Molecular Genetics And The Human Personality

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Molecular Genetics and the Human Personality

Author : Jonathan Benjamin,Richard P. Ebstein,Robert H. Belmaker
Publisher : American Psychiatric Pub
Page : 452 pages
File Size : 40,6 Mb
Release : 2008-08-13
Category : Medical
ISBN : 9781585627608

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Molecular Genetics and the Human Personality by Jonathan Benjamin,Richard P. Ebstein,Robert H. Belmaker Pdf

In the 1960's and 1970's, personality and mental illness were conceptualized in an intertwined psychodynamic model. Biological psychiatry for many un-weaved that model and took mental illness for psychiatry and left personality to psychology. This book brings personality back into biological psychiatry, not merely in the form of personality disorder but as part of a new intertwined molecular genetic model of personality and mental disorder. This is the beginning of a new conceptual paradigm!! This breakthrough volume marks the beginning of a new era, an era made possible by the electrifying pace of discovery and innovation in the field of molecular genetics. In fact, several types of genome maps have already been completed, and today's experts confidently predict that we will have a smooth version of the sequencing of the human genome -- which contains some 3 billion base pairs Such astounding progress helped fuel the development of this remarkable volume, the first ever to discuss the brand-new -- and often controversial -- field of molecular genetics and the human personality. Questioning, critical, and strong on methodological principles, this volume reflects the point of view of its 35 distinguished contributors -- all pioneers in this burgeoning field and themselves world-class theoreticians, empiricists, clinicians, developmentalists, and statisticians. For students of psychopathology and others bold enough to hold in abeyance their understandable misgivings about the conjunction of "molecular genetics" and "human personality," this work offers an authoritative and up-to-date introduction to the molecular genetics of human personality. The book, with its wealth of facts, conjectures, hopes, and misgivings, begins with a preface by world-renowned researcher and author Irving Gottesman. The authors masterfully guide us through Chapter 1, principles and methods; Chapter 4, animal models for personality; and Chapter 11, human intelligence as a model for personality, laying the groundwork for our appreciation of the remaining empirical findings of human personality qua personality. Many chapters (6, 7, 9, 11, and 13) emphasize the neurodevelopmental and ontogenetic aspects of personality, with a major emphasis on the receptors and transporters for the neurotransmitters dopamine and serotonin. Though these neurotransmitters are a rational starting point now, the future undoubtedly will bring many other candidate genes that today cannot even be imagined, given our ignorance of the genes involved in the prenatal development of the central nervous system. Chapter 3 provides an integrative overview of the broad autism phenotype, and as such will be of special interest to child psychiatrists. Chapters 5, 8, and 10 offer enlightening information on drug and alcohol abuse. Chapter 14 discusses variations in sexuality. Adding balance and mature perspectives on how all the chapters complement and sometimes challenge one another are Chapter 2, written by a major figure in the renaissance of the relevance to psychopathology of both genetics and personality; Chapters 15-17, informed critical appraisals citing concerns and cautions about premature applications of this information in the policy arena; and Chapter 18, a judicious contemplation by the editors themselves of this promising -- and, to some, alarming -- field. Clear and meticulously researched, this eminently satisfying work is written to introduce the subject to postgraduate students just beginning to develop their research skills, to interested psychiatric practitioners, and to informed laypersons with some scientific background.

Behavior Genetics of Temperament and Personality

Author : Kimberly J. Saudino,Jody M. Ganiban
Publisher : Springer Nature
Page : 353 pages
File Size : 51,6 Mb
Release : 2021-03-17
Category : Psychology
ISBN : 9781071609330

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Behavior Genetics of Temperament and Personality by Kimberly J. Saudino,Jody M. Ganiban Pdf

This volume examines behavioral genetic research on temperament and personality from a number of perspectives. It takes a developmental perspective on a number of issues across the lifespan, focusing on personality and temperament. The first section focuses on the development of temperament and personality. Typically this has involved exploring genetic and environmental contributions to phenotypic stability and instability, but more recently there has been research that examines the etiology of intra-individual change/growth trajectories. The second section examines genetic and environmental contributions to the association between temperament and personality and other behaviors. The third and fourth sections discuss genotype-environment correlations and interactions, and introduces the reader to molecular genetics research on temperament and personality. Chapter 11 will discuss the significance of this type of research and Chapter 12 will provide an example of specific line of research exploring genes associated with temperament.​

Introduction to Psychology

Author : Jennifer Walinga,Charles Stangor
Publisher : Hasanraza Ansari
Page : 810 pages
File Size : 43,7 Mb
Release : 2024-06-16
Category : Body, Mind & Spirit
ISBN : 8210379456XXX

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Introduction to Psychology by Jennifer Walinga,Charles Stangor Pdf

This book is designed to help students organize their thinking about psychology at a conceptual level. The focus on behaviour and empiricism has produced a text that is better organized, has fewer chapters, and is somewhat shorter than many of the leading books. The beginning of each section includes learning objectives; throughout the body of each section are key terms in bold followed by their definitions in italics; key takeaways, and exercises and critical thinking activities end each section.

Handbook of Behavior Genetics

Author : Yong-Kyu Kim
Publisher : Springer Science & Business Media
Page : 557 pages
File Size : 53,8 Mb
Release : 2009-03-25
Category : Medical
ISBN : 9780387767277

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Handbook of Behavior Genetics by Yong-Kyu Kim Pdf

This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

The God Gene

Author : Dean H. Hamer
Publisher : Anchor
Page : 258 pages
File Size : 49,6 Mb
Release : 2005-09-27
Category : Science
ISBN : 9780307276933

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The God Gene by Dean H. Hamer Pdf

The overwhelming majority of Americans believe in God; this conviction has existed since the beginning of recorded time and is shared by billions around the world. In The God Gene, Dr. Dean Hamer reveals that this inclination towards religious faith is in good measure due to our genes and may even offer an evolutionary advantage by helping us get through difficulties, reducing stress, preventing disease, and extending life. Popular science at its best, The God Gene is an in-depth, fully accessible inquiry into cutting-edge research that can change the way we see ourselves and the world around us. Written with balance, integrity, and admirable scientific objectivity, this is a book for readers of science and religion alike.

Born That Way

Author : William Wright
Publisher : Routledge
Page : 324 pages
File Size : 46,7 Mb
Release : 2013-06-17
Category : Psychology
ISBN : 9781134979721

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Born That Way by William Wright Pdf

Taking the nature vs. nurture debate to a new level, this fascinating, comprehensive journey into the world of genetic research and molecular biology offers a fresh assessment of the work that has been done in this relatively new field during the last half century-work that has demolished common assumptions and overturned existing theories about what determines our personality and behavior.

From Neurons to Neighborhoods

Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publisher : National Academies Press
Page : 610 pages
File Size : 40,5 Mb
Release : 2000-11-13
Category : Social Science
ISBN : 9780309069885

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From Neurons to Neighborhoods by National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Pdf

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Biology of Personality and Individual Differences

Author : Turhan Canli
Publisher : Guilford Press
Page : 481 pages
File Size : 48,5 Mb
Release : 2006-01-23
Category : Psychology
ISBN : 9781593852528

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Biology of Personality and Individual Differences by Turhan Canli Pdf

This is the first book to provide an overview of current research using cutting-edge genetic and neuroimaging methods in the study of personality. Integrating compelling lines of inquiry that until now have largely remained disparate, the volume brings together leading investigators from personality psychology; clinical psychology and psychiatry; cognitive, affective, and behavioral neuroscience; and comparative psychology. Coverage includes the structure of personality and its mapping onto biology, genetic markers for individual differences and vulnerability towards psychopathology, sex differences and age-related processes, and functional neuroimaging approaches.

The Misunderstood Gene

Author : Michel Morange
Publisher : Harvard University Press
Page : 256 pages
File Size : 42,8 Mb
Release : 2001
Category : Science
ISBN : 0674003365

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The Misunderstood Gene by Michel Morange Pdf

At a time when the complete human genome has been sequenced and when seemingly every week feature news stories describe genes that may be responsible for personality, intelligence, even happiness, Michel Morange gives us a book that demystifies the power of modern genetics. The Misunderstood Gene takes us on an easily comprehensible tour of the most recent findings in molecular biology to show us how--and if--genes contribute to biological processes and complex human behaviors. As Morange explains, if molecular biologists had to designate one category of molecules as essential to life, it would be proteins and their multiple functions, not DNA and genes. Genes are the centerpiece of modern biology because they can be modified. But they are only the memory that life invented so that proteins could be efficiently reproduced. Morange shows us that there is far more richness and meaning in the structure and interactions of proteins than in all the theoretical speculations on the role of genes. The Misunderstood Gene makes it clear that we do not have to choose between rigid genetic determinism and fearful rejection of any specific role for genes in development or behavior. Both are true, but at different levels of organization. Morange agrees with those who say "we are not in our genes." But he also wants us to understand that we are not without our genes, either. We are going to have to make do with them, and this book will show us how.

Genetics of Psychological Well-Being

Author : Michael Pluess
Publisher : OUP Oxford
Page : 296 pages
File Size : 55,7 Mb
Release : 2015-06-18
Category : Psychology
ISBN : 9780191510212

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Genetics of Psychological Well-Being by Michael Pluess Pdf

'In the past decade there has been an explosion of research into the psychology of well-being. While we know that psychological well-being is partly heritable, it is only recently that researchers have started to investigate the specific genetic factors that influence well-being. Such research explores not only heritability, based on traditional twin study designs, but also includes studies combining some of the most recent molecular genetic techniques and methods. This landmark book summarizes the state of knowledge regarding heritability and molecular genetics in positive psychology. Divided into four parts, it starts by exploring the basics of genetics and associated research methodology, providing the reader with the knowledge required to understand the empirical work presented throughout the volume. The second part of the book focuses on heritability estimates of the most important positive psychology concepts based on quantitative behavioural genetics studies. In the third section of the book, results from more recent molecular genetics studies are presented including candidate gene, gene-environment interaction, as well as genome-wide association studies. This section also contains chapters on epigenetics and imaging genetics, both relatively new methodologies that are just about to make their way into the field of positive psychology. The fourth and final part of the book discusses more overarching questions regarding the roles of genes and environment in the development of well-being as well as a review and discussion of the current state of knowledge and future direction in this new field of inquiry. The first book of its kind, The Genetics of Psychological well-being is a major contribution to the positive psychology literature, and important for all those in the fields of positive psychology, psychiatric genetics, and well-being.

Principles of Psychiatric Genetics

Author : John I. Nurnberger,Wade Berrettini
Publisher : Cambridge University Press
Page : 415 pages
File Size : 50,5 Mb
Release : 2012-09-13
Category : Medical
ISBN : 9780521896498

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Principles of Psychiatric Genetics by John I. Nurnberger,Wade Berrettini Pdf

A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

Evil Genes

Author : Barbara Oakley, PhD
Publisher : Prometheus Books
Page : 475 pages
File Size : 44,7 Mb
Release : 2010-06-28
Category : Science
ISBN : 9781615920020

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Evil Genes by Barbara Oakley, PhD Pdf

Have you ever heard of a person who left you wondering, "How could someone be so twisted? So evil?" Prompted by clues in her sister’s diary after her mysterious death, author Barbara Oakley takes the reader inside the head of the kinds of malevolent people you know, perhaps all too well, but could never understand. Starting with psychology as a frame of reference, Oakley uses cutting-edge images of the working brain to provide startling support for the idea that "evil" people act the way they do mainly as the result of a dysfunction. In fact, some deceitful, manipulative, and even sadistic behavior appears to be programmed genetically—suggesting that some people really are born to be bad. Oakley links the latest findings of molecular research to a wide array of seemingly unrelated historical and current phenomena, from the harems of the Ottomans and the chummy jokes of "Uncle Joe" Stalin, to the remarkable memory of investor Warren Buffet. Throughout, she never loses sight of the personal cost of evil genes as she unravels the mystery surrounding her sister’s enigmatic life—and death. Evil Genes is a tour-de-force of popular science writing that brilliantly melds scientific research with intriguing family history and puts both a human and scientific face to evil.

DNA and Destiny

Author : R. Grant Steen
Publisher : Springer
Page : 295 pages
File Size : 44,7 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489927682

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DNA and Destiny by R. Grant Steen Pdf

This book shows that, to understand the human condition better, we must develop a keener appreciation for the subtle interactions between nature and nurture. First, Dr. Steen confronts the dark history of eugenics, and the horrifying legacy of the Nazis. He then proceeds to illuminate the latest advances in molecular biology and behavioral genetics. He explains fascinating results that have emerged from "split-twin" experiments, in which eerie parallels were found between twins separated at birth. He clarifies how the Human Genome Project might help create a new understanding of the human condition and how it may ultimately help alleviate some of the major health and even behavioral problems facing society today

No Two Alike: Human Nature and Human Individuality

Author : Judith Rich Harris
Publisher : W. W. Norton & Company
Page : 343 pages
File Size : 43,9 Mb
Release : 2010-02-15
Category : Psychology
ISBN : 9780393079517

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No Two Alike: Human Nature and Human Individuality by Judith Rich Harris Pdf

"A display of scientific courage and imagination." —William Saletan, New York Times Book Review Why do people—even identical twins reared in the same home—differ so much in personality? Armed with an inquiring mind and insights from evolutionary psychology, Judith Rich Harris sets out to solve the mystery of human individuality.

The Genetic Gods

Author : John C. Avise
Publisher : Harvard University Press
Page : 289 pages
File Size : 40,9 Mb
Release : 2009-06-30
Category : Science
ISBN : 9780674020351

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The Genetic Gods by John C. Avise Pdf

They mastermind our lives, shaping our features, our health, and our behavior, even in the sacrosanct realms of love and sex, religion, aging, and death. Yet we are the ones who house, perpetuate, and give the promise of immortality to these biological agents, our genetic gods. The link between genes and gods is hardly arbitrary, as the distinguished evolutionary geneticist John Avise reveals in this compelling book. In clear, straightforward terms, Avise reviews recent discoveries in molecular biology, evolutionary genetics, and human genetic engineering, and discusses the relevance of these findings to issues of ultimate concern traditionally reserved for mythology, theology, and religious faith. The book explains how the genetic gods figure in our development--not just our metabolism and physiology, but even our emotional disposition, personality, ethical leanings, and, indeed, religiosity. Yet genes are physical rather than metaphysical entities. Having arisen via an amoral evolutionary process--natural selection--genes have no consciousness, no sentient code of conduct, no reflective concern about the consequences of their actions. It is Avise's contention that current genetic knowledge can inform our attempts to answer typically religious questions--about origins, fate, and meaning. The Genetic Gods challenges us to make the necessary connection between what we know, what we believe, and what we embody. Table of Contents: Preface Prologue 1. The Doctrines of Biological Science 2. Geneses 3. Genetic Maladies 4. Genetic Beneficence 5. Strategies of the Genes 6. Genetic Sovereignty 7. New Lords of Our Genes? 8. Meaning Epilogue Notes Glossary Index Reviews of this book: Our genes, [Avise] says, are responsible not only for how we got here and exist day to day, but also for the core of our being--our personalities and morals. It is our genetic make-up that allows for and formulates our religious belief systems, he argues. Avise does not eschew spirituality but seeks a more informed, less confrontational approach between science and the pulpit. --Science News Reviews of this book: For the general scientific reader, the book is an excellent distillation of a broad and increasingly important field, a course of causation that cannot be ignored. From advising expectant parents to getting innocent people off death row, genetics increasingly dominates our lives. The sections on genetics are expertly written, particularly for those readers without in-depth knowledge. The author explains slowly and carefully just how genetics operates, using multiple metaphors. His genetic discourse proceeds in a neighborly fashion, as one might tell stories while sitting in a rocking chair at a country store. He seems to be invigorated by genes and just can't wait to tell about them. --David W. Hodo, Journal of the American Medical Association Reviews of this book: As a whole, this book is quite informative and stimulating, and sections of it are beautifully written. Indeed, Professor Avise has a real gift for prose and scientific expositions, and I would suspect that he must be a formidable lecturer...At its core, [The Genetic Gods] is a survey, and a very nice one at that, of evolutionary genetics, the field of the author's major research interests. There is a strong sociobiological cast to the arguments, and the work and ideas of E. O. Wilson figure prominently. The presentation of evolutionary genetics is imbedded in a more general discussion of modern human and molecular genetics...However, this book is, most of all, a philosophical treatise that attempts, admittedly with the bias of a biologist, to examine the intersection of the fundamental premises of evolution and religion. Professor Avise has given us plenty to think about in this book [and]...it was a real pleasure to wrestle with the ideas he was presenting. I would suggest that other readers give it a try. --Charles J. Epstein, Trends in Genetics Reviews of this book: [Avise's] account of the role genes play in shaping the human condition is wholly involving, paying particular attention to issues of reproduction, aging and death. In addition to presenting ample biological information in a form accessible to the nonspecialist, Avise does a superb job of discussing many of the ethical implications that have arisen from our growing knowledge of human genetics. Just a few of the topics covered are genetic engineering, the patenting of life, genetic screening, abortion, human cloning, gene therapy and insurance-related controversies. --Publishers Weekly Reviews of this book: Avise explains thoroughly how evolution operates on a genetic level. His goal is to show that humans can look to this information as a way to answer fundamental questions of life instead of looking to traditional religious beliefs...Avise includes some very interesting discussions of ethical concerns related to genetic issues. --Eric D. Albright, Library Journal This is a splendid account of a subject that affects us all: the breathtaking increase in understanding of human genetics and the insight it provides into human evolution. John Avise speaks with authority of molecular evolutionary genetics and with affecting compassion of what it might mean. --Douglas J. Futuyma, State University of New York at Stony Brook The Genetic Gods is many things. It is a wonderful introduction to modern molecular biology, by a man who knows his subject backwards. It is a stimulating account of the ways in which genetics impinges on human nature--our thinking and our behavior. It is a remarkably level-headed and sympathetic account of the implications of our new findings for traditional and not-so-traditional issues in philosophy and religion. In an age of genetic counseling, cloning, construction of new life forms, the book is worth its weight in gold for this alone. But most of all, it is a huge amount of fun to read--you want to applaud or argue with the author on nigh every page. Highly recommended! --Michael Ruse, University of Guelph The Genetic Gods makes a valuable contribution to the on-going task of sorting out the implications of evolutionary biology and genetics for human self-understanding. Avise addresses, with authority and grace, the most consequential intellectual issues of our time. A challenging and insightful book. --Loyal Rue, Harvard University A wonderfully informative and engaging book. Avise offers a lucid, accessible primer on our genes, angelic and demonic, and examines religious and ethical issues, all too human, now confronted by genetic science. He makes a compelling case that anyone seeking to 'Know Thyself' should study the DNA molecular scriptures, our most ancient and universal legacy. --Dudley Herschbach, Harvard University, Nobel Laureate in Chemistry