New Techniques For Management Of Inoperable Gliomas

Author : Michael E. Sughrue,Isaac Yang
Publisher : Academic Press
Page : 256 pages
File Size : 49,8 Mb
Release : 2019-08-03
Category : Medical
ISBN : 9780128136348

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New Techniques for Management of ‘Inoperable’ Gliomas by Michael E. Sughrue,Isaac Yang Pdf

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

Author : Michael E. Sughrue
Publisher : Thieme
Page : 827 pages
File Size : 41,9 Mb
Release : 2019-10-25
Category : Medical
ISBN : 9781626234451

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The Glioma Book by Michael E. Sughrue Pdf

A unique resource on glioma leverages advances and firsthand insights to enact meaningful change Glioblastoma (GBM) or glioma is an extremely aggressive and malignant brain tumor, with cell infiltration, rapid invasion, and a high frequency of relapse. The Glioma Book by neurosurgeon Michael Sughrue is a highly personal book — a culmination of two years of writing and more than 1,000 surgeries. It presents a unique viewpoint with the potential to transform the traditional paradigm that too often informs treatment of this universally fatal brain tumor. The book reinterprets the role of the cerebrum and sub-cortex, leverages scientific advances to improve cytoreduction and reduce neurological deficits, and challenges the myth of the "inoperable" glioma. This is the first step-by-step technical guide focused on aggressively resecting different types of gliomas. The book is logically organized, starting with a foundation of fundamental knowledge, then progressing to practical applications. Chapters focus on the skills necessary to perform glioma surgery, specific techniques, and systematic approaches to gliomas in different brain regions. Numerous case examples illuminate concepts introduced earlier in the book and explain how to perform these procedures About 30 high quality videos posted online provide insightful procedural guidance The role of connectomic imaging in visualizing the cerebrum, and other innovative techniques including awake brain mapping and diffusion tensor tractography Neurosurgeons who embrace the concepts in this book will realize they can change the glioma treatment paradigm. Continually improving techniques and viewing a glioma diagnosis as a battle for a patient's life, rather than an exercise in inevitable failure can impart progress in treating this devastating disease.

Author : Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam
Publisher : Academic Press
Page : 554 pages
File Size : 55,7 Mb
Release : 2021-04-09
Category : Medical
ISBN : 9780128217559

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Epidemiology of Brain and Spinal Tumors by Jahangir Moini,Nicholas Avgeropoulos,Mohtashem Samsam Pdf

Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment

Author : Carsten Nieder,Johannes Langendijk
Publisher : Springer
Page : 364 pages
File Size : 50,8 Mb
Release : 2016-10-25
Category : Medical
ISBN : 9783319418254

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Re-Irradiation: New Frontiers by Carsten Nieder,Johannes Langendijk Pdf

This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.

Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
Publisher : Karger Medical and Scientific Publishers
Page : 252 pages
File Size : 48,7 Mb
Release : 2017-12-14
Category : Medical
ISBN : 9783318060577

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Intracranial Gliomas Part I - Surgery by M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon Pdf

Aggressive surgical removal is generally considered the main initial management option for most intracranial gliomas. It often results in resolution or alleviation of neurological symptoms and signs, normalizes intracranial pressure, facilitates characterization of the neoplasm, creates optimal conditions for adjuvant therapy and neurorehabilitation, and leads to prolongation of progression-free and overall survival of patients. Leading experts in neurosurgical oncology have contributed to this volume, highlighting modern principles of surgery for both newly-diagnosed and recurrent intracranial gliomas in adult as well as pediatric patients. The first of a three-volume set, it details epidemiological aspects, defines the importance of preoperative imaging, and describes current perioperative adjuvant needs. In addition, contemporary methods of intraoperative neurophysiological monitoring, the value of brain mapping for functional preservation, tips to prevent complications, and postoperative results are presented and discussed. This book and its accompanying volumes are mainly directed at neurosurgeons, neuro-oncologists and other clinicians treating patients with brain tumors.

Author : Peter C. Burger,Bernd W. Scheithauer
Publisher : American Registry of Pathology
Page : 470 pages
File Size : 43,6 Mb
Release : 1994
Category : Medical
ISBN : UOM:39015037693747

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Tumors of the Central Nervous System by Peter C. Burger,Bernd W. Scheithauer Pdf

Author : Allan H. Friedman
Publisher : Cambridge University Press
Page : 237 pages
File Size : 53,6 Mb
Release : 2016-03-31
Category : Medical
ISBN : 9781107065970

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The Duke Glioma Handbook by Allan H. Friedman Pdf

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Author : Aasa Feragen,Stefan Sommer,Julia Schnabel,Mads Nielsen
Publisher : Springer Nature
Page : 784 pages
File Size : 53,7 Mb
Release : 2021-06-20
Category : Computers
ISBN : 9783030781910

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Information Processing in Medical Imaging by Aasa Feragen,Stefan Sommer,Julia Schnabel,Mads Nielsen Pdf

This book constitutes the proceedings of the 27th International Conference on Information Processing in Medical Imaging, IPMI 2021, which was held online during June 28-30, 2021. The conference was originally planned to take place in Bornholm, Denmark, but changed to a virtual format due to the COVID-19 pandemic. The 59 full papers presented in this volume were carefully reviewed and selected from 200 submissions. They were organized in topical sections as follows: registration; causal models and interpretability; generative modelling; shape; brain connectivity; representation learning; segmentation; sequential modelling; learning with few or low quality labels; uncertainty quantification and generative modelling; and deep learning.

Author : Ibrahim Omerhodzic,Kenan Arnautovic
Publisher : BoD – Books on Demand
Page : 260 pages
File Size : 54,5 Mb
Release : 2019-01-16
Category : Medical
ISBN : 9781789849530

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Glioma by Ibrahim Omerhodzic,Kenan Arnautovic Pdf

The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Author : Jeffrey Raizer,Andrew Parsa
Publisher : Springer
Page : 184 pages
File Size : 55,9 Mb
Release : 2014-12-02
Category : Medical
ISBN : 9783319120485

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Current Understanding and Treatment of Gliomas by Jeffrey Raizer,Andrew Parsa Pdf

This book reviews the significant advances in our understanding of glioma biology that have been achieved during the past decade and describes in detail the resultant new approaches to treatment. Improvements in surgical techniques, radiation therapy, and chemotherapy are comprehensively covered, with discussion of their impact in decreasing patient morbidity and increasing survival. In addition, individual chapters are devoted specifically to current treatment for low-grade gliomas, anaplastic gliomas, and glioblastoma multiforme. Other topics addressed include treatment of the elderly patient, investigating emerging therapies from small molecules to immunotherapy and palliative care. This timely book will be a valuable source of up-to-date information for practitioners and will also be of interest to researchers.

Author : Katrin Scheinemann,Eric Bouffet
Publisher : Springer
Page : 0 pages
File Size : 52,6 Mb
Release : 2024-08-27
Category : Medical
ISBN : 303162016X

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Pediatric Neuro-oncology by Katrin Scheinemann,Eric Bouffet Pdf

While the first edition of this book provided a succinct introduction to pediatric neuro-oncology, biological knowledge of childhood CNS tumors has “exploded” over the past few years and a new edition of this textbook is needed to keep it up-to-date. This updated edition will include chapters on cancer predisposition in children with brain tumors, gliomas, embryonal brain tumors, ependymoma, CNS-GCT, targeted therapies in pediatric brain tumors, and long-term sequelae. New developments covered include the following: - Techniques like DNA methylation have improved the diagnostic process, and have led to an integrated diagnosis of histology, ICH and methylation. - Tumor pathways have been detected, which defines more subgroups within a tumor entity, and results in more individualized treatment for the patient. - Therapeutic options outside the standard combination of surgery, chemotherapy, and radiation have either been implemented within the last years, or are currently under consideration. This book will be aimed at pediatric oncologists and neurooncologists, neurosurgeons, radiation oncologists. Chapters detailing quality of life and supportive care will make this 2nd edition a useful resource for nurses, social workers, physiotherapists, and occupational therapists alike.

Author : Gareth W. Roberts,Julia M. Polak
Publisher : Cambridge University Press
Page : 204 pages
File Size : 51,5 Mb
Release : 1995-06-08
Category : Medical
ISBN : 0521425581

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Molecular Neuropathology by Gareth W. Roberts,Julia M. Polak Pdf

This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.

Author : P. Nicolai,P.J. Bradley
Publisher : Karger Medical and Scientific Publishers
Page : 266 pages
File Size : 41,7 Mb
Release : 2020-07-30
Category : Medical
ISBN : 9783318066708

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Anterior Skull Base Tumors by P. Nicolai,P.J. Bradley Pdf

In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.

Author : Kaisorn Chaichana,Alfredo Quinones-Hinojosa
Publisher : Academic Press
Page : 506 pages
File Size : 44,8 Mb
Release : 2019-02-28
Category : Medical
ISBN : 9780128117842

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Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors by Kaisorn Chaichana,Alfredo Quinones-Hinojosa Pdf

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them. Provides a comprehensive review of different approaches, explaining them step-by- step Includes diagrams that show surgical approaches Presents the advantages and disadvantages of each approach to aid in decision-making

Author : Eric L. Chang,Paul D. Brown,Simon S. Lo,Arjun Sahgal,John H. Suh
Publisher : Springer
Page : 766 pages
File Size : 55,5 Mb
Release : 2018-07-27
Category : Medical
ISBN : 9783319428789

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Adult CNS Radiation Oncology by Eric L. Chang,Paul D. Brown,Simon S. Lo,Arjun Sahgal,John H. Suh Pdf

This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.