Membrane Structural Biology

Author : Mary Luckey
Publisher : Cambridge University Press
Page : 427 pages
File Size : 41,9 Mb
Release : 2014-02-24
Category : Science
ISBN : 9781107729339

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Membrane Structural Biology by Mary Luckey Pdf

This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.

Author : Mary Luckey
Publisher : Cambridge University Press
Page : 427 pages
File Size : 42,5 Mb
Release : 2014-02-24
Category : Computers
ISBN : 9781107030633

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Membrane Structural Biology by Mary Luckey Pdf

An updated edition on membrane biology, providing new high resolution structures of membrane proteins and insights into how they function.

Author : William Stillwell
Publisher : Elsevier
Page : 590 pages
File Size : 51,5 Mb
Release : 2016-06-30
Category : Science
ISBN : 9780444637901

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An Introduction to Biological Membranes by William Stillwell Pdf

Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure. A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. Every aspect of membrane structural studies involves parameters that are very small and fast. Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science. Significantly expanded coverage on function, composition, and structure Brings together complex aspects of membrane research in a universally understandable manner Features profiles of membrane pioneers detailing how contemporary studies originated Includes a timeline of important discoveries related to membrane science

Author : Camilo Perez,Timm Maier
Publisher : Humana
Page : 423 pages
File Size : 41,9 Mb
Release : 2021-03-14
Category : Science
ISBN : 1071603752

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Expression, Purification, and Structural Biology of Membrane Proteins by Camilo Perez,Timm Maier Pdf

This book collects up-to-date advanced protocols and advice from leading experts in the area of membrane protein biology that can be applied to structural and functional studies of any membrane protein system. The contents explore methods for cloning and expression of membrane proteins and membrane protein complexes in prokaryotic and eukaryotic systems, approaches for protein purification, nanobody applications, as well as biophysical characterization and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Expression, Purification, and Structure Biology of Membrane Proteins serves to guide and encourage young researchers and newcomers to the field to tackle bold new studies on membrane proteins. Chapter 11 is available open access under a CC-BY 4.0 license via link.springer.com.

Author : Subrata Pal
Publisher : Academic Press
Page : 518 pages
File Size : 47,5 Mb
Release : 2019-08-13
Category : Science
ISBN : 9780128148563

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Fundamentals of Molecular Structural Biology by Subrata Pal Pdf

Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease

Author : Philip L. Yeagle
Publisher : CRC Press
Page : 398 pages
File Size : 54,6 Mb
Release : 2011-07-18
Category : Medical
ISBN : 9781439809587

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The Structure of Biological Membranes by Philip L. Yeagle Pdf

Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 55,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Anders Liljas
Publisher : World Scientific
Page : 581 pages
File Size : 55,5 Mb
Release : 2009
Category : Science
ISBN : 9789812772077

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Textbook of Structural Biology by Anders Liljas Pdf

A textbook for undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine. It covers various aspects of proteins, nucleic acids and lipids, including the rise and fall of proteins, membranes and gradients, the structural biology of cells, and evolution - the comparative structural biology.

Author : Reinhard Grisshammer,Susan K Buchanan
Publisher : Royal Society of Chemistry
Page : 414 pages
File Size : 43,5 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847552563

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Structural Biology of Membrane Proteins by Reinhard Grisshammer,Susan K Buchanan Pdf

In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue. Structural Biology of Membrane Proteins is a new monograph covering a wide range of topics with contributions from leading experts in the field. The book is split into three sections: the first discusses topics such as expression, purification and crystallisation; the second covers characterisation techniques and the final section looks at new protein structures. The book will hence have wide appeal to researchers working in and around the field and provide an up-to-date reference source. Introductory sections to each topic are accompanied by more detailed discussions for the more experienced biochemist. Detailed descriptions of experimental methods are included to demonstrate practical approaches to membrane protein structure projects. The book also offers an up-to-date reference source in addition to descriptions of new and emerging developments, including state-of-the-art techniques for solving membrane protein structures. Structural Biology of Membrane Proteins encompasses both basic introductions and detailed descriptions of themes and should appeal to a wide range of biochemical scientists, both experienced and beginner.

Author : Camilo Perez,Timm Maier
Publisher : Humana
Page : 0 pages
File Size : 54,6 Mb
Release : 2020-02-29
Category : Science
ISBN : 1071603728

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Expression, Purification, and Structural Biology of Membrane Proteins by Camilo Perez,Timm Maier Pdf

This book collects up-to-date advanced protocols and advice from leading experts in the area of membrane protein biology that can be applied to structural and functional studies of any membrane protein system. The contents explore methods for cloning and expression of membrane proteins and membrane protein complexes in prokaryotic and eukaryotic systems, approaches for protein purification, nanobody applications, as well as biophysical characterization and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Expression, Purification, and Structure Biology of Membrane Proteins serves to guide and encourage young researchers and newcomers to the field to tackle bold new studies on membrane proteins. Chapter 11 is available open access under a CC-BY 4.0 license via link.springer.com.

Author : H.R. Petty
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 42,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781489911469

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Molecular Biology of Membranes by H.R. Petty Pdf

This text attempts to introduce the molecular biology of cell membranes to students and professionals of diverse backgrounds. Although several membrane biology books are available, they do not integrate recent knowledge gained using modern molecular tools with more traditional membrane topics. Molecular techniques, such as cDNA cloning and x-ray diffraction, have provided fresh insights into cell membrane structure and function. The great excitement today, which I attempt to convey in this book, is that molecular details are beginning to merge with physiological responses. In other words, we are beginning to understand precisely how membranes work. This textbook is appropriate for upper-level undergraduate or beginning graduate students. Readers should have previous or concurrent coursework in biochemistry; prior studies in elementary physiology would be helpful. I have found that the presentation of topics in this book is appropriate for students of biology, biochemistry, biophysics and physiology, chemistry, and medicine. This book will be useful in courses focusing on membranes and as a supplementary text in biochemistry courses. Professionals will also find this to be a useful resource book for their personal libraries.

Author : Kenneth H. Lundstrom
Publisher : CRC Press
Page : 401 pages
File Size : 53,6 Mb
Release : 2006-02-23
Category : Medical
ISBN : 9781420016086

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Structural Genomics on Membrane Proteins by Kenneth H. Lundstrom Pdf

While the genomic revolution has quickly led to the deposit of more than 30,000 structures in the protein data bank (PDB), less than one percent of those contributions represent membrane proteins despite the fact that membrane proteins constitute some 20 percent of all proteins. This discrepancy becomes significantly troublesome when it is coupled

Author : William Stillwell
Publisher : Newnes
Page : 378 pages
File Size : 52,8 Mb
Release : 2013-04-20
Category : Science
ISBN : 9780080931289

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An Introduction to Biological Membranes by William Stillwell Pdf

An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.

Author : Jean-Paul Renaud
Publisher : John Wiley & Sons
Page : 1367 pages
File Size : 52,5 Mb
Release : 2020-01-09
Category : Medical
ISBN : 9781118900505

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Structural Biology in Drug Discovery by Jean-Paul Renaud Pdf

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Author : Dennis Chapman
Publisher : Springer
Page : 423 pages
File Size : 55,8 Mb
Release : 1983-06-18
Category : Science
ISBN : 9781349060658

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Biomembrane Structure and Function by Dennis Chapman Pdf