Membrane Protein Lipid Interactions Physics And Chemistry In The Bilayer

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Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer

Jordi H. Borrell,Òscar Domènech,Kevin M.W. Keough
Membrane Protein Lipid Interactions Physics and Chemistry in the Bilayer Book PDF

Author : Jordi H. Borrell,Òscar Domènech,Kevin M.W. Keough
Publisher : Springer
Page : 116 pages
File Size : 50,6 Mb
Release : 2016-03-15
Category : Science
ISBN : 9783319302775

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Membrane Protein – Lipid Interactions: Physics and Chemistry in the Bilayer by Jordi H. Borrell,Òscar Domènech,Kevin M.W. Keough Pdf

This book has been conceives as a brief introduction to biomembranes physical chemistry for undergraduate students of sciences, and it is particularly dedicated to the lipid-protein membrane interactions. A general introduction is presented in Chapters 1 and 2. The following Chapters, 3 and 4, describe the most accepted theories on lipid-membrane protein interactions as well as the new experimental approaches, in particular, these arose from nano sciences as atomic for microscopy and single molecule force spectroscopy. The book emphasizes the relevance of physical parameters as the lateral surface pressure and the lipid curvature as actors for understanding the physicochemical properties of the biomembranes.

Protein-Lipid Interactions

C.Reyes Mateo,Javier Gómez,José Villalaín,José Manuel González Ros
Protein Lipid Interactions Book PDF

Author : C.Reyes Mateo,Javier Gómez,José Villalaín,José Manuel González Ros
Publisher : Springer Science & Business Media
Page : 260 pages
File Size : 51,9 Mb
Release : 2008-09-30
Category : Science
ISBN : 3540852824

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Protein-Lipid Interactions by C.Reyes Mateo,Javier Gómez,José Villalaín,José Manuel González Ros Pdf

Biological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein–lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane.

Protein-Lipid Interactions

Lukas K. Tamm
Protein Lipid Interactions Book PDF

Author : Lukas K. Tamm
Publisher : John Wiley & Sons
Page : 470 pages
File Size : 54,7 Mb
Release : 2006-05-12
Category : Science
ISBN : 9783527606993

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Protein-Lipid Interactions by Lukas K. Tamm Pdf

In 17 contributions by leading research groups, this first comprehensive handbook in the field covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle. It examines the relevant hermodynamic and structural issues from a basic science perspective, and goes on to discuss biochemical and cell biological processes. The book covers physical principles as well as mechanisms of membrane fusion and fission. Additionally, chapters on bilayer structure and protein-lipid interactions as well as on how proteins shape lipids and vice versa, membrane penetration by toxins, protein sorting, and allosteric regulation of signal transduction across membranes make this a valuable information source for researchers in academia and industry.

Free Energy Calculations

Christophe Chipot,Andrew Pohorille
Free Energy Calculations Book PDF

Author : Christophe Chipot,Andrew Pohorille
Publisher : Springer Science & Business Media
Page : 528 pages
File Size : 45,5 Mb
Release : 2007-01-08
Category : Language Arts & Disciplines
ISBN : 9783540384472

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Free Energy Calculations by Christophe Chipot,Andrew Pohorille Pdf

Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react. Examples of problems in which knowledge of the underlying free energy behaviour is required, include conformational equilibria and molecular association, partitioning between immiscible liquids, receptor-drug interaction, protein-protein and protein-DNA association, and protein stability. This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles. The book is aimed at a broad readership of graduate students and researchers having a background in chemistry, physics, engineering and physical biology.

Handbook of Lipid Membranes

Cyrus R. Safinya,Joachim Radler
Handbook of Lipid Membranes Book PDF

Author : Cyrus R. Safinya,Joachim Radler
Publisher : CRC Press
Page : 371 pages
File Size : 44,6 Mb
Release : 2021-09-14
Category : Medical
ISBN : 9781466555730

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Handbook of Lipid Membranes by Cyrus R. Safinya,Joachim Radler Pdf

This handbook provides a unique overview of lipid membrane fundamentals and applications. The fascinating world of lipids that harbor and govern so many biological functionalities are discussed within the context of membrane structures, interactions, and shape evolution. Beyond the fundamentals in lipid science, this handbook focuses on how scientists are building bioinspired biomimetic systems for applications in medicine, cosmetics, and nanotechnology. Key Features: Includes experimental and theoretical overviews on the role of lipids, with or without associated biomolecules, as structural components imparting distinct membrane shapes and intermembrane interactions Covers the mechanisms of lipid-membrane curvature, by peptide and protein binding, and the roles of signalling lipids and the cytoskeleton in plasma membrane shape evolution Covers advanced X-ray and force measurement techniques Discusses applications in biomedicine, cosmetics, and nanotechnology, including lipid vectors in nucleic acid, drug delivery in dermal applications, and lipid-based sensors and artificial biointerfaces Covers artificial membranes from block copolymers, synthetic copolypeptides, and recombinant proteins Includes an exciting section that explores the role of lipids in the origin of life in hydrothermal conditions This book is a highly informative companion for professionals in biophysics, biochemistry, physical chemistry, and material and pharmaceutical sciences and bioengineering.

Lipid Bilayers

J. Katsaras,T. Gutberlet
Lipid Bilayers Book PDF

Author : J. Katsaras,T. Gutberlet
Publisher : Springer Science & Business Media
Page : 304 pages
File Size : 50,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9783662044964

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Lipid Bilayers by J. Katsaras,T. Gutberlet Pdf

Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.

Lipid-Protein Interactions

Jorg H. Kleinschmidt
Lipid Protein Interactions Book PDF

Author : Jorg H. Kleinschmidt
Publisher : Humana Press
Page : 476 pages
File Size : 53,9 Mb
Release : 2016-05-01
Category : Science
ISBN : 1493962639

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Lipid-Protein Interactions by Jorg H. Kleinschmidt Pdf

This book provides a selection of protocols to examine protein-lipid interactions, membrane and membrane protein structure, how membrane proteins affect lipids and how they are in turn affected by the lipid bilayer and lipid properties.

Membrane Biophysics

Mohammad Ashrafuzzaman,Jack A. Tuszynski
Membrane Biophysics Book PDF

Author : Mohammad Ashrafuzzaman,Jack A. Tuszynski
Publisher : Springer Science & Business Media
Page : 190 pages
File Size : 41,9 Mb
Release : 2012-08-28
Category : Science
ISBN : 9783642161056

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Membrane Biophysics by Mohammad Ashrafuzzaman,Jack A. Tuszynski Pdf

Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doors for high-level pharmaceutical approaches towards fighting membrane- and cell-related diseases.

The Physical Chemistry of MEMBRANES

B. Silver
The Physical Chemistry of MEMBRANES Book PDF

Author : B. Silver
Publisher : Springer Science & Business Media
Page : 413 pages
File Size : 49,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401096287

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The Physical Chemistry of MEMBRANES by B. Silver Pdf

Ls book is an account of what physical chemistry h . . to say about the structural, electrical and transport properties of biological membranes and their simplest model-the lipid bilayer. The accent throughout is on basic ideas. In contrast to the essentially descriptive ap proach characteristic of texts on membrane biochemistry, our underlying themes are the role of force and entropy in maintaining membrane organization, in determining the electric fields and ionic environment of membranes, and in regulating the passage of molecules and ions across membranes. Although experimental findings will always be the touch stone against which theory will be tried, no attempt is made to present an exhaustive survey of experimental data. On the other hand, there is discussion of the nature and limitations of the results obtainable by the major laboratory techniques. The treatment is at the level of an advanced undergraduate course or an introductory survey suitable for post graduate students carrying out research in biochemistry, biophysics, or physiology. The mathematical demands on the reader are trivial. The few forbidding equations appearing in Chapter 7 are soon whittled away to simple practical expressions. Although the current-voltage characteristics of nerves are traditionally the province of biophysics rather than physical chemistry, certain aspects relevant to the electrical activity of nerves are nevertheless included in this text, namely, mem brane and diffusion potentials and conductivity fluctuations. Where rival theories exist, conflicting convictions have been presented, but not necessarily accorded equal approbation. The author has a viewpoint.

Physics of Biological Membranes

Patricia Bassereau,Pierre Sens
Physics of Biological Membranes Book PDF

Author : Patricia Bassereau,Pierre Sens
Publisher : Springer
Page : 623 pages
File Size : 44,5 Mb
Release : 2018-12-30
Category : Science
ISBN : 9783030006303

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Physics of Biological Membranes by Patricia Bassereau,Pierre Sens Pdf

This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.

Biophysical Chemistry

Robin Leatherbarrow,R H Templer
Biophysical Chemistry Book PDF

Author : Robin Leatherbarrow,R H Templer
Publisher : Royal Society of Chemistry
Page : 292 pages
File Size : 52,8 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847550255

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Biophysical Chemistry by Robin Leatherbarrow,R H Templer Pdf

In the post-genomic world, advances in the comprehension of cell behaviour will depend upon scientists deciphering the molecular basis of interactions between proteins and membranes. Bringing together contributions from chemists, biologists and physicists, Biophysical Chemistry: Membranes and Proteins demonstrates how multidisciplinary teams can gain insights into understanding complex biological systems. This book reflects both the scope and the interdisciplinary nature of the field, with topics including: modelling of biological systems; membrane structure and interactions; probing biomolecules; and channels and receptors. Full of stimulating articles and opinions, readers from academia and industry will welcome the wide range of coverage and the state-of-the-art science.

Structure and Dynamics of Membranes

R. Lipowsky,E. Sackmann
Structure and Dynamics of Membranes Book PDF

Author : R. Lipowsky,E. Sackmann
Publisher : Elsevier
Page : 537 pages
File Size : 40,6 Mb
Release : 1995-06-15
Category : Technology & Engineering
ISBN : 9780080541914

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Structure and Dynamics of Membranes by R. Lipowsky,E. Sackmann Pdf

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Advances in Planar Lipid Bilayers and Liposomes

Ales Iglic
Advances in Planar Lipid Bilayers and Liposomes Book PDF

Author : Ales Iglic
Publisher : Academic Press
Page : 240 pages
File Size : 46,7 Mb
Release : 2011-05-25
Category : Science
ISBN : 0123884055

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Advances in Planar Lipid Bilayers and Liposomes by Ales Iglic Pdf

Advances in Planar Lipid Bilayers and Liposomes volumes cover a broad range of topics, including main arrangements of the reconstituted system, namely planar lipid bilayers as well as spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field. Incorporates contributions from newcomers and established and experienced researchers Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives Serves as an indispensable source of information for new scientists

Cell Boundaries

Stephen H White,Gunnar von Heijne,Donald M Engelman
Cell Boundaries Book PDF

Author : Stephen H White,Gunnar von Heijne,Donald M Engelman
Publisher : Garland Science
Page : 565 pages
File Size : 50,7 Mb
Release : 2021-12-31
Category : Medical
ISBN : 9781000508536

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Cell Boundaries by Stephen H White,Gunnar von Heijne,Donald M Engelman Pdf

The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures—and misadventures—of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications

Protein-Lipid Interactions

Anthony Watts
Protein Lipid Interactions Book PDF

Author : Anthony Watts
Publisher : Elsevier
Page : 378 pages
File Size : 44,7 Mb
Release : 1993-10-08
Category : Science
ISBN : 0080860850

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Protein-Lipid Interactions by Anthony Watts Pdf

Protein-lipid interactions as a field of study is now a mature area, and this volume of New Comprehensive Biochemistry has been published with two objectives in mind. Firstly, to look to the future, and try to envisage how the subject may develop in the near to medium future. Secondly, to present contrasting or complementary views on the same system. For example, the acetylcholine receptor is discussed from a predominantly structural aspect by Barrantes, and from the kinetic standpoint by Rankin, et al. The volume not only gives an update on specific aspects of the field, but also shows the way in which the phenomenon of protein-lipid interactions is now seemingly infiltrating many areas of biomembrane research, from recombinant DNA studies, protein insertion and assembly and reconstitution considerations to structural studies of membrane proteins.