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Molecular Biology of the Neuron by Brian Morris Pdf
This book is a valuable compendium of up-to-date reviews of neuronal molecular biology by leading researchers in the field. It covers all aspects of neuron structure and function, with the emphasis on genetic and molecular analysis.
The Neuron by Irwin B. Levitan,Leonard K. Kaczmarek Pdf
Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Author : Ira Black Publisher : Springer Science & Business Media Page : 376 pages File Size : 40,5 Mb Release : 2013-11-11 Category : Medical ISBN : 9781461327172
Cellular and Molecular Biology of Neuronal Development by Ira Black Pdf
A central problem in neurobiology concerns mechanisms that generate the pro found diversity and specificity of the nervous system. What is the substance of diversification and specificity at the molecular, cellular, and systems levels? 4 How, for example, do 1011 neurons each form approximately 10 interconnec tions, allowing normal physiological function? How does disruption of these processes result in human disease? These proceedings represent the efforts of molecular biologists, embryologists, neurobiologists, and clinicians to approach these issues. in this volume are grouped by subject to present the varieties The chapters of methods used to approach each individual area. Section I deals with embry ogenesis and morphogenesis of the nervous system. In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system. Immunocyto chemical analysis reveals the existence of distinct sUbpopulations within the crest at extremely early stages; cells express neuronal or glial binding patterns at the time of migration. Consequently, interactions with the environment may select for predetermined populations. Le Douarin reaches similar conclusions in Chapter 1 by analyzing migratory pathways and developmental potentials in crest of quail-
Author : R. Wayne Davies,Brian J. Morris Publisher : Taylor & Francis Page : 399 pages File Size : 45,8 Mb Release : 1997 Category : Brain ISBN : 1859962408
Molecular Biology of the Neuron by R. Wayne Davies,Brian J. Morris Pdf
Molecular Biology of the Neuron covers all aspects of neuron structure and function, including ion channels, receptors and signalling properties, synapse biology, and the genes and molecules involved in the development, maintenance, diseases, and death of neurons. The inheritance and expression of neuronal genes are also described, with particular emphasis on their relation to human disease. This book is a valuable compendium of comprehensive and up-to-date reviews of neuronal molecularbiology by leading researchers in the field. The focus throughout is on genetic and molecular analysis, and on present knowledge of molecular biological phenomena in neurons themselves, giving Molecular Biology of the Neuron its unique perspective. It is essential reading for clinical and systems neuroscientists, and a valuable reference source for all molecular neurobiologists.
Molecular Neuroscience by Patricia Revest,Alan Longstaff Pdf
This textbook provides an introduction to neuroscience, focusing particularly on the rapidly developing molecular aspects. The techniques of molecular biology are introduced and described in the context of their role in elucidating brain function at the molecular level.
W. Maxwell Cowan,Thomas M. Jessell,Stephen Lawrence Zipursky
Author : W. Maxwell Cowan,Thomas M. Jessell,Stephen Lawrence Zipursky Publisher : Oxford University Press, USA Page : 575 pages File Size : 41,6 Mb Release : 1997 Category : Medical ISBN : 9780195111668
The Biology of Thought by Krishnagopal Dharani Pdf
The question of "what is thought" has intrigued society for ages, yet it is still a puzzle how the human brain can produce a myriad of thoughts and can store seemingly endless memories. All we know is that sensations received from the outside world imprint some sort of molecular signatures in neurons – or perhaps synapses – for future retrieval. What are these molecular signatures, and how are they made? How are thoughts generated and stored in neurons? The Biology of Thought explores these issues and proposes a new molecular model that sheds light on the basis of human thought. Step-by-step it describes a new hypothesis for how thought is produced at the micro-level in the brain – right at the neuron. Despite its many advances, the neurobiology field lacks a comprehensive explanation of the fundamental aspects of thought generation at the neuron level, and its relation to intelligence and memory. Derived from existing research in the field, this book attempts to lay biological foundations for this phenomenon through a novel mechanism termed the "Molecular-Grid Model" that may explain how biological electrochemical events occurring at the neuron interact to generate thoughts. The proposed molecular model is a testable hypothesis that hopes to change the way we understand critical brain function, and provides a starting point for major advances in this field that will be of interest to neuroscientists the world over. Written to provide a comprehensive coverage of the electro-chemical events that occur at the neuron and how they interact to generate thought Provides physiology-based chapters (functional anatomy, neuron physiology, memory) and the molecular mechanisms that may shape thought Contains a thorough description of the process by which neurons convert external stimuli to primary thoughts
Neurons: Methods and Applications for the Cell Biologist by Anonim Pdf
Neurons: Methods and Applications for the Cell Biologist lays out numerous simple techniques for growing and carrying out experiments with many varieties of neurons. Subjects include peripheral and central neurons from vertebrate and invertebrate sources, as well as neuron-like cell lines. It also explains recent advances in our ability to introduce exogenous proteins and genes to neurons in culture. Procedures for successful protein infiltration, biolistic transfection, electroporation, and viral transgenic methods in neurons are also presented. Contains culture methodology for more than a dozen types of CNS and PNS neurons Includes most recent and reliable techniques from expert practitioners for specific experimental applications Addresses the latest strategies for transfecting neurons
Thanks to tremendous technical advances in molecular biology and cellular imaging after those in electrophysiology, there is now a deep understanding of the physiology of nerve cells and their synaptic interconnections. The complexity of the brain emerges from the communication and interaction between billions of these elements. This book explores systematically and didactically the details of neuronal physiology, covering membrane biophysics, receptor physiology, sensory transduction and synaptic transmission with its selective pharmacology. Readers of the book will be fully equipped to understand the functions and possibilities of the key units of the brain’s parallel computations.
Neuronal Cell Culture by Shohreh Amini,Martyn K. White Pdf
This second edition volume details the latest aspects of neural cells covering the practical and theoretical considerations of each techniques involved. Chapters guide readers through a general overview of the neuronal culturing principles, cell line models for neural cells, the isolation and propagation of primary cultures, stem cells, transfection and transduction of neural cultures, and other more advanced techniques. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and easy to use, Neuronal Cell Culture: Methods and Protocols, Second Edition aims to be of interest to scientists at all levels studying cell culture models for neuroscientific studies.
Elements of Molecular Neurobiology by C. U. M. Smith Pdf
Synthesizes molecular and neurobiology and incorporates discussion of recombinant-DNA techniques. Explores the development of the brain and the physical basis of memory and traces malfunctions at the molecular level.
Principles of Cellular, Molecular, and Developmental Neuroscience by Oswald Steward Pdf
The field of cellular, molecular, and developmental neuroscience repre sents the interface between the three large, well established fields of neu roscience, cell biology, and molecular biology. In the last 10 to 15 years, this new field has emerged as one of the most rapidly growing and exciting subdisciplines of neuroscience. It is now becoming possible to understand many aspects of nervous system function at the molecular level, and there already are dramatic applications of this information to the treatment of nervous system injury, disease, and genetic disorders. Moreover, there is great optimism that new strategies will emerge soon as a result of the explosion of information. This book was written to introduce students to the major issues, ex perimental strategies, and current knowledge base in cellular, molecular, and developmental neuroscience. The concept for the book arose from a section of an introductory neuroscience course given to first-year medical students at the University of Virginia School of Medicine. The text pre sumes a basic, but not detailed, understanding of nervous system orga nization and function, and a background in biology. It is intended as an appropriate introductory text for first-year medical students or graduate students in neuroscience, neurobiology, psychobiology, or related pro grams;··and for advanced undergraduate students with appropriate back ground in biology and neuroscience. While some of the specific information presented undoubtedly will be outdated rapidly, the "gestalt" of this emerging field of inquiry as presented here should help the beginning stu dent organize new information.
Molecular Bases of Neural Development by Gerald M. Edelman,W. Einar Gall,W. Maxwell Cowan Pdf
This volume addresses central issues in the embryological development of the nervous system, which, while similar to that of other organs and tissues, features special and intricate mechanisms of morphogenesis. It emphasizes the description of cellular interactions at the molecular level and includes some of the first fruits from applications to neurobiology of recent developments in othera areas--notable immunology, biochemistry, molecular biology, and molecular genetics.
