Mobility And Proximity In Biological Membranes

Mobility And Proximity In Biological Membranes Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Mobility And Proximity In Biological Membranes book. This book definitely worth reading, it is an incredibly well-written.

Mobility and Proximity in Biological Membranes

S. Damjanovich
Mobility and Proximity in Biological Membranes Book PDF

Author : S. Damjanovich
Publisher : CRC Press
Page : 347 pages
File Size : 52,8 Mb
Release : 2018-01-18
Category : Science
ISBN : 9781351083126

Get Book

Mobility and Proximity in Biological Membranes by S. Damjanovich Pdf

Cell surface membranes have long been characterized as two-dimensional fluids whose mobile components are randomized by diffusion in the plane of the membrane bilayer. Recent research has indicated that cell surface membranes are highly organized and ordered and that important functional units of membranes appear as arrays of interacting molecules rather than as single, freely diffusing molecules. Mobility and Proximity in Biological Membranes provides an overview of the results obtained from biophysical methods for probing the organization of cell surface membranes. These results are presented in the context of detailed treatments of the theory and the technical demands of each of the methods. The book describes a versatile and easily applied mode for investigating molecular proximities in plasma membranes in a flow cytometer. Its analysis of lipid fluidity and viscosity of membranes and the rotational mobility of proteins offers intimate insight into the physical chemistry of biological membranes. The electrophysiology of lymphocytes is presented with focus on its importance in different diseases. New techniques are described, and new data, new possibilities, and future trends are presented by world experts. This book's chapters can serve both as guides to the existing literature and as starting points for new experiments and approaches associated with problems in membrane function.

Membrane Permeability: 100 Years Since Ernest Overton

Anonim
Membrane Permeability 100 Years Since Ernest Overton Book PDF

Author : Anonim
Publisher : Academic Press
Page : 423 pages
File Size : 54,5 Mb
Release : 1999-05-21
Category : Science
ISBN : 0080585191

Get Book

Membrane Permeability: 100 Years Since Ernest Overton by Anonim Pdf

Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Provides an historical perspective of Overton's contributions to the theory of narcosis Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion

Membrane Protein-Cytoskeleton Interactions

Anonim
Membrane Protein Cytoskeleton Interactions Book PDF

Author : Anonim
Publisher : Academic Press
Page : 427 pages
File Size : 43,5 Mb
Release : 1996-11-21
Category : Science
ISBN : 0080585140

Get Book

Membrane Protein-Cytoskeleton Interactions by Anonim Pdf

The plasma membrane acts as both a boundary and a site of exchange between the outside and the inside of a cell. The cytoskeleton plays essential roles in delineating membrane protein distributions, in defining structural and functional domains in the plasma membrane, and in regulating membrane protein, and ultimately, cell function. This volume reviews the regulation of membrane protein distribution, organization, and function at the plasma membrane by the cytoskeleton. Discussions also include the roles of cytoskeleton in the structural and functional organization of membranes and membrane proteins with emphasis on key problems, the current status of understanding, experimental approaches, and future directions.

Modeling Differential Equations in Biology

Clifford Henry Taubes
Modeling Differential Equations in Biology Book PDF

Author : Clifford Henry Taubes
Publisher : Cambridge University Press
Page : 128 pages
File Size : 47,5 Mb
Release : 2008-01-17
Category : Mathematics
ISBN : 9781316582787

Get Book

Modeling Differential Equations in Biology by Clifford Henry Taubes Pdf

Based on a very successful one-semester course taught at Harvard, this text teaches students in the life sciences how to use differential equations to help their research. It needs only a semester's background in calculus. Ideas from linear algebra and partial differential equations that are most useful to the life sciences are introduced as needed, and in the context of life science applications, are drawn from real, published papers. It also teaches students how to recognize when differential equations can help focus research. A course taught with this book can replace the standard course in multivariable calculus that is more usually suited to engineers and physicists.

Membrane Organization and Dynamics

Amitabha Chattopadhyay
Membrane Organization and Dynamics Book PDF

Author : Amitabha Chattopadhyay
Publisher : Springer
Page : 387 pages
File Size : 40,7 Mb
Release : 2017-12-06
Category : Science
ISBN : 9783319666013

Get Book

Membrane Organization and Dynamics by Amitabha Chattopadhyay Pdf

This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes.

Biochemical Roles of Eukaryotic Cell Surface Macromolecules

Abhijit Chakrabarti,Avadhesha Surolia
Biochemical Roles of Eukaryotic Cell Surface Macromolecules Book PDF

Author : Abhijit Chakrabarti,Avadhesha Surolia
Publisher : Springer
Page : 411 pages
File Size : 52,7 Mb
Release : 2014-11-18
Category : Science
ISBN : 9783319112800

Get Book

Biochemical Roles of Eukaryotic Cell Surface Macromolecules by Abhijit Chakrabarti,Avadhesha Surolia Pdf

Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjugate metabolism · dysregulation · molecular mechanisms involved in cell-cell and cell-matrix interaction · glycans in infectious and neurological diseases · cancer and glycosyltransferases as drug targets.

Serotonin

Paul M. Pilowsky
Serotonin Book PDF

Author : Paul M. Pilowsky
Publisher : Academic Press
Page : 452 pages
File Size : 41,6 Mb
Release : 2018-09-21
Category : Medical
ISBN : 9780128005842

Get Book

Serotonin by Paul M. Pilowsky Pdf

Serotonin: The Mediator That Spans Evolution provides a comprehensive review of the widespread roles for serotonin in respiratory, cardiovascular and thermoregulatory control, and for growth and development in early life. This important resource highlights serotonin’s role in normal (unstressed) conditions, and in response to a variety of physiological stressors. It focuses on new animal models, comparing and contrasting data from mice and rats. In addition, the book compares and contrasts the physiological effects of brain and blood serotonin systems and includes new data suggesting that the influence of serotonin is in part through the regulation of gene expression. Finally, it discusses the role of serotonin system dysfunction in a variety of pathophysiological conditions, including sleep apnea, obesity and hypertension, and presents compelling evidence that this dysfunction is involved in Sudden Infant Death Syndrome (SIDS). Includes the latest information on new animal models of serotonin system dysfunction Explores the wide scope of serotonin’s influence on multiple organ and physiological systems Highlights the autonomous functioning of the brain and body serotonin systems Provides compelling evidence of serotonin dysfunction in SIDS, a leading cause of death in infancy

Fluorescent Proteins

Kevin F. Sullivan
Fluorescent Proteins Book PDF

Author : Kevin F. Sullivan
Publisher : Elsevier
Page : 613 pages
File Size : 52,9 Mb
Release : 2007-12-14
Category : Science
ISBN : 9780080557243

Get Book

Fluorescent Proteins by Kevin F. Sullivan Pdf

This new edition of Fluorescent Proteins presents current applications of autofluorescent proteins in cell and molecular biology authored by researchers from many of the key laboratories in the field. Starting from a current review of the broad palette of fluorescent proteins available, several chapters focus on key autofluorescent protein variants, including spectral variants, photodynamic variants as well as chimeric FP approaches. Molecular applications are addressed in chapters that detail work with single molecules, approaches to generating protein fusions and biosensors as well as analysis of protein-protein interactions in vivo by FRET, fluorescence polarization and fluorescence cross correlation techniques. A number of approaches to in vivo dynamics are presented, including FRAP, photoactivation, and 4-dimensional microscopy. Behavior of spindle components, membrane proteins, mRNA trafficking as well as analysis of cell types in tissues and in development are detailed and provide models for a wide variety of experimental approaches. In addition, several chapters deal directly with the computational issues involved in processing multidimensional image data and using fluorescent imaging to probe cellular behavior with quantitative modeling. This volume brings together the latest perspective and techniques on fluorescent proteins and will be an invaluable reference in a wide range of laboratories.

Methods in Membrane Lipids

Alex M. Dopico
Methods in Membrane Lipids Book PDF

Author : Alex M. Dopico
Publisher : Springer Science & Business Media
Page : 1265 pages
File Size : 47,6 Mb
Release : 2007-08-30
Category : Medical
ISBN : 9781588296627

Get Book

Methods in Membrane Lipids by Alex M. Dopico Pdf

This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the pros and cons as seen by the experts.

Prions and Brain Diseases in Animals and Humans

Douglas R.O. Morrison
Prions and Brain Diseases in Animals and Humans Book PDF

Author : Douglas R.O. Morrison
Publisher : Springer Science & Business Media
Page : 349 pages
File Size : 52,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781489918963

Get Book

Prions and Brain Diseases in Animals and Humans by Douglas R.O. Morrison Pdf

Most of the world's experts on prions met for a workshop in Erice in August 1996. The aim of the workshop was to discuss the fundamentals of the science ofprions. It was for tunate that so many could be present given the pressure that they were under because of the data presented in March 1996, indicating that Bovine Spongiform Encephalopathy, BSE or Mad Cow Disease, had penetrated the species barrier and was beginning to cause a new dis ease in humans--the new variant ofCreutzfeldt-Jakob Disease, nvCJD. This important and urgent subject became an additional major topic at the workshop. This is a book containing most of the talks plus the abstracts of those unable to find time to write up their talks. Almost all papers were written in the spring and summer of 1997 and contain material added after the workshop; thus Bob Will's paper on the new variant of cm contains data up to July 1997 and four contributions arrived in October 1997. In addition to the talks given at our workshop, there was a special joint session with the Planetary Emergencies Workshop where many distinguished scientists, including three Nobel laureates, discussed major issues affecting our planet. Six talks were given by us to this other workshop, five about prions, BSE, and nvCJD, and one on the broader issue of new epi demics by Luc Montagnier. Although most of the talks concerned research issues, there were a few special talks.

Fundamentals of Light Microscopy and Electronic Imaging

Douglas B. Murphy,Michael W. Davidson
Fundamentals of Light Microscopy and Electronic Imaging Book PDF

Author : Douglas B. Murphy,Michael W. Davidson
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 51,5 Mb
Release : 2012-08-22
Category : Medical
ISBN : 9781118382936

Get Book

Fundamentals of Light Microscopy and Electronic Imaging by Douglas B. Murphy,Michael W. Davidson Pdf

Fundamentals of Light Microscopy and Electronic Imaging, Second Edition provides a coherent introduction to the principles and applications of the integrated optical microscope system, covering both theoretical and practical considerations. It expands and updates discussions of multi-spectral imaging, intensified digital cameras, signal colocalization, and uses of objectives, and offers guidance in the selection of microscopes and electronic cameras, as well as appropriate auxiliary optical systems and fluorescent tags. The book is divided into three sections covering optical principles in diffraction and image formation, basic modes of light microscopy, and components of modern electronic imaging systems and image processing operations. Each chapter introduces relevant theory, followed by descriptions of instrument alignment and image interpretation. This revision includes new chapters on live cell imaging, measurement of protein dynamics, deconvolution microscopy, and interference microscopy. PowerPoint slides of the figures as well as other supplementary materials for instructors are available at a companion website: www.wiley.com/go/murphy/lightmicroscopy

Fluorescence Studies on Biological Membranes

Herwig J. Hilderson
Fluorescence Studies on Biological Membranes Book PDF

Author : Herwig J. Hilderson
Publisher : Springer Science & Business Media
Page : 480 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461393597

Get Book

Fluorescence Studies on Biological Membranes by Herwig J. Hilderson Pdf

As stated by its first editor, Dr. D. B. Roodyn, the primary goal of the series Subcellular Biochemistry is to achieve an integrated view of the cell by bringing together results from a wide range of different techniques and disciplines. This volume deals with the applications of fluorescence spectroscopy to membrane research. It seeks to present complementary biochemical and bio physical data on both the structure and the dynamics of biological membranes. Biophysics and biochemistry are improving more and more in their ability to study biomembranes, overlapping somewhat in this area and explaining the functioning of the whole cell in terms of the properties of its individual com ponents. Therefore, we have brought together an international group of experts in order to report on and review advances in fluorescence studies on biological membranes, thereby highlighting subcellular aspects. The first chapters present a critical evaluation of the current applications of dynamic and steady-state fluorescence techniques. Subsequent chapters dis cuss more specific applications in cells, biological membranes, and their con stituents (lipids, proteins).

Green Fluorescent Protein

Martin Chalfie,Steven R. Kain
Green Fluorescent Protein Book PDF

Author : Martin Chalfie,Steven R. Kain
Publisher : John Wiley & Sons
Page : 486 pages
File Size : 50,7 Mb
Release : 2005-11-18
Category : Science
ISBN : 9780471739487

Get Book

Green Fluorescent Protein by Martin Chalfie,Steven R. Kain Pdf

Since the discovery of the gene for green fluorescent protein (GFP), derived from jellyfish, this protein that emits a green glow has initiated a revolution in molecular biosciences. With this tool, it is now possible to visualize nearly any protein of interest in any cell or tissue of any species. Since the publication of the first edition, there have been tremendously significant technological advances, including development of new mutant variants. Proteins are now available in yellow and blue, and Novel Fluorescent Proteins (NFPs) have expanded their utility in developing biosensors, biological markers, and other biological applications. This updated, expanded new edition places emphasis on the rise of NFPs, including new chapters on NFP properties with detailed protocols, applications of GFPs and NFPs in industry research, and biosensors. This book provides a solid theoretical framework, along with detailed, practical guidance on use of GFPs and NFPs with discussion of potential pitfalls. The expert contributors provide real examples in showing how to tailor GFP/NFP to specific systems, maximize expression, and enhance detection.

Remediation Engineering of Contaminated Soils

Donald L. Wise
Remediation Engineering of Contaminated Soils Book PDF

Author : Donald L. Wise
Publisher : CRC Press
Page : 1011 pages
File Size : 53,9 Mb
Release : 2000-07-25
Category : Science
ISBN : 9781482289930

Get Book

Remediation Engineering of Contaminated Soils by Donald L. Wise Pdf

Offers thorough coverage of the remediation of soils contaminated by hazardous wastes, including materials, analytical techniques, cleanup design and methodology, characterization of geomedia, monitoring of contaminants in the subsurface, and waste containment. Cites specific case studies in hydrocarbon remediation that offer a concise overview of possible technological approaches.

Cell Imaging

David Stephens
Cell Imaging Book PDF

Author : David Stephens
Publisher : Scion Publishing Ltd
Page : 337 pages
File Size : 55,8 Mb
Release : 2005-12-01
Category : Science
ISBN : 9781907904387

Get Book

Cell Imaging by David Stephens Pdf

This book covers the key techniques that can be employed in any lab with access to cell imaging equipment, even if they do not currently specialize in imaging. It focuses on live cell imaging and light microscopy applications, but is equally relevant to the imaging of fixed specimens.