Mitogen Activated Protein Kinases

Author : Anonim
Publisher : ScholarlyEditions
Page : 48 pages
File Size : 41,5 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464940453

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Mitogen-Activated Protein Kinases: Advances in Research and Application: 2011 Edition by Anonim Pdf

Mitogen-Activated Protein Kinases: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Proline-Directed Protein Kinases in a concise format. The editors have built Mitogen-Activated Protein Kinases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proline-Directed Protein Kinases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mitogen-Activated Protein Kinases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Ritva Tikkanen,David Nikolic-Paterson
Publisher : MDPI
Page : 276 pages
File Size : 48,7 Mb
Release : 2020-06-18
Category : Science
ISBN : 9783039280704

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Mitogen Activated Protein Kinases by Ritva Tikkanen,David Nikolic-Paterson Pdf

Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.

Author : Anonim
Publisher : ScholarlyEditions
Page : 54 pages
File Size : 54,5 Mb
Release : 2013-06-21
Category : Medical
ISBN : 9781481689922

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Mitogen-Activated Protein Kinases—Advances in Research and Application: 2013 Edition by Anonim Pdf

Mitogen-Activated Protein Kinases—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about p38 Mitogen-Activated Protein Kinases in a concise format. The editors have built Mitogen-Activated Protein Kinases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about p38 Mitogen-Activated Protein Kinases in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mitogen-Activated Protein Kinases—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Ana Cuenda,José M. Lizcano,José Lozano
Publisher : Frontiers Media SA
Page : 165 pages
File Size : 41,7 Mb
Release : 2017-11-29
Category : Electronic book
ISBN : 9782889453399

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Mitogen Activated Protein Kinases by Ana Cuenda,José M. Lizcano,José Lozano Pdf

Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved in all eukaryotes and allow cells to respond to changes in the physical and chemical properties of the environment and to produce an appropriate response by altering many cellular functions. MAPKs are among the most intensively studied signal transduction systems. MAPK research is a very dynamic field in which new perspectives are continuously opening to the scientific community. Importantly, many MAPK inhibitors have been developed during the last years and are currently being tested in preclinical and clinical assays for inflammatory diseases and cancer treatment. In this research topic, we have gathered 14 papers covering recent advances in different aspects of the MAPK research area that have provided valuable insight into the spatiotemporal dynamics, the regulation and functions of MAPK pathways, as well as their therapeutic potential. We hope that this Research Topic helps readers to have a better understanding of the progresses that have been made recently in the field of MAPK signalling. A deeper understanding of the these pathways will facilitate the development of innovative therapeutic approaches.

Author : Anonim
Publisher : ScholarlyEditions
Page : 79 pages
File Size : 42,5 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481609401

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Mitogen-Activated Protein Kinases—Advances in Research and Application: 2012 Edition by Anonim Pdf

Mitogen-Activated Protein Kinases—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Mitogen-Activated Protein Kinases in a concise format. The editors have built Mitogen-Activated Protein Kinases—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mitogen-Activated Protein Kinases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mitogen-Activated Protein Kinases—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Francesc Posas,Angel R. Nebreda
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 40,8 Mb
Release : 2008-01-24
Category : Science
ISBN : 9783540755692

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Stress-Activated Protein Kinases by Francesc Posas,Angel R. Nebreda Pdf

In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.

Author : Charles K. Hester
Publisher : Unknown
Page : 0 pages
File Size : 48,6 Mb
Release : 2019
Category : Mitogen-activated protein kinases
ISBN : 1536161381

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Mitogen-activated Protein Kinases (MAPKs) by Charles K. Hester Pdf

Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation opens with a summary of the present knowledge about MAPK, with special emphasis on p38 and c-Jun N-terminal kinase. The authors focus on how these signaling pathways are engaged during some infections with intracellular parasites.The authors also describe selected regulatory aspects of circadian clocks in vertebrates, exploring an intriguing link to MAPK. Circadian clocks are time-tracking systems that provide organisms with a survival advantage.Cadmium, one of the toxic metals, is an important occupational and environmental pollutant that damages various organs, especially the kidney. The concluding study proposes that the type of kidney cell and severity of cadmium-induced cellular stress appear to determine the effect of MAPK on cell fate.

Author : Girdhar K. Pandey
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 44,9 Mb
Release : 2020-12-03
Category : Science
ISBN : 9781119541561

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Protein Kinases and Stress Signaling in Plants by Girdhar K. Pandey Pdf

A comprehensive review of stress signaling in plants using genomics and functional genomic approaches Improving agricultural production and meeting the needs of a rapidly growing global population requires crop systems capable of overcoming environmental stresses. Understanding the role of different signaling components in plant stress regulation is vital to developing crops which can withstand abiotic and biotic stresses without loss of crop yield and productivity. Emphasizing genomics and functional genomic approaches, Protein Kinases and Stress Signaling in Plants is a comprehensive review of cutting-edge research on stress perception, signal transduction, and stress response generation. Detailed chapters cover a broad range of topics central to improving agricultural production developing crop systems capable of overcoming environmental stresses to meet the needs of a rapidly growing global population. This book describes the field of protein kinases and stress signaling with a special emphasis on functional genomics. It presents a highly valuable contribution in the field of stress perception, signal transduction and generation of responses against one or multiple stress signals. This timely resource: Summarizes the role of various kinases involved in stress management Enumerates the role of TOR, GSK3-like kinase, SnRK kinases in different physiological conditions Examines mitogen-activated protein kinases (MAPKs) in different stresses Describes the different aspects of calcium signaling under different stress conditions Examines photo-activated kinases (PAPKs) in varying light conditions Briefs the presence of tyrosine kinases in plants Highlights the cellular functions of receptor ]like protein kinases (RLKs) Possible implication of these kinases in developing stress tolerant crops Protein Kinases and Stress Signaling in Plants: Functional Genomic Perspective is an essential resource for researchers and students in the fields of plant molecular biology and signal transduction, plant responses to stress, plant cell signaling, plant protein kinases, plant biotechnology, transgenic plants and stress biology.

Author : Rony Seger
Publisher : Springer Science & Business Media
Page : 335 pages
File Size : 41,8 Mb
Release : 2008-02-03
Category : Science
ISBN : 9781592596713

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MAP Kinase Signaling Protocols by Rony Seger Pdf

Mitogen-activated protein kinase (MAPK) signaling cascades are a group of protein kinases that play a central role in the intracellular transmission of extracellular signals. These cascades operate as major lines of communication within a complicated signaling network that regulates many cellular processes, including proliferation, differentiation, development, stress response, and apoptosis. More than 15,000 papers on MAPKs have been published over the past few years, with the number of publications increasing each year. More and more laboratories embark on the study of MAPK cascades in many d- tinct cellular systems and in particular their role in disease. Future challenges in the study of MAPK cascades remain in understa- ing the role of the various components and isoforms of the cascades in the multiple critical functions that they regulate in the whole organism, as well as the diseases caused by their malfunction. Data from gene-disrupted mice s- gest that inhibition of the MAPK cascades may have serious consequences on the development and growth of the animals. For example, targeted deletion of MEK1 is lethal, owing to developmental problems of placental vasculature and abnormal fibroblast migration. This lethality occurs in spite of the normal expression of MEK2, indicating that although the two MEK isoforms are apparently similar, they do have distinct functions, at least during embryog- esis. The ERK cascade was also shown to play a central role in brain function and in learning and memory.

Author : Ritva Tikkanen,David Nikolic-Paterson
Publisher : Unknown
Page : 276 pages
File Size : 47,9 Mb
Release : 2020
Category : Electronic
ISBN : 3039280716

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Mitogen Activated Protein Kinases by Ritva Tikkanen,David Nikolic-Paterson Pdf

Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.

Author : Anonim
Publisher : ScholarlyEditions
Page : 131 pages
File Size : 53,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464928635

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Proline-Directed Protein Kinases: Advances in Research and Application: 2011 Edition by Anonim Pdf

Proline-Directed Protein Kinases: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Proline-Directed Protein Kinases in a concise format. The editors have built Proline-Directed Protein Kinases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proline-Directed Protein Kinases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proline-Directed Protein Kinases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Nico Dissmeyer,Arp Schnittger
Publisher : Humana Press
Page : 0 pages
File Size : 47,9 Mb
Release : 2011-08-26
Category : Science
ISBN : 1617792632

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Plant Kinases by Nico Dissmeyer,Arp Schnittger Pdf

Modification of target protein properties by reversible phosphorylation events has been found to be one of the most prominent cellular control processes in all organisms. Recent advances in the areas of molecular biology and biochemistry are presenting new possibilities for reaching an unprecedented depth and a proteome-wide understanding of phosphorylation processes in plants as well as in other species. The major goal of Plant Kinases: Methods and Protocols is to provide the experimentalist with a detailed account of the practical steps necessary for successfully carrying out each protocol in his or her own laboratory. Plant protein kinases specifically addressed in this volume are members of the plant MAP kinase cascade, cyclin- and Calcium-dependent protein kinases, and plant sensor and receptor kinases. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Plant Kinases: Methods and Protocols will prove a useful laboratory companion to both novice and seasoned researchers by facilitating the practical work that will lead them to new and exciting insights in this dynamic field.

Author : Manfred Schwab
Publisher : Springer Science & Business Media
Page : 3307 pages
File Size : 49,7 Mb
Release : 2008-09-23
Category : Medical
ISBN : 9783540368472

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Encyclopedia of Cancer by Manfred Schwab Pdf

This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Author : Marc Thiriet
Publisher : Springer Science & Business Media
Page : 1073 pages
File Size : 49,7 Mb
Release : 2012-09-26
Category : Science
ISBN : 9781461443698

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Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems by Marc Thiriet Pdf

The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 55,5 Mb
Release : 19??
Category : Electronic
ISBN : 1461464382

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Encyclopedia of Signaling Molecules by Anonim Pdf