Microfluidics And Biosensors In Cancer Research

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Microfluidics and Biosensors in Cancer Research

David Caballero,Subhas C. Kundu,Rui L. Reis
Microfluidics and Biosensors in Cancer Research Book PDF

Author : David Caballero,Subhas C. Kundu,Rui L. Reis
Publisher : Springer Nature
Page : 599 pages
File Size : 42,5 Mb
Release : 2022-06-27
Category : Medical
ISBN : 9783031040399

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Microfluidics and Biosensors in Cancer Research by David Caballero,Subhas C. Kundu,Rui L. Reis Pdf

This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.

Biosensors and Cancer

Victor R. Preedy,Vinood Patel
Biosensors and Cancer Book PDF

Author : Victor R. Preedy,Vinood Patel
Publisher : CRC Press
Page : 426 pages
File Size : 54,8 Mb
Release : 2012-07-27
Category : Medical
ISBN : 9781578087341

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Biosensors and Cancer by Victor R. Preedy,Vinood Patel Pdf

Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.

Microfluidic Biosensors

Wing Cheung Mak,Aaron Ho Pui Ho
Microfluidic Biosensors Book PDF

Author : Wing Cheung Mak,Aaron Ho Pui Ho
Publisher : Elsevier
Page : 370 pages
File Size : 51,5 Mb
Release : 2022-11-05
Category : Technology & Engineering
ISBN : 9780128238479

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Microfluidic Biosensors by Wing Cheung Mak,Aaron Ho Pui Ho Pdf

Microfluidic Biosensors provides a comprehensive overview covering the most recent emerging technologies on the design, fabrication, and integration of microfluidics with transducers. These form various integrated microfluidic biosensors with device configurations ranging from 2D to 4D levels. Coverage also includes advanced printed microfluidic biosensors, flexible microfluidics for wearable biosensors, autonomous lab-on-a-chip biosensors, CMOS-base microanalysis systems, and microfluidic devices for mobile phone biosensing. The editors and contributors of this book represent both academia and industry, come from a varied range of backgrounds, and offer a global perspective. This book discusses the design and principle of microfluidic systems and uses them for biosensing applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, providing a unique perspective and much-needed content. The editors have crafted this book to be accessible to all levels of academics from graduate students, researchers, and professors working in the fields of biosensors, microfluidics design, material science, analytical chemistry, biomedical devices, and biomedical engineering. It can also be useful for industry professionals working for microfluidic device manufacturers, or in the industry of biosensors and biomedical devices. Presents an in-depth overview of microfluidic biosensors and associated emerging technologies such as printed microfluidics and novel transducers Addresses a range of microfluidic biosensors with device configurations ranging from 2D to 4D levels Includes the commercialization aspects of microfluidic biosensors that provide insights for scientists and engineers in research and development

Biosensor Based Advanced Cancer Diagnostics

Raju Khan,Arpana Parihar,S.K. Sanghi
Biosensor Based Advanced Cancer Diagnostics Book PDF

Author : Raju Khan,Arpana Parihar,S.K. Sanghi
Publisher : Academic Press
Page : 439 pages
File Size : 45,8 Mb
Release : 2021-08-25
Category : Technology & Engineering
ISBN : 9780128236512

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Biosensor Based Advanced Cancer Diagnostics by Raju Khan,Arpana Parihar,S.K. Sanghi Pdf

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer

Advanced Microfluidics Based Point-of-Care Diagnostics

Raju Khan,Chetna Dhand,Sunil Kumar Sanghi,D. Shabi Thankaraj Salammal,Ashtbhuja Prasad Mishra
Advanced Microfluidics Based Point of Care Diagnostics Book PDF

Author : Raju Khan,Chetna Dhand,Sunil Kumar Sanghi,D. Shabi Thankaraj Salammal,Ashtbhuja Prasad Mishra
Publisher : CRC Press
Page : 416 pages
File Size : 47,5 Mb
Release : 2021-03-11
Category : Medical
ISBN : 9781000548372

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Advanced Microfluidics Based Point-of-Care Diagnostics by Raju Khan,Chetna Dhand,Sunil Kumar Sanghi,D. Shabi Thankaraj Salammal,Ashtbhuja Prasad Mishra Pdf

This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.

Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis

Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
Next Generation Point of care Biomedical Sensors Technologies for Cancer Diagnosis Book PDF

Author : Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
Publisher : Springer
Page : 396 pages
File Size : 55,7 Mb
Release : 2017-12-30
Category : Medical
ISBN : 9789811047268

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Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis by Pranjal Chandra,Yen Nee Tan,Surinder P. Singh Pdf

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Nanotechnology for Microfluidics

Xingyu Jiang
Nanotechnology for Microfluidics Book PDF

Author : Xingyu Jiang
Publisher : John Wiley & Sons
Page : 444 pages
File Size : 53,8 Mb
Release : 2020-09-08
Category : Technology & Engineering
ISBN : 9783527345335

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Nanotechnology for Microfluidics by Xingyu Jiang Pdf

The book focuses on microfluidics with applications in nanotechnology. The first part summarizes the recent advances and achievements in the field of microfluidic technology, with emphasize on the the influence of nanotechnology. The second part introduces various applications of microfluidics in nanotechnology, such as drug delivery, tissue engineering and biomedical diagnosis.

Biomedical Applications of Microfluidic Devices

Michael R. Hamblin,Mahdi Karimi
Biomedical Applications of Microfluidic Devices Book PDF

Author : Michael R. Hamblin,Mahdi Karimi
Publisher : Academic Press
Page : 352 pages
File Size : 44,6 Mb
Release : 2020-11-12
Category : Technology & Engineering
ISBN : 9780128187920

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Biomedical Applications of Microfluidic Devices by Michael R. Hamblin,Mahdi Karimi Pdf

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Biosensors and Molecular Technologies for Cancer Diagnostics

Keith E. Herold,Avraham Rasooly
Biosensors and Molecular Technologies for Cancer Diagnostics Book PDF

Author : Keith E. Herold,Avraham Rasooly
Publisher : Taylor & Francis
Page : 844 pages
File Size : 45,6 Mb
Release : 2012-05-29
Category : Science
ISBN : 9781439841662

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Biosensors and Molecular Technologies for Cancer Diagnostics by Keith E. Herold,Avraham Rasooly Pdf

Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. The book addresses cancer molecular diagnostics, including genomic and proteomic approaches, from the perspective of biosensors and biodetection. It explains how to measure and understand molecular markers using biosensors and discusses the medical advantages of rapid and accurate cancer diagnostics. It also describes optical, electrochemical, and optomechanical biosensor technologies, with a focus on cancer analysis and the clinical utility of these technologies for cancer detection, diagnostics, prognostics, and treatment. Making biosensor technology more accessible to molecular biologists, oncologists, pathologists, and engineers, this volume advances the integration of this technology into mainstream clinical practice. Through its in-depth coverage of a range of biosensors, the book shows how they can play instrumental roles in the early molecular diagnosis of cancer.

Biosensors for Single-Cell Analysis

Jian Chen,Yao Lu
Biosensors for Single Cell Analysis Book PDF

Author : Jian Chen,Yao Lu
Publisher : Academic Press
Page : 184 pages
File Size : 54,6 Mb
Release : 2021-10-26
Category : Science
ISBN : 9780323885591

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Biosensors for Single-Cell Analysis by Jian Chen,Yao Lu Pdf

Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers. Includes chapters focused on key single-cell properties, such as proteomic, metabolic and mechanical characterization Features case studies that illustrate the application of biosensors for single-cell analysis Considers microfluidic approaches for each single-cell property discussed Explores future directions for single-cell analysis and biosensor technology

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B

Anonim
Micro Nanofluidics and Lab on Chip Based Emerging Technologies for Biomedical and Translational Research Applications Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 370 pages
File Size : 43,9 Mb
Release : 2022-01-28
Category : Science
ISBN : 9780323853040

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Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B by Anonim Pdf

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B, Volume 187 represents the collation of chapters written by eminent scientists worldwide. Chapters in this new release include Design and fabrication of microfluidics devices for molecular biology applications, Micro/Nanofluidics devices for drug delivery, From organ-on-chip to body-on-chip: the next generation of microfluidics platforms for in vitro drug toxicity testing, Micro/Nanofluidics for high throughput drug screening, Design, fabrication and assembly of lab-on-a-chip and its uses, Advances in microfluidic 3D cell culture for pre-clinical drug development, Tissue and organ culture on lab-on-a chip for biomedical applications, and much more. Offers a basic understanding of the state-of-the-art design and fabrication of microfluidics/ nanofluidics and lab on chip Explains how to develop microfluidics/nanofluidic for advanced application such as healthcare, high throughout drug screening, 3D cell culture and organ-on-chip Discusses the emerging demands and research of micro/nanofluidic based devices in biomedical and translational research applications

Cell Analysis on Microfluidics

Jin-Ming Lin
Cell Analysis on Microfluidics Book PDF

Author : Jin-Ming Lin
Publisher : Springer
Page : 429 pages
File Size : 54,5 Mb
Release : 2017-10-25
Category : Science
ISBN : 9789811053948

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Cell Analysis on Microfluidics by Jin-Ming Lin Pdf

This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.

Next-Generation Smart Biosensing

Kamil Reza Khondakar,Ajeet Kumar Kaushik
Next Generation Smart Biosensing Book PDF

Author : Kamil Reza Khondakar,Ajeet Kumar Kaushik
Publisher : Elsevier
Page : 344 pages
File Size : 41,7 Mb
Release : 2024-01-14
Category : Science
ISBN : 9780323972727

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Next-Generation Smart Biosensing by Kamil Reza Khondakar,Ajeet Kumar Kaushik Pdf

Quantum Sensing at the Interface of Nanotechnology Integrated Microfluidics provides broad multidisciplinary coverage of innovative quantum sensing technologies suitable to industries in the engineering, biomedical, healthcare and environmental sectors. Sections discuss emerging quantum sensing and with an introduction to microfluidic devices, smart sensors, the role of nanotechnology, smart sensing, and the role of quantum technology and artificial intelligence for nano-enabled microfluidics. Sensing technologies and nano-enabled microfluidics and their biomedical and industrial applications are explored. This will be a useful resource for those in research and industry interested in biotechnology, nanotechnology, sensing technology and their applications in multidisciplinary fields. Provides an introduction to the types of microfluidic devices, smart sensors, and the role of nanotechnology Covers smart sensing for multidisciplinary sectors Explores the challenges and prospects of nano-microfluidics systems

Biosensors and Nanotechnology

Zeynep Altintas
Biosensors and Nanotechnology Book PDF

Author : Zeynep Altintas
Publisher : John Wiley & Sons
Page : 421 pages
File Size : 47,7 Mb
Release : 2017-12-18
Category : Technology & Engineering
ISBN : 9781119065012

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Biosensors and Nanotechnology by Zeynep Altintas Pdf

Provides a broad range of information from basic principles to advanced applications of biosensors and nanomaterials in health care diagnostics This book utilizes a multidisciplinary approach to provide a wide range of information on biosensors and the impact of nanotechnology on the development of biosensors for health care. It offers a solid background on biosensors, recognition receptors, biomarkers, and disease diagnostics. An overview of biosensor-based health care applications is addressed. Nanomaterial applications in biosensors and diagnostics are included, covering the application of nanoparticles, magnetic nanomaterials, quantum dots, carbon nanotubes, graphene, and molecularly imprinted nanostructures. The topic of organ-specific health care systems utilizing biosensors is also incorporated to provide deep insight into the very recent advances in disease diagnostics. Biosensors and Nanotechnology: Applications in Health Care Diagnostics is comprised of 15 chapters that are presented in four sections and written by 33 researchers who are actively working in Germany, the United Kingdom, Italy, Turkey, Denmark, Finland, Romania, Malaysia and Brazil. It covers biomarkers in healthcare; microfluidics in medical diagnostics; SPR-based biosensor techniques; piezoelectric-based biosensor technologies; MEMS-based cell counting methods; lab-on-chip platforms; optical applications for cancer cases; and more. Discusses the latest technology and advances in the field of biosensors and their applications for healthcare diagnostics Particular focus on biosensors for cancer Summarizes research of the last 30 years, relating it to state-of-the-art technologies Biosensors and Nanotechnology: Applications in Health Care Diagnostics is an excellent book for researchers, scientists, regulators, consultants, and engineers in the field, as well as for graduate students studying the subject.

Electrochemical Biosensors

Serge Cosnier
Electrochemical Biosensors Book PDF

Author : Serge Cosnier
Publisher : CRC Press
Page : 412 pages
File Size : 40,5 Mb
Release : 2015-01-26
Category : Science
ISBN : 9789814411479

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Electrochemical Biosensors by Serge Cosnier Pdf

Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analytical chemistry. In particular, electrochemistry has played a pivotal role in the development of transduction methods for biological processes and biosensors. In parallel, the explosion of activity in nanoscience and nanotechnology and their huge success have profoundly affected biosensor technology, opening new avenues of research for electrode materials and transduction. This book provides an overview of biosensors based on amperometry, conductimetry, potentiometry, square-wave voltammetry, impedance, and electrochemiluminescence and describes the use of ultramicroelectrodes for the real-time monitoring and understanding of exocytosis. Areas of particular interest are the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Moreover, advanced insights in the innovative concept of self-powered biosensors derived from biofuel cells are also discussed.