Medicinal Chemistry Of Bioactive Natural Products

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Medicinal Chemistry of Bioactive Natural Products

Author : Xiao-Tian Liang,Wei-Shuo Fang
Publisher : John Wiley & Sons
Page : 482 pages
File Size : 54,8 Mb
Release : 2006-03-17
Category : Science
ISBN : 9780471739333

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Medicinal Chemistry of Bioactive Natural Products by Xiao-Tian Liang,Wei-Shuo Fang Pdf

Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents. Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research. Enhanced by examples with updated research results, the discussion covers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and its analogs * The antimalarial properties of the traditional Chinese medicine, Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer's disease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIV agents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and their structurally modified mimics

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : World Scientific
Page : 695 pages
File Size : 55,6 Mb
Release : 2012
Category : Science
ISBN : 9789814335379

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Bioactive Natural Products by Goutam Brahmachari Pdf

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Studies in Natural Products Chemistry

Author : Anonim
Publisher : Elsevier
Page : 540 pages
File Size : 53,5 Mb
Release : 2018-11-29
Category : Science
ISBN : 9780444641823

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Studies in Natural Products Chemistry by Anonim Pdf

Studies in Natural Products Chemistry, Volume 60 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Studies in Natural Products Chemistry

Author : Anonim
Publisher : Elsevier
Page : 470 pages
File Size : 48,5 Mb
Release : 2016-06-20
Category : Science
ISBN : 9780444636102

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Studies in Natural Products Chemistry by Anonim Pdf

Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the chemistry of bioactive natural products and their exciting new applications in the pharmaceutical industry Presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products Contains contributions by leading authorities in the field

Studies in Natural Products Chemistry

Author : Atta-ur-Rahman
Publisher : Elsevier
Page : 428 pages
File Size : 52,8 Mb
Release : 2017-07-18
Category : Science
ISBN : 9780444639356

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Studies in Natural Products Chemistry by Atta-ur-Rahman Pdf

Studies in Natural Products Chemistry, Volume 54, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores Offers an essential resource for researchers and engineers working in natural products and medicinal chemistry

Total Synthesis of Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : Elsevier
Page : 350 pages
File Size : 41,8 Mb
Release : 2019-04-27
Category : Science
ISBN : 9780081028230

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Total Synthesis of Bioactive Natural Products by Goutam Brahmachari Pdf

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products. Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules Outlines each step of the process in detail, with full experimental information supported by extensive schemes Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule

Bioactive Natural Products for Pharmaceutical Applications

Author : Dilipkumar Pal,Amit Kumar Nayak
Publisher : Springer Nature
Page : 862 pages
File Size : 49,6 Mb
Release : 2020-12-14
Category : Technology & Engineering
ISBN : 9783030540272

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Bioactive Natural Products for Pharmaceutical Applications by Dilipkumar Pal,Amit Kumar Nayak Pdf

This book covers the recent innovations relating to various bioactive natural products (such as alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, volatile oils, fixed oils, fats and waxes, proteins and peptides, vitamins, marine products, camptothecin, piperines, carvacrol, gedunin, GABA, ginsenosides) and their applications in the pharmaceutical fields related to academic, research and industry.

Studies in Natural Products Chemistry

Author : Atta-ur- Rahman
Publisher : Elsevier
Page : 994 pages
File Size : 51,7 Mb
Release : 2002-12-11
Category : Science
ISBN : 008052785X

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Studies in Natural Products Chemistry by Atta-ur- Rahman Pdf

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the 28th volume in the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance. The first paper presents over 100 compounds obtained from Broussonetia spp., and discusses biological activities. This is followed by similar contributions dealing with the genus Licania and Ginkgo biloba. Additional papers describe in detail a number of interesting and important natural compounds or structural classes: retinoids, tetramic acid metabolites, isoprenylated flavonoids, plant polyphenols, crocin, marcfortine and paraherquamide, acaricides, podolactones, triterpene glycosides and sulfur-containing marine compounds. An additional paper focuses on the antitumor activities of lipids, and a final contribution deals with natural product amelioration of cancer chemotherapy-induced adverse reactions.

Studies in Natural Products Chemistry

Author : Atta-ur- Rahman
Publisher : Elsevier
Page : 1269 pages
File Size : 55,7 Mb
Release : 2011-08-30
Category : Science
ISBN : 9780080458472

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Studies in Natural Products Chemistry by Atta-ur- Rahman Pdf

Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery. * Written by international authorities in the various fields of natural product chemistry * Contains 23 comprehensive articles covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases * Valuable source of information for research scientists and scholars in the field of new drug discovery

Pharmaceutical and Bioactive Natural Products

Author : David H. Attaway,Oskar R. Zaborsky
Publisher : Springer Science & Business Media
Page : 532 pages
File Size : 46,8 Mb
Release : 1993-03-31
Category : Science
ISBN : 0306441748

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Pharmaceutical and Bioactive Natural Products by David H. Attaway,Oskar R. Zaborsky Pdf

Biotechnology may be defined as the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services (Bullet al. , 1982, p. 21) or as any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop microorganisms for specific use (OTC, 1988). In line with these broad definitions we can consider marine biotechnology as the use of marine organisms or their constituents for useful purposes in a controlled fashion. This series will explore a range of scientific advances in support of marine biotechnology. It will provide information on advances in three categories: (1) basic knowledge, (2) ap plied research and development, and (3) commercial and institutional issues. We hope the presentation of the topics will generate interest and interaction among readers in the academic world, government, and industry. This first volume examines chemical and biological properties of some natural products that are useful or potentially useful in research and in the chemical and pharmaceutical industries. One chapter describes a system for producing such substances on a large scale. Biotechnology incorporates molecular biology in order to go beyond tradi tional biochemical technology such as the production of antibiotic drugs from bacterial cultures in bioreactors. Development of the technology for production of antibiotics in this way resulted from fundamental advances in chemistry, phar macology, microbiology, and biochemical engineering.

Studies in Natural Products Chemistry

Author : Atta-ur- Rahman
Publisher : Elsevier
Page : 544 pages
File Size : 40,5 Mb
Release : 2013-01-31
Category : Science
ISBN : 0444595309

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Studies in Natural Products Chemistry by Atta-ur- Rahman Pdf

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable resource for natural product and medicinal chemistry

Bioactive Natural products in Drug Discovery

Author : Joginder Singh,Vineet Meshram,Mahiti Gupta
Publisher : Springer Nature
Page : 733 pages
File Size : 44,7 Mb
Release : 2020-04-30
Category : Medical
ISBN : 9789811513947

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Bioactive Natural products in Drug Discovery by Joginder Singh,Vineet Meshram,Mahiti Gupta Pdf

This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Studies in Natural Products Chemistry

Author : Anonim
Publisher : Elsevier
Page : 434 pages
File Size : 47,6 Mb
Release : 2016-09-06
Category : Science
ISBN : 9780444636096

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Studies in Natural Products Chemistry by Anonim Pdf

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Bioactive Natural Products

Author : Goutam Brahmachari
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 42,7 Mb
Release : 2015-03-23
Category : Science
ISBN : 9783527337941

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Bioactive Natural Products by Goutam Brahmachari Pdf

Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Studies in Natural Products Chemistry

Author : Atta-ur-Rahman
Publisher : Elsevier
Page : 520 pages
File Size : 44,6 Mb
Release : 1988
Category : Science
ISBN : 9780128179048

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Studies in Natural Products Chemistry by Atta-ur-Rahman Pdf

Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores