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Mechanisms And Novel Therapies In Graves Orbitopathy Current Update Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Mechanisms And Novel Therapies In Graves Orbitopathy Current Update book. This book definitely worth reading, it is an incredibly well-written.
Author : Kelvin Kam-Lung Chong,Ilaria Muller,Huifang Zhou,Marian Elizabeth Ludgate
Publisher : Frontiers Media SA
Page : 204 pages
File Size : 52,9 Mb
Release : 2022-05-24
Category : Medical
ISBN : 9782889762071
Author : W.M. Wiersinga,G.J. Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 302 pages
File Size : 55,8 Mb
Release : 2010-08-17
Category : Medical
ISBN : 9783805595322
The significant progress in the understanding of the pathogenesis and the treatment of Graves’ orbitopathy (GO) has warranted a second edition of this book within three years of the first. Now also fully incorporated is the EUGOGO consensus statement on management of GO, which since has been accepted worldwide as a useful guideline. Furthermore all chapters have been thoroughly updated. Subjects covered include the pathology of GO and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Two new chapters have been added: one describing the socioeconomic impact of the disease and the other outlining the Amsterdam Declaration on Graves’ Orbitopathy. The successful question-and-answer format facilitates its use as a reference guide for medical practitioners and surgeons working in the fields of ophthalmology, internal medicine, endocrinology, pediatrics, immunology, as well as otorhinolaryngology.
Author : A. Pinchera
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309451
In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.
Author : Paolo Vitti,Laszlo Hegedüs
Publisher : Springer
Page : 770 pages
File Size : 53,7 Mb
Release : 2018-09-09
Category : Medical
ISBN : 3319450123
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.
Author : Wilmar M. Wiersinga,George Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 275 pages
File Size : 47,7 Mb
Release : 2007
Category : Medical
ISBN : 9783805583428
In recent years, close interdisciplinary cooperation of numerous international experts, both clinicians and basic scientists, within the European Group of Graves' orbitopathy (EUGOGO) has yielded much valuable progress and new information, which this publication brings together. Subjects covered include the pathology of Graves' orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Stressing the current management of thyroid eye disease, this book offers medical practitioners a thorough overview of associated changes in the eyes of patients with GO. Therefore, this publication is an essential resource for ophthalmologists, internists, endocrinologists, pediatricians, immunologists, specialists in nuclear medicine, neuroradiologists and radiotherapists, specialists in laboratory medicine and pathology, otorhinolaryngologists, orbital and neurosurgeons as well as oral and maxillofacial surgeons.
Author : W.M. Wiersinga,G.J. Kahaly
Publisher : Karger Medical and Scientific Publishers
Page : 378 pages
File Size : 44,7 Mb
Release : 2017-08-21
Category : Medical
ISBN : 9783318060850
Ten years ago, the first edition of Graves’ Orbitopathy: A Multidisciplinary Approach was published. Since then, the book has become very popular and much has happened in the field to warrant a third edition. What has not changed is the successful and attractive question-and-answer format of the book. In the 3rd, revised and expanded edition, new chapters have been added on co-morbidity, local treatment modalities, novel immunosuppressive therapy, detailed protocols, and questions frequently asked by patients. All chapters of the previous edition have been thoroughly updated. Subjects covered then include the pathology of Graves’ Orbitopathy (GO) and the controversial views on its pathogenesis; assessment of changes using reliable measuring techniques; medical management of GO including established and alternative treatment options; technical explanations and illustrations of various surgical procedures; and finally, the molecular, immunologic, and clinical aspects of this complex disorder. Additionally, ample consideration is given to the new 2016 ETA/EUGOGO guidelines on the management of GO.
Author : Stefan Offermanns,W. Rosenthal
Publisher : Springer Science & Business Media
Page : 1515 pages
File Size : 41,7 Mb
Release : 2008-08-14
Category : Medical
ISBN : 9783540389163
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Author : Fumito Ito,Marc Ernstoff
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 51,8 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9780323549509
Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.
Author : David Hilton-Jones,Martin R. Turner,Martin Turner
Publisher : Oxford Textbooks in Clinical N
Page : 399 pages
File Size : 47,5 Mb
Release : 2014
Category : Medical
ISBN : 9780199698073
'The Oxford Textbook of Neuromuscular Disorders' covers the scientific basis, clinical diagnosis, and treatment of neuromuscular disorders, with a particular focus on the most clinically relevant disorders
Author : Markus Luster,Leonidas H. Duntas,Leonard Wartofsky
Publisher : Springer
Page : 770 pages
File Size : 54,6 Mb
Release : 2019-01-08
Category : Medical
ISBN : 9783319721026
This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.
Author : Bipasha Mukherjee,Hunter Yuen
Publisher : Springer
Page : 490 pages
File Size : 51,5 Mb
Release : 2016-12-15
Category : Medical
ISBN : 9788132218074
This handbook on orbital, lacrimal and eyelid emergencies deals with such situations in a practical manner guiding the ophthalmologists in accurate handling and making them more proficient and confident in managing vision and life-threatening emergencies. With 51 chapters and more than 350 images, this book covers all the eye emergencies that generalist and specialist ophthalmologists can expect to come across in their day to day practices. It can be argued that the orbit can no more be called ‘Pandora’s Box’ because of the unpredictable nature of its contents. This perception has changed over the years due to the advent of improved diagnostic, in particular, imaging techniques. However, since medical residency provides very little exposure to orbital and adnexal disorders, most clinicians are inexperienced and unsure about their management. Facing an emergency situation where improper management can rapidly worsen the condition leading to blindness or even death of the patient is every ophthalmologist’s nightmare. The emergent nature of these conditions does not always provide for a leeway to refer these patients to an orbit and oculoplasty specialist, who are few and far between. By the time the patient reaches his destination, his vision maybe irrevocably lost. The legal implications of such mismanagement can be significant too. This book is a quick and essential resource to manage and refer eye emergencies with confidence.
Author : N.K. Agrawal
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 53,5 Mb
Release : 2020-04-08
Category : Medical
ISBN : 9781789859638
The thyroid gland is a commonly diseased endocrine organ of human body. The disorders affecting the thyroid gland are varied but are very much amenable to treatment. The enlargement of the thyroid is termed goiter. It can affect the whole gland or only part of it. The disease is perplexing but in-depth knowledge of the pathophysiology helps in elucidating causes and thereby treating the disease. In this book, the diffuse and nodular goiter has been addressed as well as the functional abnormalities of the gland and its implications on the body are discussed in various chapters. The relevant updated information is included. To address a few of these current issues and recent updated information, authors have put in a lot of effort to organize the book.
Author : Raphaela Goldbach-Mansky,Betty Diamond
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 54,8 Mb
Release : 2023-03-31
Category : Medical
ISBN : 9782832519387
Author : Amanda D. Henderson,Andrew R. Carey
Publisher : Springer Nature
Page : 282 pages
File Size : 40,6 Mb
Release : 2021-06-25
Category : Medical
ISBN : 9783030741037
This book functions as a resource for providers who treat patients with neuro-ophthalmic conditions. Using an evidence-based approach to controversial management decisions, the material is presented in a digestible, case-based format. Divided into six sections, the book begins with an introduction to its framework, format, and purpose. Following this, sections two, three, and four discuss various optic neuropathies, ocular motility disorders, and transient visual symptoms. The concluding sections then address neuro-ophthalmic manifestations of pain, including migraine and post-concussive syndrome, and systemic diseases, such as giant cell arteritis. Each chapter focuses on cases that are historically complex, or which have undergone a recent shift in traditional management due to new scientific discoveries or newly available therapies. Controversies in Neuro-Ophthalmic Management presents essential, thorough information on management options and the data for their use to provide the best care for patients.
Author : Rebecca S. Bahn
Publisher : Springer
Page : 344 pages
File Size : 43,7 Mb
Release : 2015-03-31
Category : Medical
ISBN : 9781493925346
This indispensable volume is designed to facilitate the best possible physician–patient discussion on Graves’ disease by providing the most up-to-date evidence-based information in a clinically useful and patient-centric manner. Comprehensive and covering such topics as Professionalism and the Art of Patient-centric Thyroidology, the Immunopathogenesis of Graves’ Disease, and the Diagnosis and Management of Thyroid Storm, the book addresses all the important refinements in the treatment of Graves’ disease in recent years. These include new indications and contraindications for antithyroid drugs, improved approaches to radioactive iodine therapy, the development of novel surgical techniques, and a better understanding of the combined use of these modalities, among other developments. Also addressed are the advances in the treatment of GO, including the use of disease activity and severity assessments to inform management decisions and the completion of the first randomized controlled therapeutic trials. Developed by a renowned group of internationally respected authorities, Graves’ Disease: A Comprehensive Guide for Clinicians is a significant new reference that will be of great interest to all clinicians who treat this debilitating condition.