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Author : Massimo Vitale,Simona Sivori,Michael A. Caligiuri
Publisher : Frontiers Media SA
Page : 256 pages
File Size : 42,9 Mb
Release : 2020-03-24
Category : Electronic
ISBN : 9782889636129
Author : Michael T. Lotze,Angus W. Thomson
Publisher : Academic Press
Page : 660 pages
File Size : 55,9 Mb
Release : 2009-11-12
Category : Medical
ISBN : 0080919294
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 45,5 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Lisa H. Butterfield, PhD,Howard L. Kaufman, MD, FACS,Francesco M. Marincola, MD, FACS
Publisher : Springer Publishing Company
Page : 1339 pages
File Size : 47,7 Mb
Release : 2021-08-25
Category : Medical
ISBN : 9780826137432
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs
Author : Anonim
Publisher : Unknown
Page : 1422 pages
File Size : 53,7 Mb
Release : 1989
Category : Medicine
ISBN : MINN:31951D001728682
Author : Raffaele Badolato,Silvano Sozzani
Publisher : Springer Science & Business Media
Page : 249 pages
File Size : 44,5 Mb
Release : 2006-09-05
Category : Medical
ISBN : 9783764374426
This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety
Publisher : Springer Science & Business Media
Page : 522 pages
File Size : 43,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400943070
IX The International Seminar on the Immunological System as a Target for Toxic Damage was held at The Commission of the European Communities (CEC) in Luxembourg on 6-9 November 1984. It was organized by the CEC and the International Programme on Chemical Safety of UNEP/ILO/WHO with the support of the u. S. Environmental Protection Agency and the National Institute of Environmental Health Sciences - USA and with the participation of the International Society of Immunophar macology. These bodies are actively concerned with the scientific and applied aspects of immunotoxicology. The Seminar consisted of thirty-four invited papers and three major panel discussions covering current and future test strategies for the screening of immunotoxic substances, hypersensitivity and the health implications of immunotoxico logical problems. It was attended by more than 200 scien tists from 27 countries representing all the Member states of the European Economic Community and the six Regions of the World Health Organization. These scientists represented many different disciplines and interests. The Seminar's principal objectives were: a review of recent advances in knowledge concerning the structure, function and dysfunction of the immunological system; - a review of the effects of xenobiotics on the immune system in animals and humans; an examination of the human health implications of immunotoxicity; discussion and critical analysis of the procedures for the assessment of immunological damage, a discussion of needs for the further development of laboratory and epidemiological methods and their validation, and a consideration of current test strategies.
Author : Emanuela Marcenaro,Luigi D. Notarangelo,Jordan S. Orange,Eric Vivier
Publisher : Frontiers Media SA
Page : 245 pages
File Size : 51,8 Mb
Release : 2017-11-29
Category : Electronic book
ISBN : 9782889453504
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Author : Ira Wolinsky
Publisher : CRC Press
Page : 708 pages
File Size : 53,7 Mb
Release : 2022-01-28
Category : Health & Fitness
ISBN : 9781000722161
The third edition of Nutrition in Exercise and Sport has been updated and expanded to include the latest developments in the field. This third edition of a bestseller among sports nutrition and health professionals now fully discusses the role of exercise and nutrition in both wellness and in disease prevention. In addition, new chapters on the history of sports nutrition, antioxidants, vegetarianism, the young athlete, the older athlete, the diabetic athlete, the physically disabled athlete, sports specific nutrient requirements, and body composition changes have been added. Top sports nutrition practitioners and exercise scientists have contributed chapters that provide practical nutritional guidelines for those engaged in various types of physical performance. This book is a one-volume library on sports nutrition for research scientists in applied sports nutrition, dietitians, exercise physiologists, sports medicine physicians, coaches, trainers, athletes, and nutritionists. The first two editions of this book have been widely used in sports nutrition courses. Nutrition in Exercise and Sport is the standard in the field.
Author : Leslie P. Gartner
Publisher : Elsevier Health Sciences
Page : 672 pages
File Size : 45,7 Mb
Release : 2015-11-20
Category : Medical
ISBN : 9780323390682
Thoroughly updated to reflect all of the latest concepts and advances in the field, this concise, extensively illustrated text presents the basic science and clinical application of cellular and molecular biology. Functioning as a combined text and atlas, it is essentially two books for the price of one providing a comprehensive, visually engaging histology education from the ground up. Illustrations, tables, chapter summaries and multiple choice questions facilitate comprehension of concepts, and clinical correlations underscore the practical relevance of the material. Superb illustrations—including photomicrographs, electron micrographs, schematic diagrams and drawings—provide a visual grasp and easier retention of difficult concepts. Clinical correlations throughout the text demonstrate clinical applications and reinforce the idea that histology is pertinent not only to pathology and physiology, but in fact comprises one of the essential bases of clinical practice. New! "Pathological Considerations" section at the end of each chapter. Helpful tables provide an at-a-glance summary statement of key points. Bolded key terms, bulleted lists and chapter summaries emphasize the "need to know" information in every chapter. A combination of USMLE-style questions and image based questions in each chapter.
Author : Steven D. Holladay
Publisher : CRC Press
Page : 386 pages
File Size : 52,7 Mb
Release : 2004-11-15
Category : Medical
ISBN : 1420024035
Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes different models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text concludes with several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology. Using a didactic approach, Developmental Immunotoxicology provides an explanatory overview of this cutting-edge field for toxicologists, immunologists, and developmental biologists. It provides a lucid account of this area of research-proposing answers to some questions and stimulating debate on those questions yet to be addressed by the research community.
Author : Michael T. Lotze,Angus W. Thomson
Publisher : Elsevier
Page : 759 pages
File Size : 41,6 Mb
Release : 2011-05-04
Category : Medical
ISBN : 9780080479330
Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity* Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied
Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 49,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Author : Guido Ferrari,Georgia Tomaras,R. Keith Reeves,Gabriella Scarlatti
Publisher : Frontiers Media SA
Page : 273 pages
File Size : 48,5 Mb
Release : 2020-07-28
Category : Electronic
ISBN : 9782889638901
Author : Christopher B. Wilson,Victor Nizet,Yvonne Maldonado,Jack S. Remington,Jerome O. Klein
Publisher : Elsevier Health Sciences
Page : 1275 pages
File Size : 48,9 Mb
Release : 2015-03-16
Category : Medical
ISBN : 9780323241472
Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 8th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Form a definitive diagnosis and create the best treatment plans possible using evidence-based recommendations and expert guidance from world authorities. Locate key content easily and identify clinical conditions quickly thanks to a consistent, highly user-friendly format now featuring a full-color design with hundreds of illustrations, and fresh perspectives from six new authoritative chapter lead authors. Explore what's changing in key areas such as: - emerging problems and concepts in maternal, fetal, and neonatal infectious diseases - anticipation and recognition of infections occurring in utero, during delivery, and in the neonatal period Stay on the cutting edge of your field with new and improved chapters including: obstetric factors associated with infections of the fetus and newborn infant; human milk; borella infections; tuberculosis; bordetella pertussis and other bordetella sp infections; herpes simplex; toxoplasmosis; pneumocystis and other less common fungal infections; and healthcare-associated infections in the nursery Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome clinical challenges in developing countries where access to proper medical care is limited. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
