Multiscale Modeling To Tackle The Complexity Of Load Bearing Organ And Tissue Regulation

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Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation

Author : Jerome Noailly,Stephane Avril,Peter Pivonka,Stefan Scheiner
Publisher : Frontiers Media SA
Page : 317 pages
File Size : 42,6 Mb
Release : 2022-03-11
Category : Science
ISBN : 9782889746620

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Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation by Jerome Noailly,Stephane Avril,Peter Pivonka,Stefan Scheiner Pdf

Practical Aspects of Computational Chemistry

Author : Jerzy Leszczynski,Manoj Shukla
Publisher : Springer Science & Business Media
Page : 468 pages
File Size : 41,5 Mb
Release : 2009-10-03
Category : Science
ISBN : 9789048126873

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Practical Aspects of Computational Chemistry by Jerzy Leszczynski,Manoj Shukla Pdf

"Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads.

Mechanobiology

Author : Glen L. Niebur
Publisher : Elsevier
Page : 256 pages
File Size : 49,5 Mb
Release : 2019-12-01
Category : Science
ISBN : 9780128179321

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Mechanobiology by Glen L. Niebur Pdf

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena

Multiscale Cancer Modeling

Author : Thomas S. Deisboeck,Georgios Stamatakos
Publisher : CRC Press
Page : 492 pages
File Size : 55,9 Mb
Release : 2010-12-08
Category : Mathematics
ISBN : 9781439814420

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Multiscale Cancer Modeling by Thomas S. Deisboeck,Georgios Stamatakos Pdf

Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat

Multiscale Modeling and Simulation of Composite Materials and Structures

Author : Young Kwon,David H. Allen,Ramesh R. Talreja
Publisher : Springer Science & Business Media
Page : 634 pages
File Size : 42,7 Mb
Release : 2007-12-04
Category : Technology & Engineering
ISBN : 9780387363189

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Multiscale Modeling and Simulation of Composite Materials and Structures by Young Kwon,David H. Allen,Ramesh R. Talreja Pdf

This book presents the state-of-the-art in multiscale modeling and simulation techniques for composite materials and structures. It focuses on the structural and functional properties of engineering composites and the sustainable high performance of components and structures. The multiscale techniques can be also applied to nanocomposites which are important application areas in nanotechnology. There are few books available on this topic.

Bone Tissue Engineering

Author : Jeffrey O. Hollinger,Thomas A. Einhorn,Bruce Doll,Charles Sfeir
Publisher : CRC Press
Page : 500 pages
File Size : 45,8 Mb
Release : 2004-10-14
Category : Medical
ISBN : 9781135501914

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Bone Tissue Engineering by Jeffrey O. Hollinger,Thomas A. Einhorn,Bruce Doll,Charles Sfeir Pdf

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Multiscale Modeling of Cancer

Author : Vittorio Cristini,John Lowengrub
Publisher : Cambridge University Press
Page : 299 pages
File Size : 50,8 Mb
Release : 2010-09-09
Category : Technology & Engineering
ISBN : 9781139491501

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Multiscale Modeling of Cancer by Vittorio Cristini,John Lowengrub Pdf

Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.

Computer Methods in Biomechanics and Biomedical Engineering

Author : J. Middleton,M. L. Jones,G. N. Pande
Publisher : CRC Press
Page : 582 pages
File Size : 47,7 Mb
Release : 1996-03-18
Category : Medical
ISBN : 2919875000

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Computer Methods in Biomechanics and Biomedical Engineering by J. Middleton,M. L. Jones,G. N. Pande Pdf

These papers are concerned with new advances and novel solutions in the areas of biofluids, image-guided surgery, tissue engineering and cardovascular mechanics, implant analysis, soft tissue mechanics, bone remodeling and motion analysis. The contents also feature a special section on dental materials, dental adhesives and orthodontic mechanics. This edition contains many examples, tables and figures, and together with the many references, provides the reader with invaluable information on the latest theoretical developments and applications.

In Situ Tissue Regeneration

Author : Sang Jin Lee,Anthony Atala,James J Yoo
Publisher : Academic Press
Page : 458 pages
File Size : 50,5 Mb
Release : 2016-07-17
Category : Medical
ISBN : 9780128025000

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In Situ Tissue Regeneration by Sang Jin Lee,Anthony Atala,James J Yoo Pdf

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Cardiovascular Solid Mechanics

Author : Jay D. Humphrey
Publisher : Springer Science & Business Media
Page : 766 pages
File Size : 48,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9780387215761

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Cardiovascular Solid Mechanics by Jay D. Humphrey Pdf

This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.

Dexterity and Its Development

Author : Nicholai A. Bernstein
Publisher : Psychology Press
Page : 587 pages
File Size : 49,9 Mb
Release : 2014-04-04
Category : Psychology
ISBN : 9781135693220

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Dexterity and Its Development by Nicholai A. Bernstein Pdf

This is a very unusual book. It brings to the English speaking reader a masterpiece written some 50 years ago by one of the greatest minds of the 20th century--Nicholai Aleksandrovich Bernstein--considered the founder of many contemporary fields of science such as biomechanics, motor control, and physiology of activity. Divided into two parts, this volume's first section is a translation of the Russian book On Dexterity and Its Development. It presents, in a very reader-friendly style, Bernstein's major ideas related to the development and control of voluntary movements in general, and to the notion of dexterity, in particular. Although very few scientific works remain interesting to the reader 50 years after they were written, this volume--now available for the first time in English--is a rare exception to this rule. His ideas are certainly not obsolete. Actually, we are just starting to grasp the depth and breadth of his thinking, especially his analysis of the complex notion of dexterity. The second section provides both a historical and a contemporary perspective on Bernstein's ideas. The original work was directed at a wide audience ranging from specialists in biomechanics and motor behavior, to coaches, neurologists, physical therapists, athletes, and even inquisitive college and high school students. The chapters contributed by contemporary scientists mirror Bernstein's style and present new findings in the areas of biomechanics, motor control, and motor development in a way that would be both understandable to non-specialists in these areas, and informative for professionals working in different areas related to human movement. All those interested in the origins and mechanisms of the production of voluntary movements, irrespective of their educational and professional background, will find this book valuable. In addition, the unique history and composition of this text will make it helpful and attractive to historians and philosophers of science.

Skeletal Muscle Repair and Regeneration

Author : Stefano Schiaffino,Terence Partridge
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 47,7 Mb
Release : 2008-01-18
Category : Medical
ISBN : 9781402067686

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Skeletal Muscle Repair and Regeneration by Stefano Schiaffino,Terence Partridge Pdf

Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.

Biomaterials for Implants and Scaffolds

Author : Qing Li,Yiu-Wing Mai
Publisher : Springer
Page : 466 pages
File Size : 55,7 Mb
Release : 2016-11-30
Category : Technology & Engineering
ISBN : 9783662535745

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Biomaterials for Implants and Scaffolds by Qing Li,Yiu-Wing Mai Pdf

This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.

Organ Manufacturing

Author : Xiaohong Wang
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 48,7 Mb
Release : 2015
Category : Artificial organs
ISBN : 1634829573

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Organ Manufacturing by Xiaohong Wang Pdf

This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.

Tissue Engineering for Artificial Organs, 2 Volume Set

Author : Anwarul Hasan
Publisher : John Wiley & Sons
Page : 762 pages
File Size : 52,9 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527338634

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Tissue Engineering for Artificial Organs, 2 Volume Set by Anwarul Hasan Pdf

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.