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Author : Maynard B. Chenoweth
Publisher : Springer Science & Business Media
Page : 607 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642650550
With contributions by numerous experts
Author : Jürgen Schüttler,Helmut Schwilden
Publisher : Springer Science & Business Media
Page : 498 pages
File Size : 47,9 Mb
Release : 2008-01-08
Category : Medical
ISBN : 9783540748069
Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”.
Author : Maynard B. Chenoweth,Paul Bass
Publisher : Springer
Page : 591 pages
File Size : 42,6 Mb
Release : 1972
Category : Anesthetics
ISBN : 038705135X
Author : Kurt A. Grimm,Leigh A. Lamont,William J. Tranquilli,Stephen A. Greene,Sheilah A. Robertson
Publisher : John Wiley & Sons
Page : 1072 pages
File Size : 51,6 Mb
Release : 2015-05-11
Category : Medical
ISBN : 9781118526231
Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images
Author : Franz Jesch,K. Peter
Publisher : Springer
Page : 259 pages
File Size : 50,6 Mb
Release : 2013-12-14
Category : Medical
ISBN : 9783662399446
In clinical anaesthesiology the inhalation anaesthetics halothane (fluothane), enflurane and - in recent times - forane got a renaissance in clinical application. The reasons are not only the ad vantages of volatile anaesthetics, but also the fact that the investi gations of pharmacodynamics and pharmacokinetics of Lv. narcot ics showed negative aspects. It was the aim of the organizers of the symposium to give a survey of the present state of knowledge on inhalation anaesthetics, which is as up-to-date, critical as well as detailed as possible. Furthermore it was the intention to evaluate the recent advances made in the field of basic research. The first section of the symposium in particular enters into the question of the toxicity of volatile anaesthetics as well as their mechanisms of action. In a second main part the influences on cardiovascular system and on microcirculation are discussed. Apart from the extensive discussion of the advances in knowledge in the field of cardiovascular pathophysiology, the focal point of the contribut ions is made up of those with anaesthesia in coronary heart disease and cardiac insufficieny as well as the contribution on interactions of inhalation anaesthetics with cardiovascular drugs. In the third and fourth section the influences of volatile anaesthetics on cerebral, hepatic, renal and pulmonary function are dealt with as well as questions concerning the clinical application. Particular attention is given to the important problems of indicat ion in patients belonging to the extreme age groups.
Author : Angelo Raffaele De Gaudio,Stefano Romagnoli
Publisher : Springer
Page : 263 pages
File Size : 43,5 Mb
Release : 2018-01-23
Category : Medical
ISBN : 9783319593128
This book provides a comprehensive guide to delivering analgesia and sedation to critically ill patients for professionals and caregivers being involved in the management of these patients. It discusses and explains in detail the advantages and limitations of each drug and device using clear flowcharts, diagrams and tables. Furthermore, it explores the new drugs and – above all – new sedation delivery systems, particularly those for administering volatile anesthetics on ICUs. This book is a valuable and practical resource for anesthesists, intensivists and emergency physicians interested in sedation.
Author : Klaus Peter,Burnell R. Brown,Eike Martin,Olof Norlander
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642712326
In 1981, the Institute of Anesthesiology at the Ludwig Maximil ian University of Munich organized a first international sympo sium on inhalation anesthetics. In 1982, the most important con tributions were published in the series Anaesthesiology and Inten sive Care Medicine. At that time, the interest of European anes thesiologists was focused on isoflurane, which had just been in troduced for clinical purposes. Studies on this product had al ready been appearing for years in the American literature. This book deals once more with all three inhalation anesthetics, but places particular emphasis on isoflurane. In contrast to the situa tion in 1981, extensive experimental and clinical investigations on isoflurane have by now become available in the European litera ture. From its conception, the objective of this symposium was not to discuss the relative value of inhalation anesthesia (bal anced anesthesia) as compared with intravenous anesthesia. On the contrary, the major effects and interactions of isoflurane were to be explored. The side effects and their relative significance in different patient groups were also of interest. eurrent knowledge concerning a range of topics related to inhalation anesthetics (es pecially isoflurane) was to be presented in a comprehensive and critical manner. The effects of isoflurane on the cardiovascular system were the focus of interest during the symposium and are accordingly dealt with extensively in this volume. The comparative effects on cor onary perfusion of isoflurane, enflurane, and halothane are de scribed in detail.
Author : Darius Rastegar,Michael I. Fingerhood
Publisher : Oxford University Press, USA
Page : 465 pages
File Size : 55,8 Mb
Release : 2020
Category : Medical
ISBN : 9780197506172
The book is a practical guide to caring for individuals with substance use disorder. Written for generalists and non-addiction specialists, this new edition emphasizes compassionate, non-stigmatizing, patient-focused care.
Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Page : 128 pages
File Size : 51,6 Mb
Release : 2011-03-10
Category : Medical
ISBN : 9781139497022
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Author : Jan Baum
Publisher : Butterworth-Heinemann
Page : 338 pages
File Size : 47,7 Mb
Release : 2001
Category : Anesthesia
ISBN : UOM:39015049710406
Low flow anaesthesia is a technique of anaesthetic management which uses reduced fresh gas flow administered and controlled via a rebreathing system. The first edition of Low Flow Anaesthesia set out to reassure and educate anaesthetists in the theory and practicalities of low flow, minimal flow and closed system anaesthesia.
Author : Charles Vacanti,Scott Segal,Pankaj Sikka,Richard Urman
Publisher : Cambridge University Press
Page : 1191 pages
File Size : 45,5 Mb
Release : 2011-07-11
Category : Medical
ISBN : 9781139498401
The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.
Author : T.H. Stanley,Talmage D. Egan
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401145664
Anesthesia for the New Millenium: Modern Anesthetic Clinical Pharmacology contains the refresher course lectures of the 1999 meeting and is a review of the current state of the art in anesthesia clinical pharmacology. The authors of the individual chapters are among the world's most widely recognized experts in the pharmacology of perioperative medicine. The book features sections on new pharmacology concepts, new drug delivery techniques, recently released drugs and novel thinking about older drugs. It also addresses several areas that have recently emerged as very hot clinical and research topics, including depth of anesthesia monitoring technology and anesthesia drug interactions. The textbook is the seventeenth in a continuing series documenting the proceedings of the postgraduate course.
Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 44,5 Mb
Release : 1999
Category : Medical
ISBN : 0781719526
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author : Ruben Vardanyan,Victor Hruby
Publisher : Elsevier
Page : 634 pages
File Size : 49,9 Mb
Release : 2006-03-10
Category : Medical
ISBN : 008046212X
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references
Author : Alan David Kaye,Adam M. Kaye,Richard D. Urman
Publisher : Springer
Page : 904 pages
File Size : 52,8 Mb
Release : 2014-11-20
Category : Medical
ISBN : 9781461489481
In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) “black box” warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians.