Molecular Theory Of The Living Cell Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Molecular Theory Of The Living Cell book. This book definitely worth reading, it is an incredibly well-written.
Molecular Theory of the Living Cell by Sungchul Ji Pdf
The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine.
The Molecular Theory of Radiation Biology by K. H. Chadwick,H. P. Leenhouts Pdf
In late 1971 we were involved in a study of the interaction of radiation with matter and were trying to use measurements of radiation fluorescence in biological molecules to indicate how radiation affected living cells. It soon became apparent that we were working in the dark; the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA molecule appeared to be the most likely target molecule we did not know which sort of events and which sort oflesions were the most important. We decided to alter our approach to see if we could find any consistent mathematical order in the radiobiological dose relationships. We found that cell survival curves could be very usefully described by a linear-quadratic dose relationship and very soon came to the somewhat premature but, as it turned out, most effective conclusion that the induction of DNA double strand breaks should be linear-quadratic. In deciding that the DNA double strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of the cell and were able to relate known properties of the DNA molecule to known radiobiological effects. On the other hand, we were restricted and brought, from an abstract two-hit lesion which could have any property one wished, down to earth, to a defined moleccular structure of nanometer dimensions and well-known functions and properties.
Molecular Theory of Evolution by Bernd-Olaf Küppers Pdf
The subject of this book is the physico-chemical theory of the origin of life. Although this theory is still in statu nascendi, it has been developed in recent years to the point where a coherent presentation is possible. The book is intended as an introductory text for students of physics, chemistry or biology. This interdisciplinary aim has necessitated a choice of material based on the lowest common denominator of physicists and biologists. In particular, the predominantly mathematical and biological sections have been presented at the most elementary l.evel possible. The less mathematically inclined reader can omit Sections (5.3)-(5.5), (5.7)-(5.10), (6.2), (6.3), (9.1)-(9.3), (12.1) and (13.3) without losing the overall view. For critical reading of the manuscript, for discussions and for many useful suggestions I wish to thank M. Eigen (Gottingen), w.e. Gardiner (Austin), D. Porschke (Gottingen), P. Schuster (Vienna), P.R. Wills (Auckland) and P. Woolley (Berlin). The translation of the original, German manuscript into English was kindly undertaken by Paul Woolley. During this and subsequent stages of revision he introduced a great many improvements in the text and the presentation of material. My particular thanks are due to him for his decisive contribution to this book. Last of all I wish to thank Ingeborg Lechten for typing the text in its various stages of evolution. The completion of this book is largely to be attributed to her patience and efficiency.
Cell Language Theory, The: Connecting Mind And Matter by Ji Sungchul Pdf
This book represents the results of 45 years of research on a wide range of topics, including atomic physics, single-molecule enzymology, whole-cell metabolism, physiology, pharmacology, linguistics, semiotics, and cosmology. It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions. Conformons provide the driving forces for all molecular machines in the cell, and intracellular dissipative structures coordinate intra- and intercellular processes such as gene expression and cell-cell communications. One of the predictions made by the cell language theory (CLT) is that there are two forms of genetic information — the Watson–Crick genes transmitting information in time (identified with DNA), and the Prigoginian genes transmitting information in space (identified with RNA expression profiles). The former is analogous to sheet music or written language and the latter is akin to audio music or spoken language, both being coupled by conformons acting as the analog of the pianist. The new theory of DNA structure and function constructed on the basis of CLT can rationally account for most of the puzzling findings recently unearthed by the ENCODE (Encyclopedia of DNA Elements) project. The Cell Language Theory has important applications in biomedical sciences including drug discovery research and personalized medicine on the one hand and in the mind-body research and consciousness studies on the other. Contents: PrefaceAbout the AuthorAcknowledgementsIntroductionKey Terms and ConceptsThe BhopalatorCell LanguageMatrix Mathematics of GeneticsBiosemioticsApplications of the Cell Language Theory to Biomedical SciencesThe Universality of the Planckian Distribution EquationThe Universality of the Irreducible Triadic RelationThe Philosophical Implications of the Cell Language TheoryConclusionsReferencesAppendicesIndex Readership: Students, researchers and practitioners of the biomedical sciences and mind-body research and consciousness studies Keywords: Conformons;Cell Language Theory;Intracellular Dissipative Structures;Watson-Crick Gene;Prigoginian GeneReview:0
A Molecular Conception of Organisms and Neoplasms by T. L. Cleave Pdf
A Molecular Conception of Organisms and Neoplasms is a six-chapter thesis that consists of a chain of reasoning on the theory of molecular conception. This thesis contends that any organism, even if multicellular, is basically a single molecule, which is the key problem of the causation of neoplasms. After providing a unifying definition of a molecule, this book goes on discussing the concept of fundamental unicellularity of multicellular organism through protoplasmic continuity between its cells. The succeeding chapters highlight the principles of the molecular conception of organisms and neoplasms. The final chapters outline the other activities of an organism determined by the molecular conception theory, such as embryonic development, animal heat, movement, pleasure and pain, and mind. This book will be of value to biochemists and clinical chemists.
The Mysterious Waves Of Living Cells by Hubert Rudakemwa Pdf
In this book, Rudakemwa shares with us intriguing questions which lead to thinking about the existence of a new way of communication used by living cells. These ideas lead to a new theory that revolutionizes the way we previously conceived the internal organization of living beings. Not only this theory is new in its own way but it also brings in many other stunning consequences about the living world as we know it. In this book, He also goes deep to cover other issues such as a review of the theory of evolution and the origins of human conflicts.
The field of cell biology is built on a foundation of discoveries stretching back to the earliest descriptions of cell theory in the 1800s. Today, our growing insight into cells and their control of life functions continues to generate advances in areas such as medicine, agriculture, genetics, and reproduction. This book traces the rise of cell biology and explains biological concepts through easy-to-follow text. Sidebars provide biographies of key scientists and descriptions of the evolution of microscopes and other significant technologies. Readers travel deep inside the cell, following the path of scientists as they unlock its mysteries.
Concepts of Biology by Samantha Fowler,Rebecca Roush,James Wise Pdf
Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Sungchul Ji,University of Medicine and Dentistry of New Jersey
Author : Sungchul Ji,University of Medicine and Dentistry of New Jersey Publisher : Unknown Page : 552 pages File Size : 50,6 Mb Release : 1991 Category : Cell death ISBN : UCAL:B4344049
Molecular Theories of Cell Life and Death by Sungchul Ji,University of Medicine and Dentistry of New Jersey Pdf
Most of the chapters were written on the basis of lectures delivered at the International Colloquium on title] held in Piscataway, New Jersey, May 1986; but some were solicited and submitted as late as mid-1989. The long delay in publication does not diminish the value here; in fact, some authors (
What is life? Fifty years after physicist Erwin Schrodinger posed this question in his celebrated and inspiring book, the answer remains elusive. In The Way of the Cell, one of the world's most respected microbiologists draws on his wide knowledge of contemporary science to provide fresh insight into this intriguing and all-important question. What is the relationship of living things to the inanimate realm of chemistry and physics? How do lifeless but special chemicals come together to form those intricate dynamic ensembles that we recognize as life? To shed light on these questions, Franklin Harold focuses here on microorganisms--in particular, the supremely well-researched bacterium E. coli--because the cell is the simplest level of organization that manifests all the features of the phenomenon of life. Harold shows that as simple as they appear when compared to ourselves, every cell displays a dynamic pattern in space and time, orders of magnitude richer than its elements. It integrates the writhings and couplings of billions of molecules into a coherent whole, draws matter and energy into itself, constructs and reproduces its own order, and persists in this manner for numberless generations while continuously adapting to a changing world. A cell constitutes a unitary whole, a unit of life, and in this volume one of the leading authorities on the cell gives us a vivid picture of what goes on within this minute precinct. The result is a richly detailed, meticulously crafted account of what modern science can tell us about life as well as one scientist's personal attempt to wring understanding from the tide of knowledge.
Fundamentals of Molecular Structural Biology by Subrata Pal Pdf
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease
Crossing the Boundaries of Life by Karl S. Matlin Pdf
"The difficulty of reconciling chemical mechanisms with the functions of whole living systems has plagued biologists since the development of cell theory in the nineteenth century. As Karl Matlin argues in Crossing the Boundaries of Life, it is no coincidence that this longstanding knot of scientific inquiry was loosened most meaningfully by the work of a cytologist, the Nobel laureate Günter Blobel. In 1975, using an experimental setup that did not contain any cells at all, Blobel was able to synthesize proteins to theorize how proteins in the cell communicate spatially, an idea he called signal hypothesis. Over the next 20 years, Blobel and other scientists were able to dissect this process into its precise molecular details. For elaborating his signal concept into a process he termed membrane topogenesis-the idea that each protein in the cell is synthesized with an "address" that directs the protein to its correct destination within the cell-Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999. Matlin argues that Blobel's investigative strategy and its subsequent application addressed the fundamental unresolved dilemma that had bedeviled biology from its very beginning, allowing biology to overcome the barrier that had long blocked progress toward mechanistic explanations of life. Crossing the Boundaries of Life thus uses Blobel's research and life story to shed light on the importance of cell biology for twentieth-century science, illustrating how it propelled the development of adjacent disciplines like biochemistry and molecular biology"--
