Molecular Aspects Of Mouse Spermatogenesis

Author : Ricardo Benavente
Publisher : S. Karger AG (Switzerland)
Page : 0 pages
File Size : 41,7 Mb
Release : 2003
Category : Mice
ISBN : 380557746X

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Molecular Aspects of Mouse Spermatogenesis by Ricardo Benavente Pdf

In recent years considerable progress has been made in the identification, immunolocalization and biochemical characterization of proteins expressed in mammalian spermatogenic cells. However, under culture conditions spermatogenic cells are difficult to investigate and manipulate, a limitation that has often complicated their functional analysis. By using the mouse as a model system, some of these limitations have been overcome. The techniques of producing genetically manipulated (knockout, transgenic, etc.) animals and the host of information provided by the mouse genome project have contributed to the rapid progress in the functional analysis of the spermatogenic proteins of the mouse compared to other mammals. This special topic issue of Cytogenetic and Genome Research presents an excellent overview of recent advances in mouse spermatogenesis research. It will be of special interest to cell and molecular biologists, geneticists and andrologists.

Author : Dominic Poccia
Publisher : Springer
Page : 176 pages
File Size : 55,7 Mb
Release : 1994
Category : Science
ISBN : STANFORD:36105009760294

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Molecular Aspects of Spermatogenesis by Dominic Poccia Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 45,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Wei Li,Liangran Zhang,Akira Shinohara,Scott Keeney
Publisher : Frontiers Media SA
Page : 427 pages
File Size : 41,5 Mb
Release : 2022-01-19
Category : Science
ISBN : 9782889741021

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Meiosis: from Molecular Basis to Medicine by Wei Li,Liangran Zhang,Akira Shinohara,Scott Keeney Pdf

Author : Manuela Simoni,Ilpo T. Huhtaniemi
Publisher : Springer
Page : 1364 pages
File Size : 46,5 Mb
Release : 2017-09-18
Category : Medical
ISBN : 3319444409

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Endocrinology of the Testis and Male Reproduction by Manuela Simoni,Ilpo T. Huhtaniemi Pdf

This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Author : Claude Desjardins,Larry L. Ewing
Publisher : Oxford University Press, USA
Page : 524 pages
File Size : 48,9 Mb
Release : 1993
Category : Medical
ISBN : 0195062698

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Cell and Molecular Biology of the Testis by Claude Desjardins,Larry L. Ewing Pdf

This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

Author : Lonnie Dee Russell,Michael D. Griswold
Publisher : Unknown
Page : 840 pages
File Size : 48,8 Mb
Release : 1993
Category : Sertoli cells
ISBN : UOM:39015029281964

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The Sertoli Cell by Lonnie Dee Russell,Michael D. Griswold Pdf

Author : Wolfgang Hennig
Publisher : Springer Science & Business Media
Page : 140 pages
File Size : 54,6 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783540471844

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Spermatogenesis Genetic Aspects by Wolfgang Hennig Pdf

Spermatogenesis is one of the fundamental but at the same time also one of the most complex differentiation processes in higher eukaryotes. For a long time the development of spermatozoa has been considered as related solely to the needs of transfer of the paternal genome into the egg. Other paternal contributions to the development of the embryo were not seriously considered. Only recently has it become evident, from studies of mouse embryonic development by Solter and colleagues, that also the paternal genome carries regulatory information into the zygote since the development of a mouse embryo requires the presence of the maternal as well as of the paternal pronucleus. This means that we have to pay more attention to the development of male gametes, since the imprinting of the paternal genome obviously required for the early embryonic development must occur during male gamete development. Despite the fundamental character of sperm development as a cellular differentiation process, no coherent concepts for studies of this process exist. Many morphological, and in particular ultrastructural, details of sperm devel opment and sperm structure are known, but this knowledge has not been assembled into a consistent picture reflecting the basic features of this differ entiation process. One of the reasons for the failure to construct such a picture is the fact that also the genetics of sperm development is poorly developed. For elaborating concepts of early embryonic development the study of mutants has been, and still is, indispensible.

Author : Rajender Singh
Publisher : CRC Press
Page : 338 pages
File Size : 40,7 Mb
Release : 2019-11-06
Category : Medical
ISBN : 9780429534423

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Molecular Signaling in Spermatogenesis and Male Infertility by Rajender Singh Pdf

Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis

Author : Michael D. Griswold
Publisher : Academic Press
Page : 488 pages
File Size : 45,5 Mb
Release : 2014-11-19
Category : Science
ISBN : 9780124170483

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Sertoli Cell Biology by Michael D. Griswold Pdf

Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years

Author : Anonim
Publisher : Unknown
Page : 866 pages
File Size : 49,8 Mb
Release : 1990
Category : Medicine
ISBN : UOM:39015072175162

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Biomedical Index to PHS-supported Research by Anonim Pdf

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Biologic Markers,Subcommittee on Reproductive and Neurodevelopmental Toxicology
Publisher : National Academies Press
Page : 424 pages
File Size : 51,9 Mb
Release : 1989-02-01
Category : Social Science
ISBN : 0309039797

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Biologic Markers in Reproductive Toxicology by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Biologic Markers,Subcommittee on Reproductive and Neurodevelopmental Toxicology Pdf

Does exposure to environmental toxicants inhibit our ability to have healthy children who develop normally? Biologic markersâ€"indicators that can tell us when environmental factors have caused a change at the cellular or biochemical level that might affect reproductive abilityâ€"are a promising tool for research aimed at answering that important question. Biologic Markers in Reproductive Toxicology examines the potential of these markers in environmental health studies; clarifies definitions, underlying concepts, and possible applications; and shows the benefits to be gained from their use in reproductive and neurodevelopmental research.

Author : Henry G. Burger,David M. De Kretser
Publisher : Raven Press (ID)
Page : 616 pages
File Size : 51,5 Mb
Release : 1989
Category : Testicular Diseases
ISBN : UCAL:B5036493

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The Testis by Henry G. Burger,David M. De Kretser Pdf

Author : Larry I. Lipshultz,Stuart S. Howards,Craig S. Niederberger
Publisher : Cambridge University Press
Page : 691 pages
File Size : 50,7 Mb
Release : 2009-09-24
Category : Medical
ISBN : 9781139483247

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Infertility in the Male by Larry I. Lipshultz,Stuart S. Howards,Craig S. Niederberger Pdf

The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Author : C.Yan Cheng,Fei Sun
Publisher : Springer
Page : 0 pages
File Size : 49,7 Mb
Release : 2022-08-30
Category : Science
ISBN : 3030777812

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Molecular Mechanisms in Spermatogenesis by C.Yan Cheng,Fei Sun Pdf

This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.