Molecularly Imprinted Polymers As Advanced Drug Delivery Systems

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Molecularly Imprinted Polymers as Advanced Drug Delivery Systems

Author : Zhaosheng Liu,Yanping Huang,Yi Yang
Publisher : Springer Nature
Page : 218 pages
File Size : 43,6 Mb
Release : 2021-04-23
Category : Medical
ISBN : 9789811602276

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Molecularly Imprinted Polymers as Advanced Drug Delivery Systems by Zhaosheng Liu,Yanping Huang,Yi Yang Pdf

This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives

Advanced Drug Delivery

Author : Ashim Mitra,Chi H. Lee,Kun Cheng
Publisher : John Wiley & Sons
Page : 844 pages
File Size : 41,5 Mb
Release : 2013-08-26
Category : Medical
ISBN : 9781118662847

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Advanced Drug Delivery by Ashim Mitra,Chi H. Lee,Kun Cheng Pdf

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Advanced Molecularly Imprinting Materials

Author : Ashutosh Tiwari,Lokman Uzun
Publisher : John Wiley & Sons
Page : 720 pages
File Size : 51,8 Mb
Release : 2016-11-09
Category : Science
ISBN : 9781119336310

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Advanced Molecularly Imprinting Materials by Ashutosh Tiwari,Lokman Uzun Pdf

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Molecularly Imprinted Polymer Composites

Author : Sooraj M.P.,Archana S. Nair,Beena Mathew,Sabu Thomas
Publisher : Woodhead Publishing
Page : 442 pages
File Size : 47,5 Mb
Release : 2020-12-01
Category : Technology & Engineering
ISBN : 9780128203859

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Molecularly Imprinted Polymer Composites by Sooraj M.P.,Archana S. Nair,Beena Mathew,Sabu Thomas Pdf

Molecular Imprinted Polymer Composites: Synthesis, Characterisation and Applications covers the design of composite materials containing nanostructures and molecular imprinted polymers that has materialized the ever-sought out vision of homogeneous molecular imprinted polymers. The inherent high surface-to-volume ratio of nanostructures has served well in increasing the surface area of conventional bulk polymers. In recent decades, molecularly imprinted polymer nanocomposite materials have attracted much attention for their potential applications in the fields of separation science, sensing, drug delivery, waste water treatment and catalysis, hence this book provides a much needed update on progress. Includes information on molecular imprinted polymer composites and their potential for commercialization Discusses their synthesis, characterization and applications Analyzes the effect of incorporation of different nanostructures on the thermodynamic, kinetic and adsorption behavior of imprinted sorbents

Smart Polymeric Nano-Constructs in Drug Delivery

Author : Suresh P Vyas,Udita Agrawal,Rajeev Sharma
Publisher : Academic Press
Page : 626 pages
File Size : 48,8 Mb
Release : 2022-11-12
Category : Business & Economics
ISBN : 9780323913997

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Smart Polymeric Nano-Constructs in Drug Delivery by Suresh P Vyas,Udita Agrawal,Rajeev Sharma Pdf

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. Provides comprehensive overview of the potential role of polymeric systems in drug delivery Explores the design, synthesis, and application of different smart material-based delivery systems Includes fundamental and clinical applications

Molecularly Imprinted Polymers in Biotechnology

Author : Bo Mattiasson,Lei Ye
Publisher : Springer
Page : 231 pages
File Size : 45,6 Mb
Release : 2015-07-14
Category : Science
ISBN : 9783319207292

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Molecularly Imprinted Polymers in Biotechnology by Bo Mattiasson,Lei Ye Pdf

Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity...), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bin Lu MIPs for binding macromolecules, by Kenneth J. Shea Solid phase extraction, by Ecevit Yilmaz Sensors, by Sergey A. Piletsky MIPs for catalysis and synthesis, by Marina Resmini Wastewater treatment, by Bo Mattiasson MIPs as tools for bioassays, biotransformation and drug delivery, by Meiping Zhao

Drug Delivery Systems in Cancer Therapy

Author : Dennis M. Brown
Publisher : Springer Science & Business Media
Page : 438 pages
File Size : 40,8 Mb
Release : 2003-09-08
Category : Medical
ISBN : 9781592594276

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Drug Delivery Systems in Cancer Therapy by Dennis M. Brown Pdf

Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Advanced Molecularly Imprinting Materials

Author : Ashutosh Tiwari,Lokman Uzun
Publisher : John Wiley & Sons
Page : 720 pages
File Size : 40,9 Mb
Release : 2016-11-02
Category : Science
ISBN : 9781119336167

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Advanced Molecularly Imprinting Materials by Ashutosh Tiwari,Lokman Uzun Pdf

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

Ligand

Author : Chandraleka Saravanan,Bhaskar Biswas
Publisher : BoD – Books on Demand
Page : 122 pages
File Size : 54,9 Mb
Release : 2018-05-23
Category : Science
ISBN : 9781789231823

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Ligand by Chandraleka Saravanan,Bhaskar Biswas Pdf

The book Ligand describes the diversity and versatility of ligands, covering structural features, donor-acceptor properties and secondary functions like molecular recognition. Moreover, this book also provides a comprehensive account on the applicability like catalysis, sensors, supramolecular assembly, photochemical property, bioinorganic chemistry, and so on. The advancement of fundamentals in ligand design and the control of physicochemical properties of coordination compounds has largely increased emphasis on understanding the structural and electronic features toward different perspectives in materials science. In this regard, this book has a special appeal to chemists, biologists and others. This book will be beneficial for the graduate students, teachers, researchers and other professionals who are interested to fortify and expand their knowledge in chemistry, biology, microbiology, biotechnology, materials science, environmental science and so on.

Engineering Polymer Systems for Improved Drug Delivery

Author : Rebecca A. Bader,David A. Putnam
Publisher : John Wiley & Sons
Page : 395 pages
File Size : 55,7 Mb
Release : 2014-01-17
Category : Social Science
ISBN : 9781118747803

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Engineering Polymer Systems for Improved Drug Delivery by Rebecca A. Bader,David A. Putnam Pdf

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry

Author : Vijay Kumar Thakur,Manju Kumari Thakur
Publisher : John Wiley & Sons
Page : 552 pages
File Size : 45,7 Mb
Release : 2015-06-29
Category : Technology & Engineering
ISBN : 9781119041368

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Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry by Vijay Kumar Thakur,Manju Kumari Thakur Pdf

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Biopolymers

Author : Magdy Elnashar
Publisher : BoD – Books on Demand
Page : 634 pages
File Size : 54,6 Mb
Release : 2010-09-28
Category : Technology & Engineering
ISBN : 9789533071091

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Biopolymers by Magdy Elnashar Pdf

Biopolymers are polymers produced by living organisms. Cellulose, starch, chitin, proteins, peptides, DNA and RNA are all examples of biopolymers. This book comprehensively reviews and compiles information on biopolymers in 30 chapters. The book covers occurrence, synthesis, isolation and production, properties and applications, modification, and the relevant analysis methods to reveal the structures and properties of some biopolymers. This book will hopefully be of help to many scientists, physicians, pharmacists, engineers and other experts in a variety of disciplines, both academic and industrial. It may not only support research and development, but be suitable for teaching as well.

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra,Aliasgar Shahiwala
Publisher : Elsevier
Page : 594 pages
File Size : 45,9 Mb
Release : 2020-10-02
Category : Technology & Engineering
ISBN : 9780128226681

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Applications of Polymers in Drug Delivery by Ambikanandan Misra,Aliasgar Shahiwala Pdf

Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author : Jorge Coelho
Publisher : Springer Science & Business Media
Page : 433 pages
File Size : 46,9 Mb
Release : 2013-03-15
Category : Medical
ISBN : 9789400760103

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Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by Jorge Coelho Pdf

This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

Nanocarriers for Organ-Specific and Localized Drug Delivery

Author : Muhammad Raza Shah,Muhammad Imran Malik,Shafi Ullah
Publisher : Elsevier
Page : 272 pages
File Size : 45,8 Mb
Release : 2022-04-08
Category : Technology & Engineering
ISBN : 9780128210949

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Nanocarriers for Organ-Specific and Localized Drug Delivery by Muhammad Raza Shah,Muhammad Imran Malik,Shafi Ullah Pdf

Organ-specific drug delivery is aimed at achieving increased concentration of therapeutic molecules at target sites with minimum side effects on other healthy tissues. Similarly, drug-specific delivery to some vital organs, such as the brain, lungs, heart and kidneys remains a challenging task for the formulation scientists. Oral delivery of most of the commercially available life-saving drugs has also been impeded by various physio-chemical and biological barriers. These advancements in nanotechnology have led to the development of various pharmaceutical nanocarriers.Nanocarriers for Organ-Specific and Localized Drug Delivery summarizes targeted drug delivery systems and approaches to the major organs of the body. The book shows how drugs can be specifically targeted to the pathological area within an organ in a viable way. Employing pharmaceutical nanocarriers for drug delivery targeted to specific organs of the body requires a comprehensive knowledge of the disease site’s pathophysiology as well as physical, chemical and pharmaceutical techniques for modification or functionalization of the nanocarriers.Combining theoretical principles and practical applications of various nanocarriers for organ-specific drug delivery, this is an important reference source for all those seeking to increase their understanding of how pharmaceutical nanocarriers are being used to create more efficient drug delivery systems. Outlines the underlying principles for the design of advanced pharmaceutical nanocarriers for organ specific drug delivery Includes guidance on how to exploit the pathophysiology and microenvironment of the diseased sites for targeted drug delivery Assesses the major challenges for creating pharmaceutical nanocarriers on a mass scale