Molecular Biophysics For The Life Sciences

Author : Norma Allewell,Linda O. Narhi,Ivan Rayment
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 51,8 Mb
Release : 2013-09-28
Category : Science
ISBN : 9781461485483

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Molecular Biophysics for the Life Sciences by Norma Allewell,Linda O. Narhi,Ivan Rayment Pdf

This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

Author : Robert D. Wells,Judith S. Bond,Judith Klinman,Bettie Sue Siler Masters,Ellis Bell,Laurie S. Kaguni
Publisher : Springer
Page : 0 pages
File Size : 47,9 Mb
Release : 2018-01-12
Category : Science
ISBN : 1461415292

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Molecular Life Sciences by Robert D. Wells,Judith S. Bond,Judith Klinman,Bettie Sue Siler Masters,Ellis Bell,Laurie S. Kaguni Pdf

Molecular Life Sciences: An Encyclopedic Reference will focus on understanding biological phenomena at the level of molecules and their interactions that govern life processes. The work will include articles on genes and genomes, protein structure and function, systems biology using genomics and proteomics as the focus, molecular aspects of cell structure and function, unifying concepts and theories from biology, chemistry, mathematics and physics that are essential for understanding the molecular life sciences (including teaching perspectives and assessment tools), and basic aspects of the various experimental approaches that are used in the Molecular Life Sciences.

Author : Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai,Giuseppe Zaccai
Publisher : Cambridge University Press
Page : 709 pages
File Size : 50,6 Mb
Release : 2017-05-18
Category : Medical
ISBN : 9781107056374

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Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai,Giuseppe Zaccai Pdf

A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.

Author : Hans Frauenfelder
Publisher : Springer Science & Business Media
Page : 448 pages
File Size : 46,6 Mb
Release : 2010-05-30
Category : Science
ISBN : 9781441910448

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The Physics of Proteins by Hans Frauenfelder Pdf

Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Author : Jack A. Tuszynski,Michal Kurzynski
Publisher : CRC Press
Page : 579 pages
File Size : 50,6 Mb
Release : 2003-02-26
Category : Science
ISBN : 9780203009963

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Introduction to Molecular Biophysics by Jack A. Tuszynski,Michal Kurzynski Pdf

Molecular biophysics is a rapidly growing field of research that plays an important role in elucidating the mysteries of life's molecules and their assemblies, as well as the relationship between their structure and function. Introduction to Molecular Biophysics fills an existing gap in the literature on this subject by providing the reader with th

Author : Valerica Raicu,Aurel Popescu
Publisher : Springer Science & Business Media
Page : 254 pages
File Size : 40,9 Mb
Release : 2008-06-17
Category : Science
ISBN : 9781402082689

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Integrated Molecular and Cellular Biophysics by Valerica Raicu,Aurel Popescu Pdf

Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.

Author : M Volkenstein
Publisher : Elsevier
Page : 634 pages
File Size : 49,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323144186

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Molecular Biophysics by M Volkenstein Pdf

Molecular Biophysics presents the fundamental principles of biophysics and their application to the study of the physical properties of biological macromolecules. The merger of biology and physics involves the development of sophisticated instrumentation and the molecular approach to the study of life phenomena. This book is composed of nine chapters and begins with an overview of the thermodynamical aspects and chemical foundations of biophysics. These topics are followed by the physical aspects of macromolecules, with a particular emphasis on the biological functions, conformation, and hydrophobic interactions of proteins. The subsequent chapter describes the structural and electro-optical properties of biopolymers based on X-ray, optical, and spectroscopic analysis. The discussion then shifts to enzymes, their chemical kinetics, catalytic potential, and conformational and cooperative properties. The remaining chapters explore the physical aspects of nucleic acids and the biosynthesis of proteins. This book will prove useful to molecular biophysicists, biologists, physicists, and researchers in the fields of life sciences.

Author : Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai
Publisher : Cambridge University Press
Page : 1137 pages
File Size : 41,6 Mb
Release : 2007-03-29
Category : Science
ISBN : 9781139461580

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Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai Pdf

Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.

Author : Jay L. Nadeau
Publisher : CRC Press
Page : 1223 pages
File Size : 53,6 Mb
Release : 2017-10-10
Category : Medical
ISBN : 9781351000925

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Introduction to Experimental Biophysics by Jay L. Nadeau Pdf

Praise for the First Edition “essential reading for any physical scientist who is interested in performing biological research.” ―Contemporary Physics "an ambitious text.... Each chapter contains protocols and the conceptual reasoning behind them, which is often useful to physicists performing biological experiments for the first time." –Physics Today This fully updated and expanded text is the best starting point for any student or researcher in the physical sciences to gain firm grounding in the techniques employed in molecular biophysics and quantitative biology. It includes brand new chapters on gene expression techniques, advanced techniques in biological light microscopy (super-resolution, two-photon, and fluorescence lifetime imaging), holography, and gold nanoparticles used in medicine. The author shares invaluable practical tips and insider’s knowledge to simplify potentially confusing techniques. The reader is guided through easy-to-follow examples carried out from start to finish with practical tips and insider’s knowledge. The emphasis is on building comfort with getting hands "wet" with basic methods and finally understanding when and how to apply or adapt them to address different questions. Jay L. Nadeau is a scientific researcher and head of the Biomedical Engineering in Advanced Applications of Quantum, Oscillatory, and Nanotechnological Systems (BEAAQONS) lab at Caltech and was previously associate professor of biomedical engineering and physics at McGill University.

Author : A. L. Stanford
Publisher : Academic Press
Page : 404 pages
File Size : 45,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483276441

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Foundations of Biophysics by A. L. Stanford Pdf

Foundations of Biophysics serves as an introductory textbook for physical science students to the principles and problems of the life sciences. The book offers to teach physical science students the basic vocabulary of the life sciences and the applications of physics and chemistry to a wide range of biological problems. Topics presented in the book include biological vocabulary and concepts; biological functions at the molecular level of each biological system; and commonly used tools of experimental biophysics. Students in the field of physics, chemistry, biology, and engineering will find the book a good learning material.

Author : Mikhail V. Vol kenshtein
Publisher : Springer Science & Business Media
Page : 516 pages
File Size : 42,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461585947

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Molecules and Life by Mikhail V. Vol kenshtein Pdf

acids. The achievements of molecular biology testify to the success of material science in a realm which, until recently, appeared totally enig matic and mysterious. Further scientific developments should bring to mankind vast developments both in theoretical knowledge and in practical applications, namely, in agriculture, medicine, and technology. The purpose of this book is to explain molecular biophysics to all who might wish to learn about it, to biologists, to physicists, to chemists. This book contains descriptive sections, as well as sections devoted to rigorous mathematical treatment of a number of problems, some of which have been studied by the author and his collaborators. These sections may be omitted during a first reading. Each chapter has a selected bibliography. This book is far from an exhaustive treatise on molecular biophysics. It deals principally with questions related to the structures and functions of proteins and nucleic acids. M. V. Vol'kenshtein Leningrad, September, 1964 CONTENTS Chapter 1 Physics and Biology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Physics and Life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Molecular Physics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Molecular Biophysics ................................... 9 Thermodynamics and Biology. . . . . . . . . . . . . . . . . . . . . 12 . . . . . . . Information Theory. . . . . . . . . . . . . . . . . . . . . . . . . . . 19 . . . . . . . . . . Chapter 2 Cells, Viruses, and Heredity. . . . . . . . . . . . . . . . . . . . . . . . 27 . . . . . . . . The Living Cell. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 . . . . . . . . . . . Cell Division. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 . . . . . . . . . . . . Viruses and Bacteriophages ........... . . . . . . . . . . . . . . . 44 . . . . Basic Laws of Genetics . . . . . . . . . . . . . . . . . . . . . . . . . 50 . . . . . . . . . Mutations and Mutability ........ , ................. " . . . . 60 Genetics of Bacteria and Phages " . . . . . . . . . . . . . . . . . . 66 . . . . . . Chapter 3 Biological Molecules. . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 . . . . . . . . . . Amino Acids and Proteins . . . . . . . . . . . . . . . . . . . . . . . 79 . . . . . . . . Asymmetry of Biological Molecules ....................... 87 Primary Structure of Proteins ............................ 94 Nucleic Acids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 . . . . . . . . . . . . Some Biochemical Processes in the Cell. . . . . . . . . . . . . . . . 109 . . . . Chapter 4 Physics of Macromolecules. . . . . . . . . . . . . . . . . . . . . . . . 123 . . . . . . . . .

Author : V. Pattabhi,N. Gautham
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 47,6 Mb
Release : 2002-03-31
Category : Medical
ISBN : 1402002181

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Biophysics by V. Pattabhi,N. Gautham Pdf

The first chapter introduces and refreshes the reader's knowledge of physics and chemistry. The next chapters cover various physico-chemical techniques used to study biomolecular structures, followed by treatments of spectroscopy, microscopy, diffraction, and computational techniques.

Author : Richard Burton Setlow,Ernest Charles Pollard
Publisher : Pergamon
Page : 568 pages
File Size : 55,9 Mb
Release : 1962
Category : Science
ISBN : UOM:39015004363696

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Molecular Biophysics by Richard Burton Setlow,Ernest Charles Pollard Pdf

Author : Pranav Kumar
Publisher : Pathfinder Publication unit of PAPL
Page : 115 pages
File Size : 50,5 Mb
Release : 2024-06-07
Category : Science
ISBN : 9789380473154

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Fundamentals and Techniques of Biophysics and Molecular Biology by Pranav Kumar Pdf

Fundamentals and Techniques of Biophysics and Molecular Biology textbook has the primary goal to teach students about theoretical principles and applications of the key biophysical and molecular methods used in biochemistry and molecular biology. A substantial theoretical basis has been covered to understand key experimental techniques such as Chromatography, Electrophoresis, Spectroscopy, Mass spectrometry, Centrifugation, Microscopy, Flow cytometry, Chromatin immunoprecipitation, Immunotechniques, FRET and FRAP, Polymerase chain reaction, Phage display, Yeast two-hybrid assay, DNA sequencing, Biosensors, CRISPR/Cas systems so that students can make appropriate choices and efficient use of techniques. The most significant feature of this book is its clear, up-to-date and accurate explanations of mechanisms, rather than the mere description of facts and events. This book is published by Pathfinder Publication, New Delhi, India.

Author : Roland Glaser
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 48,9 Mb
Release : 2004-10-22
Category : Science
ISBN : 3540670882

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Biophysics by Roland Glaser Pdf

Biophysics is the science of physical principles underlying the "phenomenon of life" on all levels of organization. This book begins by explaining molecular and ionic interactions, movements, excitation and energy transfer, and the self-organization of supramolecular structures. Then the biological organism is introduced as a non-equilibrium system. Finally, system analyses are discussed as well as environmental biophysics, ecological interactions, growth, differentiation, and evolution. A growing number of applications in biotechnology are based on these biophysical concepts.