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Author : Roland C. Aloia,Cyril C. Curtain,Larry M. Gordon
Publisher : Unknown
Page : 352 pages
File Size : 45,6 Mb
Release : 1988
Category : Cell Membrane
ISBN : UOM:39015013203537
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Roland C. Aloia,Cyril C. Curtain,Larry M. Gordon
Publisher : Wiley-Liss
Page : 380 pages
File Size : 43,5 Mb
Release : 1988-08-16
Category : Science
ISBN : 047161744X
Author : Morris Kates
Publisher : Springer Science & Business Media
Page : 698 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468446678
The aim of this book is to bring together in one volume the current research and thought on the concept of membrane fluidity as a biological phenomenon. The invited articles are intended to review recent develop ments in the areas of membrane research covered and to summarize the current concepts and theories in those areas. The authors have been given ample opportunity to present their thoughts and speculation on membrane fluidity and related phenomena in a more expanded form than is usually possible in reviews of this type. It is hoped that this approach will have a stimulating effect on research and theoretical development in the biomem brane field. The chapters in this book are arranged in three sections, the first of which covers physical studies of membrane fluidity and related phenomena on the molecular level. Included are chapters on intermolecular hydrogen bonding between membrane lipids, thermal analysis of membranes, appli cation of fluorescence and NMR spectrometry to the study of membrane fluidity, and the effect of drugs and other compounds on membrane stability and fluidity. The second section deals with the regulation of membrane fluidity in microorganisms, plants, and higher organisms by factors such as tem perature, fatty acid chain length, lipid desaturation, and polar head group structure.
Author : Morris Kates,Arnisa Kuksis
Publisher : Unknown
Page : 464 pages
File Size : 41,9 Mb
Release : 1980-04-30
Category : Electronic
ISBN : 146126121X
Author : William Stillwell
Publisher : Newnes
Page : 378 pages
File Size : 51,7 Mb
Release : 2013-04-20
Category : Science
ISBN : 9780080931289
An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.
Author : Philip L. Yeagle
Publisher : CRC Press
Page : 398 pages
File Size : 49,8 Mb
Release : 2011-07-18
Category : Medical
ISBN : 9781439809587
Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition pro
Author : Edward D. Korn
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468429107
Although not the only volume in this series in which lipids are discussed, the present volume is devoted entirely to methods for the study of membrane lipids. Even now, when membrane proteins are properly receiving so much attention, this emphasis on membrane lipids is appropriate. Essentially all of the phospholipids and sterols of cells are in membranes. Moreover, although membrane proteins are certainly of utmost importance, the more we learn about the functional properties of membrane proteins, the more we appreciate the unique features of phospholipids, without which biological membranes would be impossible. The hydrophobic-hydrophilic duality of phospholipids allows, indeed requires, their association, in an aqueous environment, into an essentially two-dimensional membrane-only molec ularly thick in one dimension but relatively infinite in the other two; a structure composed of small molecules, not covalently linked, and therefore, infinitely mobile and variable, but yet a structure with great stability and one largely impermeable to most biomolecules. These membrane-forming properties are shared by many amphipathic polar lipids-phospholipids, glycolipids, and sphingolipids-that differ significantly from each other in the nature of their polar head groups and their fatty acids. These variations in structure allow a range of specific interactions among membrane lipids and between lipids and proteins and also provide for membranes of variable, but controlled, fluidity. In this way, phospholipids provide an appropriate milieu for functional membrane proteins and also significantly modulate their catalytic activities.
Author : Roland C. Aloia,Joan M. Boggs
Publisher : Academic Press
Page : 317 pages
File Size : 41,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483265537
Membrane Fluidity in Biology, Volume 4: Cellular Aspects provides a unique interpretation of membrane and cellular activity, as well as cellular aspects of membrane fluidity. This book discusses the influence of membrane fluidity on enzyme activity, function of the sarcoplasmic reticulum in skeletal muscle, role of cholesterol in membrane function, phospholipid methylation, glycosyltransferases, and membrane fusion. The realm of normal cellular function and mechanisms involved in the modulation of cellular function by membrane lipids are also elaborated in this publication. This volume is intended for cell and molecular biologists and clinical-medical scientists, but is also beneficial to individuals researching on the effects of membrane lipids and fluidity in cellular function.
Author : Meir Shinitzky
Publisher : Springer
Page : 152 pages
File Size : 54,9 Mb
Release : 1984
Category : Business & Economics
ISBN : UOM:39015007524146
Author : Edward D. Korn
Publisher : Springer
Page : 368 pages
File Size : 47,6 Mb
Release : 1977-01-01
Category : Science
ISBN : 0306368080
Although not the only volume in this series in which lipids are discussed, the present volume is devoted entirely to methods for the study of membrane lipids. Even now, when membrane proteins are properly receiving so much attention, this emphasis on membrane lipids is appropriate. Essentially all of the phospholipids and sterols of cells are in membranes. Moreover, although membrane proteins are certainly of utmost importance, the more we learn about the functional properties of membrane proteins, the more we appreciate the unique features of phospholipids, without which biological membranes would be impossible. The hydrophobic-hydrophilic duality of phospholipids allows, indeed requires, their association, in an aqueous environment, into an essentially two-dimensional membrane-only molec ularly thick in one dimension but relatively infinite in the other two; a structure composed of small molecules, not covalently linked, and therefore, infinitely mobile and variable, but yet a structure with great stability and one largely impermeable to most biomolecules. These membrane-forming properties are shared by many amphipathic polar lipids-phospholipids, glycolipids, and sphingolipids-that differ significantly from each other in the nature of their polar head groups and their fatty acids. These variations in structure allow a range of specific interactions among membrane lipids and between lipids and proteins and also provide for membranes of variable, but controlled, fluidity. In this way, phospholipids provide an appropriate milieu for functional membrane proteins and also significantly modulate their catalytic activities.
Author : E. Anibal Disalvo
Publisher : Springer
Page : 284 pages
File Size : 50,7 Mb
Release : 2015-10-05
Category : Science
ISBN : 9783319190600
This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system. The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics. Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems. These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry, biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.
Author : Thomas E. Andreoli,Darrell D. Fanestil,Joseph F. Hoffman,Stanley G. Schultz
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 50,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461319436
Membrane Physiology (Second Edition) is a soft-cover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the first three sections: The Nature of Biological Membranes, Methods for Studying Membranes, and General Problems in Membrane Biology. We hope that this smaller volume will be helpful to individuals interested in general physiology and the methods for studying general physiology. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ vii Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition. Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.
Author : Yves Mely,Guy Duportail
Publisher : Springer Science & Business Media
Page : 484 pages
File Size : 50,8 Mb
Release : 2012-10-10
Category : Science
ISBN : 9783642331275
Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.
Author : E. Grell
Publisher : Springer Science & Business Media
Page : 509 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642815379
The last 10 years have seen an enormous growth in our understanding of the molecular organisation of biological membranes. Experimental methods have been devised to meas ure the translational and rotational mobility of lipids and proteins, thereby furnishing a quantitative basis for the concept of membrane fluidity. Likewise, the asymmetry of bi layer membranes as evidenced by the asymmetric insertion of proteins and lipids has been put on firm experimental ground. At higher molecular resolution it has been possible to provide a detailed pi2ture of the molecular conformation and dynamics of lipids and, to some extent, even of small peptides embedded in a bilayer matrix. Many of these achieve ments would not have been possible without the application of modem spectroscopic methods. Since these techniques are scattered in a variety of specialized textbooks the present monograph attempts to describe the key spectroscopic methods employed in present-day membrane research at an intermediate level. There is no question that the elusive detailed structure of the biological membrane demands a multiplicity of experi mental approaches and that no single spectroscopic method can cover the full range of physical phenomena encountered in a membrane. Much confusion in the literature has arisen by undue generalizations without considering the frequency range or other limi tations of the methods employed. It is to be hoped that the present monograph with its comprehensive description of most modem spectroscopic techniques, will contribute to- .