Molecular Medicines For Cancer

Author : Deepak Chitkara,Anupama Mittal,Ram I. Mahato
Publisher : CRC Press
Page : 610 pages
File Size : 46,5 Mb
Release : 2018-09-03
Category : Medical
ISBN : 9781351978378

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Molecular Medicines for Cancer by Deepak Chitkara,Anupama Mittal,Ram I. Mahato Pdf

The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression. In cancer, several molecular mechanisms have been shown to impact its progression, aggressiveness and chemoresistance. Increasing evidence demonstrates the role of nanotechnology and outcome of molecular therapy. Several books have discussed molecular biology and mechanisms involved in cancer, but this text gives an account of molecular therapeutics in cancer relating to advancements of nanotechnology. It provides a description of the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology. Key Features: Provides current information in the multidisciplinary field of molecular medicines and its targeted delivery to cancer using nanotechnology Presents important aspects of nanotechnology in the site-specific delivery of anticancer agents Includes up to date information on oligonucleotide and gene based therapies in cancer Describes small targeted molecules, antibodies and oligonucleotides which have shown to selectively target the molecular structures thereby influencing signal transduction Facilitates discussion between researchers involved in cancer therapy and nanoscientists

Author : Georg F. Weber
Publisher : Springer
Page : 488 pages
File Size : 55,9 Mb
Release : 2015-07-22
Category : Medical
ISBN : 9783319132785

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Molecular Therapies of Cancer by Georg F. Weber Pdf

Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Humana Press
Page : 873 pages
File Size : 43,7 Mb
Release : 2016-11-11
Category : Medical
ISBN : 9781597454582

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The Molecular Basis of Human Cancer by William B. Coleman,Gregory J. Tsongalis Pdf

This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.

Author : Dennis W. Ross
Publisher : Springer Science & Business Media
Page : 183 pages
File Size : 43,8 Mb
Release : 2013-03-09
Category : Science
ISBN : 9781475724608

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Introduction to Molecular Medicine by Dennis W. Ross Pdf

In the four years since the first edition of this book was published, the molecular revolution has continued. DNA has been named by Time maga zine as the Molecule of the Year, a Nobel Prize has been awarded to a young man for the invention of the polymerase chain reaction, and televi sion viewers have learned of the DNA fingerprint. Molecular technology in medicine is increasing. The availability of DNA probes for cancer suscepti bility is stressing our system of insurance, testing our ideas about medical ethics, and teaching us new things about cancer. In this edition, I have added a number of new sections, as well as a new chapter. New examples of molecular medicine have been added to demonstrate current applications of this technology. The basic concepts of molecular biology remain the basis for the first three chapters of the book. The excitement surrounding molec ular medicine that I mentioned in the preface to the first edition continues. It is now tinged with a touch of awe and a little bit of fear at the changes that recombinant DNA technology has brought to our society. v Preface to the First Edition This book describes the discoveries that have created a field called molecu lar medicine. The use of recombinant DNA technology in medical research and most recently in medical practice constitutes a revolutionary tool in our study of disease.

Author : Dennis W. Ross
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 50,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461216629

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Introduction to Oncogenes and Molecular Cancer Medicine by Dennis W. Ross Pdf

Providing the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer, this book reviews the basic molecular and other principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukaemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies allow readers an insight into current therapies as well as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.

Author : Anonim
Publisher : Unknown
Page : 1027 pages
File Size : 42,9 Mb
Release : 2006
Category : Breast
ISBN : OCLC:1165402938

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Breast Cancer and Molecular Medicine by Anonim Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Martine Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso
Publisher : Springer Science & Business Media
Page : 1048 pages
File Size : 45,8 Mb
Release : 2007-03-07
Category : Medical
ISBN : 9783540282655

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Breast Cancer Management and Molecular Medicine by Martine Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso Pdf

Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.

Author : Jan Trost Jorgensen,Henrik Winther
Publisher : CRC Press
Page : 228 pages
File Size : 49,8 Mb
Release : 2019-05-08
Category : Medical
ISBN : 9780429533693

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Molecular Diagnostics by Jan Trost Jorgensen,Henrik Winther Pdf

This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.

Author : Joseph E. Roulston,John M. S. Bartlett
Publisher : Springer Science & Business Media
Page : 389 pages
File Size : 48,6 Mb
Release : 2008-02-01
Category : Medical
ISBN : 9781592597604

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Molecular Diagnosis of Cancer by Joseph E. Roulston,John M. S. Bartlett Pdf

We are currently experiencing a fundamental shift in the way in which we approach the characterization of cancer. Never before has the make up of cancer tissues and individual cells been so exhaustively researched and char- terized. We are now capable of producing molecular “fingerprints” that ch- acterize the expression of all known and unknown genes within tumors and their surrounding tissues. More than 30,000 different genes may be measured in each patient’s tumor in a single experiment. Simultaneously, novel therapies that exploit the molecular roadmap have been developed and are now being offered to patients. These novel agents, such as Glivec, Herceptin, Iressa, and others, specifically target individual genes within tumors and can produce d- matic responses in some patients. These drugs are only the forerunners of a coming tidal wave of novel therapeutics that individually target specific m- ecules within cancer cells—more than 300 such agents are currently in phase I or II clinical trials. This is an exciting time for cancer specialists and patients alike. However, if we have learned anything from the past 50 or more years of research into cancer, it is that Lord Beaverbrook, in founding the British national health service in the 1950s, was frighteningly prescient when he defined the primary goal of health care to be “Diagnosis, Diagnosis, Diag- sis. ” Now, more than ever, it is essential that appropriate diagnostic methods and approaches are applied to the selection of patients for treatment.

Author : Martine J. Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso
Publisher : Springer Science & Business Media
Page : 1048 pages
File Size : 52,7 Mb
Release : 2007-05-31
Category : Medical
ISBN : 9783540282662

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Breast Cancer Management and Molecular Medicine by Martine J. Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso Pdf

Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.

Author : Fabrizio d'Adda di Fagagna,Susanna Chiocca,Fraser McBlane,Ugo Cavallaro
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 47,6 Mb
Release : 2007-07-18
Category : Medical
ISBN : 9780387691169

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Advances in Molecular Oncology by Fabrizio d'Adda di Fagagna,Susanna Chiocca,Fraser McBlane,Ugo Cavallaro Pdf

Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.

Author : Jens Kurreck,Cy Aaron Stein
Publisher : John Wiley & Sons
Page : 419 pages
File Size : 52,8 Mb
Release : 2016-02-16
Category : Science
ISBN : 9783527331895

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Molecular Medicine by Jens Kurreck,Cy Aaron Stein Pdf

Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Author : Yusuf Tutar
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 40,7 Mb
Release : 2021-01-20
Category : Science
ISBN : 9781839627262

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Methods in Molecular Medicine by Yusuf Tutar Pdf

Treatment risk and response to therapy prediction can be forecasted through early diagnosis, which improves prognosis reliability and effectiveness of therapies. This book covers contemporary advances in molecular markers, disease-causing variants, retroelements, and the basis of distinct diseases.

Author : Frank Joseph Rauscher (III)
Publisher : Cambridge University Press
Page : 985 pages
File Size : 43,5 Mb
Release : 2014
Category : Medical
ISBN : 9780521876629

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Molecular Oncology by Frank Joseph Rauscher (III) Pdf

Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.