Modern Management Of High Grade Glioma

Author : Isaac Yang,Seunggu J. Han
Publisher : Elsevier Health Sciences
Page : 174 pages
File Size : 55,5 Mb
Release : 2012-04-28
Category : Medical
ISBN : 9781455744183

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Modern Management of High Grade Glioma, Part I, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Author : Isaac Yang,Seunggu J. Han
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 51,8 Mb
Release : 2012-07-15
Category : Medical
ISBN : 9781455747689

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Modern Management of High Grade Glioma, Part II, An Issue of Neurosurgery Clinics - E-Book by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.

Author : Anonim
Publisher : Saunders
Page : 0 pages
File Size : 53,7 Mb
Release : 2012
Category : Gliomas
ISBN : OCLC:1075872625

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Modern Management of High Grade Glioma by Anonim Pdf

Author : Isaac Yang,Seunggu J. Han
Publisher : Saunders
Page : 0 pages
File Size : 48,6 Mb
Release : 2012-04
Category : Medical
ISBN : 1455738972

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Modern Management of High Grade Glioma, Part I, an Issue of Neurosurgery Clinics by Isaac Yang,Seunggu J. Han Pdf

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts to highlight the latest updates on various forms of management of high grade glioma. Some of the articles included in this issue focus on Extent of Resection for Glioblastoma; Role of adjuvant radiation therapy; Survival benefit of the Temozolomide protocol; Alternative chemotherapeutic agents; The role of avastin; Radiology; Pseuodprogression and Treatment effect; Pathology; Medical Management; Management of insular gliomas; Use of motor mapping; GBM treatment with clinical trials for surgical resection; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Future role of CED for GBM treatment; Application of a vault nanoparticle therapy for GBM therapy; Management of high grade gliomas in pediatric populations; Targeting Glioma Stem Like Cells with a focus on CD 133; and Potential Role for STAT3 inhibitors in glioblastoma.

Author : Michael E. Sughrue,Isaac Yang
Publisher : Academic Press
Page : 256 pages
File Size : 40,9 Mb
Release : 2019-08-03
Category : Medical
ISBN : 9780128136348

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New Techniques for Management of ‘Inoperable’ Gliomas by Michael E. Sughrue,Isaac Yang Pdf

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

Author : Gene H. Barnett
Publisher : Springer Science & Business Media
Page : 493 pages
File Size : 48,7 Mb
Release : 2007-11-21
Category : Medical
ISBN : 9781597451857

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High-Grade Gliomas by Gene H. Barnett Pdf

This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response. The first such “breakthrough” in high-grade glioma was the observation that loss of chromosomes 1p and 19q uniformly predict chemosensitivity in anaplastic oligodendrogliomas (1).

Author : Manmeet Ahluwalia,Philippe Metellus,Riccardo Soffietti
Publisher : Springer Nature
Page : 421 pages
File Size : 52,9 Mb
Release : 2019-11-05
Category : Medical
ISBN : 9783030234171

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Central Nervous System Metastases by Manmeet Ahluwalia,Philippe Metellus,Riccardo Soffietti Pdf

This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Author : Ruijiang Li,Lei Xing,Sandy Napel,Daniel L. Rubin
Publisher : CRC Press
Page : 420 pages
File Size : 49,6 Mb
Release : 2019-07-09
Category : Science
ISBN : 9781351208260

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Radiomics and Radiogenomics by Ruijiang Li,Lei Xing,Sandy Napel,Daniel L. Rubin Pdf

Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation

Author : Frederik Wenz
Publisher : Springer
Page : 0 pages
File Size : 50,9 Mb
Release : 2023-08-29
Category : Medical
ISBN : 3319684701

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Radiation Oncology by Frederik Wenz Pdf

In this Handbook, a team of leading experts provide a comprehensive and up-to-date overview of the ever-changing field of radiation oncology. The publication is divided into three volumes, the first of which covers basics such as radiotherapy techniques, treatment documentation, clinical radiobiology, and patient management. In the second volume, all aspects of clinical radiation therapy are discussed in depth for the full range of tumor types. In order to ensure that the reader has a full understanding of cancer management in each scenario, information is also provided on diagnosis and classification, general management principles, the role of surgical and systemic therapy, and prognosis. The third volume focuses on medical physics, covering the mathematical and computer science background, biophysics, radiation physics, instrumentation, tracer kinetic modeling, pharmacokinetics and pharmacodynamics, radiation sources and detectors, biomedical engineering, imaging techniques, radiation treatment planning, and quality assurance. This book will be invaluable for all radiation oncologists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
Publisher : Karger Medical and Scientific Publishers
Page : 252 pages
File Size : 51,5 Mb
Release : 2017-12-14
Category : Medical
ISBN : 9783318060577

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Intracranial Gliomas Part I - Surgery by M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon Pdf

Aggressive surgical removal is generally considered the main initial management option for most intracranial gliomas. It often results in resolution or alleviation of neurological symptoms and signs, normalizes intracranial pressure, facilitates characterization of the neoplasm, creates optimal conditions for adjuvant therapy and neurorehabilitation, and leads to prolongation of progression-free and overall survival of patients. Leading experts in neurosurgical oncology have contributed to this volume, highlighting modern principles of surgery for both newly-diagnosed and recurrent intracranial gliomas in adult as well as pediatric patients. The first of a three-volume set, it details epidemiological aspects, defines the importance of preoperative imaging, and describes current perioperative adjuvant needs. In addition, contemporary methods of intraoperative neurophysiological monitoring, the value of brain mapping for functional preservation, tips to prevent complications, and postoperative results are presented and discussed. This book and its accompanying volumes are mainly directed at neurosurgeons, neuro-oncologists and other clinicians treating patients with brain tumors.

Author : Erasmo Barros Da Silva Junior,Jerônimo Buzetti Milano
Publisher : BoD – Books on Demand
Page : 142 pages
File Size : 49,7 Mb
Release : 2019-03-13
Category : Medical
ISBN : 9781789854053

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Primary Intracranial Tumors by Erasmo Barros Da Silva Junior,Jerônimo Buzetti Milano Pdf

This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.

Author : Allan H. Friedman
Publisher : Cambridge University Press
Page : 237 pages
File Size : 52,8 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107065970

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The Duke Glioma Handbook by Allan H. Friedman Pdf

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Author : Amit Agrawal
Publisher : BoD – Books on Demand
Page : 214 pages
File Size : 51,5 Mb
Release : 2022-04-20
Category : Medical
ISBN : 9781839698033

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Brain Tumors by Amit Agrawal Pdf

Brain tumors comprise a spectrum of histological patterns. Their presentation and management depend on their location, size, and grade of lesions. This book is a collection of high-quality research work from global experts on brain tumors, including meningiomas, and their treatment.

Author : Christina A. Meyers,James R. Perry
Publisher : Cambridge University Press
Page : 0 pages
File Size : 45,6 Mb
Release : 2012-12-13
Category : Medical
ISBN : 1107411815

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Cognition and Cancer by Christina A. Meyers,James R. Perry Pdf

This book is a unique resource on the influence cancer and cancer treatments have on cognition. The majority of cancer patients on active treatment experience cognitive impairments often referred to as 'chemobrain' or 'chemofog'. In addition, patients with primary or metastatic tumors of the brain often experience direct neurologic symptoms. This book helps health care professionals working with cancer patients who experience cognitive changes and provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; and intervention strategies for affected patients. In short, it will explain how to identify, assess and treat these conditions.

Author : Carsten Nieder,Johannes Langendijk
Publisher : Springer
Page : 364 pages
File Size : 46,7 Mb
Release : 2016-10-25
Category : Medical
ISBN : 9783319418254

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Re-Irradiation: New Frontiers by Carsten Nieder,Johannes Langendijk Pdf

This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.