Next Generation Point Of Care Biomedical Sensors Technologies For Cancer Diagnosis

Author : Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
Publisher : Springer
Page : 396 pages
File Size : 41,6 Mb
Release : 2017-12-30
Category : Medical
ISBN : 9789811047268

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Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis by Pranjal Chandra,Yen Nee Tan,Surinder P. Singh Pdf

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Author : Ahmed Barhoum,Zeynep Altintas
Publisher : Elsevier
Page : 970 pages
File Size : 50,5 Mb
Release : 2022-11-16
Category : Science
ISBN : 9780323902236

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Advanced Sensor Technology by Ahmed Barhoum,Zeynep Altintas Pdf

Advanced Sensor Technology: Biomedical, Environmental, and Construction Applications introduces readers to the past, present and future of sensor technology and its emerging applications in a wide variety of different fields. Organized in five parts, the book covers historical context and future outlook of sensor technology development and emerging applications, the use of sensors throughout many applications in healthcare, health and life science research, public health and safety, discusses chemical sensors used in environmental monitoring and remediation of contaminants, highlights the use of sensors in food, agriculture, fire prevention, automotive and robotics, and more. Final sections look forward at the challenges that must be overcome in the development and use of sensing technology as well as their commercial use, making this book appropriate for the interdisciplinary community of researchers and practitioners interested in the development of sensor technologies. Covers a range of environmental applications such as protection and improvement of water, air, soil, plants, and agriculture and food production; biomedical applications including detection of viruses, genes, hormones, proteins, bacteria, and cancer, and applications in construction such as fire protection, automotive, robotics, food packing and micro-machining Provides an outlook on opportunities and challenges for the fabrication and manufacturing of sensors in industry and their applicability for industrial uses Demonstrates how cutting-edge developments in sensing technology translate into real-world innovations in a range of industry sectors

Author : Pankaj Suman,Pranjal Chandra
Publisher : Springer Nature
Page : 245 pages
File Size : 41,8 Mb
Release : 2020-10-12
Category : Medical
ISBN : 9789811558238

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Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing by Pankaj Suman,Pranjal Chandra Pdf

This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.

Author : Gorachand Dutta
Publisher : Springer Nature
Page : 252 pages
File Size : 48,7 Mb
Release : 2022-12-02
Category : Science
ISBN : 9789811971303

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Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics by Gorachand Dutta Pdf

This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. ​

Author : Sushma Dave,Jayashankar Das,Sougata Ghosh
Publisher : Elsevier
Page : 596 pages
File Size : 53,5 Mb
Release : 2022-03-11
Category : Technology & Engineering
ISBN : 9780323900669

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Advanced Nanomaterials for Point of Care Diagnosis and Therapy by Sushma Dave,Jayashankar Das,Sougata Ghosh Pdf

Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite. Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field. Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform

Author : Raju Khan,Chetna Dhand,Sunil Kumar Sanghi,D. Shabi Thankaraj Salammal,Ashtbhuja Prasad Mishra
Publisher : CRC Press
Page : 416 pages
File Size : 48,8 Mb
Release : 2021-03-11
Category : Medical
ISBN : 9781000548372

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Advanced Microfluidics Based Point-of-Care Diagnostics by Raju Khan,Chetna Dhand,Sunil Kumar Sanghi,D. Shabi Thankaraj Salammal,Ashtbhuja Prasad Mishra Pdf

This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.

Author : Arpana Parihar,Raju Khan
Publisher : CRC Press
Page : 375 pages
File Size : 53,5 Mb
Release : 2023-12-18
Category : Technology & Engineering
ISBN : 9781003829508

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Aptasensors for Point-of-Care Diagnostics by Arpana Parihar,Raju Khan Pdf

The design and fabrication of aptamer-based biosensors for point-of-care testing of disease diagnostic and prognostic is an upthrust and interdisciplinary area of research. This book covers the design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including an understanding of health care management in terms of timely updates of disease situations in a particular geographical area. It also discusses the scaling up and market trend of aptamer-based devices for extension of research from lab to market, and end users. Features: Explains the design and fabrication of aptasensors-based diagnostic devices. Includes novel approaches and comprehensive technology overview for diagnosis management towards early-stage detection of various biomarkers associated with several health conditions. Demonstrates possible benefits of combined diagnostics and therapeutic possibilities using aptamer-based point-of-care technologies devices. Discusses emerging implications and recent advances of biosensing platforms for designing and developing aptamer-based point-of-care testing (POCT) devices. Explores aptamer-based approach to develop advanced platforms for medical applications and open arena for state-of-the-art future research. This book is aimed at researchers and graduate students in biomedical engineering, diagnostics, nanobiotechnology, and materials science.

Author : Dimitrios Nikolelis,Georgia Paraskevi Nikoleli
Publisher : CRC Press
Page : 263 pages
File Size : 40,8 Mb
Release : 2023-04-03
Category : Technology & Engineering
ISBN : 9781000887082

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Nanosensors by Dimitrios Nikolelis,Georgia Paraskevi Nikoleli Pdf

Nanotechnology and biosensors show how nanotechnology is used to create affordable, mass-produced, portable, small-sized nanosensors to directly monitor food toxicants and environmental pollutants. In addition, it provides the market with systems for applications in food analysis, environmental monitoring and health diagnostics. Nanotechnology has led to a dramatic improvement in the performance, sensitivity and selectivity of biosensor devices. Metal-oxides and carbon nanostructures, gold and magnetite nanoparticles, and the integration of dendrimers in biosensors using nanotechnology, have contributed greatly to making nanosensors more effective and affordable in the market. This book provides a timely resource on the subject.

Author : Pranjal Chandra,Rajiv Prakash
Publisher : Springer Nature
Page : 302 pages
File Size : 42,9 Mb
Release : 2020-01-25
Category : Medical
ISBN : 9789813298408

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Nanobiomaterial Engineering by Pranjal Chandra,Rajiv Prakash Pdf

This book comprehensively documents the application of Nanobiomaterials in the field of bio-medicine and diagnostics technologies by involving classical concepts/examples. Nanobiotechnology is an emerging area which encompasses all the facets of research of nano and biomaterials with their interaction with biological systems. The book briefly summarizes the various types of Nanomaterial’s, and highlights the recent developments in the synthesis of the nanomaterials for the diagnostic and therapeutic biomedical applications. It skilfully reviews the utilization of the nanomaterials alone or in combination with other bio-molecules as a contrast enhancer in in-vivo imaging, Nano-Theranostics, drug delivery, and sensing transducer matrix. It also discusses the current research on designing of the new Nanobiomaterials and their implementation in numerous fields including bio-medicine and diagnostics. Finally, it summarizes the future prospects and the commercial viability of Nanobiomaterials in the human health care.​

Author : Raju Khan,Arpana Parihar,S.K. Sanghi
Publisher : Academic Press
Page : 439 pages
File Size : 40,7 Mb
Release : 2021-08-25
Category : Technology & Engineering
ISBN : 9780128236512

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Biosensor Based Advanced Cancer Diagnostics by Raju Khan,Arpana Parihar,S.K. Sanghi Pdf

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient’s life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer

Author : Anonim
Publisher : Elsevier
Page : 480 pages
File Size : 40,7 Mb
Release : 2020-06-13
Category : Science
ISBN : 9780444643469

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Paper Based Sensors by Anonim Pdf

Paper Based Sensors, Volume 89, the latest release in this comprehensive series that gathers the most important issues relating to the design and application of these cost-effective devices used in many industries, including health and environment diagnostics, safety and security, chemistry, optics, electrochemistry, nanoscience and nanotechnologies, presents the latest updates in the field. Chapters in this new release include Exploring paper as a substrate for electrochemical micro-devices, Paper-based sensors for application in biological compound detection, Printed paper-based (bio)sensors: design, fabrication and applications, Paper-based electrochemical sensing devices, Multifarious aspects of electrochemical paper-based (bio)sensors, Paper Based Biosensors for Clinical and Biomedical Applications, and more. Provides updates on the latest design in paper-based sensors using various nano and micromaterials Includes optical/electrical-based detection modes integrated within paper-based platforms Covers applications of paper-based platforms in diagnostics and other industries

Author : Vivek Borse,Pranjal Chandra,Rohit Srivastava
Publisher : Springer Nature
Page : 380 pages
File Size : 52,8 Mb
Release : 2021-12-09
Category : Medical
ISBN : 9789811627828

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BioSensing, Theranostics, and Medical Devices by Vivek Borse,Pranjal Chandra,Rohit Srivastava Pdf

This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.

Author : R. C. Sobti
Publisher : Springer Nature
Page : 1584 pages
File Size : 41,5 Mb
Release : 2024-06-19
Category : Electronic
ISBN : 9789819962631

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Handbook of Oncobiology: From Basic to Clinical Sciences by R. C. Sobti Pdf

Author : Pranjal Chandra,Sharmili Roy
Publisher : Springer Nature
Page : 199 pages
File Size : 51,5 Mb
Release : 2020-12-04
Category : Medical
ISBN : 9789811560064

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Diagnostic Strategies for COVID-19 and other Coronaviruses by Pranjal Chandra,Sharmili Roy Pdf

This book provides fundamental information on various techniques for the detection of SARS-CoV-2 including reverse transcriptase (RT) PCR, loop-mediated isothermal amplification, immunodiagnostic tests, and CRISPR-Cas. It reviews various testing kits and detection methodologies that are currently being used for the detection of SARS-CoV-2 and examines strategies for the post-treatment detection and monitoring of SARS-CoV-2. Further, it assesses the diagnostic potential of several SARS-CoV-2 proteins; and analyzes their structural determinants and immunogenicity. In turn, the book evaluates the potential of CRISPR-Cas 12-based assays for the detection of SARS-CoV-2 using RNA extracted from patients. Lastly, it discusses the use of miniaturized biosensors for the detection of other types of coronavirus.

Author : Suresh Kaushik,Vijay Soni,Efstathia Skotti
Publisher : CRC Press
Page : 414 pages
File Size : 54,5 Mb
Release : 2022-08-18
Category : Science
ISBN : 9781000684247

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Nanosensors for Futuristic Smart and Intelligent Healthcare Systems by Suresh Kaushik,Vijay Soni,Efstathia Skotti Pdf

The book, Nanosensors for Futuristic Smart and Intelligent Healthcare Systems, presents a treatise on nanosensors technology including wearables, implantable devices and wireless tools. The recent pandemic (COVID-19) has changed the behaviour of people towards diagnosis of infectious diseases and monitoring remote patient health status in real-time. The main focus of this book is the basic concepts of nanomaterials and sensing paradigms for medical devices based on nanosensor technology. The book will be valuable to researchers, engineers and scientists interested in the field of healthcare for monitoring health status in real-time.