of mathematics and its industrial applications.

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 47,9 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Author : Anonim
Publisher : Unknown
Page : 832 pages
File Size : 53,8 Mb
Release : 2002
Category : Electronic
ISBN : OCLC:874323342

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Oxford Textbook of Public Health by Anonim Pdf

Author : National Research Council and Institute of Medicine,Institute of Medicine,Panel on Needle Exchange and Bleach Distribution Programs
Publisher : National Academies Press
Page : 352 pages
File Size : 43,7 Mb
Release : 1995-09-14
Category : Medical
ISBN : 9780309176217

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Preventing HIV Transmission by National Research Council and Institute of Medicine,Institute of Medicine,Panel on Needle Exchange and Bleach Distribution Programs Pdf

This volume addresses the interface of two major national problems: the epidemic of HIV-AIDS and the widespread use of illegal injection drugs. Should communities have the option of giving drug users sterile needles or bleach for cleaning needs in order to reduce the spread of HIV? Does needle distribution worsen the drug problem, as opponents of such programs argue? Do they reduce the spread of other serious diseases, such as hepatitis? Do they result in more used needles being carelessly discarded in the community? The panel takes a critical look at the available data on needle exchange and bleach distribution programs, reaches conclusions about their efficacy, and offers concrete recommendations for public policy to reduce the spread of HIV/AIDS. The book includes current knowledge about the epidemiologies of HIV/AIDS and injection drug use; characteristics of needle exchange and bleach distribution programs and views on those programs from diverse community groups; and a discussion of laws designed to control possession of needles, their impact on needle sharing among injection drug users, and their implications for needle exchange programs.