Nanobiomaterials In Antimicrobial Therapy

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Nanobiomaterials in Antimicrobial Therapy

Alexandru Grumezescu
Nanobiomaterials in Antimicrobial Therapy Book PDF

Author : Alexandru Grumezescu
Publisher : William Andrew
Page : 576 pages
File Size : 41,5 Mb
Release : 2016-03-08
Category : Science
ISBN : 9780323428873

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Nanobiomaterials in Antimicrobial Therapy by Alexandru Grumezescu Pdf

Nanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A methodical approach to this highly relevant subject for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Nanostructures for Antimicrobial Therapy

Anton Ficai,Alexandru Mihai Grumezescu
Nanostructures for Antimicrobial Therapy Book PDF

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 50,9 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

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Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Antimicrobial Nanoarchitectonics

Alexandru Mihai Grumezescu
Antimicrobial Nanoarchitectonics Book PDF

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 574 pages
File Size : 51,5 Mb
Release : 2017-06-22
Category : Technology & Engineering
ISBN : 9780323527347

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Antimicrobial Nanoarchitectonics by Alexandru Mihai Grumezescu Pdf

Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems Includes case studies, showing how particular bionanomaterials have been used to cure infections Explains the central role that nanotechnology plays in modern antimicrobial therapy Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance

Muthupandian Saravanan,Hamed Barabadi,Ebrahim Mostafavi,Thomas J Webster
Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance Book PDF

Author : Muthupandian Saravanan,Hamed Barabadi,Ebrahim Mostafavi,Thomas J Webster
Publisher : Elsevier
Page : 790 pages
File Size : 53,6 Mb
Release : 2022-06-22
Category : Technology & Engineering
ISBN : 9780323998109

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Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance by Muthupandian Saravanan,Hamed Barabadi,Ebrahim Mostafavi,Thomas J Webster Pdf

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Nanostructures for Antimicrobial and Antibiofilm Applications

Ram Prasad,Busi Siddhardha,Madhu Dyavaiah
Nanostructures for Antimicrobial and Antibiofilm Applications Book PDF

Author : Ram Prasad,Busi Siddhardha,Madhu Dyavaiah
Publisher : Springer Nature
Page : 461 pages
File Size : 55,5 Mb
Release : 2020-05-12
Category : Science
ISBN : 9783030403379

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Nanostructures for Antimicrobial and Antibiofilm Applications by Ram Prasad,Busi Siddhardha,Madhu Dyavaiah Pdf

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.

Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer

Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik
Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer Book PDF

Author : Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik
Publisher : IGI Global
Page : 559 pages
File Size : 47,5 Mb
Release : 2021-02-12
Category : Medical
ISBN : 9781799850502

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Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer by Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik Pdf

Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Functionalized Nanomaterials for the Management of Microbial Infection

Rabah Boukherroub,Sabine Szunerits,Djamel Drider
Functionalized Nanomaterials for the Management of Microbial Infection Book PDF

Author : Rabah Boukherroub,Sabine Szunerits,Djamel Drider
Publisher : William Andrew
Page : 338 pages
File Size : 52,7 Mb
Release : 2016-12-14
Category : Technology & Engineering
ISBN : 9780323417372

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Functionalized Nanomaterials for the Management of Microbial Infection by Rabah Boukherroub,Sabine Szunerits,Djamel Drider Pdf

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. Provides the information users need to integrate antibacterial nanoparticles into future treatments Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection

Nano-Antimicrobials

Nicola Cioffi,Mahendra Rai
Nano Antimicrobials Book PDF

Author : Nicola Cioffi,Mahendra Rai
Publisher : Springer Science & Business Media
Page : 563 pages
File Size : 49,5 Mb
Release : 2012-02-24
Category : Technology & Engineering
ISBN : 9783642244285

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Nano-Antimicrobials by Nicola Cioffi,Mahendra Rai Pdf

There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance have created a pressing need to search for a new generation of antimicrobial agents, which are effective, safe and can be used for the cure of multidrug-resistant microbial infections. Nano-antimicrobials offer effective solutions for these challenges; the details of these new technologies are presented here. The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed.

Microbial Interactions at Nanobiotechnology Interfaces

R. Navanietha Krishnaraj,Rajesh K. Sani
Microbial Interactions at Nanobiotechnology Interfaces Book PDF

Author : R. Navanietha Krishnaraj,Rajesh K. Sani
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 49,6 Mb
Release : 2021-10-26
Category : Technology & Engineering
ISBN : 9781119617174

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Microbial Interactions at Nanobiotechnology Interfaces by R. Navanietha Krishnaraj,Rajesh K. Sani Pdf

MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Recent Progress in Antimicrobial Nanomaterials

Ana María Díez-Pascual
Recent Progress in Antimicrobial Nanomaterials Book PDF

Author : Ana María Díez-Pascual
Publisher : MDPI
Page : 228 pages
File Size : 49,9 Mb
Release : 2021-01-20
Category : Science
ISBN : 9783039439591

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Recent Progress in Antimicrobial Nanomaterials by Ana María Díez-Pascual Pdf

Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.

Silver Nanoparticles for Antibacterial Devices

Huiliang Cao
Silver Nanoparticles for Antibacterial Devices Book PDF

Author : Huiliang Cao
Publisher : CRC Press
Page : 634 pages
File Size : 49,8 Mb
Release : 2017-05-18
Category : Medical
ISBN : 9781315353470

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Silver Nanoparticles for Antibacterial Devices by Huiliang Cao Pdf

Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings together the synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively. With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

Keerti Jain,Javed Ahmad
Nanotheranostics for Treatment and Diagnosis of Infectious Diseases Book PDF

Author : Keerti Jain,Javed Ahmad
Publisher : Academic Press
Page : 414 pages
File Size : 41,8 Mb
Release : 2022-05-21
Category : Medical
ISBN : 9780323914697

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Nanotheranostics for Treatment and Diagnosis of Infectious Diseases by Keerti Jain,Javed Ahmad Pdf

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases. Compiles the latest information on the technological advancements made in the field of nanotechnology for applications in therapeutics Prepares researchers to get ready to fight any emergency which may arise due to the advent of infectious diseases Focuses on the theranostic applications of nanomaterials in infectious diseases Compiles all relevant information to help scientists, researchers and students in understanding the role of nanomaterials and how they could be explored for therapeutic and diagnostic applications

Nano Medicine and Nano Safety

Malay K. Das,Yashwant V. Pathak
Nano Medicine and Nano Safety Book PDF

Author : Malay K. Das,Yashwant V. Pathak
Publisher : Springer Nature
Page : 634 pages
File Size : 50,8 Mb
Release : 2020-12-09
Category : Science
ISBN : 9789811562556

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Nano Medicine and Nano Safety by Malay K. Das,Yashwant V. Pathak Pdf

This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.

Antibiotic Materials in Healthcare

Kokkarachedu Varaprasad,Vimala Kanikireddy,Rotimi Sadiku
Antibiotic Materials in Healthcare Book PDF

Author : Kokkarachedu Varaprasad,Vimala Kanikireddy,Rotimi Sadiku
Publisher : Academic Press
Page : 348 pages
File Size : 53,8 Mb
Release : 2020-05-22
Category : Science
ISBN : 9780128225363

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Antibiotic Materials in Healthcare by Kokkarachedu Varaprasad,Vimala Kanikireddy,Rotimi Sadiku Pdf

Antibiotic Materials in Healthcare provides significant information on antibiotic related issues, accurate solutions, and recent investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced (physical, chemical and biological) properties, an analysis of materials, in vivo and in vitro applications, and their biomedical applications for healthcare. Provides information on all aspects of antibiotic related issues Offers a balanced synthesis of basic and clinical science for each individual case, presenting clinical courses and detailed microbiological information for each infection Describes the prevalence and incidence of global issues and current therapeutic approaches

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases

Mahendra Rai,Kateryna Kon
Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases Book PDF

Author : Mahendra Rai,Kateryna Kon
Publisher : Academic Press
Page : 344 pages
File Size : 50,6 Mb
Release : 2015-05-23
Category : Medical
ISBN : 9780128014714

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Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases by Mahendra Rai,Kateryna Kon Pdf

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections