Modern Applications Of Cycloaddition Chemistry

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Modern Applications of Cycloaddition Chemistry

Author : Paolo Quadrelli
Publisher : Elsevier
Page : 352 pages
File Size : 47,9 Mb
Release : 2019-03-20
Category : Science
ISBN : 9780128152744

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Modern Applications of Cycloaddition Chemistry by Paolo Quadrelli Pdf

Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes Contains the most up-to-date review of the use of pericyclic reactions in drug delivery Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area

Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, Volume 59

Author : Albert Padwa,William H. Pearson
Publisher : John Wiley & Sons
Page : 962 pages
File Size : 42,5 Mb
Release : 2002-11-01
Category : Science
ISBN : 9780471280613

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Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, Volume 59 by Albert Padwa,William H. Pearson Pdf

Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.

The Chemistry of Heterocyclic Compounds, Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products

Author : Albert Padwa,William H. Pearson
Publisher : Wiley-Interscience
Page : 0 pages
File Size : 47,9 Mb
Release : 2002-04-19
Category : Science
ISBN : 0471387266

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The Chemistry of Heterocyclic Compounds, Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products by Albert Padwa,William H. Pearson Pdf

Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.

Cycloaddition Reactions in Organic Synthesis

Author : Shu Kobayashi,Karl Anker Jørgensen
Publisher : John Wiley & Sons
Page : 354 pages
File Size : 47,9 Mb
Release : 2002
Category : Science
ISBN : 3527301593

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Cycloaddition Reactions in Organic Synthesis by Shu Kobayashi,Karl Anker Jørgensen Pdf

During the miners' strike in the 1980s, a worker is killed in the striking coalfields of Wales. Some months later, a government minister thought to be connected with the death is also shot. Lewis Redfern—once a radical but now a political analyst and journalist—pursues the sniper, a lonely hunt that leads him through an imbroglio of civil service leaks to a secret organization: a source of insurrection far more powerful than anyone could have suspected known as the Volunteers. In this fast-paced narrative of espionage and intrigue, Redfern, through his obsessive pursuit of justice, finally encounters the truth about himself as the novel discusses the conflict between moral choice and political loyalty.

Methods and Applications of Cycloaddition Reactions in Organic Syntheses

Author : Nagatoshi Nishiwaki
Publisher : John Wiley & Sons
Page : 996 pages
File Size : 47,5 Mb
Release : 2013-12-17
Category : Science
ISBN : 9781118778203

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Methods and Applications of Cycloaddition Reactions in Organic Syntheses by Nagatoshi Nishiwaki Pdf

Advanced tools for developing new functional materials and applications in chemical research, pharmaceuticals, and materials science Cycloadditions are among the most useful tools for organic chemists, enabling them to build carbocyclic and heterocyclic structures. These structures can then be used to develop a broad range of functional materials, including pharmaceuticals, agrochemicals, dyes, and optics. With contributions from an international team of leading experts and pioneers in cycloaddition chemistry, this book brings together and reviews recent advances, trends, and emerging research in the field. Methods and Applications of Cycloaddition Reactions in Organic Syntheses focuses on two component cycloadditions, with chapters covering such topics as: N1 unit transfer reaction to C–C double bonds [3+2] Cycloaddition of α, β-unsaturated metal-carbene complexes Formal [3+3] cycloaddition approach to natural product synthesis Development of new methods for the construction of heterocycles based on cycloaddition reaction of 1,3-dipoles Cycloreversion approach for preparation of large π-conjugated compounds Transition metal-catalyzed or mediated [5+1] cycloadditions Readers will learn methods for seamlessly executing important reactions such as Diels-Alder and stereoselective dipolar reactions in order to fabricate heterocyclic compounds, natural products, and functional molecules. The book not only features cutting-edge topics, but also important background information, such as the contributors’ process for developing new methodologies, to help novices become fully adept in the field. References at the end of each chapter lead to original research papers and reviews for facilitating further investigation of individual topics. Covering the state of the science and technology, Methods and Applications of Cycloaddition Reactions in Organic Syntheses enables synthetic organic chemists to advance their research and develop new functional materials and applications in chemical research, pharmaceuticals, and materials science.

Advances in Cycloaddition

Author : Michael Harmata
Publisher : Elsevier
Page : 171 pages
File Size : 48,6 Mb
Release : 1999-03-18
Category : Science
ISBN : 0080546382

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Advances in Cycloaddition by Michael Harmata Pdf

The development and application of cycloaddition methodology continues to be at the forefront of research in synthetic organic chemistry. This volume begins with a review of methods available for the synthesis of seven-membered rings and is followed with work on metal-catalyzed cycloadditions. There is then an update on the cycloaddition chemistry of 2-pyrone, and then a unique application of photocycloaddition is detailed. The final chapter is a discussion of the latest explorations of the reaction of rhodium-stabilized vinyl carbenoids with dienes.

Advances in Heterocyclic Chemistry

Author : Eric F.V. Scriven,Christopher A. Ramsden
Publisher : Academic Press
Page : 332 pages
File Size : 43,6 Mb
Release : 2022-02-15
Category : Science
ISBN : 9780323901284

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Advances in Heterocyclic Chemistry by Eric F.V. Scriven,Christopher A. Ramsden Pdf

Advances in Heterocyclic Chemistry, Volume 136 is the latest release in this definitive series in the field of heterocyclic chemistry, one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Current Topics in Chirality

Author : Takashiro Akitsu
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 47,8 Mb
Release : 2021-09-01
Category : Science
ISBN : 9781839689536

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Current Topics in Chirality by Takashiro Akitsu Pdf

Chirality is a concept related not only to organic chemistry but also to each field of natural science. Awareness of hierarchy is important for universal and comprehensive understanding. As such, this book examines myriad subjects related to chirality in chemistry and interdisciplinary applications. In contrast to the previous book, this new book about chirality includes contributions from authors in many fields of natural science, providing a wider overview. The book’s focus is chirality and organic chemistry, including synthesis and reactions.

Alkynes in Cycloadditions

Author : Irina A. Maretina
Publisher : John Wiley & Sons
Page : 357 pages
File Size : 40,5 Mb
Release : 2013-10-08
Category : Science
ISBN : 9781118709290

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Alkynes in Cycloadditions by Irina A. Maretina Pdf

Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.

Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery

Author : Singh, Ajeet
Publisher : IGI Global
Page : 754 pages
File Size : 45,8 Mb
Release : 2022-06-24
Category : Science
ISBN : 9781668451304

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Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery by Singh, Ajeet Pdf

A great deal of interest has been generated recently in the isolation, characterization, and biological activity of phytochemicals. Phytochemicals have the potential to enhance pharmaceuticals and drug discovery. As such, there is an urgent need for current research in the global scope of phytochemicals including the chemical and physical characteristics, analytical procedures, biological activity, safety, and industrial applications. The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it presents a novel dietary approach for human disease management. Covering topics such as computer-aided drug design, government regulation, and medicinal plant taxonomy, this major reference work is beneficial to pharmacists, medical practitioners, phytologists, hospital administrators, government officials, faculty and students of higher education, librarians, researchers, and academicians.

Modern Acetylene Chemistry

Author : Peter J. Stang,François Diederich
Publisher : John Wiley & Sons
Page : 527 pages
File Size : 40,5 Mb
Release : 2008-09-26
Category : Science
ISBN : 9783527615261

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Modern Acetylene Chemistry by Peter J. Stang,François Diederich Pdf

This comprehensive handbook presents the full potential of modern acetylene chemistry, from organic synthesis through materials science to bioorganic chemistry. K. Houk, H. Hopf, P. Stang, K. M. Nicholas, N. Schore, M. Regitz, K. C. Nicolaou, R. Gleiter, L. Scott, R. Grubbs, H. Iwamura, J. Moore, and F. Diederich - internationally renowned authors introduce the reader, in a didactically skilful manner, to the state-of-the-art in alkyne chemistry. Emphasis is placed on presenting carefully selected and instructive examples as well as essential references to the original literature. Special benefits: Each chapter is rounded off by useful experimental procedures.

Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, Volume 59

Author : Albert Padwa,William H. Pearson
Publisher : John Wiley & Sons
Page : 952 pages
File Size : 44,6 Mb
Release : 2003-04-14
Category : Science
ISBN : 9780471461364

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Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, Volume 59 by Albert Padwa,William H. Pearson Pdf

Dipolar cycloaddition reactions have found many useful applications in chemistry, particularly with respect to the synthesis of compounds with new chiral centers. Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products updates the popular 1984 edition, featuring the advances made over the past twenty years and focusing on synthetic applications.

1,4-Cycloaddition Reaction: The Diels-Alder Reaction in Heterocyclic Syntheses

Author : Jan Hamer
Publisher : Elsevier
Page : 513 pages
File Size : 52,8 Mb
Release : 2013-07-19
Category : Science
ISBN : 9780323163118

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1,4-Cycloaddition Reaction: The Diels-Alder Reaction in Heterocyclic Syntheses by Jan Hamer Pdf

Organic Chemistry, Volume 8: 1,4-Cycloaddition Reactions: The Diels-Alder Reaction in Heterocyclic Syntheses describes 1,4-cycloaddition reactions leading to the formation of five- or six-membered heterocyclic compounds. Divided into 13 chapters, this book starts with an overview of various 1,4-cycloaddition reaction equations in the presence of at least one atom other than carbon. The following chapters describe the reaction mechanisms of five- or six-membered ring formed upon reaction with a dienophile, which contains an atom other than carbon. Considerable chapters are devoted to compounds used as dienophiles, including trivalent phosphorus, cyanogens and cyanogens-like compounds, imino, azo, carbonyl, thiocarbonyl, and diene compounds, as well as oxygen. Other chapters highlight some 1,4-cycloaddition reactions taking place through free radical intermediates. This book is of value to organic and research chemists, as well as undergraduate and graduate organic chemistry students.

Cycloaddition Reactions in Organic Synthesis

Author : W. Carruthers
Publisher : Elsevier Science & Technology
Page : 388 pages
File Size : 47,8 Mb
Release : 1990
Category : Organic compounds
ISBN : UOM:39076001677439

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Cycloaddition Reactions in Organic Synthesis by W. Carruthers Pdf

Paperback. Demonstrates the wide scope of cycloaddition reactions, including the Diels-Alder reaction, the ene reaction, 1,3-dipolar cycloadditions and [2]2] cycloadditions in organic synthesis. The author, a leading exponent of the subject, illustrates the ways in which they can be employed in the synthesis of a wide range of carbocyclic and heterocyclic compounds, including a variety of natural products of various types. Special attention is given to intramolecular reactions, which often provide a rapid and efficient route to polycyclic compounds, and to the stereochemistry of the reactions, including recent and developing work on enantioselective synthesis.

Modern Aryne Chemistry

Author : Akkattu T. Biju
Publisher : John Wiley & Sons
Page : 530 pages
File Size : 43,8 Mb
Release : 2021-08-23
Category : Science
ISBN : 9783527346462

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Modern Aryne Chemistry by Akkattu T. Biju Pdf

A groundbreaking book to offer a a comprehensive account of important reactions involving arynes Modern Aryne Chemistry is the first book on the market to offer a conceptual framework to the reactions related to arynes. It also provides a systematic introduction to the cycloaddition reactions, insertion reactions and transition-metal-catalyzed transformations of arynes. The author, a noted expert on the topic, highlights a novel strategy for carbon-carbon and carbon-heteroatom bond construction using arynes. The book reveiws the recent use of aryne chemistry for the development of new multicomponent reactions. New advances in this area has shown rapid emergence of a new class of reactions classified under rearrangement reactions. The author also includes information on aryne methods that have been employed for the synthesis of several natural products. The simplicity and sophistication of the synthetic strategy using arynes can serve as a springboard for organic chemists to explore new possibilities and imagine applications of the concept of arynes. This important book: Presents a one-of-kind comprehensive guide to arynes reactions Offers a proven approach to the synthesis of natural product and polymers Reviews the most recent developments in the carbon-carbon and carbon-heteroatom bond-forming reactions involving arynes Written for organic, pharmaceutical, medicinal, natural products, and catalytic Chemists, Modern Aryne Chemistry offers a comprehensive review of the fundamentals of reactions related to arynes and the most recent developments in the field.