Mineralocorticoids And Hypertension

Author : W. Kaufmann,G. Wambach,A. Helber,K. A. Meurer
Publisher : Springer Science & Business Media
Page : 347 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642690815

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Mineralocorticoids and Hypertension by W. Kaufmann,G. Wambach,A. Helber,K. A. Meurer Pdf

On behalf of the organizing committee of this symposium, I would like to wel come you to Cologne and thank you very much for coming. We appreciate that some of the leading scientists in the field of hypertension have accepted our invi tation to participate actively at this conference. Our first symposium on renin-angiotensin, aldosterone, and hypertension took place at Titisee in the Black Forest in 1967. The second one, on the renin-angio tensin-aldosterone system under the influence of therapeutic procedures, was held at the same place in 1970. Five years later in 1975 at a third symposium in Cologne, we discussed the problems of central nervous control of sodium balance in relation to the renin-angiotensin system. The symposium about to begin is devoted to the significance of mineralocorti coids in developing and sustaining arterial hypertension. 1) In order to provide a physiologic background for the understanding of the mechanisms involved in this complicated process, new concepts on the regulation of mineralocorticoid secretion must be discussed in detail. As the most important mineralocorticoid, aldosterone is regulated by changes in sodium and potassium homeostasis and is also influenced by adrenocorticotropic hormone (ACTH).

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 42,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Derek G. Waller,Tony Sampson
Publisher : Elsevier Health Sciences
Page : 741 pages
File Size : 41,6 Mb
Release : 2013-08-07
Category : Medical
ISBN : 9780702055034

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Medical Pharmacology and Therapeutics E-Book by Derek G. Waller,Tony Sampson Pdf

This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

Author : Karel Pacak,Graeme Eisenhofer
Publisher : Unknown
Page : 0 pages
File Size : 49,8 Mb
Release : 2002
Category : Adrenal Gland Neoplasms
ISBN : 1573314188

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Endocrine Hypertension by Karel Pacak,Graeme Eisenhofer Pdf

Several genetic, biochemical and radiologic discoveries have impacted the management of endocrine hypertension, while surgical procedures have revolutionized treatment of patients with endocrine hypertension. This text contains the proceedings of a 2001 workshop on the topic.

Author : Brian Harvey,Frederic Jaisser
Publisher : BoD – Books on Demand
Page : 302 pages
File Size : 48,8 Mb
Release : 2019-09-25
Category : Medical
ISBN : 9781839621987

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Aldosterone-Mineralocorticoid Receptor by Brian Harvey,Frederic Jaisser Pdf

This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.

Author : Christian A Koch,George P Chrousos
Publisher : Springer Science & Business Media
Page : 367 pages
File Size : 45,7 Mb
Release : 2012-08-30
Category : Medical
ISBN : 9781607615484

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Endocrine Hypertension by Christian A Koch,George P Chrousos Pdf

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.

Author : Sally Radovick,Margaret H. MacGillivray
Publisher : Springer Science & Business Media
Page : 616 pages
File Size : 43,5 Mb
Release : 2013-02-20
Category : Medical
ISBN : 9781607613954

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Pediatric Endocrinology by Sally Radovick,Margaret H. MacGillivray Pdf

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

Author : Maria I. New
Publisher : Elsevier Inc. Chapters
Page : 406 pages
File Size : 45,6 Mb
Release : 2013-08-22
Category : Medical
ISBN : 9780128072769

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Genetic Steroid Disorders by Maria I. New Pdf

This book demonstrates that each steroid disorder causing both clinical and biochemical abnormalities in patients now has a genetic basis. The genes for each step in steroidogenesis have been mapped and cloned, and the mutations in the gene causing the disorder have been described. In addition, the structural biology of the protein resulting from the mutation in the gene has been reported for many of the disorders.

Author : Ruben Vardanyan,Victor Hruby
Publisher : Academic Press
Page : 868 pages
File Size : 47,6 Mb
Release : 2016-01-07
Category : Science
ISBN : 9780124115248

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Synthesis of Best-Seller Drugs by Ruben Vardanyan,Victor Hruby Pdf

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Author : Joseph Flynn,Julie R. Ingelfinger,Ronald J. Portman
Publisher : Springer Science & Business Media
Page : 597 pages
File Size : 41,5 Mb
Release : 2013-06-26
Category : Medical
ISBN : 9781627034906

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Pediatric Hypertension by Joseph Flynn,Julie R. Ingelfinger,Ronald J. Portman Pdf

The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.

Author : Gregory Y. H. Lip,John E. Hall
Publisher : Elsevier Health Sciences
Page : 1247 pages
File Size : 55,5 Mb
Release : 2007-06-28
Category : Medical
ISBN : 9780323070676

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Comprehensive Hypertension E-Book by Gregory Y. H. Lip,John E. Hall Pdf

Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Author : Eric J. Bieber,Joseph S. Sanfilippo,Ira R. Horowitz,Mahmood I. Shafi
Publisher : Cambridge University Press
Page : 1127 pages
File Size : 47,5 Mb
Release : 2015-04-23
Category : Medical
ISBN : 9781107040397

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Clinical Gynecology by Eric J. Bieber,Joseph S. Sanfilippo,Ira R. Horowitz,Mahmood I. Shafi Pdf

Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

Author : Jonathan Elliott,Harriet M. Syme,Rosanne E. Jepson
Publisher : Springer Nature
Page : 374 pages
File Size : 42,8 Mb
Release : 2020-01-29
Category : Science
ISBN : 9783030330200

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Hypertension in the Dog and Cat by Jonathan Elliott,Harriet M. Syme,Rosanne E. Jepson Pdf

This book provides an in-depth review on various aspects of canine and feline hypertension. Physiology, pathophysiology, epidemiology and pathological consequences of high blood pressure in cats and dogs are discussed. A comparative approach is taken, the underpinning research is critically evaluated and knowledge gaps identified. In addition, the reader is presented with evidence-based treatment strategies. The book targets researchers, graduate students and clinical specialists in small animal internal medicine as well as veterinary clinicians with interest in nephrology, cardiology, neurology and ophthalmology.

Author : Edward G. Biglieri,James C. Melby
Publisher : Lippincott Williams & Wilkins
Page : 312 pages
File Size : 55,5 Mb
Release : 1990
Category : Medical
ISBN : UOM:39015015532677

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Endocrine Hypertension by Edward G. Biglieri,James C. Melby Pdf

Author : Jonathan C. Schisler,Charles H Lang,Monte Willis
Publisher : Academic Press
Page : 378 pages
File Size : 55,5 Mb
Release : 2016-10-19
Category : Medical
ISBN : 9780128031124

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Endocrinology of the Heart in Health and Disease by Jonathan C. Schisler,Charles H Lang,Monte Willis Pdf

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology