Microfluidics For Biotechnology

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Microfluidics for Biotechnology

Jean Berthier,Pascal Silberzan
Microfluidics for Biotechnology Book PDF

Author : Jean Berthier,Pascal Silberzan
Publisher : Artech House
Page : 503 pages
File Size : 46,5 Mb
Release : 2010
Category : Science
ISBN : 9781596934443

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Microfluidics for Biotechnology by Jean Berthier,Pascal Silberzan Pdf

The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Now in a newly revised and expanded second edition, the Artech House bestseller, Microfluidics for Biotechnology brings you to the cutting edge of this burgeoning field. Among the numerous updates, the second edition features three entirely new chapters on: non-dimensional numbers in microfluidics; interface, capillarity and microdrops; and digital, two-phase and droplet microfluidics.Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. You gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and discrete Monte-Carlo methods.This unique volume describes the transport and dispersion of biochemical species and particles. You learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps you master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.

Microfluidics in Biotechnology

Janina Bahnemann,Alexander Grünberger
Microfluidics in Biotechnology Book PDF

Author : Janina Bahnemann,Alexander Grünberger
Publisher : Springer Nature
Page : 383 pages
File Size : 54,7 Mb
Release : 2022-07-28
Category : Science
ISBN : 9783031041884

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Microfluidics in Biotechnology by Janina Bahnemann,Alexander Grünberger Pdf

This new volume introduces the applications of microfluidic systems to facilitate biotechnological and biomedical processes. It provides an overview on cutting-edge technologies, summarizes traditional and modern fabrication methods and highlights recent advances regarding the application of lab-on-a-chip (LoC) systems for bioanalytical purposes. This book is ideal for research scientists and students interested at the cross-section between biotechnology, chemistry and chemical engineering.

Microfluidics for Biological Applications

Wei-Cheng Tian,Erin Finehout
Microfluidics for Biological Applications Book PDF

Author : Wei-Cheng Tian,Erin Finehout
Publisher : Springer Science & Business Media
Page : 429 pages
File Size : 46,5 Mb
Release : 2009-03-02
Category : Technology & Engineering
ISBN : 9780387094809

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Microfluidics for Biological Applications by Wei-Cheng Tian,Erin Finehout Pdf

Microfluidics for Biological Applications provides researchers and scientists in the biotechnology, pharmaceutical, and life science industries with an introduction to the basics of microfluidics and also discusses how to link these technologies to various biological applications at the industrial and academic level. Readers will gain insight into a wide variety of biological applications for microfluidics. The material presented here is divided into four parts, Part I gives perspective on the history and development of microfluidic technologies, Part II presents overviews on how microfluidic systems have been used to study and manipulate specific classes of components, Part III focuses on specific biological applications of microfluidics: biodefense, diagnostics, high throughput screening, and tissue engineering and finally Part IV concludes with a discussion of emerging trends in the microfluidics field and the current challenges to the growth and continuing success of the field.

Microfluidics and BioMEMS Applications

Francis E. H. Tay
Microfluidics and BioMEMS Applications Book PDF

Author : Francis E. H. Tay
Publisher : Springer Science & Business Media
Page : 346 pages
File Size : 45,9 Mb
Release : 2013-04-17
Category : Technology & Engineering
ISBN : 9781475735345

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Microfluidics and BioMEMS Applications by Francis E. H. Tay Pdf

Microfluidics and BioMEMS Applications central idea is on microfluidics, a relatively new research field which finds its niche in biomedical devices, especially on lab-on-a-chip and related products. Being the essential component in providing driving fluidic flows, an example of micropump is chosen to illustrate a complete cycle in development of microfluidic devices which include literature review, designing and modelling, fabrication and testing. A few articles are included to demonstrate the idea of tackling this research problem, and they cover the main development scope discussed earlier as well as other advanced modelling schemes for microfluidics and beyond. Scientists and students working in the areas of MEMS and microfluidics will benefit from this book, which may serve both communities as both a reference monograph and a textbook for courses in numerical simulation, and design and development of microfluidic devices.

Microfluidics for Biologists

Chandra K. Dixit,Ajeet Kaushik
Microfluidics for Biologists Book PDF

Author : Chandra K. Dixit,Ajeet Kaushik
Publisher : Springer
Page : 252 pages
File Size : 42,9 Mb
Release : 2016-10-13
Category : Medical
ISBN : 9783319400365

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Microfluidics for Biologists by Chandra K. Dixit,Ajeet Kaushik Pdf

This book describes novel microtechnologies and integration strategies for developing a new class of assay systems to retrieve desired health information from patients in real-time. The selection and integration of sensor components and operational parameters for developing point-of-care (POC) are also described in detail. The basics that govern the microfluidic regimen and the techniques and methods currently employed for fabricating microfluidic systems and integrating biosensors are thoroughly covered. This book also describes the application of microfluidics in the field of cell and molecular biology, single cell biology, disease diagnostics, as well as the commercially available systems that have been either introduced or have the potential of being used in research and development. This is an ideal book for aiding biologists in understanding the fundamentals and applications of microfluidics. This book also: Describes the preparatory methods for developing 3-dimensional microfluidic structures and their use for Lab-on-a-Chip design Explains the significance of miniaturization and integration of sensing components to develop wearable sensors for point-of-care (POC) Demonstrates the application of microfluidics to life sciences and analytical chemistry, including disease diagnostics and separations Motivates new ideas related to novel platforms, valving technology, miniaturized transduction methods, and device integration to develop next generation sequencing Discusses future prospects and challenges of the field of microfluidics in the areas of life sciences in general and diagnostics in particular

Microfluidics

Abhay Andar,Benjamin Adelstein,Michael Adelstein
Microfluidics Book PDF

Author : Abhay Andar,Benjamin Adelstein,Michael Adelstein
Publisher : de Gruyter
Page : 400 pages
File Size : 48,6 Mb
Release : 2020-09-29
Category : Electronic
ISBN : 3110636158

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Microfluidics by Abhay Andar,Benjamin Adelstein,Michael Adelstein Pdf

This book covers the impact of microfluidics on the field of Biotechnology, including biologics manufacturing, biosensors, macromolecule purification, nucleotide sequencing, organs-on-a-chip, and stem cell manufacturing. The authors, coming from both academia and industry, provide an in-depth look into the economics, manufacturing, scale-up, regulatory affairs and future outlook for microfluidic technologies.

Micro-Drops and Digital Microfluidics

Jean Berthier
Micro Drops and Digital Microfluidics Book PDF

Author : Jean Berthier
Publisher : William Andrew
Page : 560 pages
File Size : 51,6 Mb
Release : 2012-12-31
Category : Science
ISBN : 9781455728008

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Micro-Drops and Digital Microfluidics by Jean Berthier Pdf

In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics

Microfluidic Methods for Molecular Biology

Chang Lu,Scott S. Verbridge
Microfluidic Methods for Molecular Biology Book PDF

Author : Chang Lu,Scott S. Verbridge
Publisher : Springer
Page : 376 pages
File Size : 52,9 Mb
Release : 2016-05-14
Category : Medical
ISBN : 9783319300191

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Microfluidic Methods for Molecular Biology by Chang Lu,Scott S. Verbridge Pdf

This book covers the state-of-the-art research on molecular biology assays and molecular techniques enabled or enhanced by microfluidic platforms. Topics covered include microfluidic methods for cellular separations and single cell studies, droplet-based approaches to study protein expression and forensics, and microfluidic in situ hybridization for RNA analysis. Key molecular biology studies using model organisms are reviewed in detail. This is an ideal book for students and researchers in the microfluidics and molecular biology fields as well as engineers working in the biotechnology industry. This book also: Reviews exhaustively the latest techniques for single-cell genetic, epigenetic, metabolomic, and proteomic analysis Illustrates microfluidic approaches for inverse metabolic engineering, as well as analysis of circulating exosomes Broadens readers’ understanding of microfluidics convection-based PCR technology, microfluidic RNA-seq, and microfluidics for robust mobile diagnostics

Open Microfluidics

Jean Berthier,Kenneth A. Brakke,Erwin Berthier
Open Microfluidics Book PDF

Author : Jean Berthier,Kenneth A. Brakke,Erwin Berthier
Publisher : John Wiley & Sons
Page : 336 pages
File Size : 48,7 Mb
Release : 2016-07-20
Category : Science
ISBN : 9781118720820

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Open Microfluidics by Jean Berthier,Kenneth A. Brakke,Erwin Berthier Pdf

Open microfluidics or open-surface is becoming fundamental in scientific domains such as biotechnology, biology and space. First, such systems and devices based on open microfluidics make use of capillary forces to move fluids, without any need for external energy. Second, the “openness” of the flow facilitates the accessibility to the liquid in biotechnology and biology, and reduces the weight in space applications. This book has been conceived to give the reader the fundamental basis of open microfluidics. It covers successively The theory of spontaneous capillary flow, with the general conditions for spontaneous capillary flow, and the dynamic aspects of such flows. The formation of capillary filaments which are associated to small contact angles and sharp grooves. The study of capillary flow in open rectangular, pseudo-rectangular and trapezoidal open microchannels. The dynamics of open capillary flows in grooves with a focus on capillary resistors. The case of very viscous liquids is analyzed. An analysis of suspended capillary flows: such flows move in suspended channels devoid of top cover and bottom plate. Their accessibility is reinforced, and such systems are becoming fundamental in biology. An analysis of “rails” microfluidics, which are flows that move in channels devoid of side walls. This geometry has the advantage to be compatible with capillary networks, which are now of great interest in biotechnology, for molecular detection for example. Paper-based microfluidics where liquids wick flat paper matrix. Applications concern bioassays such as point of care devices (POC). Thread-based microfluidics is a new domain of investigation. It is seeing presently many new developments in the domain of separation and filtration, and opens the way to smart bandages and tissue engineering. The book is intended to cover the theoretical aspects of open microfluidics, experimental approaches, and examples of application.

Biological Applications of Microfluidics

Frank A. Gomez
Biological Applications of Microfluidics Book PDF

Author : Frank A. Gomez
Publisher : John Wiley & Sons
Page : 562 pages
File Size : 55,9 Mb
Release : 2008-02-15
Category : Science
ISBN : 9780470074831

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Biological Applications of Microfluidics by Frank A. Gomez Pdf

Microfluidics has numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture. This book details recent advances in the biological applications of microfluidics, including cell sorting, DNA sequencing on-a-chip, microchip capillary electrophoresis, and synthesis on a microfluidic format. It covers microfabricated LOC technologies, advanced microfluidic tools, microfluidic culture platforms for stem cell and neuroscience research, and more. This is an all-in-one, hands-on resource for analytical chemists and researchers and an excellent text for students.

Advances in Microfluidics

Xiao-Ying Yu
Advances in Microfluidics Book PDF

Author : Xiao-Ying Yu
Publisher : BoD – Books on Demand
Page : 424 pages
File Size : 43,5 Mb
Release : 2016-11-23
Category : Science
ISBN : 9789535127857

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Advances in Microfluidics by Xiao-Ying Yu Pdf

Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

Microfluidic Systems for Cancer Diagnosis

Jose L. Garcia-Cordero,Alexander Revzin
Microfluidic Systems for Cancer Diagnosis Book PDF

Author : Jose L. Garcia-Cordero,Alexander Revzin
Publisher : Springer Nature
Page : 327 pages
File Size : 49,6 Mb
Release : 2023-06-10
Category : Medical
ISBN : 9781071632710

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Microfluidic Systems for Cancer Diagnosis by Jose L. Garcia-Cordero,Alexander Revzin Pdf

This detailed volume explores recent developments in microfluidics technologies for cancer diagnosis and monitoring. The book is divided into two sections that delve into techniques for liquid biopsy for cancer diagnosis and platforms for precision oncology or personalized medicine in order to create effective patient avatars for testing anti-cancer drugs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microfluidic Systems for Cancer Diagnosis serves as an ideal guide that will be helpful to either replicate the construction of microfluidic devices specifically developed for cancer diagnosis or to catalyze development of new and better cancer diagnostic devices.

Microfluidic Technologies for Human Health

Utkan Demirci,Robert Langer,Ali Khademhosseini,Jeffrey Blander
Microfluidic Technologies for Human Health Book PDF

Author : Utkan Demirci,Robert Langer,Ali Khademhosseini,Jeffrey Blander
Publisher : World Scientific
Page : 495 pages
File Size : 46,8 Mb
Release : 2012
Category : Medical
ISBN : 9789814405515

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Microfluidic Technologies for Human Health by Utkan Demirci,Robert Langer,Ali Khademhosseini,Jeffrey Blander Pdf

Ch. 1. A microscale bioinspired cochlear-like sensor / Robert D. White, Robert Littrell, and Karl Grosh -- ch. 2. Systematic evaluation of the efficiencies of proteins and chemicals in pharmaceutical applications / Morgan Hamon and Jong Wook Hong -- ch. 3. Microfluidic glucose sensors / Jithesh V. Veetil [und weitere] -- ch. 4. Applications of microfabrication and microfluidic techniques in mesenchymal stem cell research / Abhijit Majumder [und weitere] -- ch. 5. Patient-specific modeling of low-density lipoprotein transport in coronary arteries / Ufuk Olgac -- ch. 6. Point-of-care microdevices for global health diagnostics of infectious diseases / Sau Yin Chin [und weitere] -- ch. 7. Integrated microfluidic sample preparation for chip-based molecular diagnostics / Jane Y. Zhang [und weitere] -- ch. 8. Microfluidic devices for cellular proteomic studies / Yihong Zhan and Chang Lu -- ch. 9. Microfluidics for neuroscience: novel tools and future implications / Vivian M. Hernandez and P. Hande Ozdinler -- ch. 10. Microfluidics: on-chip platforms as in vitro disease models / Shan Gao, Erkin Seker, and Martin L. Yarmush -- ch. 11. Application of microfluidics in stem cell and tissue engineering / Sasha H. Bakhru, Christopher Highley, and Stefan Zappe -- ch. 12. Microfluidic "on-the-fly" fabrication of microstructures for biomedical applications / Edward Kang, Sau Fung Wong, and Sang-Hoon Lee -- ch. 13. Microfluidics as a promising tool toward distributed viral detection / Elodie Sollier and Dino Di Carlo -- ch. 14. Electrophoresis and dielectrophoresis for lab-on-a-chip (LOC) analyses / Yagmur Demircan, Gurkan Yilmaz, and Haluk Kulah -- ch. 15. Ultrasonic embossing of carbon nanotubes for the fabrication of polymer microfluidic chips for DNA sample purification / Puttachat Khuntontong, Min Gong, and Zhiping Wang -- ch. 16. Ferrofluidics / A. Rezzan Kose and Hur Koser -- ch. 17. Antibody-based blood bioparticle capture and separation using microfluidics for global health / ZhengYuan Luo [und weitere] -- ch. 18. Applications of quantum dots for fluorescence imaging in biomedical research / ShuQi Wang [und weitere]

Microfluidics Based Microsystems

S. Kakaç,B. Kosoy,D. Li,A. Pramuanjaroenkij
Microfluidics Based Microsystems Book PDF

Author : S. Kakaç,B. Kosoy,D. Li,A. Pramuanjaroenkij
Publisher : Springer Science & Business Media
Page : 622 pages
File Size : 49,6 Mb
Release : 2010-09-10
Category : Science
ISBN : 9789048190317

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Microfluidics Based Microsystems by S. Kakaç,B. Kosoy,D. Li,A. Pramuanjaroenkij Pdf

This volume contains an archival record of the NATO Advanced Study Institute on Microfluidics Based Microsystems – Fundamentals and App- cations held in Çe ?me-Izmir, Turkey, August 23–September 4, 2009. ASIs are intended to be high-level teaching activity in scientific and technical areas of current concern. In this volume, the reader may find interesting chapters and various microsystems fundamentals and applications. As the world becomes increasingly concerned with terrorism, early - spot detection of terrorist’s weapons, particularly bio-weapons agents such as bacteria and viruses are extremely important. NATO Public Diplomacy division, Science for Peace and Security section support research, Advanced Study Institutes and workshops related to security. Keeping this policy of NATO in mind, we made such a proposal on Microsystems for security. We are very happy that leading experts agreed to come and lecture in this important NATO ASI. We will see many examples that will show us Microfluidics usefulness for rapid diagnostics following a bioterrorism attack. For the applications in national security and anti-terrorism, microfluidic system technology must meet the challenges. To develop microsystems for security and to provide a comprehensive state-of-the-art assessment of the existing research and applications by treating the subject in considerable depth through lectures from eminent professionals in the field, through discussions and panel sessions are very beneficial for young scientists in the field.

Microfluidics and Lab-on-a-Chip

Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil
Microfluidics and Lab on a Chip Book PDF

Author : Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil
Publisher : Royal Society of Chemistry
Page : 307 pages
File Size : 48,5 Mb
Release : 2020-09-24
Category : Science
ISBN : 9781782628330

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Microfluidics and Lab-on-a-Chip by Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil Pdf

Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.