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Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai Pdf
Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.
Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.
Introduction to Biophysical Methods for Protein and Nucleic Acid Research by Jay A. Glasel,Murray P. Deutscher Pdf
The first of its kind, Introduction to Biophysical Methods for Protein and Nucleic Acid Research serves as a text for the experienced researcher and student requiring an introduction to the field. Each chapter presents a description of the physical basis of the method, the type of information that may be obtained with the method, how data should be analyzed and interpreted and, where appropriate, practical tips about procedures and equipment. Key Features * Modern Use of Mass Spectroscopy * NMR Spectroscopy * Molecular Modeling and Graphics * Macintosh and DOS/Windows 3.x disks
Methods in Molecular Biophysics by Igor N. Serdyuk,Nathan R. Zaccai,Joseph Zaccai Pdf
Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.
Fundamentals and Techniques of Biophysics and Molecular Biology by Pranav Kumar Pdf
Fundamentals and Techniques of Biophysics and Molecular Biology textbook has the primary goal to teach students about theoretical principles and applications of the key biophysical and molecular methods used in biochemistry and molecular biology. A substantial theoretical basis has been covered to understand key experimental techniques such as Chromatography, Electrophoresis, Spectroscopy, Mass spectrometry, Centrifugation, Microscopy, Flow cytometry, Chromatin immunoprecipitation, Immunotechniques, FRET and FRAP, Polymerase chain reaction, Phage display, Yeast two-hybrid assay, DNA sequencing, Biosensors, CRISPR/Cas systems so that students can make appropriate choices and efficient use of techniques. The most significant feature of this book is its clear, up-to-date and accurate explanations of mechanisms, rather than the mere description of facts and events. This book is published by Pathfinder Publication, New Delhi, India.
Biophysical Techniques explains in a readily-accessible way the basics of the various biophysical methods available so students can understand the principles behind the different methods used, and begin to appreciate which tools can be used to probe different biological questions, and the pros and cons of each.
Introduction to Experimental Biophysics by Jay L. Nadeau Pdf
Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s
Integrated Molecular and Cellular Biophysics by Valerica Raicu,Aurel Popescu Pdf
Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.
Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.
Molecular and Cellular Biophysics by Meyer B. Jackson Pdf
Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.
Biophysical Chemistry of Proteins by Engelbert Buxbaum Pdf
The book is structured in nine sections, each containing several chapters. The volume starts with an overview of analytical techniques and progresses through purification of proteins; protein modification and inactivation; protein size, shape, and structure; enzyme kinetics; protein-ligand interactions; industrial enzymology; and laboratory quality control. The book is targeted at all scientists interested in protein research.
Molecular Biophysics for the Life Sciences by Norma Allewell,Linda O. Narhi,Ivan Rayment Pdf
This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.
