Modified Release Drug Delivery Technology

Author : Michael J. Rathbone,Jonathan Hadgraft,Michael S. Roberts
Publisher : CRC Press
Page : 1021 pages
File Size : 48,8 Mb
Release : 2002-11-07
Category : Medical
ISBN : 9780824708696

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Modified-Release Drug Delivery Technology by Michael J. Rathbone,Jonathan Hadgraft,Michael S. Roberts Pdf

Describing formulation challenges and their solutions in the design, development, and commercialization of modified-release drugs delivery systems, this book contains eighty papers that review recent developments in design and manufacturing techniques. It includes detailed descriptions of extended release drug products for the oral, nasal, ophthalmic, pulmonary, vaginal, dermal and transdermal pathways. With the exception of the final section addressing regulatory issues, each section covers a particular route for drug delivery and opens with an overview of the anatomical, physiological, and pharmaceutical basics of each route before moving on to cover specific technologies.

Author : Michael J. Rathbone,Jonathan Hadgraft,Michael S. Roberts,Majella E. Lane
Publisher : CRC Press
Page : 0 pages
File Size : 42,6 Mb
Release : 2008-05-28
Category : Medical
ISBN : 1420053566

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Modified-Release Drug Delivery Technology, Second Edition by Michael J. Rathbone,Jonathan Hadgraft,Michael S. Roberts,Majella E. Lane Pdf

This two volume Second Edition describes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value. Topics include:

Author : Xiaoling Li
Publisher : McGraw Hill Professional
Page : 453 pages
File Size : 47,6 Mb
Release : 2005-11-24
Category : Technology & Engineering
ISBN : 9780071588836

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Design of Controlled Release Drug Delivery Systems by Xiaoling Li Pdf

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Author : Joseph R. Robinson
Publisher : Unknown
Page : 808 pages
File Size : 50,5 Mb
Release : 1978
Category : Controlled release preparations
ISBN : UOM:39015006691334

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Sustained and Controlled Release Drug Delivery Systems by Joseph R. Robinson Pdf

Author : Clive G. Wilson,Patrick J. Crowley
Publisher : Springer Science & Business Media
Page : 415 pages
File Size : 50,7 Mb
Release : 2011-09-22
Category : Medical
ISBN : 9781461410041

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Controlled Release in Oral Drug Delivery by Clive G. Wilson,Patrick J. Crowley Pdf

Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.

Author : Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 47,9 Mb
Release : 2011-12-15
Category : Medical
ISBN : 9781461408819

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Fundamentals and Applications of Controlled Release Drug Delivery by Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone Pdf

This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

Author : Anonim
Publisher : Unknown
Page : 499 pages
File Size : 55,6 Mb
Release : 2008
Category : Controlled release preparations
ISBN : OCLC:1064659467

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Modified-release Drug Delivery Technology by Anonim Pdf

Author : Edmund S. Kostewicz,Maria Vertzoni,Heather A. E. Benson,Michael S. Roberts
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 46,8 Mb
Release : 2022-04-26
Category : Medical
ISBN : 9781119772699

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Oral Drug Delivery for Modified Release Formulations by Edmund S. Kostewicz,Maria Vertzoni,Heather A. E. Benson,Michael S. Roberts Pdf

ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailability. The second section explores the design of modified release formulations, covering early drug substance testing, the biopharmaceutics classification system, an array of formulation technologies that can be used for MR dosage forms, and more. The final section focuses on in vitro, in silico, and in vivo evaluation and regulatory considerations for MR formulations. Topics include biorelevant dissolution testing, preclinical evaluation, and physiologically-based pharmacokinetic modelling (PBPK) of in vivo behaviour. Featuring contributions from leading researchers with expertise in the different aspects of MR formulations, this volume: Provides authoritative coverage of physiology, physicochemical determinants, and in-vitro in-vivo correlation (IVIVC) Explains the different types of MR formulations and defines the key terms used in the field Discusses the present status of MR technologies and identifies current gaps in research Includes a summary of regulatory guidelines from both the US and the EU Shares industrial experiences and perspectives on the evaluation of MR dosage formulations Oral Drug Delivery for Modified Release Formulations is an invaluable reference and guide for researchers, industrial scientists, and graduate students in general areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.

Author : Hong Wen,Kinam Park
Publisher : John Wiley & Sons
Page : 571 pages
File Size : 49,7 Mb
Release : 2011-01-14
Category : Science
ISBN : 9781118060322

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Oral Controlled Release Formulation Design and Drug Delivery by Hong Wen,Kinam Park Pdf

This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

Author : Marcos Luciano Bruschi
Publisher : Woodhead Publishing
Page : 208 pages
File Size : 43,5 Mb
Release : 2015-06-16
Category : Medical
ISBN : 9780081001127

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Strategies to Modify the Drug Release from Pharmaceutical Systems by Marcos Luciano Bruschi Pdf

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 47,9 Mb
Release : 2008-03-07
Category : Science
ISBN : 9781588298911

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Drug Delivery Systems by Kewal K. Jain Pdf

In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.

Author : Xiaoling Li
Publisher : Unknown
Page : 128 pages
File Size : 49,9 Mb
Release : 2000
Category : Electronic
ISBN : OCLC:958569677

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Design of Controlled Release Drug Delivery Systems by Xiaoling Li Pdf

Author : Piush Khare,Mohini Chaurasia,Sarvesh K Paliwal
Publisher : Pharmamed Press
Page : 402 pages
File Size : 44,8 Mb
Release : 2019-10-28
Category : Medical
ISBN : 9387593142

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Oral Modified Release Drug Delivery System by Piush Khare,Mohini Chaurasia,Sarvesh K Paliwal Pdf

Oral drug delivery has been an important part of drug delivery and was often linked with tablets, capsules, syrups etc during the discussion about delivery through gastrointestinal tract. Advancements in pharmaceutical sciences and enormous research in the field of drug delivery has laid newer concepts leading to the advent of advanced dosage forms with modified release leading to enhanced therapeutic efficacy. Similarly oral drug delivery has witnessed a change. The book as it is in present form is compilation of theories postulated with regards to oral drug delivery and data related to research work. Different facets of oral drug delivery from conventional to novel have been described through self explicit figures and relevant examples. Underlying basic concepts of different processes have been explained for better understanding of the subject. This book will serve as ready reference for undergraduate and postgraduate students and will cater to the scientific need of those interested in research in oral drug delivery.

Author : Donald L. Wise
Publisher : CRC Press
Page : 908 pages
File Size : 51,6 Mb
Release : 2000-08-24
Category : Medical
ISBN : 0824703693

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Handbook of Pharmaceutical Controlled Release Technology by Donald L. Wise Pdf

The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules! Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology covers oral, transdermal, parenteral, and implantable delivery of drugs discusses modification methods to achieve desired release kinetics highlights constraints of system design for practical clinical application analyzes diffusion equations and mathematical modeling considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents evaluates polymers as drug delivery carriers describes peptide, protein, micro-, and nanoparticulate release systems examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices and more!

Author : Kinam Park
Publisher : Unknown
Page : 656 pages
File Size : 40,8 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015040351143

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Controlled Drug Delivery by Kinam Park Pdf

This volume discusses the challenges of creating controlled release dosage forms that will deliver new therapeutic agents based on high-molecular-weight molecules. It examines strategies for delivering drugs through resistant biological barriers and surveys a variety of topics, including drug targeting, self-regulated drug delivery, protein drug delivery, biosensors, cell and tissue engineering, new biomaterials, modeling methods, pharmacokinetics, and U.S. federal regulations.