Mycobacterium Tuberculosis Pathogenesis Infection Prevention And Treatment

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Mycobacterium Tuberculosis Pathogenesis, Infection Prevention and Treatment

Riccardo Miggiano,Menico Rizzi,Davide M Ferraris
Mycobacterium Tuberculosis Pathogenesis Infection Prevention and Treatment Book PDF

Author : Riccardo Miggiano,Menico Rizzi,Davide M Ferraris
Publisher : Mdpi AG
Page : 128 pages
File Size : 43,5 Mb
Release : 2020-10
Category : Science
ISBN : 3039366580

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Mycobacterium Tuberculosis Pathogenesis, Infection Prevention and Treatment by Riccardo Miggiano,Menico Rizzi,Davide M Ferraris Pdf

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.

Mycobacterium Tuberculosis Pathogenesis, Infection Prevention and Treatment

Davide Maria Ferraris,Riccardo Miggiano,Menico Rizzi
Mycobacterium Tuberculosis Pathogenesis Infection Prevention and Treatment Book PDF

Author : Davide Maria Ferraris,Riccardo Miggiano,Menico Rizzi
Publisher : Unknown
Page : 128 pages
File Size : 53,8 Mb
Release : 2020
Category : Electronic
ISBN : 3039366599

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Mycobacterium Tuberculosis Pathogenesis, Infection Prevention and Treatment by Davide Maria Ferraris,Riccardo Miggiano,Menico Rizzi Pdf

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.

Tuberculosis in Adults and Children

Dorothee Heemskerk,Maxine Caws,Ben Marais,Jeremy Farrar
Tuberculosis in Adults and Children Book PDF

Author : Dorothee Heemskerk,Maxine Caws,Ben Marais,Jeremy Farrar
Publisher : Springer
Page : 66 pages
File Size : 42,9 Mb
Release : 2015-07-17
Category : Medical
ISBN : 9783319191324

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Tuberculosis in Adults and Children by Dorothee Heemskerk,Maxine Caws,Ben Marais,Jeremy Farrar Pdf

This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.

Tuberculosis

Barry R. Bloom
Tuberculosis Book PDF

Author : Barry R. Bloom
Publisher : Unknown
Page : 664 pages
File Size : 52,9 Mb
Release : 1994
Category : Mycobacterium tuberculosis
ISBN : UOM:39015035754277

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Tuberculosis by Barry R. Bloom Pdf

The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.

Disease Control Priorities, Third Edition (Volume 6)

King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Disease Control Priorities Third Edition Volume 6 Book PDF

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 40,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Tuberculosis: Pathogenesis and Control

Megan Durham
Tuberculosis Pathogenesis and Control Book PDF

Author : Megan Durham
Publisher : Foster Academics
Page : 249 pages
File Size : 52,9 Mb
Release : 2019-06-24
Category : Medical
ISBN : 1632426927

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Tuberculosis: Pathogenesis and Control by Megan Durham Pdf

Tuberculosis (TB) is an infectious disease primarily affecting the lungs. It is caused by a species of pathogenic bacteria called mycobacterium tuberculosis. TB infection converts into disease when the immune system defenses are overcome by bacilli that begin to multiply. Tuberculosis can also reoccur after treatment especially in patients with HIV. A short course treatment of TB involves the use of antibiotics such as isoniazid, rifampicin, ethambutol, etc. These are known as first-line drugs. A series of second-line drugs may also be used in case the first-line drugs prove to be inefficient to treat the disease. This book discusses the fundaments as well as modern approaches of tuberculosis pathogenesis, control and treatment. The topics included herein are of utmost significance and bound to provide incredible insights to readers.

Tuberculosis

M. Monir Madkour
Tuberculosis Book PDF

Author : M. Monir Madkour
Publisher : Springer Science & Business Media
Page : 974 pages
File Size : 43,9 Mb
Release : 2003-11-18
Category : Medical
ISBN : 3540014411

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Tuberculosis by M. Monir Madkour Pdf

A comprehensive textbook on tuberculosis that covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. The main part of the book comprises very detailed and richly illustrated clinical chapters. The copious images are the advantage of this book. Chapters on new methods and treatments and on animal tuberculosis are included. The material is based on a wealth of experience in tuberculosis as seen in endemic countries such as Saudi Arabia that enjoy free access to advanced investigative and therapeutic facilities. This coexistence of endemicity of the disease and state-of-the-art facilities is rare in poor and developing countries or in rich and developed nations. This multidisciplinary volume is ideal for all clinicians, laboratory and research workers, epidemiologists, university teachers and students, health care planners and international organizations involved in world health and infectious disease.

Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions

Seyed Ehtesham Hasnain,Nasreen Z. Ehtesham,Sonam Grover
Mycobacterium Tuberculosis Molecular Infection Biology Pathogenesis Diagnostics and New Interventions Book PDF

Author : Seyed Ehtesham Hasnain,Nasreen Z. Ehtesham,Sonam Grover
Publisher : Springer Nature
Page : 524 pages
File Size : 50,7 Mb
Release : 2019-11-30
Category : Medical
ISBN : 9789813294134

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Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions by Seyed Ehtesham Hasnain,Nasreen Z. Ehtesham,Sonam Grover Pdf

This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.

Tuberculosis: Pathogenesis, Diagnosis and Treatment

June Middleton
Tuberculosis Pathogenesis Diagnosis and Treatment Book PDF

Author : June Middleton
Publisher : American Medical Publishers
Page : 0 pages
File Size : 48,9 Mb
Release : 2023-09-26
Category : Health & Fitness
ISBN : 9798887405391

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Tuberculosis: Pathogenesis, Diagnosis and Treatment by June Middleton Pdf

Tuberculosis (TB) is a contagious disease that mainly causes damage to the lungs. This disease is caused by the Mycobacterium tuberculosis (Mtb) bacteria. It can be transmitted from an infected person to a healthy person, through tiny droplets released while sneezing and coughing. Some common symptoms of TB include coughing for more than three weeks, chest pain, or pain while coughing and breathing, fatigue, fever, and loss of appetite. Several conditions like diabetes, severe kidney disease, malnutrition, and HIV makes a person more prone to TB bacteria by reducing the capacity of immune system to work efficiently. Tuberculosis can cause death if left untreated. Furthermore, it is a leading cause of complications like spinal pain, swelling in the membranes covering the brain, heart disorders, and liver or kidney problems. Its diagnosis starts with a physical examination of lymph nodes for swelling. Other diagnostic methods include blood tests, imaging tests and sputum tests. DOT (directly observed therapy) is a predominant treatment of TB. This book includes some of the vital pieces of work being conducted across the world, on various topics related to tuberculosis. It will provide comprehensive knowledge to the readers on the pathogenesis, diagnosis and treatment of this disease.

Understanding the Pathogenesis of Tuberculosis (T.B.) for the Discovery of New Therapeutic Targets at Molecular Level: Recent Perspectives for an Old Disease.

Dr.Hakim Saboowala
Understanding the Pathogenesis of Tuberculosis T B for the Discovery of New Therapeutic Targets at Molecular Level Recent Perspectives for an Old Disease Book PDF

Author : Dr.Hakim Saboowala
Publisher : Dr.Hakim Saboowala
Page : 60 pages
File Size : 42,8 Mb
Release : 2020-07-06
Category : Medical
ISBN : 8210379456XXX

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Understanding the Pathogenesis of Tuberculosis (T.B.) for the Discovery of New Therapeutic Targets at Molecular Level: Recent Perspectives for an Old Disease. by Dr.Hakim Saboowala Pdf

Understanding the Pathogenesis of Tuberculosis (T.B.) for the Discovery of New Therapeutic Targets at Molecular Level: Recent Perspectives for an Old Disease. The history of tuberculosis (TB) mixtures with the history of humanity since TB is one of the oldest infectious diseases affecting mankind. Bone TB was identified in 4000 years old skeletons, from Europe and Middle East, as the cause of death. Tuberculosis is an ancient infectious disease that remains a threat for public health around the world. Although the etiological agent as well as tuberculosis pathogenesis is well known, the molecular mechanisms underlying the host defense to the bacilli remain elusive. An attempt has been made in this Booklet to focus on the innate immunity of this disease reviewing: 1. Well-established and consensual mechanisms like: o Mycobacterium tuberculosis interference with phagosome maturation, Less consensual mechanism like: o Nitric oxide production, and 3. New mechanisms, such as: o Mycobacteria translocation to the cytosol, o Autophagy, and Apoptosis/Necrosis proposed mainly during the last decade. …Dr. H. K. Saboowala. M.B.(Bom). M. R. S. H. (London).

WHO consolidated guidelines on tuberculosis

World Health Organization
WHO consolidated guidelines on tuberculosis Book PDF

Author : World Health Organization
Publisher : World Health Organization
Page : 60 pages
File Size : 41,9 Mb
Release : 2022-08-12
Category : Medical
ISBN : 9789240055889

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WHO consolidated guidelines on tuberculosis by World Health Organization Pdf

One of the targets of the Sustainable Development Goals (SDGs) for the period 2015-2030 is to end the global TB epidemic. In line with this target, the WHO End TB Strategy, approved by the World Health Assembly in 2014, calls for a 90% reduction in TB deaths and an 80% decrease in the TB incidence rate by 2030. The strategy emphasizes the need for prevention across all approaches, including infection prevention and control (IPC) in health care services and other settings where the risk of Mycobacterium tuberculosis transmission is high. IPC practices are vital to reduce the risk of M. tuberculosis transmission, by reducing the concentration of infectious droplet nuclei in the air and the exposure of susceptible individuals to such aerosols. Initial WHO recommendations on TB IPC focused primarily on decreasing the risk of transmission in health care facilities in resource-limited settings.17,18 These initial recommendations were then expanded in 2009 to provide further guidance on the use of specific measures for health care facilities, congregate settings and households. After the 2009 guidelines had been in effect for almost 10 years, the need for an update was anticipated, to provide a revised evidence assessment, reinforcing earlier recommendations and linking to core components of effective IPC programmes overall. The present updated guidelines also stress the importance of implementing IPC measures in a systematic and objective way that prioritizes consideration of the hierarchy of IPC controls.

Tuberculosis: A Clinical Practice Guide

Rafael Laniado-Laborín
Tuberculosis A Clinical Practice Guide Book PDF

Author : Rafael Laniado-Laborín
Publisher : Bentham Science Publishers
Page : 207 pages
File Size : 55,8 Mb
Release : 2020-12-01
Category : Medical
ISBN : 9789811488498

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Tuberculosis: A Clinical Practice Guide by Rafael Laniado-Laborín Pdf

Tuberculosis is an infection of the lungs caused by Mycobacterium tuberculosis and related species. It is prevalent in tropical regions and continues to occur in more than 10 million new individuals annually and despite many advances in medicine, still results in 1.3 million deaths annually. This clinical practice handbook presents information on all topics related to the disease, including its epidemiology, microbiology, clinical features, diagnostic procedures, treatments, BCG vaccination and infection control in health facilities. Special topics such as the treatment of tuberculosis is pediatric patients, surgery, multi-drug resistance and adverse reactions to tuberculosis drugs are also covered. Information is presented in 16 simple easy-to read chapters with key figures, tables and references that help to explain relevant topics. Tuberculosis: A Clinical Practice Guide is an ideal reference manual for medical students and healthcare personnel seeking information about tuberculosis.

Nanotechnology Based Approaches for Tuberculosis Treatment

Prashant Kesharwani
Nanotechnology Based Approaches for Tuberculosis Treatment Book PDF

Author : Prashant Kesharwani
Publisher : Academic Press
Page : 284 pages
File Size : 53,5 Mb
Release : 2020-06-10
Category : Business & Economics
ISBN : 9780128226117

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Nanotechnology Based Approaches for Tuberculosis Treatment by Prashant Kesharwani Pdf

Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Tuberculosis

Mario C. Raviglione
Tuberculosis Book PDF

Author : Mario C. Raviglione
Publisher : CRC Press
Page : 408 pages
File Size : 52,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420090239

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Tuberculosis by Mario C. Raviglione Pdf

Every second a new person is exposed to tuberculosis (TB). Each untreated TB-infected person will infect 10-15 people every year. Following the success of its predecessor, this new edition of Tuberculosis: The Essentials scrutinizes the new discoveries and observations of the key aspects of the disease. Recognized world experts provide a concise, state-of-the-art review of the 15 essential elements of TBsupply an international, current view of the epidemiology, pathophysiology, diagnosis, and treatment methodsdiscuss the emerging threat of XDR-TB and the HIV/AIDS factorassess advances in TB research such as new drugs and vaccinesreflect on the progress of the "Stop TB" strategy. See What’s New in the Fourth Edition: Updated chapters on epidemiology and pathogenesis provide new insights on TB infection and disease Updated chapters on diagnosis and treatment cover new tests and molecular detection methods Information on developing effective regiments and discussion of situations deserving specific precautions Coverage of adherence issues The book book is an essential guide for everybody working in the field of TB, from specialists to nurses and students, both from a clinical and public health perspective.

Case Studies in Infectious Disease: Mycobacterium Tuberculosis

Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward
Case Studies in Infectious Disease Mycobacterium Tuberculosis Book PDF

Author : Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward
Publisher : Garland Science
Page : 21 pages
File Size : 43,9 Mb
Release : 2009-12
Category : Medical
ISBN : 9781136986413

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Case Studies in Infectious Disease: Mycobacterium Tuberculosis by Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward Pdf

Case Studies in Infectious Disease: Mycobacterium tuberculosis presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.