Molecular Switches Of The Immune System The E Protein Id Axis In Hematopoietic Development And Function

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Molecular Switches of the Immune System: The E Protein/Id Axis in Hematopoietic Development and Function

Author : Michele Kay Anderson,Juan Carlos Zuniga-Pflucker,Mikael Sigvardsson,Barbara L. Kee
Publisher : Frontiers Media SA
Page : 162 pages
File Size : 51,5 Mb
Release : 2022-12-01
Category : Medical
ISBN : 9782832508138

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Molecular Switches of the Immune System: The E Protein/Id Axis in Hematopoietic Development and Function by Michele Kay Anderson,Juan Carlos Zuniga-Pflucker,Mikael Sigvardsson,Barbara L. Kee Pdf

Protein Kinase-mediated Decisions Between Life and Death

Author : Ayse Basak Engin,Atilla Engin
Publisher : Springer Nature
Page : 415 pages
File Size : 40,5 Mb
Release : 2021-02-04
Category : Medical
ISBN : 9783030498443

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Protein Kinase-mediated Decisions Between Life and Death by Ayse Basak Engin,Atilla Engin Pdf

Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information. Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Annual Scientific Report

Author : Howard Hughes Medical Institute
Publisher : Unknown
Page : 680 pages
File Size : 42,6 Mb
Release : 1993
Category : Cytology
ISBN : UOM:39015026020597

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Annual Scientific Report by Howard Hughes Medical Institute Pdf

Neonatal Hematology

Author : Pedro A. de Alarcón,Eric J. Werner,Robert D. Christensen,Martha C. Sola-Visner
Publisher : Cambridge University Press
Page : 501 pages
File Size : 50,7 Mb
Release : 2021-02-18
Category : Medical
ISBN : 9781108488983

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Neonatal Hematology by Pedro A. de Alarcón,Eric J. Werner,Robert D. Christensen,Martha C. Sola-Visner Pdf

An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Encyclopedia of Endocrine Diseases

Author : Luciano Martini
Publisher : Academic Press
Page : 816 pages
File Size : 50,7 Mb
Release : 2004
Category : Medical
ISBN : 0124755720

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Encyclopedia of Endocrine Diseases by Luciano Martini Pdf

The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This encyclopedia is an essential addition to any library collection written to be accessible for both the clinical and non-clinical reader. Associate Editors include: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga. Also available online via ScienceDirect featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. * Includes nearly 500 entries addressing all aspects of endocrine diseases * More than 800 eminent researchers contributed from 25 different countries around the world * More than 900 figures and 450 tables displayed * Comprehensive glossary comprising 1500 definitions * The Editor-in-Chief is former editor of the journal Frontiers in Neuroendocrinology and has contributed to over 40 books in the field of endocrinology.

Mechanisms of Insulin Action

Author : Alan R. Saltiel,Jeffrey E. Pessin
Publisher : Springer Science & Business Media
Page : 223 pages
File Size : 52,6 Mb
Release : 2007-10-05
Category : Medical
ISBN : 9780387722047

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Mechanisms of Insulin Action by Alan R. Saltiel,Jeffrey E. Pessin Pdf

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Cumulated Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1846 pages
File Size : 43,8 Mb
Release : 1999
Category : Medicine
ISBN : OSU:32436010790556

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Cumulated Index Medicus by Anonim Pdf

Macromolecular Protein Complexes III: Structure and Function

Author : J. Robin Harris,Jon Marles-Wright
Publisher : Springer Nature
Page : 580 pages
File Size : 54,7 Mb
Release : 2020-11-30
Category : Science
ISBN : 9783030589714

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Macromolecular Protein Complexes III: Structure and Function by J. Robin Harris,Jon Marles-Wright Pdf

This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Immunopharmacology

Author : Manzoor M. Khan
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 50,8 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9780387779768

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Immunopharmacology by Manzoor M. Khan Pdf

During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Fish Diseases

Author : Galina Jeney
Publisher : Academic Press
Page : 278 pages
File Size : 45,7 Mb
Release : 2017-02-11
Category : Science
ISBN : 9780128045855

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Fish Diseases by Galina Jeney Pdf

Fish Diseases: Prevention and Control Strategies provides essential information on disease prevention and treatment by the most experienced fish culturists in the industry. The book presents both traditional and novel methodologies of identifying and addressing fish disease risk, along with preventative and responsive insights to the challenges impacting fish production today. Both specific (vaccination) and non-specific (immunostimulation) approaches are explored, from maintaining optimal environmental conditions, to understanding how stressors in fish affect their immune system. Includes relevant information on government restrictions on drug usage in aquaculture to address the strict demand for fish products free of pollutants/antibiotics Presents best practices in fish farming to prevent disease and promote good health status and fish disease management Provides the most recent research on fish diseases prevention, the pathogens most studied, and options for methods of treatment

Index Medicus

Author : Anonim
Publisher : Unknown
Page : 1732 pages
File Size : 52,8 Mb
Release : 2002
Category : Medicine
ISBN : MINN:31951P00895946S

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Adult Stem Cell Niches

Author : Sabine Wislet
Publisher : BoD – Books on Demand
Page : 332 pages
File Size : 55,7 Mb
Release : 2014-08-01
Category : Science
ISBN : 9789535117186

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Adult Stem Cell Niches by Sabine Wislet Pdf

Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches.

Cytokines: Interleukins and Their Receptors

Author : Razelle Kurzrock,Moshe Talpaz
Publisher : Springer Science & Business Media
Page : 583 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312413

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Cytokines: Interleukins and Their Receptors by Razelle Kurzrock,Moshe Talpaz Pdf

Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations. In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a comprehensive review of the biology of the interleukins and their role in both health and illness, while maintaining a balance between the basic science and clinical aspects. Cytokines: Interleukins and their Receptors should be of interest to a wide variety of researchers including clinical hematologists, oncologists, immunologists, in addition to medical and PhD students and researchers with an interest in cytokines.

Tendon Regeneration

Author : Manuela E Gomes,Rui L Reis,Márcia T Rodrigues
Publisher : Academic Press
Page : 470 pages
File Size : 54,7 Mb
Release : 2015-08-08
Category : Technology & Engineering
ISBN : 9780128016008

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Tendon Regeneration by Manuela E Gomes,Rui L Reis,Márcia T Rodrigues Pdf

Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies. Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field. Provides an overview of tendon biology, disease, and tissue engineering approaches Presents modern, alternative approaches to developing functional tissue solutions discussed Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field

Flow Cytometry and Cell Sorting

Author : Andreas Radbruch
Publisher : Springer Science & Business Media
Page : 365 pages
File Size : 55,7 Mb
Release : 2013-03-14
Category : Science
ISBN : 9783662041291

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Flow Cytometry and Cell Sorting by Andreas Radbruch Pdf

The analysis and sorting of large numbers of cells with a fluorescence-activated cell sorter (FACS) was first achieved some 30 years ago. Since then, this technology has been rapidly developed and is used today in many laboratories. A Springer Lab Manual Review of the First Edition: "This is a most useful volume which will be a welcome addition for personal use and also for laboratories in a wide range of disciplines. Highly recommended." CYTOBIOS