Modeling Brain Function

Author : D. J. Amit,Daniel J. Amit
Publisher : Cambridge University Press
Page : 528 pages
File Size : 44,9 Mb
Release : 1989
Category : Computers
ISBN : 0521421241

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Modeling Brain Function by D. J. Amit,Daniel J. Amit Pdf

One of the most exciting and potentially rewarding areas of scientific research is the study of the principles and mechanisms underlying brain function. It is also of great promise to future generations of computers. A growing group of researchers, adapting knowledge and techniques from a wide range of scientific disciplines, have made substantial progress understanding memory, the learning process, and self organization by studying the properties of models of neural networks - idealized systems containing very large numbers of connected neurons, whose interactions give rise to the special qualities of the brain. This book introduces and explains the techniques brought from physics to the study of neural networks and the insights they have stimulated. It is written at a level accessible to the wide range of researchers working on these problems - statistical physicists, biologists, computer scientists, computer technologists and cognitive psychologists. The author presents a coherent and clear nonmechanical presentation of all the basic ideas and results. More technical aspects are restricted, wherever possible, to special sections and appendices in each chapter. The book is suitable as a text for graduate courses in physics, electrical engineering, computer science and biology.

Author : Daniel J. Amit
Publisher : Unknown
Page : 504 pages
File Size : 54,7 Mb
Release : 1989
Category : Electronic
ISBN : OCLC:640566415

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Modeling Brain Function by Daniel J. Amit Pdf

Author : Daniel J. Amit
Publisher : Unknown
Page : 504 pages
File Size : 44,6 Mb
Release : 1992
Category : Electronic
ISBN : OCLC:848705818

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Modeling Brain Function by Daniel J. Amit Pdf

Author : Rajesh P.N. Rao,Bruno A. Olshausen,Michael S. Lewicki
Publisher : MIT Press
Page : 348 pages
File Size : 54,6 Mb
Release : 2002-03-29
Category : Medical
ISBN : 0262264323

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Probabilistic Models of the Brain by Rajesh P.N. Rao,Bruno A. Olshausen,Michael S. Lewicki Pdf

A survey of probabilistic approaches to modeling and understanding brain function. Neurophysiological, neuroanatomical, and brain imaging studies have helped to shed light on how the brain transforms raw sensory information into a form that is useful for goal-directed behavior. A fundamental question that is seldom addressed by these studies, however, is why the brain uses the types of representations it does and what evolutionary advantage, if any, these representations confer. It is difficult to address such questions directly via animal experiments. A promising alternative is to use probabilistic principles such as maximum likelihood and Bayesian inference to derive models of brain function. This book surveys some of the current probabilistic approaches to modeling and understanding brain function. Although most of the examples focus on vision, many of the models and techniques are applicable to other modalities as well. The book presents top-down computational models as well as bottom-up neurally motivated models of brain function. The topics covered include Bayesian and information-theoretic models of perception, probabilistic theories of neural coding and spike timing, computational models of lateral and cortico-cortical feedback connections, and the development of receptive field properties from natural signals.

Author : Stephen José Hanson,Carl R. Olson
Publisher : Bradford Book
Page : 448 pages
File Size : 43,9 Mb
Release : 1990
Category : Computers
ISBN : UOM:39015018506678

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Connectionist Modeling and Brain Function by Stephen José Hanson,Carl R. Olson Pdf

Bringing together contributions in biology, neuroscience, computer science, physics, and psychology, this book offers a solid tutorial on current research activity in connectionist-inspired biology-based modeling. It describes specific experimental approaches and also confronts general issues related to learning associative memory, and sensorimotor development. Introductory chapters by editors Hanson and Olson, along with Terrence Sejnowski, Christof Koch, and Patricia S. Churchland, provide an overview of computational neuroscience, establish the distinction between "realistic" brain models and "simplified" brain models, provide specific examples of each, and explain why each approach might be appropriate in a given context. The remaining chapters are organized so that material on the anatomy and physiology of a specific part of the brain precedes the presentation of modeling studies. The modeling itself ranges from simplified models to more realistic models and provides examples of constraints arising from known brain detail as well as choices modelers face when including or excluding such constraints. There are three sections, each focused on a key area where biology and models have converged. Stephen Jose Hanson is Member of Technical Staff, Bellcore, and Visiting Faculty, Cognitive Science Laboratory, Princeton University. Carl R. Olson is Assistant Professor, Department of Psychology at Princeton Connectionist Modeling and Brain Functionis included in the Network Modeling and Connectionism series, edited by Jeffrey Elman.

Author : Ronald MacGregor
Publisher : Elsevier
Page : 656 pages
File Size : 49,8 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323143844

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Neural and Brain Modeling by Ronald MacGregor Pdf

Neural and Brain Modeling reviews models used to study neural interactions. The book also discusses 54 computer programs that simulate the dynamics of neurons and neuronal networks to illustrate between unit and systemic levels of nervous system functions. The models of neural and brain operations are composed of three sections: models of generic mechanisms; models of specific neuronal systems; and models of generic operations, networks, and systems. The text discusses the computational problems related to galvanizing a neuronal population though an activity in the multifiber input system. The investigator can use a computer technique to simulate multiple interacting neuronal populations. For example, he can investigate the case of a single local region that contains two populations of neurons: namely, a parent population of excitatory cells, and a second set of inhibitory neurons. Computer simulation models predict the various dynamic activity occurring in the complicated structure and physiology of neuronal systems. Computer models can be used in "top-down" brain/mind research where the systemic, global, and emergent properties of nervous systems are generated. The book is recommended for behavioral scientists, psychiatrists, psychologists, computer programmers, students, and professors in human behavior.

Author : Chris Eliasmith
Publisher : Oxford University Press
Page : 475 pages
File Size : 46,6 Mb
Release : 2013-04-16
Category : Psychology
ISBN : 9780199794690

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How to Build a Brain by Chris Eliasmith Pdf

How to Build a Brain provides a detailed exploration of a new cognitive architecture - the Semantic Pointer Architecture - that takes biological detail seriously, while addressing cognitive phenomena. Topics ranging from semantics and syntax, to neural coding and spike-timing-dependent plasticity are integrated to develop the world's largest functional brain model.

Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Page : 195 pages
File Size : 49,5 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309045292

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Discovering the Brain by National Academy of Sciences,Institute of Medicine,Sandra Ackerman Pdf

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author : Ahmed A. Moustafa
Publisher : John Wiley & Sons
Page : 586 pages
File Size : 46,5 Mb
Release : 2017-11-13
Category : Psychology
ISBN : 9781119159063

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Computational Models of Brain and Behavior by Ahmed A. Moustafa Pdf

A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Author : Randolph W. Parks,Daniel S. Levine,Debra L. Long
Publisher : MIT Press
Page : 450 pages
File Size : 40,6 Mb
Release : 1998
Category : Cognition
ISBN : 0262161753

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Fundamentals of Neural Network Modeling by Randolph W. Parks,Daniel S. Levine,Debra L. Long Pdf

Provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. Over the past few years, computer modeling has become more prevalent in the clinical sciences as an alternative to traditional symbol-processing models. This book provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. It is intended to make the neural network approach accessible to practicing neuropsychologists, psychologists, neurologists, and psychiatrists. It will also be a useful resource for computer scientists, mathematicians, and interdisciplinary cognitive neuroscientists. The editors (in their introduction) and contributors explain the basic concepts behind modeling and avoid the use of high-level mathematics. The book is divided into four parts. Part I provides an extensive but basic overview of neural network modeling, including its history, present, and future trends. It also includes chapters on attention, memory, and primate studies. Part II discusses neural network models of behavioral states such as alcohol dependence, learned helplessness, depression, and waking and sleeping. Part III presents neural network models of neuropsychological tests such as the Wisconsin Card Sorting Task, the Tower of Hanoi, and the Stroop Test. Finally, part IV describes the application of neural network models to dementia: models of acetycholine and memory, verbal fluency, Parkinsons disease, and Alzheimer's disease. Contributors J. Wesson Ashford, Rajendra D. Badgaiyan, Jean P. Banquet, Yves Burnod, Nelson Butters, John Cardoso, Agnes S. Chan, Jean-Pierre Changeux, Kerry L. Coburn, Jonathan D. Cohen, Laurent Cohen, Jose L. Contreras-Vidal, Antonio R. Damasio, Hanna Damasio, Stanislas Dehaene, Martha J. Farah, Joaquin M. Fuster, Philippe Gaussier, Angelika Gissler, Dylan G. Harwood, Michael E. Hasselmo, J, Allan Hobson, Sam Leven, Daniel S. Levine, Debra L. Long, Roderick K. Mahurin, Raymond L. Ownby, Randolph W. Parks, Michael I. Posner, David P. Salmon, David Servan-Schreiber, Chantal E. Stern, Jeffrey P. Sutton, Lynette J. Tippett, Daniel Tranel, Bradley Wyble

Author : Mark Humphries
Publisher : Princeton University Press
Page : 232 pages
File Size : 48,9 Mb
Release : 2023-01-24
Category : Psychology
ISBN : 9780691241487

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The Spike by Mark Humphries Pdf

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.

Author : D. Alistair Steyn-Ross,Moira Steyn-Ross
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 48,9 Mb
Release : 2010-03-14
Category : Medical
ISBN : 9781441907967

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Modeling Phase Transitions in the Brain by D. Alistair Steyn-Ross,Moira Steyn-Ross Pdf

Foreword by Walter J. Freeman. The induction of unconsciousness using anesthetic agents demonstrates that the cerebral cortex can operate in two very different behavioral modes: alert and responsive vs. unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states. Modeling Phase Transitions in the Brain contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band Hopf oscillations, gap-junction-moderated Turing structures, and Hopf-Turing interactions leading to cortical waves.

Author : Karl J. Friston,Christopher D. Frith,Raymond J. Dolan,Cathy J. Price,Semir Zeki,John T. Ashburner,William D. Penny
Publisher : Elsevier
Page : 1144 pages
File Size : 51,6 Mb
Release : 2004-01-26
Category : Medical
ISBN : 0080472958

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Human Brain Function by Karl J. Friston,Christopher D. Frith,Raymond J. Dolan,Cathy J. Price,Semir Zeki,John T. Ashburner,William D. Penny Pdf

This updated second edition provides the state of the art perspective of the theory, practice and application of modern non-invasive imaging methods employed in exploring the structural and functional architecture of the normal and diseased human brain. Like the successful first edition, it is written by members of the Functional Imaging Laboratory - the Wellcome Trust funded London lab that has contributed much to the development of brain imaging methods and their application in the last decade. This book should excite and intrigue anyone interested in the new facts about the brain gained from neuroimaging and also those who wish to participate in this area of brain science. * Represents an almost entirely new book from 1st edition, covering the rapid advances in methods and in understanding of how human brains are organized * Reviews major advances in cognition, perception, emotion and action * Introduces novel experimental designs and analytical techniques made possible with fMRI, including event-related designs and non-linear analysis

Author : Sergey N. Makarov
Publisher : Springer Nature
Page : 395 pages
File Size : 49,6 Mb
Release : 2021
Category : Biomedical engineering
ISBN : 9783030456238

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Brain and Human Body Modeling 2020 by Sergey N. Makarov Pdf

The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.

Author : G. N. Reeke,R.R. Poznanski,K. A. Lindsay,J.R. Rosenberg,O. Sporns
Publisher : CRC Press
Page : 736 pages
File Size : 49,6 Mb
Release : 2005-03-29
Category : Science
ISBN : 0415328683

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Modeling in the Neurosciences by G. N. Reeke,R.R. Poznanski,K. A. Lindsay,J.R. Rosenberg,O. Sporns Pdf

Computational models of neural networks have proven insufficient to accurately model brain function, mainly as a result of simplifications that ignore the physical reality of neuronal structure in favor of mathematically tractable algorithms and rules. Even the more biologically based "integrate and fire" and "compartmental" styles of modeling suffer from oversimplification in the former case and excessive discretization in the second. This book introduces an integrative approach to modeling neurons and neuronal circuits that retains the integrity of the biological units at all hierarchical levels. With contributions from more than 40 renowned experts, Modeling in the Neurosciences, Second Edition is essential for those interested in constructing more structured and integrative models with greater biological insight. Focusing on new mathematical and computer models, techniques, and methods, this book represents a cohesive and comprehensive treatment of various aspects of the neurosciences from the molecular to the network level. Many state-of-the-art examples illustrate how mathematical and computer modeling can contribute to the understanding of mechanisms and systems in the neurosciences. Each chapter also includes suggestions of possible refinements for future modeling in this rapidly changing and expanding field. This book will benefit and inspire the advanced modeler, and will give the beginner sufficient confidence to model a wide selection of neuronal systems at the molecular, cellular, and network levels.