N Acetylcysteine Boost Glutathione Heal Your Liver And Soothe Your Brain With The Power Of Nac

Author : Richard Eugene Frye,Michael Berk
Publisher : Springer
Page : 394 pages
File Size : 48,6 Mb
Release : 2018-09-20
Category : Medical
ISBN : 9789811053115

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The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine by Richard Eugene Frye,Michael Berk Pdf

Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

Author : New York (State) General Laws Committee
Publisher : Wentworth Press
Page : 312 pages
File Size : 45,5 Mb
Release : 2019-03-26
Category : History
ISBN : 1011552019

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Report: On General Laws Relative To Combinations Commonly Known As Trusts, 1888-89; by New York (State) General Laws Committee Pdf

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 44,5 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Janusz Marcinkiewicz,Stephen W. Schaffer
Publisher : Springer
Page : 905 pages
File Size : 52,7 Mb
Release : 2015-04-01
Category : Science
ISBN : 9783319151267

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Taurine 9 by Janusz Marcinkiewicz,Stephen W. Schaffer Pdf

Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May 2014. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.

Author : Jolene Brighten
Publisher : HarperCollins
Page : 384 pages
File Size : 52,7 Mb
Release : 2019-01-29
Category : Health & Fitness
ISBN : 9780062847119

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Beyond the Pill by Jolene Brighten Pdf

Out of the 100 million women—almost 11 million in the United States alone—who are on the pill, roughly 60 percent take it for non-contraceptive reasons like painful periods, endometriosis, PCOS, and acne. While the birth control pill is widely prescribed as a quick-fix solution to a variety of women’s health conditions, taking it can also result in other more serious and dangerous health consequences. Did you know that women on the pill are more likely to be prescribed an antidepressant? That they are at significantly increased risk for autoimmune disease, heart attack, thyroid and adrenal disorders, and even breast and cervical cancer? That the pill can even cause vaginal dryness, unexplained hair loss, flagging libido, extreme fatigue, and chronic infection. As if women didn’t have enough to worry about, that little pill we’re taking to manage our symptoms is only making things worse. Jolene Brighten, ND, author of the groundbreaking new book BEYOND THE PILL, specializes in treating women’s hormone imbalances caused by the pill and shares her proven 30-day program designed to reverse the myriad of symptoms women experience every day—whether you choose to stay on the pill or not. The first book of its kind to target the birth control pill and the scientifically-proven symptoms associated with taking it, BEYOND THE PILL is an actionable plan for taking control, and will help readers: • Locate the root cause of their hormonal issues, like estrogen dominance, low testosterone, and low progesterone • Discover a pain-free, manageable period free of cramps, acne, stress, or PMS without the harmful side effects that come with the pill • Detox the liver, support the adrenals and thyroid, heal the gut, reverse metabolic mayhem, boost fertility, and enhance mood • Transition into a nutrition and supplement program, with more than 30 hormone-balancing recipes Featuring simple diet and lifestyle interventions, BEYOND THE PILL is the first step to reversing the risky side effects of the pill, finally finding hormonal health, and getting your badass self back.

Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 41,8 Mb
Release : 2014-09-17
Category : Medical
ISBN : 9781466567573

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Antioxidants in Sport Nutrition by Manfred Lamprecht Pdf

The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Author : Alan R. Gaby
Publisher : Unknown
Page : 0 pages
File Size : 44,8 Mb
Release : 2024-05-05
Category : Electronic
ISBN : 0982885016

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Nutritional Medicine, Third Edition by Alan R. Gaby Pdf

Textbook regarding the use of diet, nutritional supplements, and other natural substances for the prevention and treatment of disease.

Author : Anonim
Publisher : Unknown
Page : 500 pages
File Size : 41,6 Mb
Release : 1995
Category : Polycyclic aromatic hydrocarbons
ISBN : UOM:39015038438415

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Toxicological Profile for Polycyclic Aromatic Hydrocarbons by Anonim Pdf

Author : Alfonso Pompella,Alessandro Corti
Publisher : Frontiers Media SA
Page : 144 pages
File Size : 46,6 Mb
Release : 2015-07-17
Category : Pharmacology
ISBN : 9782889195954

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The Changing Faces of Glutathione, a Cellular Protagonist by Alfonso Pompella,Alessandro Corti Pdf

Glutathione (GSH) has been described for a long time just as a defensive reagent against the action of toxic xenobiotics (drugs, pollutants, carcinogens), both directly and as a cofactor for GSH transferases. As a prototype antioxidant, it has been involved in cell protection from the noxious effect of excess oxidant stress, both directly and as a cofactor of glutathione peroxidases. In addition, it has long been known that GSH is capable of forming disulfide bonds with cysteine residues of proteins, and the relevance of this mechanism ("S-glutathionylation") in regulation of protein function has been well documented in a number of research fields. Rather paradoxically, it has also been highlighted that GSH—and notably its catabolites, as originated by metabolism by gamma-glutamyltransferase—can promote oxidative processes, by participating in metal ion-mediated reactions eventually leading to formation of reactive oxygen species and free radicals. Also, a fundamental role of GSH has been recognized in the storage and transport of nitric oxide (NO), in the form of S-nitrosoglutathione (GSNO). The significance of GSH as a major factor in regulation of cell life, proliferation, and death, can be regarded as the integrated result of all these roles, as well as of more which are emerging in diverse fields of biology and pathophysiology. Against this background, modulation of GSH levels and GSH-related enzyme activities represents a fertile field for experimental pharmacology in numerous and diverse perspectives of animal, plant and microbiologic research. This research topic includes 14 articles, i.e. 4 Opinion Articles, 6 Reviews, and 4 Original Research Articles. The contributions by several distinguished research groups, each from his own standpoint of competence and expertise, provide a comprehensive and updated view over the diverse roles, the changing faces of GSH and GSH-related enzymes in cell’s health, disease and death.

Author : Halina Maria Ekiert,Kishan Gopal Ramawat,Jaya Arora
Publisher : Springer
Page : 861 pages
File Size : 44,8 Mb
Release : 2022-06-26
Category : Science
ISBN : 3030781593

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Plant Antioxidants and Health by Halina Maria Ekiert,Kishan Gopal Ramawat,Jaya Arora Pdf

This book provides a comprehensive reference guide to plant-derived antioxidants, their beneficial effects, mechanisms of action, and role in disease prevention and improving general health (anti-ageing effect). The content is divided into three main parts, the first of which covers various antioxidants (such as polyphenols, carotenoids, tocopherols, tocotrienols, glutathione, ascorbic acid), their origins, plant biochemistry and industrial utilization. In turn, the book’s second, main part focuses on antioxidants’ beneficial health effects, explains biochemical fundamentals such as the free radical theory and oxidative stress, and discusses antioxidants’ role in e.g. cancer, cardiovascular diseases, inflammation, degenerative diseases and ageing. The third part reviews general laboratory methods for antioxidant screening, preservation and determination. Written by an international team of experts, this highly interdisciplinary book will benefit a broad range of health professionals and researchers working in biochemistry, biotechnology, nutrition, plant science and food chemistry. It offers an indispensable, up-to-date guide for anyone interested in antioxidants and the role of a plant-based diet in disease prevention and control

Author : John A. Kellum,Rinaldo Bellomo,Claudio Ronco
Publisher : Oxford University Press
Page : 329 pages
File Size : 50,8 Mb
Release : 2016
Category : Medical
ISBN : 9780190225537

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Continuous Renal Replacement Therapy by John A. Kellum,Rinaldo Bellomo,Claudio Ronco Pdf

Continuous Renal Replacement Therapy (CRRT) is the standard of care for management of critically ill patients with acute renal failure. Part of the Pittsburgh Critical Care series, Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance about this treatment modality, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice. Organized into sections on theory, practice, special situations, and organizational issues, this volume provides a complete view of CRRT theory and practice. Tables summarize and highlight key points, and key studies and trials are included in each chapter. The second edition has been updated to include a new chapter on the use of biomarkers to aid in patient selection and timing, extensive revisions on terminology and nomenclature to match current standards, and the most up-to-date information on newly developed CRRT machines.

Author : B. Trémillon
Publisher : Springer Science & Business Media
Page : 291 pages
File Size : 46,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401021234

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Chemistry in Non-Aqueous Solvents by B. Trémillon Pdf

Arising no doubt from its pre-eminence as a natural liquid, water has always been considered by chemists as the original solvent in which very varied chemical reactions can take place, both for preparational and for analytical purposes. This explains the very long-standing interest shown in the study of aqueous solutions. In this con nection, it must be stressed that the theory of Arrhenius and Ostwald (1887-1894) on electrolytic dissociation, was originally devised solely for solutions in water and that the first true concept of acidity resulting from this is linked to the use of this solvent. The more recent development of numerous physico-chemical measurement methods has made possible an increase of knowledge in this area up to an extremely advanced degree of systematization. Thus today we have available both a very large amount of experimental data, together with very refined methods of deduction and of quantitative treatment of chemical reactions in solution which enable us to make the fullest use of this data. Nevertheless, . it appears quite evident at present that there are numerous chemical processes which cannot take place in water, and that its use as a solvent imposes 2 INTRODUCTION limitations. In order to overcome these limitations, it was natural that interest should be attracted to solvents other than water and that the new possibilities thus opened up should be explored.

Author : Francis Marion Pottenger
Publisher : Unknown
Page : 0 pages
File Size : 50,8 Mb
Release : 2005
Category : Cats
ISBN : OCLC:1349250064

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Pottenger's Cats by Francis Marion Pottenger Pdf

Author : Jose Antonio Morales-Gonzalez
Publisher : BoD – Books on Demand
Page : 516 pages
File Size : 54,7 Mb
Release : 2013-05-22
Category : Science
ISBN : 9789535111238

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Oxidative Stress and Chronic Degenerative Diseases by Jose Antonio Morales-Gonzalez Pdf

This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.

Author : Cavin Balaster
Publisher : Unknown
Page : 183 pages
File Size : 41,5 Mb
Release : 2017-01-04
Category : Brain
ISBN : 099950021X

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How to Feed a Brain by Cavin Balaster Pdf

"After sustaining his severe injury, the author devoted years to researching and connecting with doctors, nutritionists, practitioners, neuroscientists, and more to learn how to optimize brain recovery and function. How to Feed a Brain is the culmination of the nutritional tools that he has learned through this journey and used in his own recovery. This book is not only for someone with a brain injury or disease, but also for anyone seeking to improve their brain. " -- Publisher.