Microbial Pathogenomics

Author : Hilde de Reuse,Stefan Bereswill
Publisher : Karger Medical and Scientific Publishers
Page : 224 pages
File Size : 55,5 Mb
Release : 2009-01-01
Category : Medical
ISBN : 9783805591928

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Microbial Pathogenomics by Hilde de Reuse,Stefan Bereswill Pdf

'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'.'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.

Author : Jörg Hacker,Ulrich Dobrindt
Publisher : John Wiley & Sons
Page : 616 pages
File Size : 50,8 Mb
Release : 2006-12-13
Category : Science
ISBN : 9783527607518

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Pathogenomics by Jörg Hacker,Ulrich Dobrindt Pdf

The first book on this young, highly dynamic, and expanding field. This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures. The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis. This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.

Author : Mark J. Pallen,Karen E. Nelson,Gail M. Preston
Publisher : Unknown
Page : 488 pages
File Size : 45,5 Mb
Release : 2007
Category : Medical
ISBN : UOM:39015074270326

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Bacterial Pathogenomics by Mark J. Pallen,Karen E. Nelson,Gail M. Preston Pdf

This landmark volume details progress in the fast-changing world of bacterial genomics and it includes contributions from a team of over forty world-renowned authors.

Author : Tânia Aparecida Tardelli Gomes,Ulrich Dobrindt,Mauricio J. Farfan,Roxane M. Piazza
Publisher : Frontiers Media SA
Page : 224 pages
File Size : 42,8 Mb
Release : 2021-05-24
Category : Science
ISBN : 9782889667970

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Interaction of Pathogenic Escherichia coli with the Host: Pathogenomics, Virulence and Antibiotic Resistance by Tânia Aparecida Tardelli Gomes,Ulrich Dobrindt,Mauricio J. Farfan,Roxane M. Piazza Pdf

Author : Payam Behzadi,Biljana Carevic
Publisher : BoD – Books on Demand
Page : 112 pages
File Size : 42,5 Mb
Release : 2019-02-13
Category : Medical
ISBN : 9781789849554

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Microbiology of Urinary Tract Infections by Payam Behzadi,Biljana Carevic Pdf

Generally, in accordance with anatomical characteristics, urinary tract infections (UTIs) and in particular recurrent UTIs occur in women; in contrast, UTIs normally occur in men with different predisposing factors. There are several types of UTIs, including asymptomatic and symptomatic, complicated and uncomplicated, acute and chronic with a diversity of microbial pathogens. In pathogens, virulence factors and genes determine the type and severity of the UTIs. Obviously, UTIs are a huge problem in global public healthcare systems with a wide range of predisposing factors, including gender, microbial agent, the host's immune deficiencies, genetic diseases, catheterization, etc. The recent items determine the microbiology of UTIs. Accurate diagnosis and definitive treatment are the key to UTI reduction.

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 429 pages
File Size : 46,7 Mb
Release : 2013-05-02
Category : Science
ISBN : 9780309268196

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The Science and Applications of Microbial Genomics by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

Author : Tulasi Satyanarayana,Bhavdish Narain Johri,Subrata Kumar Das
Publisher : Springer
Page : 635 pages
File Size : 49,6 Mb
Release : 2019-07-17
Category : Science
ISBN : 9789811383151

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Microbial Diversity in Ecosystem Sustainability and Biotechnological Applications by Tulasi Satyanarayana,Bhavdish Narain Johri,Subrata Kumar Das Pdf

This book discusses microbial diversity in various habitats and environments, its role in ecosystem maintenance, and its potential applications (e.g. biofertilizers, biocatalysts, antibiotics, other bioactive compounds, exopolysaccharides etc.). The respective chapters, all contributed by renowned experts, offer cutting-edge information in the fields of microbial ecology and biogeography. The book explains the reasons behind the occurrence of various biogeographies and highlights recent tools (e.g. metagenomics) that can aid in biogeography studies by providing information on nucleic acid sequence data, thereby directly identifying microorganisms in various habitats and environments. In turn, the book describes how human intervention results in depletion of biodiversity, and how numerous hotspots are now losing their endemic biodiversity, resulting in the loss of many ecologically important microorganisms. In closing, the book underscores the importance of microbial diversity for sustainable ecosystems.

Author : Fernando Baquero,Emilio Bouza,Jose A. Gutierrez-Fuentes,Teresa M. Coque
Publisher : John Wiley & Sons
Page : 480 pages
File Size : 44,5 Mb
Release : 2020-07-10
Category : Medical
ISBN : 9781555819743

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Microbial Transmission by Fernando Baquero,Emilio Bouza,Jose A. Gutierrez-Fuentes,Teresa M. Coque Pdf

Microbial transmission, the processes by which microbes transit to new environments, is a significant and broad-reaching concept with applications throughout the biological sciences. This collection of reviews, edited by an international team of experts studying and working across a range of disciplines, explores transmission not just as an idea in disease but as a fundamental biological process that acts in all domains of nature and exerts its force on disparate size scales, from the micro to the macro, and across units of time as divergent as a single bacterial replication cycle and the entire course of evolution. In five sections, this overview Defines the concept of transmission and covers basic processes of transmission, including causality, control strategies, fitness costs, virulence, and selection Presents numerous combinations of transmission scenarios across the bacterial, animal, and human interface Examines transmission as the defining characteristic of infectious disease Presents methods for experimentally verifying and quantifying transmission episodes Concludes with important theoretical and modeling approaches Anyone studying or working in microbial colonization, evolution, pathogenicity, antimicrobial resistance, or public health will benefit from a deeper understanding of Microbial Transmission.

Author : P. Fratamico,N.W. Gunther
Publisher : Elsevier Inc. Chapters
Page : 560 pages
File Size : 47,8 Mb
Release : 2013-07-31
Category : Technology & Engineering
ISBN : 9780128089828

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Advances in microbial food safety by P. Fratamico,N.W. Gunther Pdf

Omic technologies, including genomics, proteomics and metabolomics, are used to study pathogen behavior at the molecular level and develop improved pathogen detection and typing systems. Omic technologies analyze complete or nearly complete expressions of cell functions. DNA sequencing has resulted in complete genomes of foodborne pathogens. Omic-based technologies explore biological processes in a quantitative and integrative manner. They facilitate identification of genes and proteins that contribute to survival and persistence in food and other environments, that play a role in pathogenesis and that are targets for detection methods and control strategies. Challenges that remain are performing genomic and proteomic studies in food and other complex matrices and interpreting and analyzing the data produced from these investigations to enhance food safety.

Author : Indra Mani,Vijai Singh,Khalid J. Alzahrani,Dinh-Toi Chu
Publisher : Springer Nature
Page : 369 pages
File Size : 53,6 Mb
Release : 2023-03-31
Category : Science
ISBN : 9789811993428

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Microbial Genomic Islands in Adaptation and Pathogenicity by Indra Mani,Vijai Singh,Khalid J. Alzahrani,Dinh-Toi Chu Pdf

This book elucidates the role of microbial genomic islands (GEIs) in genome stability, plasticity, evolutionary adaptation, and pathogenicity in the bacterial population. The initial chapters of the book present tools, including bioinformatics, artificial intelligence, machine learning, next-generation sequencing, and molecular biology techniques, for the analysis of the genomic islands. The book also discusses the importance of genomic islands in bacterial speciation, acquisition of genes related to resistome, nitrogen fixation, mobilomes, and nutritional fitness and adaptation. It provides recent advances in understanding microbial genomic islands' distribution, evolution, and mechanistic modes of behavior in pathogenic, non-pathogenic, and environmental species. This book is a valuable source for beginners in molecular microbiology, students, researchers, clinicians, stakeholders, and policymakers interested in understanding the role of GEIs in the adaptive evolution of microorganisms. ​

Author : Xianghe Yan
Publisher : DEStech Publications, Inc
Page : 644 pages
File Size : 40,6 Mb
Release : 2012
Category : Medical
ISBN : 9781605950471

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Omics, Microbial Modeling and Technologies for Foodborne Pathogens by Xianghe Yan Pdf

Provides comprehensive information on genetic analysis and multiple omics methods, microbial modeling, and other technologies used for the analysis of foodborne pathogens. This title details the use of genomics and other omics technologies to study and classify foodborne bacteria, viruses, fungi and protozoa.

Author : Tanveer Bilal Pirzadah,Bisma Malik,Khalid Rehman Hakeem
Publisher : CRC Press
Page : 381 pages
File Size : 50,9 Mb
Release : 2021-06-06
Category : Medical
ISBN : 9781000388961

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Plant-Microbe Dynamics by Tanveer Bilal Pirzadah,Bisma Malik,Khalid Rehman Hakeem Pdf

Key Features: Shares the latest insight on omics technologies to unravel plant-microbe dynamic interactions and other novel phytotechnologies for cleaning contaminated soils. It also provides brief insight on the recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-a genome editing tool to explore plant-microbe interactions and how this genome editing tool helps to improve the ability of microbes/plants to combat abiotic/biotic stresses.

Author : Gowhar Hamid Dar,Rouf Ahmad Bhat,Humaira Qadri,Khalid M. Al-Ghamdi,Khalid Rehman Hakeem
Publisher : Academic Press
Page : 462 pages
File Size : 48,9 Mb
Release : 2022-03-24
Category : Technology & Engineering
ISBN : 9780323856256

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Bacterial Fish Diseases by Gowhar Hamid Dar,Rouf Ahmad Bhat,Humaira Qadri,Khalid M. Al-Ghamdi,Khalid Rehman Hakeem Pdf

Bacterial Fish Diseases: Environmental and Economic Constraints will be useful for researchers and academics who need to understand the nature and consequences of bacteria-related disease in fishes. It has in-depth information on the complete genome of various bacterial species and identifies an essential number of virulence genes that affect the pathogenic potential of the bacteria in fish. Users will find the most relevant information derived from the available bacterial genomes concerning virulence and the diverse virulence factors that actively participate in host adherence, colonization and infection, including structural components, extracellular factors, secretion systems, iron acquisition and quorum sensing mechanisms. This reference is beneficial for understanding economic losses due to bacterial pathogens in fish fauna and its impact on the economy. It addition, it provides information on good aquaculture practices and how to scientifically manage aquaculture and fishery sectors. Presents bacteria-related diseases in fish species, highlighting problems associated with the culturing of fish Discusses pollution contamination in freshwater ecosystems to provide insights into the sustainable management of fish species Provides fundamental research concepts of fish health, along with practical research methods

Author : Gerhard Gottschalk
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 42,8 Mb
Release : 2012-09-12
Category : Science
ISBN : 9783527669394

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Discover the World of Microbes by Gerhard Gottschalk Pdf

This title is an essential primer for all students who need some background in microbiology and want to become familiar with the universal importance of bacteria for all forms of life. Written by Gerhard Gottschalk, Fellow of the American Academy of Microbiology and one of the most prominent microbiologists in our time, this text covers the topic in its whole breadth and does not only focus on bacteria as pathogens. The book is written in an easy-to-read, entertaining style but each chapter also contains a `facts' section with compact text and diagrams for easy learning. In addition, more than 40 famous scientists, including several Nobel Prize winners, contributed sections, written specifically for this title. The book comes with color figures and a companion website with questions and answers. Key features: Unique, introductory text offering a comprehensive overview of the astonishing variety and abilities of Bacteria Easy-to-read, fascinating and educational Written by one of the best known microbiologists of our time Color images throughout Each chapter has a compact tutorial part with schemes on the biochemistry and metabolic pathways of Bacteria Comes with a companion website with questions and answers

Author : Carlton L. Gyles,John F. Prescott,J. Glenn Songer,Charles O. Thoen
Publisher : John Wiley & Sons
Page : 674 pages
File Size : 42,9 Mb
Release : 2011-06-09
Category : Medical
ISBN : 9780470961728

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Pathogenesis of Bacterial Infections in Animals by Carlton L. Gyles,John F. Prescott,J. Glenn Songer,Charles O. Thoen Pdf

Pathogenesis of Bacterial Infections in Animals, Fourth Edition captures the rapid developments in understanding the mechanisms of virulence of the major bacterial pathogens of animals. Now including a color plate section, the book presents an overview of pathogenesis, including relevant events that occur in the herd or flock and its environment, and activities that take place at the cellular and molecular levels. With contributions from 64 experts in the field, this book serves as a great reference for graduate students in veterinary medicine and animal science, microbiologists, virologists and pathologists.