Mhc Ligands And Peptide Motifs

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MHC Ligands and Peptide Motifs

Hans-Georg Rammensee,Jutta Bachmann,Stefan Stevanovic
MHC Ligands and Peptide Motifs Book PDF

Author : Hans-Georg Rammensee,Jutta Bachmann,Stefan Stevanovic
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 54,9 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9783662221624

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MHC Ligands and Peptide Motifs by Hans-Georg Rammensee,Jutta Bachmann,Stefan Stevanovic Pdf

This book is centered on a comprehensive list of MHC peptide motifs and ligands as known to date, together with selected T cell epitopes, arranged in an easy-to-read fashion. This information is put into context by chapters on MHC gene organization, MHC structure, T cell epitope prediction, antigen processing and T cell responses. In addition, the book provides a great deal of complementary information: amino acid sequences of MHC class I alpha1 and alpha2 domains and of class II alpha1 and beta1 domains, the established or predicted composition and specificity of MHC pockets, notes on MHC nomenclature including old assignments and reference to useful internet addresses. A handy reference manual that should be helpful for all those dealing with MHC-associated peptides.

Antigen Processing

Peter van Endert
Antigen Processing Book PDF

Author : Peter van Endert
Publisher : Humana Press
Page : 0 pages
File Size : 46,9 Mb
Release : 2013-01-18
Category : Medical
ISBN : 1627032177

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Antigen Processing by Peter van Endert Pdf

Antigen processing is a biological process that prepares antigens for the presentation to special cells in the immune system called T lymphocytes. In Antigen Processing: Methods and Protocols, expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing events, ending with recognition of peptide-MHC complexes at the cell surface by T lymphocytes. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antigen Processing: Methods and Protocols is designed for beginners and experts interested in studying antigen processing.

Janeway's Immunobiology

Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Janeway s Immunobiology Book PDF

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 45,8 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Bioinformatics

Venkatarajan Mathura,Pandjassarame Kangueane
Bioinformatics Book PDF

Author : Venkatarajan Mathura,Pandjassarame Kangueane
Publisher : Springer Science & Business Media
Page : 196 pages
File Size : 44,6 Mb
Release : 2008-10-11
Category : Science
ISBN : 9780387848709

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Bioinformatics by Venkatarajan Mathura,Pandjassarame Kangueane Pdf

Bioinformatics is an evolving field that is gaining popularity due to genomics, proteomics and other high-throughput biological methods. The function of bioinformatic scientists includes biological data storage, retrieval and in silico analysis of the results from large-scale experiments. This requires a grasp of knowledge mining algorithms, a thorough understanding of biological knowledge base, and the logical relationship of entities that describe a process or the system. Bioinformatics researchers are required to be trained in multidisciplinary fields of biology, mathematics and computer science. Currently the requirements are satisfied by ad hoc researchers who have specific skills in biology or mathematics/computer science. But the learning curve is steep and the time required to communicate using domain specific terms is becoming a major bottle neck in scientific productivity. This workbook provides hands-on experience which has been lacking for qualified bioinformatics researchers.

Polypeptide

Usman Sumo Friend Tambunan
Polypeptide Book PDF

Author : Usman Sumo Friend Tambunan
Publisher : BoD – Books on Demand
Page : 90 pages
File Size : 54,5 Mb
Release : 2018-08-16
Category : Science
ISBN : 9781789234640

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Polypeptide by Usman Sumo Friend Tambunan Pdf

Peptides are the biomolecules that consist of several amino acid chains linked through peptide bonds. This class of biomolecules is commonly found in living matter, and some of which play an imperative role in their regulation and functional activities. Peptides have been extensively applied in every aspect of human life, including cosmetics, electronics, the food industries, and pharmaceutical fields. Ultimately, peptide commercialization has become a major trend, which has been growing significantly in recent years. Viewed from the scientific perspective described above, the editor believes that the development of peptides in every aspect of human life should be accelerated. As such, this book aims to provide insight and knowledge regarding the current research that has been conducted in this field; hence, this book may encourage the reader to emphasize the importance of peptides in human life and to inspire others to identify the potency of peptides for other applications that still need further exploration. In this book, some of the compelling applications of peptides in biological and health sciences will be introduced. This book comprises an introductory chapter, along with four chapters presented by several prominent scientists who work in the field of peptide research.

Immunology of Infection

Stefan H.E. Kaufmann,Dieter Kabelitz
Immunology of Infection Book PDF

Author : Stefan H.E. Kaufmann,Dieter Kabelitz
Publisher : Gulf Professional Publishing
Page : 844 pages
File Size : 54,5 Mb
Release : 2002-12-19
Category : Medical
ISBN : 0125215320

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Immunology of Infection by Stefan H.E. Kaufmann,Dieter Kabelitz Pdf

Immunology of Infection, 2nd Edition, edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the Microbiologist interested in analysing host-pathogen relationships, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology. This new edition of Immunology of Infection provides ready-to-use "recipes", and the latest emerging techniques as well as novel approaches to the tried and tested, established methods included in the successful first edition. Methods in Microbiologyis the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research. Includes techniques for genome-wide expression profiling of both the pathogen and host and of the host response to infection Cytometric analysis of cytokine secretion by immune cells Describes tetramer technology for the quantitative analysis of antigen specific T cell responses Analysis of host cells and pathogens involved in the host-microbe interplay Covers techniques useful for the analysis of human and murine systems Includes techniques for the prediction and determination of MHC ligands and T cell epitopes Covers the fundamentals and practice of DNA vaccines Describes methods for the isolation and propagation of human dendritic cells

Immunoinformatics

Christian Schönbach,Shoba Ranganathan,Vladimir Brusic
Immunoinformatics Book PDF

Author : Christian Schönbach,Shoba Ranganathan,Vladimir Brusic
Publisher : Springer Science & Business Media
Page : 216 pages
File Size : 54,6 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9780387729688

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Immunoinformatics by Christian Schönbach,Shoba Ranganathan,Vladimir Brusic Pdf

In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

The HLA FactsBook

Steven G.E. Marsh,Peter Parham,Linda D. Barber
The HLA FactsBook Book PDF

Author : Steven G.E. Marsh,Peter Parham,Linda D. Barber
Publisher : Elsevier
Page : 416 pages
File Size : 52,5 Mb
Release : 1999-12-13
Category : Medical
ISBN : 0080542506

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The HLA FactsBook by Steven G.E. Marsh,Peter Parham,Linda D. Barber Pdf

The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references

Immunoinformatics

Gregory R. Bock,Jamie A. Goode
Immunoinformatics Book PDF

Author : Gregory R. Bock,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 45,6 Mb
Release : 2004-03-05
Category : Medical
ISBN : 9780470090756

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Immunoinformatics by Gregory R. Bock,Jamie A. Goode Pdf

The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems. This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics. The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research. Related Novartis Foundation symposia: 247 In Silico Simulation of Biological Processes Chair: Denis Noble 252 Generation and effector functions of regulatory lymphocytes Chair: Jean-François Bach

Bioinformatics Research and Applications

Ion Măndoiu,Alexander Zelikovsky
Bioinformatics Research and Applications Book PDF

Author : Ion Măndoiu,Alexander Zelikovsky
Publisher : Springer Science & Business Media
Page : 1331 pages
File Size : 50,7 Mb
Release : 2007-04-26
Category : Science
ISBN : 9783540720300

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Bioinformatics Research and Applications by Ion Măndoiu,Alexander Zelikovsky Pdf

This book constitutes the refereed proceedings of the Third International Symposium on Bioinformatics Research and Applications, ISBRA 2007, held in Atlanta, GA, USA in May 2007. The 55 revised full papers presented together with three invited talks cover a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

Immunoinformatics

Darren R. Flower
Immunoinformatics Book PDF

Author : Darren R. Flower
Publisher : Springer Science & Business Media
Page : 436 pages
File Size : 42,7 Mb
Release : 2008-02-07
Category : Science
ISBN : 9781603271189

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Immunoinformatics by Darren R. Flower Pdf

This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. It addresses databases, HLA supertypes, MCH binding, and other properties of immune systems. The book contains chapters written by leaders in the field and provides a firm background for anyone working in immunoinformatics in one easy-to-use, insightful volume.

Bioinformation Discovery

Pandjassarame Kangueane
Bioinformation Discovery Book PDF

Author : Pandjassarame Kangueane
Publisher : Springer
Page : 202 pages
File Size : 52,5 Mb
Release : 2018-09-01
Category : Science
ISBN : 9783319953274

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Bioinformation Discovery by Pandjassarame Kangueane Pdf

This new edition continues to illustrate the power of biological data in knowledge discovery. It describes biological data types and representations with examples for creating a workflow in bioinformation discovery. The concepts in knowledge discovery from data are illustrated using line diagrams. The principles and concepts in knowledge discovery are used for the development of prediction models for simulations of biological reactions and events. Advanced topics in molecular evolution and cellular & molecular biology are addressed using bioinformation gleaned through discovery. Each chapter contains approximately 10 exercises for practice. This will help students to expand their problem solving skills in Bioinformation Discovery. In this new edition, there are three new chapters covering single nucleotide polymorphism, genes, proteins and disease, and protein functions driven by surface electrostatics.

Pattern Recognition in Bioinformatics

Jagath C.- Rajapakse,Bertil Schmidt,Gwenn Volkert
Pattern Recognition in Bioinformatics Book PDF

Author : Jagath C.- Rajapakse,Bertil Schmidt,Gwenn Volkert
Publisher : Springer
Page : 427 pages
File Size : 49,9 Mb
Release : 2007-09-19
Category : Science
ISBN : 9783540752868

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Pattern Recognition in Bioinformatics by Jagath C.- Rajapakse,Bertil Schmidt,Gwenn Volkert Pdf

This book constitutes the refereed proceedings of the International Workshop on Pattern Recognition in Bioinformatics, PRIB 2007, held in Singapore in October 2007. The 38 revised full papers presented were carefully reviewed and selected from 125 submissions. The papers discuss the applications of pattern recognition methods in the field of bioinformatics to solve problems in life sciences.

Computer and Information Sciences -- ISCIS 2006

Albert Levi
Computer and Information Sciences ISCIS 2006 Book PDF

Author : Albert Levi
Publisher : Springer Science & Business Media
Page : 1106 pages
File Size : 47,9 Mb
Release : 2006-10-24
Category : Computers
ISBN : 9783540472421

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Computer and Information Sciences -- ISCIS 2006 by Albert Levi Pdf

This book constitutes the refereed proceedings of the 21st International Symposium on Computer and Information Sciences, ISCIS 2006, held in Istanbul, Turkey in October 2006. The 106 revised full papers presented together with five invited lectures were carefully reviewed and selected from 606 submissions.

Advances in Immunology

Frederick W. Alt
Advances in Immunology Book PDF

Author : Frederick W. Alt
Publisher : Academic Press
Page : 241 pages
File Size : 46,5 Mb
Release : 2009-01-19
Category : Medical
ISBN : 9780080921723

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Advances in Immunology by Frederick W. Alt Pdf

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.