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Mycobacteria and Human Disease, 2Ed by John Grange Pdf
The mycobacteria cause two of the world's most serious infections: tuberculosis and leprosy; as well as a range of infections which occur particularly in HIV/AIDS patients. This 2nd edition has been completely revised by John Grange, one of the leading world authorities on the subject, and addresses the major developments in the subject over the last decade: advances in drug treatment of leprosy, tuberculosis and other mycobacterial diseases; the introduction of monoclonal antibodies; cell cloning techniques, and genetic engineering techniques. 'Mycobacteria and Human Disease' provides a comprehensive review of the mycobacteria, their place in the environment, the way in which they interact with the living host, the nature of the diseases they cause and the available means of diagnosing, preventing and curing such disease, for medical microbiologists in practice and training.
Worms and Human Disease by Ralph Muller,Derek Wakelin Pdf
This second edition of the popular advanced student textbook (previously published as Worms and Disease: A Manual of Medical Helminthology) has been thoroughly updated and revised since it was first published in 1975. It is an authoritative handbook covering all human helminth infections with particular emphasis on diagnosis, treatment, clinical manifestations, pathogenesis, epidemiology and control. Practical guidelines are given for estimating the clinical and public significance of helminthiases, vital in areas where the majority of inhabitants are infected with many helminths but only a few are sick.
Detailed information dealing with the ecology of mycobacteria is derived from a variety of different scientific fields such as botany, biochemistry, genetics, immunology, microbiology and epidemiology. This text attempts to evaluate this information from an ecological point of view and to develop a strategy for the prevention of tuberculosis and other mycobacterioses based on the ecological behaviour of mycobacteria, especially the potentially pathogenic species capable of either growth in the environment or provoking disease. Regarding the interests of the developing countries, special attention is paid to the ecology of Mycobacterium leprae and to the supporting effect of accompanying mycobacteria in its pathogenicity. On a more positive side, environmental mycobacteria play an important role in the ecology of moorland dragonflies.
The Ecology of Mycobacteria: Impact on Animal's and Human's Health by Jindrich Kazda,Ivo Pavlik,Joseph O. Falkinham III,Karel Hruska Pdf
habitats and the overlapping of these biotopes by humans and animals contributed to the spread of mycobacteria and perhaps to their convergence to pathogenicity. It was not our intention to present a compendium covering all published results, but rather to issue a “readable” book, which is illustrative and thus focused on the principle facts. The increase in the number of Editors has allowed the sharing of original experiences regarding the ecology of mycobacteria, published here for the ?rst time in some cases. The supplemented edition should serve as a guide to these discoveries and also contribute to an understanding of clinically signi?cant species in human and animal medicine. Borstel, Germany, January 2009 Jindrich Kazda Editors’Comments The editors responsible for the chapters are listed under the title of each chapter. Authors are listed under the titles of subchapters. The references are listed as they appear in the databases Reference Manager (Thomson Reuters, Philadelphia) as imported from Web of Science (Thomson Reuters, Philadelphia) or PubMed (Medline, NLM Bethesda). A few citations, not indexed, were cited according to the reprints or books available. This principle resulted in minor differences in the titles (not all reference titles are in English, some references have capitalized title words, not all species names are according to the contemporary nomenclature and in italics). Some journals are cited with abbreviated titles, some in full, as available in the source databases. These differences were left in the format of the database.
Foodborne Infections and Intoxications by J. Glenn Morris Jr.,Duc J. J. Vugia Pdf
Foodborne Infections and Intoxications, Fifth Edition brings together up-to-date, relevant interdisciplinary expertise of 70 authors presenting foodborne disease pathogens and toxins, microbiology, disease diagnosis and treatment, epidemiology, and disease prevention in the context of public health and food safety regulation. Beginning with the estimation of foodborne disease burden at the international scale, this book dives deep in foodborne disease outbreak investigation, food safety risk assessment, and molecular analysis, together with detailed descriptions of the major bacteria, viruses, parasites, and toxins associated with foodborne illness. This new edition also emphasizes development of risk-based approaches to food safety and safety regulation implementation. This book is a valuable scientific resource for understanding causes and management of foodborne diseases. The new edition offers the latest knowledge and updates on foodborne infections and intoxications and food safety for multiple generations of students, investigators, public health workers, food scientists, and food safety practitioners. Covers all major foodborne pathogens and toxins, and new emerging pathogens Includes newly updated information on the Food Safety Modernization Act (FSMA) and other regulatory approaches to food safety Includes new chapters on foodborne disease outbreak investigations and use of molecular epidemiologic techniques in these investigations
Tuberculosis E-Book by H. Simon Schaaf,Alimuddin Zumla Pdf
This book provides all the vital information you need to know about tuberculosis, especially in the face of drug-resistant strains of the disease. Coverage includes which patient populations face an elevated risk of infection, as well as which therapies are appropriate and how to correctly monitor ongoing treatment so that patients are cured. Properly administer screening tests, interpret their results, and identify manifestations of the disease, with authoritative guidance from expert clinicians from around the world. Discusses screening tests for tuberculosis so you can interpret their results and identify not only common manifestations of the disease, but also those that are comparatively rare—such as tuberculosis in pregnant women. Covers all clinical aspects of tuberculosis in children, including current practices on managing those infected with HIV. Provides details on how best to interact with the public health system in both industrialized and developing countries. Addresses the social aspects of tuberculosis and presents the latest advances on new and potential vaccines against tuberculosis. Offers the expertise of internationally recognized tuberculosis clinicians to provide you with well-rounded, global coverage. Features numerous illustrations to provide clear and detailed depictions of rare manifestations of tuberculosis.
A review of the original edition of The Burdens of Disease that appeared in ISIS stated, "Hays has written a remarkable book. He too has a message: That epidemics are primarily dependent on poverty and that the West has consistently refused to accept this." This revised edition confirms the book's timely value and provides a sweeping approach to the history of disease. In this updated volume, with revisions and additions to the original content, including the evolution of drug-resistant diseases and expanded coverage of HIV/AIDS, along with recent data on mortality figures and other relevant statistics, J. N. Hays chronicles perceptions and responses to plague and pestilence over two thousand years of western history. Disease is framed as a multidimensional construct, situated at the intersection of history, politics, culture, and medicine, and rooted in mentalities and social relations as much as in biological conditions of pathology. This revised edition of The Burdens of Disease also studies the victims of epidemics, paying close attention to the relationships among poverty, power, and disease.
Author : Michael J. Dark Publisher : Elsevier Inc. Chapters Page : 568 pages File Size : 52,7 Mb Release : 2013-03-06 Category : Medical ISBN : 9780128073742
Foodborne Infections and Intoxications by Michael J. Dark Pdf
Mycobacteria are well-known human and animal pathogens. The most common foodborne Mycobacterium is M. bovis. This causes a range of lesions, from classic pulmonary tuberculosis to cervical lymphadenitis, gastroenteritis, genitourinary infections, and disseminated disease. The disease incidence in humans is generally correlated with the prevalence in cattle. Other species, termed “non-tuberculous mycobacteria,” can (or are suspected to) cause foodborne and waterborne disease. Treatment is difficult and prolonged, unless surgical excision is possible.
Factors Associated with Mycobacterium Avium Complex Infection and Pulmonary Disease Progression by Phung Kim Lam Pdf
Mycobacterium avium complex (MAC), a resilient and ubiquitous non-tuberculous mycobacterium (NTM) commonly found in water and soil, is a pathogen that can cause infection or pulmonary disease (MAC-PD). MAC-PD is an emerging condition but remains under-studied, particularly in characterizing infection, disease progression, and risk factors. Initially, a case-control study of San Diego patients examined factors associated with being culture-positive for MAC (n=62), relative to being positive for rapid-grower (n=32) and culture-negative (n=44). The majority of MAC+ patients had underlying lung diseases (82% with abnormal radiographs) but only one-third was suspected of having MAC disease (32% underwent treatment). Compared to the culture-negative group, the MAC+ group was 3.4 (95% CI: 1.2-9.7) times more likely to be born in coastal states. Compared to the more healthy rapid-growers group, the MAC+ group had significantly higher bacilli load (23% vs. 16% smear-positive), lower average body mass index (BMI, 22 vs. 28 kg/m2), and lower average serum albumin concentration (30 vs. 33 g/l). Subsequently, survival analysis of a national study focused on factors associated with MAC-PD improvement in 95 HIV-negative older adults. Originally enrolled in a trial of interferon-gamma treatment, all subjects received standard mycobacterial drug therapy three-times-weekly (TIW), instead of daily, for one year. TIW response was low (e.g., 44% had culture improvement). Patients with non-cavitary disease had 4.0 (95% CI: 1.7-9.2) times greater culture and 4.9 (95% CI: 1.9-13.0) times greater CT response rates than those with cavitary disease. Older, smear-negative, or previously untreated subjects, and those with longer ethambutol use or without severe pulmonary presentations also had greater improvement. In unadjusted analyses, culture improvement was significantly associated with use of multivitamin (HR=2.4), vitamin E (HR=3.2), and calcium supplements (HR=4.2), BMI e"9 kg/m2 (HR=2.2), and serum albumin e"6 g/l (HR=2.4); albumin e"4 g/l was also associated with CT improvement (HR=4.5). However, after adjusting for cavitary disease and other indicators of disease severity, these associations diminished significantly. Only use of calcium supplements remained independently associated with culture improvement (HR=4.0; 95% CI=1.6-9.7), but cause and effect cannot be assumed. Further research is needed to validate these findings, particularly under long-term treatment
Nontuberculous Mycobacterial Disease by David E. Griffith Pdf
This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.
