Metabolism In The Nervous System

Author : Abel Lajtha
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 50,8 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781461571605

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Metabolic Reactions in the Nervous System by Abel Lajtha Pdf

When the projected volumes of the Handbook are completed, most of our current knowledge of the biochemistry of nervous systems will have been touched upon. A number of the chapters will have dealt with the correlations of the biochemical findings with morphological and physio logical parameters as well. Considering the abysmal lack of such attempts, even in the recent past, this is a sign of great progress. If the reader's eventual goal is to derive the "laws" that relate various aspects of animal and human behavior to underlying physiological and biochemical function, these admirable volumes will help him to establish a firm biochemical base from which to operate. It is certain that the future approaches to the various problems of the information-processing functions of the nervous system will require an integrated understanding of the essence of all of the scientific disciplines which are grouped under the general name of neuro biology. The rich feast of information offered up in this Handbook will enable those in the non-chemical disciplines to pick and choose those areas of chemical information pertinent to their immediate interests. Similar types of compendia by physiologists, anatomists, cyberneticists, and psychologists have been helpful to chemists and continue to be so.

Author : Derek Richter
Publisher : Elsevier
Page : 664 pages
File Size : 41,5 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483184357

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Metabolism of the Nervous System by Derek Richter Pdf

Metabolism of the Nervous System contains the proceedings of the 2nd International Neurochemical Symposium, held at Aarhus, Denmark, in July 1956. The book discusses the molecular structure and morphology of the adult nervous tissue; the chemical composition and cytochemical localization of adult nervous tissue; and the permeability and blood-brain barrier. The text also describes topics on electrolytes and nervous conduction; the metabolism of isolated nerve and ganglion; and the metabolism of the brain in vivo. The metabolism of brain tissue preparations in vitro; energy metabolism and coenzymes in relation to the nervous system; and lipid and fatty acid metabolism are also considered. The book further tackles nucleic acid metabolism; protein and amino acid metabolism; and cholinergic and non-cholinergic transmission. The text also discusses other pharmacologically active compounds related to the adult nervous tissue.

Author : Abel Lajtha
Publisher : Springer Science & Business Media
Page : 707 pages
File Size : 47,5 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9781468443677

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Metabolism in the Nervous System by Abel Lajtha Pdf

This volume is concerned with metabolic reactions occurring in the nervous system. Some time ago, it was thought that since most of the intermediary metabolism that can be observed in the brain is not specific to this organ, there is little justification in studying neural metabolism as such. Later it was realized that for an understanding of neural functions, the understanding of metabolism in the brain and its alterations is essential. All aspects of the metabolism of a substrate in brain, or all metabolic reactions of the nervous system, could not be included in this volume; some will be dealt with in other volumes (such as the ones covering metabolic turn over, alterations of metabolism, or pathology). Review of the aspects covered here clearly shows that the study of metabolic reactions in the nervous system is a very active field, producing important results. As in so many areas of research, as we learn more, new aspects become known, new questions emerge, and we see that in solving some problems we open areas with many additional problems to solve. But the accomplishments to date are impressive and indicate further important advances in the future. Brain metabolism is more active, more plastic, and more comprehensive than previously estimated. It is an essential part of brain function, and with its alteration, brain function will be altered. This shows the importance of more knowledge in this area. It is hoped that this volume will be of assistance in such further studies.

Author : Abel Lajtha
Publisher : Unknown
Page : 728 pages
File Size : 54,7 Mb
Release : 2014-01-15
Category : Electronic
ISBN : 1468443682

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Metabolism in the Nervous System by Abel Lajtha Pdf

Author : E. Genazzani,H. Herken
Publisher : Springer Science & Business Media
Page : 410 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642657146

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Central Nervous System by E. Genazzani,H. Herken Pdf

This book is based on the Symposium "Metabolic Regulation and Functional Activity in the Central Nervous System" which was held on September 16 and 17, 1972, at Saint Vincent (Aosta)/Italy, and was sponsored by the Accademia di Medicina di Torino with the scientific cooperation of the Istituto di Farmacologia, Universita di Torino, and the Pharmakologisches Institut der Freien Universitat Berlin. Its purpose was to give a greater number of scientists from different countries an opportunity to report their latest results under a heading concerning general relationships between metabolism and function. We quite deliberately refrained from pursuing the partly heterogenous subjects into details. Thus, the organizers hoped to be able to interest a greater circle of readers for the manifold subjects from various fields dealing with the investigation of metabolic processes in the central nervous system. The discussion remarks to the lectures could not be considered for printing. The Accademia di Medicina di Torino and all others concerned do not only thank Dr. R. Di Carlo and other members of the Istituto di Farmacologia, Universita di Torino, for the excellent work they performed in preparing this Symposium, but also the Amministrazione Regionale della Valle di Aosta and SIT A V di Saint-Vincent for their generous support and their kind hospitality which made the stay at Saint-Vincent most agreeable for all participants.

Author : D. A. Rappoport,R. R. Fritz,S. Yamagami,Robert L. Herrmann,A. V. Palladin,N. M. Poljakova,Isaac Schenkein,Louis Sokoloff,A. Lajtha,N. Marks,J. R. Smythies,William A. Brodsky,Adil E. Shamoo,Irving L. Schwartz,H. R. Wyssbrod,W. N. Scott,W. A. Brodsky,I. L. Schwartz
Publisher : Springer Science & Business Media
Page : 412 pages
File Size : 51,9 Mb
Release : 2013-11-21
Category : Medical
ISBN : 9781461571698

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Metabolic Turnover in the Nervous System by D. A. Rappoport,R. R. Fritz,S. Yamagami,Robert L. Herrmann,A. V. Palladin,N. M. Poljakova,Isaac Schenkein,Louis Sokoloff,A. Lajtha,N. Marks,J. R. Smythies,William A. Brodsky,Adil E. Shamoo,Irving L. Schwartz,H. R. Wyssbrod,W. N. Scott,W. A. Brodsky,I. L. Schwartz Pdf

Volume V deals with the problems of turnover in the nervous system. "Turnover" is defined in different ways, and the term is used in different contexts. It is used rather broadly in the present volume, and intentionally so. The turnover of macromolecules is only one aspect; here "turnover" in dicates the simultaneous and coordinated formation and breakdown of macromolecular species. The complexities of cerebral protein turnover are shown in aseparate chapter dealing with the synthesis ofproteins, in another on breakdown, and in still another on the relationship ofthese two (showing how the two halves of turnover are controlled). The fact that most likely the two halves of protein turnover, synthesis and breakdown, are separated spatially and the mechanisms involved are different further emphasizes the complexity of macromolecular turnover. "Turnover" is used in a different context when the turnover of a cycle is discussed; but he re again a number of complex metabolic reactions have to be interrelated and controlled; some such cycles are discussed briefly in this volume, additional cycles have been discussed with metabolism, and some cycles still await elucidation or discovery.

Author : Abel Lajtha
Publisher : Springer Science & Business Media
Page : 724 pages
File Size : 43,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468481099

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Protein Metabolism of the Nervous System by Abel Lajtha Pdf

Few can deny the paramount importance of the neurosciences, undoubtedly one of the most challenging fields in contemporary science. Recent years have witnessed the awakening of interest in brain research by many dis tinguished investigators from other branches of science, which has made possible the multidisciplinary approach needed for the complex problems of this field. The present book, which deals with one aspect of this research, is the result of the symposium held under the auspices of the New York State Research Institute for Neurochemistry and Drug Addiction in April 1968. It has become clear that brain proteins are involved in all aspects of mental function and dysfunction, and the present volume documents the latest advances in our knowledge (advances made to a large extent by con tributors to this volume). The chapters not only convey some of the enthu siasm and wonderful, cooperative spirit of the many excellent scientists ex ploring the brain, and their wealth of ideas; they also illustrate the many approaches from which cerebral proteins can be studied in a meaningful manner. In some areas even preliminary evidence is worth discussing: e.g., it is an exciting achievement that we can begin to apply the disciplines of bio chemistry to phenomena of learned behavior and information handling.

Author : Stanislav Tuček
Publisher : John Wiley & Sons
Page : 430 pages
File Size : 50,5 Mb
Release : 1987
Category : Central Nervous System
ISBN : UOM:39015012573567

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Metabolism and Development of the Nervous System by Stanislav Tuček Pdf

Proceedings of the Sixth General Meeting of the European

Author : Gary A. Rosenberg
Publisher : OUP USA
Page : 241 pages
File Size : 55,9 Mb
Release : 2012-04-30
Category : Medical
ISBN : 9780195394276

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Molecular Physiology and Metabolism of the Nervous System by Gary A. Rosenberg Pdf

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists. Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure. Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.

Author : Qi Wu,Ruimao Zheng
Publisher : Springer
Page : 233 pages
File Size : 40,5 Mb
Release : 2018-11-02
Category : Medical
ISBN : 9789811312861

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Neural Regulation of Metabolism by Qi Wu,Ruimao Zheng Pdf

This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.

Author : Abel Lajtha
Publisher : Springer Science & Business Media
Page : 512 pages
File Size : 44,9 Mb
Release : 2013-11-09
Category : Science
ISBN : 9781489945556

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Handbook of Neurochemistry by Abel Lajtha Pdf

Author : In-Young Choi,Rolf Gruetter
Publisher : Springer Science & Business Media
Page : 1168 pages
File Size : 47,7 Mb
Release : 2012-03-14
Category : Medical
ISBN : 9781461417873

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Neural Metabolism In Vivo by In-Young Choi,Rolf Gruetter Pdf

From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter

Author : M. Z. M. Ibrahim
Publisher : Unknown
Page : 92 pages
File Size : 46,5 Mb
Release : 2014-09-01
Category : Electronic
ISBN : 3642868762

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Glycogen and Its Related Enzymes of Metabolism in the Central Nervous System by M. Z. M. Ibrahim Pdf

Author : Abel Lajtha
Publisher : Springer
Page : 624 pages
File Size : 44,6 Mb
Release : 1995-12-31
Category : Medical
ISBN : 0306377039

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Metabolic Reactions in the Nervous System by Abel Lajtha Pdf

When the projected volumes of the Handbook are completed, most of our current knowledge of the biochemistry of nervous systems will have been touched upon. A number of the chapters will have dealt with the correlations of the biochemical findings with morphological and physio logical parameters as well. Considering the abysmal lack of such attempts, even in the recent past, this is a sign of great progress. If the reader's eventual goal is to derive the "laws" that relate various aspects of animal and human behavior to underlying physiological and biochemical function, these admirable volumes will help him to establish a firm biochemical base from which to operate. It is certain that the future approaches to the various problems of the information-processing functions of the nervous system will require an integrated understanding of the essence of all of the scientific disciplines which are grouped under the general name of neuro biology. The rich feast of information offered up in this Handbook will enable those in the non-chemical disciplines to pick and choose those areas of chemical information pertinent to their immediate interests. Similar types of compendia by physiologists, anatomists, cyberneticists, and psychologists have been helpful to chemists and continue to be so.

Author : Susan Masino,Detlev Boison
Publisher : Springer Science & Business Media
Page : 680 pages
File Size : 52,5 Mb
Release : 2012-08-30
Category : Medical
ISBN : 9781461439035

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Adenosine by Susan Masino,Detlev Boison Pdf

Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve behavior and cognition. Adenosine: A Key Link Between Metabolism and Central Nervous System Activity focusses on diverse aspects of adenosine, an evolutionarily conserved homeostatic bioenergetic regulator in the central nervous system. Because of its interrelationship with ATP (adenosine triphosphate), adenosine is integral to cell metabolism. At the same time, adenosine influences neuronal activity directly via receptors, and is involved in biochemical processes related to gene expression. Thus, adenosine is uniquely placed as a reciprocal and rapid link between changes in metabolism and changes in neuronal activity, and, on a longer time scale, to changes in gene expression and long term changes in cell function. Leaders in the field feature basic research on adenosine at the cellular level in the central nervous system, and relate these findings to its recognized potential in diverse acute and chronic disorders. This comprehensive overview of adenosine also highlights emerging adenosine-based treatments and associated opportunities for central nervous system disorders.