Thyroid Autoimmunity

Author : A. Pinchera
Publisher : Springer Science & Business Media
Page : 579 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309451

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Thyroid Autoimmunity by A. Pinchera Pdf

In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.

Author : Werner A. Scherbaum,Ulrich Bogner,Balthasar Weinheimer,G.F. Bottazzo
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642763014

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Autoimmune Thyroiditis by Werner A. Scherbaum,Ulrich Bogner,Balthasar Weinheimer,G.F. Bottazzo Pdf

Current knowledge relevant to the understanding of thyroid autoimmunity is summarized in this book. Some of the world's leading scientists in this field review recent data from four subject areas: immunogenetics, thyroid peroxidase as an antigen, environmental factors, and cytokines. Much ongoing and as yet unpublished work is described, especially in the discussion included after each article. This information is of particular interest since the body of knowledge in these fields is growing very rapidly. The book is based on a workshop in which researchers from 13 countries took part. One major aim was to raise controversial points and to develop ideas for their potential solution. At the workshop it became apparent that a great deal of the information given in textbooks is outdated. This is an important update for researchers who are interested in the above topics and in understanding the etiology and pathogenesis of thyroid autoimmunity.

Author : Pierre Carayon,Jean Ruf
Publisher : John Libbey Eurotext
Page : 388 pages
File Size : 54,9 Mb
Release : 1990
Category : Medical
ISBN : 086196277X

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Thyroperoxidase and Thyroid Autoimmunity by Pierre Carayon,Jean Ruf Pdf

Text in French & English. Proceedings of the International Symposium on Thyroperoxidase and Thyroid Autoimmunity, held in Marseille (France), 28-30 June 1990.

Author : Paul G. Walfish,Jack R. Wall,Robert Volpé
Publisher : Academic Press
Page : 476 pages
File Size : 40,5 Mb
Release : 2013-09-11
Category : Health & Fitness
ISBN : 9781483273983

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Autoimmunity and the Thyroid by Paul G. Walfish,Jack R. Wall,Robert Volpé Pdf

Autoimmunity and the Thyroid is a collection of papers presented at an International Satellite Meeting prior to the 7th International Congress of Endocrinology, held at the Mount Sinai Hospital, University of Toronto Medical School on June 29 and 30, 1984. The book provides presentations of participants relating to selected aspects of immune regulation and its role in autoimmune thyroid diseases. Concepts on humoral and cell-mediated immunity mechanisms in the pathogenesis of autoimmune thyroid disease are reviewed; important observations with promising clinical implications in terms of immunogenetics of Graves' and Hashimoto's diseases are presented; and selection of appropriate therapy for Graves' thyrotoxicosis, and the possibility of preventive immunosuppressive and ophthalmopathy therapy are discussed. Endocrinologists, physicians, pathologists, physiologists, and medical researchers will find the book interesting.

Author : Alessandro Antonelli,Salvatore Benvenga
Publisher : Frontiers Media SA
Page : 118 pages
File Size : 44,5 Mb
Release : 2018-11-02
Category : Electronic
ISBN : 9782889456253

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The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity by Alessandro Antonelli,Salvatore Benvenga Pdf

Autoimmune thyroid diseases (AITD) are T cell-mediated organ-specific autoimmune disorders resulting from an immune dysregulation leading to a thyroid immune attack (Antonelli and Benvenga). Graves’ disease and Hashimoto’s thyroiditis are the two main clinical presentations of AITD, and their clinical hallmarks are thyrotoxicosis and hypothyroidism, respectively. In many cases, AITD may be associated in the same patient with other organ-specific autoimmune attacks (such as in the case of type II autoimmune polyglandular syndrome, or type I diabetes, etc). Furthermore, AITD and thyroid function abnormalities have been frequently described in patients with systemic rheumatologic autoimmune diseases. Conversely, patients affected with the above mentioned autoimmune disorders are more frequently affected by AITD. In this Research Topic, constituted by nineteen papers, we review and discuss new evidence about the association of other autoimmune diseases in patients with AITD. Among other organ-specific autoimmune disorders, the associations of AITD with chronic autoimmune gastritis (Cellini et al.), vitiligo (Baldini E et al.), lichen (Guarneri et al.), psoriasis (Ruffilli et al.), myasthenia gravis (Lopomo and Berrih-Aknin) and glomerulopathies (Santoro et al.) have been treated. Also the associations of AITD, in systemic autoimmune diseases have been treated (as Sjögren’s syndrome, Baldini C et al.; systemic sclerosis, Fallahi et al.; systemic lupus erythematosus, Ferrari et al.; Antiphospholipid syndrome, Versini; sarcoidosis, Fazzi et al.; the autoimmune/inflammatory syndrome induced by adjuvants, Watad et al.; rheumatoid arthritis, Bliddal et al.; Hepatitis C Virus and mixed cryoglobulinemia, Ferri et al.; and, psoriathic arthritis, Ruffilli et al.). Furthermore peculiar aspects associated with post partum thyroiditis have been reviewed too (Di Bari et al., Le Donne et al.). The exact pathogenetic mechanisms underlying the above reported associations are not completely known. It has been hypothesized that the influence of genetic (Coppedè), and environmental factors (Antonelli and Benvenga), could lead to the onset of autoimmune phenomena in different organs in the same subject, characterized by predominance of a Th1 immune pattern at the beginning, and in the active phase of these disorders. In conclusion, an association of other autoimmune diseases in patients with thyroid autoimmunity has been shown, and this Research Topic provides an extensive update of the literature, and suggests interesting points for new investigations.

Author : Malgorzata Gabriela Wasniewska,Aneta Monika Gawlik,Tommaso Aversa
Publisher : Frontiers Media SA
Page : 118 pages
File Size : 47,7 Mb
Release : 2021-03-10
Category : Medical
ISBN : 9782889665860

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Autoimmune Thyroid Pathology - Specificity of the Pediatric Age by Malgorzata Gabriela Wasniewska,Aneta Monika Gawlik,Tommaso Aversa Pdf

Author : David C. Rayner,Brian Champion
Publisher : New York : Springer
Page : 236 pages
File Size : 53,7 Mb
Release : 1995-01-01
Category : Autoimmune thyroiditis
ISBN : 3540603514

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Thyroid Autoimmunity by David C. Rayner,Brian Champion Pdf

This book is about the autoimmune thyroid diseases. The perspective is broad, ranging from thyroid cell biology through experimental thyroid autoimmunity to the clinical aspects of human thyroid disease. Its multidisciplinary approach makes this book useful to both basic scientists and clinicians in immunology and endocrinology.

Author : Robert Volpé
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 43,7 Mb
Release : 1999-06-04
Category : Medical
ISBN : 9781592597048

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Autoimmune Endocrinopathies by Robert Volpé Pdf

Dr. Robert Volpé and his distinguished contributors comprehensively review the latest thinking about the theoretical, experimental, and clinical aspects of autoimmune endocrine disorders. These world-renowned experts examine the pathogenesis and immunogenetics of these diseases, discuss the role of sex hormones in autoimmunity, and elucidate the nature of autoantigens. They also provide clinical detail on a wide variety of autoimmune endocrinopathies, including autoimmune thyroid disease, Graves' ophthalmopathy and dermopathy, human insulin-dependent diabetes mellitus, and autoimmune adrenocortical failure. Postpartum autoimmune endocrine syndromes, autoimmune hypophysitis, and the polyglandular autoimmune syndromes are also discussed in detail. Comprehensive and authoritative, Autoimmune Endocrinopathies provides today's most up-to-date understanding of the etiology and pathogenesis of autoimmune endocrine diseases.

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 49,6 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Anonim
Publisher : Elsevier
Page : 568 pages
File Size : 42,7 Mb
Release : 2016-03-11
Category : Science
ISBN : 9780444634467

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Autoimmune Neurology by Anonim Pdf

Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Author : Robert Volpe'
Publisher : CRC Press
Page : 374 pages
File Size : 50,9 Mb
Release : 1990-10-05
Category : Medical
ISBN : 0849368499

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Autoimmune Diseases of the Endocrine System by Robert Volpe' Pdf

This book is a comprehensive, easy-to-read discussion of the organ-specific autoimmune endocrine diseases emphasizing new contributions and trends for research and management. It begins with a brief chapter introducing the general principles of immunology, followed by discussions covering topics such as immunogenetics and animal models and how they can be applied toward interpreting human autoimmune endocrine diseases, autoimmune thyroid diseases, insulin-dependent diabetes mellitus hypophysitis, and Addison's disease. The book also discusses future trends toward gaining an understanding of these disorders and possible therapeutic principles. It is well-illustrated and will prove to be a useful reference source for internists, endocrinologists, and postgraduate students interested in human autoimmune endocrine diseases.

Author : Yehuda Shoenfeld,Ricard Cervera,M. Eric Gershwin
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 48,8 Mb
Release : 2010-06-08
Category : Medical
ISBN : 9781603272858

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Diagnostic Criteria in Autoimmune Diseases by Yehuda Shoenfeld,Ricard Cervera,M. Eric Gershwin Pdf

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

Author : Takashi Akamizu,Jae Hoon Chung,Cesidio Giuliani,Rauf Latif,Giorgio Napolitano,Susanne Neumann
Publisher : Frontiers Media SA
Page : 126 pages
File Size : 41,5 Mb
Release : 2019-04-05
Category : Electronic
ISBN : 9782889458165

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TSH Receptor and Autoimmunity by Takashi Akamizu,Jae Hoon Chung,Cesidio Giuliani,Rauf Latif,Giorgio Napolitano,Susanne Neumann Pdf

The present Research Topic aims to provide updated reviews on TSH receptor structure and function, and its relationship with thyroid autoimmunity. Indeed, original reviews deal also with the pathogenesis of Graves' disease and its complications such as thyroid-associated opthalmopathy. Another issue that is addressed in this topic is the multifaceted nature of TSH receptor autoantibodies (TRAbs) and their role in the diagnosis and prognosis of Graves’ disease, with the most recent data on the clinical applications of TRAbs assays. Furthermore, the functional role of the TSH receptor in extrathyroidal tissues is discussed.

Author : Anthony P. Weetman
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 48,6 Mb
Release : 2007-12-26
Category : Medical
ISBN : 9781597455176

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Autoimmune Diseases in Endocrinology by Anthony P. Weetman Pdf

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

Author : A.P. Weetman
Publisher : Springer Science & Business Media
Page : 296 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401150446

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Endocrine Autoimmunity and Associated Conditions by A.P. Weetman Pdf

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.