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Author : Hailiang Tang,Ian Dunn
Publisher : Frontiers Media SA
Page : 331 pages
File Size : 44,5 Mb
Release : 2023-04-25
Category : Medical
ISBN : 9782832521397
Author : Hailiang Tang,Allen Ho
Publisher : Frontiers Media SA
Page : 409 pages
File Size : 55,5 Mb
Release : 2021-12-29
Category : Medical
ISBN : 9782889718702
Author : Jeremy Rees,Patrick Y Wen
Publisher : Elsevier Health Sciences
Page : 484 pages
File Size : 44,5 Mb
Release : 2010-05-12
Category : Medical
ISBN : 9781455703777
Neuro-Oncology—a new title in the Blue Books of Practical Neurology series—is a concise and clinically applicable guide to this dynamic subspecialty. Jeremy Rees, PhD, MRCP and Patrick Y. Wen, MD present the most current information on the treatment and management of primary CNS tumors, secondary brain tumors, and the neurological complications of other cancers and their therapies in a format and scope appealing to both the general neurologist and the subspecialist. Access comprehensive coverage of treatment for adult and pediatric conditions—including tumors of the spinal cord as well as the brain. Find coverage of recent advances easily thanks to the emphasis on the latest clinical and laboratory findings and their implications for clinical management and treatment. Apply the possibilities and outcomes of neuro-oncologic surgery within the context of neurologic practice. Address the neurologic complications of cancer and its treatment as well as of primary and secondary tumors. Tap into the global perspectives of experts from all around the world for a multi-disciplinary approach to practice.
Author : Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publisher : Academic Press
Page : 554 pages
File Size : 54,6 Mb
Release : 2021-04-09
Category : Medical
ISBN : 9780128217559
Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Author : Jennifer Moliterno,Antonio Omuro
Publisher : Springer Nature
Page : 245 pages
File Size : 44,8 Mb
Release : 2020-12-18
Category : Medical
ISBN : 9783030595586
This book provides a comprehensive overview of the multidisciplinary management of meningiomas, followed by evaluation and management considerations along a spectrum of benign to more malignant behavior. It outlines the management of presumed Grade 1 tumors and how to identify features of tumors radiographically and clinically that may support a benign course rather than aggressive and vice versa. Following a stepwise progression from simple to complex, chapters introduce and tackle more aggressive meningiomas and tumor recurrence (of all Grades), with paradigms for evaluation and treatment. Tumor biology and genomics are fundamental and largely focused in the book. More recent findings which have directed personalized medicine and clinical trials are also addressed. Meningiomas: Comprehensive Strategies for Management addresses all aspects of the evaluation and care of patients with all WHO grades of meningiomas. It is highly informative and provides clarity for a wide audience of neurosurgeons, reconstructive surgeons, oncologists, neurologists, radiation oncologists, pathologists, radiologists, residents and students who treat these patients and those who are training for a career in managing patients with these potentially challenging tumors.
Author : Erik R. Ranschaert,Sergey Morozov,Paul R. Algra
Publisher : Springer
Page : 373 pages
File Size : 55,8 Mb
Release : 2019-01-29
Category : Medical
ISBN : 9783319948782
This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.
Author : A. Pansini,F. Lo Re,P. Conti,E. Montali,G- De Luca
Publisher : Springer Science & Business Media
Page : 435 pages
File Size : 44,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9788847022607
Since Harvey Cushing's extensive study on brain meningiomas no similar study has been conducted on spinal cord meningiomas. The high scientific value of this book is based on the careful elaboration of data from patients affected by spinal meningiomas who have been examined and operated on over the last 33 years (1962-1995) at the Neurosurgical School of the University of Florence, Italy. The main focus of this study was on the anatomic and clinical relationship that enabled early diagnosis of spinal meningiomas. More over this book emphasizes the interaction between neurology and neuroradiology in the form of "dynamic neurology". Myeloradiculographic findings are described together with those using more recent techniques such as CT and MRI.
Author : Franco DeMonte,Michael W McDermott,Ossama Al-Mefty
Publisher : Thieme
Page : 942 pages
File Size : 45,9 Mb
Release : 2011-05-17
Category : Medical
ISBN : 9781604063943
Al-Mefty's Meningiomas, Second Edition is the definitive guide to meningioma diagnosis, treatment, and surgery, and reflects over a decade of major advances in the diagnosis and management of both intracranial and spinal meningiomas since the first edition was published.The text begins with important information on anatomy, pathology, and epidemiology, followed by clinical and preoperative considerations. The expert authors then provide detailed descriptions of state-of-the-art surgical approaches listed by anatomical site and special operative considerations for intracranial meningiomas. The book closes with incisive discussion of breakthroughs in radiosurgery, radiotherapy and chemotherapy.Features[li]New to this edition: information on molecular biology, natural history and growth rates, the rise of radiosurgery as a viable treatment option, and much more[/li][li]Over 500 high-quality radiographic images and full-color illustrations demonstrate anatomy and surgery[/li][li]In-depth coverage of intraoperative MRI and endoscopic resection[/li][li]Key topics often missing from other meningiomas texts including caseload management, and postoperative quality of life issues[/li]This landmark reference will enhance the precision and surgical skills of every clinician or resident in neurosurgery or neurology.
Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 46,5 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author : Valeria Barresi
Publisher : Unknown
Page : 284 pages
File Size : 53,9 Mb
Release : 2022
Category : Electronic
ISBN : 3036529233
Colorectal cancer is one of the most common malignancies worldwide, and the pathogenesis of this neoplasm is probably one of the most studied. The knowledge obtained over time has led to the development of screening and early diagnosis systems, allowing a significant reduction in the incidence of this neoplasm. However, what is currently known probably represents only the tip of the iceberg of the biology of this tumor. It was recently shown that the gut microbiota may contribute to colorectal cancerogenesis. In addition, several novel targeted therapies are now applied to patients with colorectal carcinoma. Nonetheless, several questions are still unanswered. Could the modulation of the gut microbiota modify the risk of tumor progression or the efficacy of therapies? Are there any predictive biomarkers of the risk of tumor progression or the efficacy of target therapies? Is metastatic colorectal cancer one or more diseases? This book collects a series of scientific articles reflecting part of the state of the art regarding colorectal cancer, seeking to answer these questions.
Author : Asfar Azmi,Ramzi M. Mohammad
Publisher : Academic Press
Page : 470 pages
File Size : 45,9 Mb
Release : 2019-04-16
Category : Business & Economics
ISBN : 9780128147054
Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field. Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid systems, humanized and other models in modern biology paradigms that are enhancing research in the field of drug discover Covers the use of these models in personalized medicine, immunotherapy, toxicology, pre-IND assessments and related drug development arenas Presents protocols, procedures, and a comprehensive glossary to help new readers understand technical terms and specialized nomenclature
Author : Michael W. McDermott
Publisher : Elsevier
Page : 0 pages
File Size : 45,9 Mb
Release : 2020-07-30
Category : Medical
ISBN : 012804280X
Meningiomas, Volume 169, Part One, serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type. In this volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons - have provided up-to-date synopses of each topic as it relates to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments.
Author : Richard Francis Mould
Publisher : Cyberknife Society
Page : 428 pages
File Size : 40,5 Mb
Release : 2005
Category : Cancer
ISBN : 0975312413
Covers a wide range of topics on robotic radiosurgery. General topics on robotic radiosurgery include: 9 chapters on history, physics, radiobiology and technology and 24 chapters on CNS, non-CNS and future applications in robotic radiosurgery. Includes 157 figures and 93 tables,
Author : Karel Pacak,Graeme Eisenhofer,Jacques Lenders
Publisher : John Wiley & Sons
Page : 184 pages
File Size : 53,9 Mb
Release : 2008-04-15
Category : Medical
ISBN : 9780470766385
Pheochromocytomas are rare but treacherous catecholamine-producing tumors, which if missed or not properly treated, will almost invariably prove fatal. Prompt diagnosis is, therefore, essential for effective treatment, usually by surgical resection. The manifestations are diverse and the tumor can mimic a variety of conditions, often resulting in either erroneous diagnoses or a delayed diagnosis. Reflecting the recent leaps in understanding this condition, Pheochromocytoma: Diagnosis, Localization, and Treatment provides a comprehensive update on the improvements in the diagnosis, localization, management and treatment of pheochromocytomas – providing you with the latest cutting edge science alongside best clinical practice. Written by the leading names in the field, the text details the significant developments in understanding the genetics and biology of the tumors, coupled with technological advances in the fields of analytical chemistry, genomics, molecular biology and nuclear medicine. The most comprehensive book on pheochromocytoma Provides cutting edge science and clinical guidance Written by the leading names in the field Authors present their recently developed novel biochemical test for the diagnosis of Pheochromocytoma
Author : William T. Couldwell
Publisher : Springer
Page : 228 pages
File Size : 52,9 Mb
Release : 2017-11-10
Category : Medical
ISBN : 9783319670386
This text provides a comprehensive and contemporary overview of surgical approaches to lesions of the posterior fossa. It will serve as a resource for neurosurgeons and otologists who treat patients with tumors and vascular diseases of the posterior fossa. It provides a concise review of surgical strategies that address the most important pathologies affecting the posterior fossa. It is richly illustrated with photographs and illustrations of the surgical strategies covered. All chapters are written by experts with world-wide recognition for their contributions in their respective subspecialty. Skull Base Surgery of the Posterior Fossa will be of great utility to Neurosurgeons, Otolaryngologists, and Radiation Therapists with an interest in diseases that affect the posterior fossa, as well as Senior Residents in Neurosurgery and Otolaryngology, and Fellows of Skull Base Surgery and Otology.