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Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts,Lucy Croucher
Author : Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts,Lucy Croucher Publisher : Royal Society of Chemistry Page : 872 pages File Size : 49,6 Mb Release : 2007-10-31 Category : Technology & Engineering ISBN : 9781847551382
Metabolic Pathways of Agrochemicals by Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts,Lucy Croucher Pdf
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts
Author : Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts Publisher : Royal Society of Chemistry Page : 1502 pages File Size : 46,7 Mb Release : 2007-10-31 Category : Technology & Engineering ISBN : 9781847551375
Metabolic Pathways of Agrochemicals by Terry R Roberts,David H Hutson,Philip W Lee,Peter H Nicholls,Jack R Plimmer,Marie C Roberts Pdf
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
Metabolic Pathways of Agrochemicals: Insecticides and fungicides by Terence Robert Roberts,David Herd Hutson Pdf
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
Metabolic Pathways of Agrochemicals by Terry R. Roberts Pdf
Annotation Based on literature (and some unpublished work provided by agrochemical companies), this sizable single volume provides a summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants, and animals. Entries are organized by class of chemical and cover most commercially available chemicals in use today--including modulators of insect growth and behavior, rodenticides and nematicides. Introductions to each section provide an overview of the metabolism of each major class. The editors include independent consultants and researchers from JSC International Ltd., Shell Research Ltd., E.I. Du Pont de Nemours & Co., and IACR- Rothamsted. Annotation c. Book News, Inc., Portland, OR (booknews.com).
People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the "metabolic pathways" or "maps" for the chemical compounds that they are using or proposing. Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds. Covers literature relating to degradation and metabolic profiles of molecules Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology
Metabolic Maps of Pesticides by Hiroyasu Aizawa Pdf
Metabolic Maps of Pesticides provides a summary of investigations and drawings of the metabolic patterns on pesticides that were collected with the aid of Chemical Abstracts Service (CAS) for the years 1970-1979. Some maps were taken from the original reports, some were slightly modified for clarity, and some were tentatively drawn from descriptions in the original articles. The pesticides are classified based on their chemical structures as functional groups or based on common chemical nomenclature. The chemical classifications highlight the properties of the mother pesticides and the impact of their degenerative metabolites on the environment. Metabolic maps are provided for the following: acid amides, amidines and guanidines, anilines and nitrobenzenes, biphenyl ethers, DDT and its analogs, dithio- and thiolcarbamates, five- and six-membered heterocyclic compounds, imides, organochlorine compounds, oxime carbamates, phenoxyacetic acids, pheny ring fused five-membered heterocyclic compounds, phenyl(aryl) carbamates, phenylureas and related compounds, phosphonothiolates and phosphonothioates, phosphonates, phosphorothioamides, phosphates, phosphorothiolates, pyrethroids, pyridines, triazines, and substituted benzenes and miscellaneous compounds.
Progress in Pesticide Biochemistry and Toxicology, The Mammalian Metabolism of Agrochemicals by D. H. Hutson,G. D. Paulson Pdf
Progress in Pesticide Biochemistry and Toxicology Volume 8 Series Editors D. H. Hutson, Shell Research Ltd, Sittingbourne, UK and T. R. Roberts, Hazleton UK, Harrogate, UK The Mammalian Metabolism of Agrochemicals Edited by D. H. Hutson, Shell Research Ltd, Sittingbourne, UK and G. D. Paulson, US Department of Agriculture, Fargo, USA The Mammalian Metabolism of Agrochemicals is the eighth volume in the Progress in Pesticide Biochemistry and Toxicology series, and collates the various aspects of pesticide metabolism in mammals. The main aims of toxicity and metabolism studies are the assessment of the toxicity of a test compound to man and other mammals, and to evaluate the acceptability of residues which might be found in livestock products for human consumption. The Mammalian Metabolism of Agrochemicals covers the biochemical processes involved in the metabolism of xenobiotics, design of studies to meet current regulatory requirements, the metabolism of herbicides, fungicides and insecticides, factors effecting pesticide metabolism in man and other mammals and examples of natural toxins. This volume provides a comprehensive and extensively referenced source of information, written by leading researchers in this field.
Metabolism of Agrochemicals in Plants by Terence Robert Roberts Pdf
The importance of understanding the metabolism of agrochemicals in plants has never been greater. In a world where food safety and environmental concerns are increasing, knowledge of the metabolic processes within plants and the terminal residues of agrochemicals in food crops is invaluable. Written by experts in the agrochemical industry and academia, Metabolism of Agrochemicals in Plants is the first text to give systematic coverage of this important topic. This text brings together the current status of the subject with chapters on regulatory considerations, comparative metabolism of plants and animals, and the different phases of metabolism. Including new and novel research in primary metabolism, herbicide metabolism and bound residues, this work is unique and thoroughly up to date. This is an essential text for chemists and biochemists working in the agrochemical and pharmaceutical industries and academia as well as analytical chemists, regulatory chemists and environmental scientists. Metabolism of Agrochemicals in Plants is a volume in the Wiley Series in Agrochemicals and Plant Protection. This series brings together current scientific and regulatory knowledge and perspectives on all aspects of the use of chemicals and biotechnology in agriculture.
Handbook of Metabolic Pathways of Xenobiotics by Philip Lee,Hiroyasu Aizawa,Lawrence Gan,Chandra Prakash,Dafang Zhong Pdf
If you’re working on or studying the effects of drug metabolisms, then this reference is for you! Handbook of Metabolic Pathways of Xenobiotics is an essential new reference which presents the metabolic fate of xenobiotics in animals and plants, and shows the metabolic pathways in the environment. Presenting a comprehensive guide to understanding the metabolisms of xenobiotics, the Handbook of Metabolic Pathways of Xenobiotics spans five volumes: Volumes 1-2 are Review Articles and Volumes 3-5 are Compound Articles. Review Articles present detailed reviews on the techniques and methods used to establish in vitro and in vivo metabolic pathways. Compound Articles are carefully selected lists of key chemicals representing agrochemicals, pharmaceuticals, animal health products and industrial chemicals. An essential addition to every library, this introduction, guide and catalogue presents: Current topics in the metabolism of xenobiotics Topics of both scientific and regulatory importance are covered, including in vitro high throughput metabolism screens, computer-aided metabolism predictions, and advances in bioanalytical techniques. Techniques and methods used in metabolic pathways 29 chapters provide an introduction to the understanding of drug metabolism and detail how to establish in vitro and in vivo metabolic pathways. Biotransformation pathways Presented as a catalogue of short articles covering major pharmaceuticals, agrochemicals, animal health products and industrial chemicals. Each article summarizes the chemical properties and uses, and presents a detailed review of the chemical and metabolic pathways in soil, plants and animals. Over 450 examples of xenobiotics and their fate in animals and plants Each compound includes systematic information about the metabolic pathway of drugs for human and veterinary medicine, agrochemicals and major industrial chemicals. Chemical and biological fate data The Handbook summarises data from scientific literature, patent literature, industrial resources and regulatory agencies, such as the EPA, FDA, EU, WHO and FAO, in a single reference for the first time. An essential reference for everyone working and studying pharmacokinetics and drug metabolism Coverage of the chemical and biological reactivity of molecules and primary sub-structures makes this an ideal reference for students and research scientists. The broad and diverse coverage of chemical and biological fate under different exposure and biological compartments make this a useful resource for regulatory and developmental scientists. Experience the scope of content offered in the Handbook of Metabolic Pathways of Xenobiotics for yourself, download these articles today: Review Article: Fundamentals of organic chemistry as applicable to the biotransformation of foreign compounds Review Article: Metabolic stability screen in drug discovery Review Article: Unusual metabolic reactions and pathways Compound Article: Ganoderic acid D Compound Article: Milnacipran Compound Article: Tenofovir Online Edition Coming Soon! Featuring the same great content as the five volume print set, the Handbook of Metabolic Pathways for Xenobiotics will be available on Wiley Online Library in summer 2014. The online reference will benefit from the enhanced functionality powered by The Smart Article – learn more about The Smart Article at wileyonlinelibrary.com/thesmartarticle. Free trials will be available when the Online Edition goes live, bookmark this page or sign-up for regular product alerts at www.wiley.com/email to stay informed.
Plant Secondary Metabolism Engineering by Arthur Germano Fett-Neto Pdf
Plants have evolved an amazing array of metabolic pathways leading to molecules capable of responding promptly and effectively to stress situations imposed by biotic and abiotic factors, some of which supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, food and chemical additives, biofuels, and biomass. In Plant Secondary Metabolism Engineering: Methods and Applications, expert researchers provide detailed practical information on some of the most important methods employed in the engineering of plant secondary metabolism pathways and in the acquisition of essential knowledge in performing this activity, including the significant advances and emerging strategies. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Plant Secondary Metabolism Engineering: Methods and Applications will aid scientists engaged in the challenging task of modifying some of the most intricate products of plant evolution and support their efforts directed toward the vital goal of sustainable natural chemicals.
Pesticide Biotransformation and Disposition by Ernest Hodgson Pdf
Biotransformation of Pesticides is an updated, "one-stop" resource for academic, industry and regulatory scientists involved in research and regulatory activities related to pesticide biotransformation and human health. This book provides an in depth look at how pesticides are biotransformed, which is essential to understanding exposure, dose, toxicity and health risks. This essential reference contains the biotransformation of pesticides from uptake to excretion, including toxicokinetics and emphasizes metabolism in non-target species, including experimental animals and humans. Includes four new chapters and expanded material on pesticide biotransformation and disposition, an active area of pesticide toxicology that is becoming increasingly important for human health risk assessment Offers a practical and portable guide covering the most up-to-date research results on metabolic transformations of pesticides Provides scientists and regulatory researchers with the information they need to conduct accurate risk assessments and make informed decisions on which exposures to study further in human populations
Plant Toxicology by Bertold Hock,Erich F. Elstner Pdf
In order to keep track of all the compounds and pathogens affecting plant metabolism and development, you would need to spend all your waking hours combing periodicals and the Internet in dozens of languages, as new toxins via pollutants and migratory or mutant pathogens are being discovered every day. Plant Toxicology, Fourth Edition start
Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats Publisher : National Academies Press Page : 570 pages File Size : 42,6 Mb Release : 2011-12-30 Category : Science ISBN : 9780309219396
The Science and Applications of Synthetic and Systems Biology by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
